Shows / Extend Podcast with Darshan Shah, MD
Extend Podcast with Darshan Shah, MD
Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health…
Episodes
- Extend Podcast with Darshan Shah, MD
212. Dr. Brad Goodman: The Truth About Chronic Back Pain & How to Avoid Surgery
What if the solution to your chronic back pain isn't another prescription, another injection, or even major spine surgery—but identifying exactly where your…
- Extend Podcast with Darshan Shah, MD
211. Emma Heming Willis and Dr. Nicole Beurkens: Why Women Face a Higher Alzheimer's Risk—Menopause, Brain Fog & Prevention
What if the brain fog, forgetfulness, poor sleep, and mood changes so many women experience in midlife aren't just signs of getting older—but signals that…
- Extend Podcast with Darshan Shah, MD
210. Dr. Rena Malik: Why Erectile Dysfunction Could Be an Early Warning Sign of Heart Disease
What if problems in the bedroom were actually an early warning sign of something much bigger happening in your body? Most people think of sexual health as…
- Extend Podcast with Darshan Shah, MD
209. Dr. David Barzilai: Can We Reverse Aging? Harvard's Latest Longevity Science Explained
What if aging isn't just something that happens to us—but a biological process we can actually influence? For decades, medicine has focused on treating…
- Extend Podcast with Darshan Shah, MD
208. Dr. Thais Aliabadi: PCOS & Endometriosis—The Symptoms Women Should Never Ignore
What if the painful periods, irregular cycles, unexplained weight gain, acne, and fertility struggles so many women experience aren't something they should…
- Extend Podcast with Darshan Shah, MD
207. Dr. Jason Wersland: The Science of Recovery—Pain, HRV, Sleep & Your Nervous System
We spend so much time thinking about exercise, nutrition, and performance—but I believe recovery may be one of the most overlooked pieces of longevity. In this…
- Extend Podcast with Darshan Shah, MD
206. Dr. Pamela Smith: The Truth About Hormone Replacement Therapy—HRT, Menopause & Cancer Risk
Hormones influence far more than reproductive health. They affect your sleep, mood, metabolism, muscle, bone health, brain function, stress response, and how…
- Extend Podcast with Darshan Shah, MD
205. Rajeev Kapur: How AI Is Transforming Healthcare
What if AI could change the way we understand, manage, and optimize our health? In today's episode, my guest is Rajeev Kapur, a leading AI advisor, educator…
- Extend Podcast with Darshan Shah, MD
204. Dr. Cassie Smith: Fix Your Gut, Fix Your Hormones, Fix Your Health
What if your gut health is the missing piece behing your hormones, energy, metabolism, and how you feel every day? Today, I sit down with Dr. Cassie Smith, a…
- Extend Podcast with Darshan Shah, MD
203. Sat Randhawa: Can You Train Your Brain? QEEG & Neurofeedback
What if we stopped guessing about the brain and started measuring it? In today's episode, my guest is Sat Randhawa of One-Hype Wellness, where he and his team…
- Extend Podcast with Darshan Shah, MD
202. Dr. Colleen Cutcliffe: The Fiber-Gut Connection: How to Improve Your Microbiome, Blood Sugar & Cholesterol
Most people know they should eat more fiber. But what we're learning about fiber, gut health, and the microbiome goes far beyond digestion. Your gut contains…
- Extend Podcast with Darshan Shah, MD
201: Joey Munoz: The Truth About Nutrition, Protein, Weight Loss & Muscle
What if the biggest mistake you're making with your health isn't what you're eating - but the way you're thinking about nutrition in the first place? In this…
- Extend Podcast with Darshan Shah, MD
200. Dr. Will Cole: How to Heal Your Cells—Mitochondria, Peptides & the Science of Aging
What if the fatigue, brain fog, low energy, and other symptoms we associate with getting older actually begin much deeper—at the level of our cells? I've…
- Extend Podcast with Darshan Shah, MD
199. Dr. Jeffrey Wiegers: Stem Cells Explained—What They Can Do Now & What's Coming Next
What if medicine could do more than manage disease—and actually help the body repair itself? Regenerative medicine is moving quickly, but the world of stem…
- Extend Podcast with Darshan Shah, MD
198. Dr. Bryce Appelbaum: Your Eyes Are Connected to Everything—Focus, Balance, Brain Health & Aging
