Shows / APOE4: Beat the Odds
APOE4: Beat the Odds
If you carry APOE4, you have probably heard plenty about risk and far less about what to do next. I am Kevin Tran, a Doctor of Pharmacy and the founder of The Phoenix Community. I carry APOE4/4. Each week, I turn research on Alzheimer's risk, biomarkers, nutrition, exercise, sleep, and emerging interventions into clear actions you can understand and discuss with your healthcare team. This podcast is for carriers and families who want evidence, context, and a practical way forward.
Episodes
- APOE4: Beat the Odds
APOE4: Should You Join a Prevention Trial? | Jessica Langbaum, PhD
Thinking about joining an Alzheimer's prevention trial as a healthy APOE4 carrier? Here's what it asks of you, and what to ask back. Jessica Langbaum, PhD, of…
APOE4: Beat the Odds400 APOE4 Patients on Rapamycin. Zero Got Dementia. (Doctor Explains)
Originally published on YouTube on 21 February 2026. Original video: https://www.youtube.com/watch?v=z7rxmVLAMT0 Free guide: The APOE4 Emerging Therapies…
APOE4: Beat the OddsThe NAD+ Breakthrough Every APOE4 Carrier Must Know (And a Warning about Your Supplements)
Originally published on YouTube on 1 March 2026. Original video: https://www.youtube.com/watch?v=-uu0L2Y-PlI Free guide: The APOE4 Supplement Guide…
APOE4: Beat the OddsKetosis and APOE4: Why Generic Keto Fails (And What Actually Works)
Originally published on YouTube on 17 February 2026. Original video: https://www.youtube.com/watch?v=ayi3qDYeYvo Free guide: The APOE4 Metabolic Guide…
- APOE4: Beat the Odds
Two Copies of APOE4: What Should You Do Next? | Dr. Gayatri Devi
Two copies of APOE4. Does every memory lapse mean something, and would more testing help? Dr. Gayatri Devi explains why she starts with a cognitive baseline…
APOE4: Beat the OddsZone 2 Training for APOE4: Your Exact Heart Rate Targets For Maximum Brain Health
Originally published on YouTube on 25 February 2026. Original video: https://www.youtube.com/watch?v=XnRBrxA0Z_U Free guide: The APOE4 Exercise Protocol…
APOE4: Beat the OddsAPOE4 & Meat: What the JAMA Study Actually Says (And What Everyone Gets Wrong)
Originally published on YouTube on 15 April 2026. Original video: https://www.youtube.com/watch?v=Xoq4DTX_YtM Free guide: The APOE4 Diet Playbook…
APOE4: Beat the OddsHRT + APOE4: What the Research Actually Shows (Men & Women)
Originally published on YouTube on 27 April 2026. Original video: https://www.youtube.com/watch?v=oY_R_VOiwys Free guide: The APOE4 Woman's Guide…
- APOE4: Beat the Odds
The APOE4 Overwhelm No One Warns You About
Originally published on YouTube on 2 June 2026. Original video: https://www.youtube.com/watch?v=-H5sUDXghD4 You're not failing. You're overwhelmed. In this…
APOE4: Beat the OddsHow Ezetimibe Took My ApoB Down Nearly 40% (APOE4/4, No Statin)
Originally published on YouTube on 9 June 2026. Original video: https://www.youtube.com/watch?v=wbDdVGjvdFc Using diet, psyllium husk and ezetimibe, I lowered…
APOE4: Beat the OddsWhy APOE4 Carriers MUST Fix Their Sleep (And Exactly How)
Originally published on YouTube on 6 June 2026. Original video: https://www.youtube.com/watch?v=V72QViR99hk Why does sleep matter so much for APOE4 carriers? I…
APOE4: Beat the OddsWhy Fish Oil Fails Your APOE4 Brain (And What Actually Works)
Originally published on YouTube on 1 July 2026. Original video: https://www.youtube.com/watch?v=oYAvOrTa1MQ What's the best omega-3 for the APOE4 brain, and…
APOE4: Beat the OddsAPOE4: When Is It Too Late To Prevent Alzheimer's?