What if your eyesight is 20/20—but your vision still isn't working the way it should? Dr. Bryce Appelbaum specializes in functional vision and the connection…
- Extend Podcast with Darshan Shah, MD
197. Ben Greenfield: When Biohacking Goes Too Far—What Actually Matters for Longevity
What happens when optimizing your health starts taking over your life? Ben Greenfield has spent decades at the forefront of biohacking, fitness, human…
- Extend Podcast with Darshan Shah, MD
196: Dr. Jill Carnahan: Is Mold Making You Sick? Hidden Toxins, Symptoms & Detox
What if the fatigue, brain fog, inflammation, or unexplained symptoms you're experiencing aren't starting inside your body—but in the environment around you?…
- Extend Podcast with Darshan Shah, MD
195: Jeff Byers: Inside the Supplement Industry: The 4 Supplements That Actually Matter
Walk into any supplement aisle—or scroll through social media—and you'll find thousands of products promising better energy, performance, brain health, and…
- Extend Podcast with Darshan Shah, MD
194: Dr. Mark Hyman: Why You're Still Sick—Finding the Root Cause With Functional Medicine
What if the reason you're still sick isn't because there's no answer—but because no one has looked deeply enough for the root cause? My guest, Dr. Mark Hyman…
- Extend Podcast with Darshan Shah, MD
193: Dr. Sasha Hamdani: ADHD, Anxiety and How to Regulate your Emotions
What if ADHD isn't just an attention problem—but also a problem of emotional regulation? My guest, Dr. Sasha Hamdani, is a board-certified psychiatrist, ADHD…
- Extend Podcast with Darshan Shah, MD
192: Dr. Perlmutter: How to Protect Your Brain From Alzheimer's & Cognitive Decline
What if your risk of Alzheimer's isn't predetermined by your genes—but influenced by the metabolic health of your brain? My guest, Dr. David Perlmutter, is a…
- Extend Podcast with Darshan Shah, MD
191: Kiran Krishnan: How to Rebuild Your Gut Microbiome & Reduce Inflammation
What if the biggest mistake we're making with gut health is treating the microbiome like a list of bacteria instead of a living ecosystem? Your gut is home to…
- Extend Podcast with Darshan Shah, MD
190. Dr. William Harris: 90% of Americans Are Low in This Critical Longevity Nutrient
What if one of the most important markers for your heart, brain, and longevity is something most people have never measured? AND roughly 90% of Americans…
- Extend Podcast with Darshan Shah, MD
189. Dr. Florence Comite: The 5 Biomarkers That Predict How You'll Age
What if aging isn't something you simply accept - but something you can measure, predict, and even reverse? Most of us are told our lab work is "normal," yet…
- Extend Podcast with Darshan Shah, MD
188. James Beshara: How to Find Productivity Without the Hustle
We're living in a culture that celebrates being busy. More coffee. More hours. More hustle. But what if those things are actually making you less productive?…
- Extend Podcast with Darshan Shah, MD
187. Dr. Izabella Wentz: 30+ Root Causes Behind An IBS Diagnosis
Hashimotos isn't just a thyroid disease-it may actually begin in the gut. If you've been told your thyroid labs are "normal" but you still struggle with…
- Extend Podcast with Darshan Shah, MD
186. Raj Sisodia: The Inner Work Behind Better Leadership
A leader's unresolved pain rarely stays contained within that leader. It can show up as control, aggression, emotional distance, relentless pressure, or a…
- Extend Podcast with Darshan Shah, MD
185. Dr. Neha Sangwan: The 5 Questions That Predict a Health Crisis Before It Happens
I have operated on patients whose bodies had been sending them warning signals for years before a crisis ever put them in front of me. Stress alone causes or…
- Extend Podcast with Darshan Shah, MD
184. Dr. Sahil Chopra & Sagar Chopra: Why Your Sleep Apnea Machine Might Be Lying to You
Millions of people wear a CPAP machine every night, the standard breathing device prescribed for sleep apnea. They trust the number on the screen to tell them…
- Extend Podcast with Darshan Shah, MD
183. Rachel Lambert & Angie Noack: Why 70% Of ADHD Diagnoses Are Wrong
For most people, an ADHD diagnosis, an anxiety diagnosis, or a depression diagnosis is made entirely from a symptom checklist. No one looks at the brain…