Originally published on YouTube on 22 June 2026. Original video: https://www.youtube.com/watch?v=00FQv25sZD4 If you carry APOE4 and watched a parent decline…
APOE4: Beat the OddsOptimizing Hormones for APOE4 Brain Health: Vitamin D, HRT, Testosterone & Thyroid
Originally published on YouTube on 18 June 2026. Original video: https://www.youtube.com/watch?v=JEZMcgyEm68 Vitamin D, estrogen, testosterone and thyroid…
APOE4: Beat the OddsAPOE4 and brain stress: why your hs-CRP, ferritin, and iron need a different lens
Originally published on YouTube on 15 June 2026. Original video: https://www.youtube.com/watch?v=TFQ-pN0OqOM Your hs-CRP looks normal. What does that mean…
APOE4: Beat the OddsAPOE4 Biomarkers Pt.1: Omega 3 and Homocysteine - Why Your "Normal" Labs Results Might Be Lying
Originally published on YouTube on 10 May 2026. Original video: https://www.youtube.com/watch?v=DM2JSshVf-E The normal lab ranges were built for the general…
APOE4: Beat the OddsAPOE4: Your Brain Is Insulin Resistant (Even If Your Labs Are Normal)
Originally published on YouTube on 5 April 2026. Original video: https://www.youtube.com/watch?v=PBL1HS8w58E Your blood sugar looks fine. Your A1C is normal…
APOE4: Beat the OddsAPOE4 & Lipids: Why Your Doctor's Targets Aren't Aggressive Enough (Statin Debate Settled?)
Originally published on YouTube on 21 March 2026. Original video: https://www.youtube.com/watch?v=btrclmF2SE0 Your standard lipid panel isn't built for APOE4…
APOE4: Beat the OddsAPOE4 Carriers: This Common Shot May Cut Dementia Risk
Originally published on YouTube on 5 August 2026. Original video: https://www.youtube.com/watch?v=yMWdfTwbRS8 A shingles vaccination program in Wales became a…
APOE4: Beat the OddsHearing Loss and APOE4: The Dementia Risk Nobody Checks
Originally published on YouTube on 27 July 2026. Original video: https://www.youtube.com/watch?v=KEfFx-m_Ppc Hearing loss is easy to overlook when you're…
APOE4: Beat the OddsThe Blood Pressure Number That Cuts Dementia Risk | Dr. Jeremy Pruzin, MD
Originally published on YouTube on 14 September 2026. Original video: https://www.youtube.com/watch?v=mkUqj8Crzbg Half of this community asked me the opposite…
APOE4: Beat the OddsDoes Creatine Help the APOE4 Brain? What the Clinical Trials Show
Originally published on YouTube on 25 August 2026. Original video: https://www.youtube.com/watch?v=kBEE0VZXWfM Creatine for APOE4 carriers: can a $15…
APOE4: Beat the OddsIs It Ever Too Late for HRT? Timing, Tests and What to Ask Your Doctor
Originally published on YouTube on 3 September 2026. Original video: https://www.youtube.com/watch?v=oCSbRP03j3U Your birthday doesn’t decide whether you start…
APOE4: Beat the OddsMenopause, What HRT Actually Does & What It Means for APOE4 Carriers
Originally published on YouTube on 13 August 2026. Original video: https://www.youtube.com/watch?v=OJV7O5hnKos One 2002 study shaped how millions of women…
APOE4: Beat the OddsBoth Parents Died of Alzheimer's. Now this Physician is Fighting Back. | Phoenix Member Stories
John lost both his parents to Alzheimer's. His mom. Then his dad. He retired early to care for his father, watched the disease take everything, and then got…
APOE4: Beat the OddsShe Diagnosed Her Mother With Alzheimer's. Then Found Out She Carries the APOE4 Gene.
Dr. Gertrude Behan spent decades as a family medicine physician in Australia. She diagnosed patients with Alzheimer's. She saw firsthand how little the…
APOE4: Beat the OddsEx-Intelligence Analyst's APOE4 Protocol (After 13 Years)
She spent 30 years as an intelligence analyst — investigating biological weapons, briefing senators, training a generation of researchers. Then she found out…
APOE4: Beat the Odds72 and Cognitively Sharp: How This APOE4/4 Carrier Beat the Odds | Donna's Story
Donna found out she carried two copies of the APOE4 gene (APOE4/4) almost 10 years ago during a research study at Yale. She was 62. Nobody was talking about…
APOE4: Beat the OddsAPOE4/4 and in the Best Shape of Her Life at 55. Here's What Changed.
She found out she was APOE4/4 on her anniversary in Hawaii. In the shower. She collapsed crying. Then she opened her laptop and started searching. That was…