- Extend Podcast with Darshan Shah, MD
182. Michael Easter: The Hidden Health Cost of Modern Comfort
A lot of people do not need to be convinced that the stairs are better than the escalator, walking is better than sitting all day, and reaching for the phone…
- Extend Podcast with Darshan Shah, MD
181. Dr. Taz: The Hormone Conversation Women Should Have Before Birth Control, IVF, or HRT
For many women, the hormone conversation starts only when something becomes hard to ignore. Painful periods. Irregular cycles. Acne. Hair loss. Fertility…
- Extend Podcast with Darshan Shah, MD
180. Dr. John Kim: The Hidden Stressors Keeping Your Body in Defense Mode
When labs look normal, it is easy to assume the body is fine or that the biggest risks have been ruled out. Dr. John Kim's story challenges that belief. At 33…
- Extend Podcast with Darshan Shah, MD
179. Dr. Scott McMahon: The Hidden Trigger Behind Your Unexplained Symptoms
Most people assume that once they leave a mold-exposed building, their body should recover. But I see this all the time in my clinic, the mold exposure ends…
- Extend Podcast with Darshan Shah, MD
178. Dr. Matt Kaeberlein: The Science, Risk, and Hype Behind Today's Longevity Trends
If you care about longevity, you have probably seen the same pattern over and over again. A new peptide, supplement, biological age test, off-label drug, or…
- Extend Podcast with Darshan Shah, MD
177. Dr. Jila Senemar: The Hormone Conversation Women Should Have Before Menopause
A lot of women are taught to think about hormones only when something becomes impossible to ignore. Painful periods. Birth control decisions. Fertility…
- Extend Podcast with Darshan Shah, MD
176. Dr. Labib Ghulmiyyah: What Fertility Can Reveal About Your Long-Term Health
When a couple is trying to get pregnant and it is not happening, the conversation can become very intense very quickly. Suddenly, you are hearing about IVF…
- Extend Podcast with Darshan Shah, MD
175. Justin Roethlingshoefer: Why Your Body Needs More Than "Healthy Habits" To Heal
Your body is constantly repairing, renewing, and rebuilding itself. Hundreds of millions of cells are replaced every few months, which sounds incredible until…
- Extend Podcast with Darshan Shah, MD
174. Dr. Dave Rabin: Why Being Human Feels Harder Than It Should in 2026
A lot of people are trying to do the right things. They are learning more, tracking their health, working on their stress, trying to be more present, and using…
- Extend Podcast with Darshan Shah, MD
173. Brian Le Gette: The Hidden Reason Your Body Struggles To Heal
When your body feels wired, depleted, foggy, inflamed, or slow to recover, the usual instinct is to add something else. Another supplement. Another device…
- Extend Podcast with Darshan Shah, MD
172. Dr. William Von Hippel: The Connection-Autonomy Paradox: Why More Freedom Can Make Us Feel More Alone
Modern life tells us that more freedom should make us happier. More independence, more control, more convenience, more space to do life on our own terms. But…
- Extend Podcast with Darshan Shah, MD
171. Dr. Kristen Holmes: The Sleep Debt Problem Affecting Your Brain, Mood, and Relationships
Sleep debt is usually treated like a personal problem. You sleep less, feel tired, and try to catch up later. But Dr. Kristen Holmes explains why that belief…
- Extend Podcast with Darshan Shah, MD
170. Dr. Sonya Jensen: The Hormone-Trauma Connection: Why Midlife Symptoms Are Not Just Physical
Hormone symptoms are usually treated like a problem with levels. Progesterone is low. Estrogen is shifting. Cortisol is high. Testosterone is dropping. So the…
- Extend Podcast with Darshan Shah, MD
169. Natalie Lefevre: How to Find the Toxins Blocking Your Body's Ability to Heal
You can do the supplements, the IVs, the sauna, the clean eating, and the wellness routine, but if your body is still being exposed to toxins every day, you…
- Extend Podcast with Darshan Shah, MD
168. Peter Crone: Why You Can't Access True Vitality Until You Free Your Mind
When we talk about health, longevity, and performance, the conversation often starts with the body. We look at biomarkers, sleep, nutrition, exercise…
- Extend Podcast with Darshan Shah, MD
167. Dr. Amie Hornaman: The Thyropause Problem: Why So Many Women Feel Off in Midlife Despite "Normal" Labs
Have you entered midlife and started gaining weight, feeling exhausted, waking up foggy, losing motivation, or noticing your mood shift while your labs keep…
- Extend Podcast with Darshan Shah, MD
166. Carolina Reis de Oliveira: The Missing Link Between Skin and Longevity
If you think your skincare routine is protecting your skin, this conversation may make you look at your bathroom shelf differently. You've been taught to treat…
- Extend Podcast with Darshan Shah, MD
165. Cynthia Thurlow: The Menopause Gut - Why Healing Your Hormones Starts With Healing Your Gut
The gut and hormones have always been treated as two completely separate conversations in medicine, and that disconnect is quietly behind some of the most…
- Extend Podcast with Darshan Shah, MD
164. SXSW Panel: How To Actually Take Control Of Your Health In 2026 and Beyond
A lot of us are doing everything we can to stay healthy, taking supplements, wearing trackers, getting our labs done, and still ending up sick. And if you are…
- Extend Podcast with Darshan Shah, MD
163. Steve Chua: How Your Identity Is Either Healing Or Destroying Your Health
Most high performing executives will spend thousands optimizing their glucose levels, their sleep, and their body composition without ever stopping to ask why…
- Extend Podcast with Darshan Shah, MD
162. Dr. Meredith Broderick: What An Undiagnosed Sleep Disorder Is Quietly Doing To Your Brain And Body
A lot of people are walking around exhausted, foggy, moody, and struggling with their cardiovascular health blaming stress, diet, age, and everything in…
- Extend Podcast with Darshan Shah, MD
161. McCall McPherson: Why Your Thyroid Is Being Undertested And Undertreated
Fatigue, brain fog, weight gain, hair loss, low libido, high cholesterol, and a doctor who keeps telling you your labs look normal. For the millions of people…
- Extend Podcast with Darshan Shah, MD
160. Dr. Kara Fitzgerald on Biological Age, Epigenetic Clocks, and the Future of Aging Reversal
Biological aging is no longer just a concept tied to time. It is something we can now measure, track, and influence through data, lifestyle, and targeted…
- Extend Podcast with Darshan Shah, MD
159: Dr. Anurag Singh: Urolithin A, Mitophagy, and Mitochondrial Health
Mitochondrial decline is one of the most overlooked drivers of aging, impacting energy, muscle function, cognitive performance, and immune resilience long…
- Extend Podcast with Darshan Shah, MD
158. Dr. Kavin Mistry: Primal Health Design, Biological Aging, and Reconnecting with Human Biology
Modern life is quietly accelerating biological aging, from posture and movement patterns to sleep disruption, chronic stress, and constant digital stimulation…
- Extend Podcast with Darshan Shah, MD
157. Dr. Tania Elliott: Allergies, Immune Health, and Hidden Toxins in Your Home
Allergies, chronic inflammation, and constant exposure to environmental toxins are reshaping how our immune system functions, often in ways that go unnoticed…
- Extend Podcast with Darshan Shah, MD
156. Dr. Judith Joseph: High-Functioning Depression, Anhedonia, and Reclaiming Joy
High-performing individuals often appear successful on the outside while quietly experiencing a loss of joy, emotional numbness, and chronic internal stress…
- Extend Podcast with Darshan Shah, MD
155. Dr. Eboni Cornish: Neural Longevity, Brain Inflammation, and the Hidden Root Causes of Mental Health Symptoms
Cognitive decline, mood disorders, and persistent neurological symptoms are often treated in isolation, even as underlying drivers like inflammation…
- Extend Podcast with Darshan Shah, MD
154. Dr. Rick Doblin - Part 2: Psychedelics, MDMA Therapy, and the Future of Mental Health
Mental health conditions like depression, PTSD, and trauma related disorders remain difficult to treat, especially when underlying cognitive and emotional…
- Extend Podcast with Darshan Shah, MD
153. Dr. Rick Doblin - Part 1: Psychedelics, MDMA Therapy, and the Future of Mental Health
Depression, PTSD, and trauma related disorders continue to challenge modern medicine, even as our understanding of the brain and consciousness rapidly evolves…