Shows / This Week in Startups

This Week in Startups
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world's greatest founders, operators, investors, and innovators.
Episodes
This Week in StartupsDid the Midterms Destroy All Hope for Data Centers? | E2360
This Week In Startups is made possible by: Odoo: https://Odoo.com/twist Sentry: https://sentry.io/twist Stripe: https://stripe.com/startups Plaud…
This Week in StartupsWhy a Do-Nothing Congress could be great for markets | E2359
This Week In Startups is made possible by: Every: https://every.io/ Vanta: https://www.vanta.com/twist G2i: https://g2i.co/twist Plaud: https://plaud.ai/twist…
This Week in StartupsOdyssey CEO Oliver Cameron is 90% sure we live in a simulation | E2358
This Week In Startups is made possible by: Paper: https://getpaper.ai/twist G2i: https://G2i.co/twist Northwest Registered Agent…
This Week in StartupsBinance Hacked $6.3B Stolen, DoorDash Buys Instacart For $17B, Jake Newfield from Hermetiq, + More!
This Week In Startups is made possible by: Stripe: https://stripe.com/startups Rippling: https://rippling.ai/twist Northwest Registered Agent…
This Week in StartupsIs AI the new cigarettes? Our VC panel digs into Anthropic’s S-1 | E2356
This Week In Startups is made possible by: PayPal: https://paypal.com/business The Conservation Fund: https://www.conservationfund.org/ Hostinger…
This Week in StartupsPregame Your Launch Before Your App Exists (w/ Amanda Bradford) | E2355
This Week In Startups is made possible by: Odoo: https://odoo.com/twist G2i: https://g2i.co/twist Rippling: https://rippling.ai/twist Plaud…
This Week in StartupsOpenAI’s $1.25T Raise, Starlink Mobile & Zuck’s Tax Deal | EP 2354
This Week In Startups is made possible by: Plaud - https://plaud.ai/twist Sentry - https://sentry.io/twist Lightfield - https://lightfield.app Rippling -…
This Week in StartupsWe asked 3 VCs: would you invest in Elizabeth Holmes’ next startup? | E2353
This Week In Startups is made possible by: DigitalOcean - Head to https://do.co/twist to start building on DigitalOcean's AI-Native Cloud today — and cut your…
This Week in StartupsAnthropic Gives Away 5% of Its Shares, Clone’s Muscle Robot, ElevenLabs Steals Podcaster's Voice
This Week In Startups is made possible by: Plaud: https://plaud.ai/twist Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain…
This Week in StartupsFlying Cars, OpenAI Spies, Why AI Isn’t Sticking (Superhuman CEO)
This Week In Startups is made possible by: Lightfield: https://lightfield.app Every.io: https://every.io/ PayPal: https://paypal.com/business Plaud…
This Week in StartupsThe Ex-DeepMind Researcher Taking On China’s Open Source AI
This Week In Startups is made possible by: Paper: https://getpaper.ai/twist Superhuman: https://superhuman.com/ Odoo: https://Odoo.com/twist Today’s show…
This Week in StartupsThe Gadget That's Better in Crowds Than Your Phone + Ring’s Founder Before Amazon Bought It | E2349
This Week In Startups is made possible by: Plaud: https://plaud.ai/twist Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain…
This Week in StartupsJason Reacts To Japanese Founder Pitches + Fireside Chat With Yuki Shirato
This Week In Startups is made possible by: Lightfield: https://lightfield.app Rippling: https://Rippling.ai/twist Upwork: https://upwork.com Today’s show…
This Week in StartupsWhat VCs Really Think About Personal AI Agents | E2347
This Week In Startups is made possible by: Plaud: https://plaud.ai/twist Odoo: https://odoo.com/twist Northwest Registered Agent…
This Week in StartupsJason Mentors The Next Generation + Why AI Is Bad at Teaching (Aristotle Interview) | E2346
This Week In Startups is made possible by: Vanta: https://www.vanta.com/twist DigitalOcean: https://do.co/twist Sentry: https://sentry.io/twist Plaud…
This Week in StartupsInside The Startup Building Uncensored AI (Abliteration AI) | EP 2345
This Week In Startups is made possible by: Every.io: https://every.io/ Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Odoo…
This Week in StartupsJustin Kan & Brian Chesky: The Rejections That Built Twitch and Airbnb | E2344
This Week In Startups is made possible by: Plaud: https://plaud.ai/twist CLA: https://www.claconnect.com/withyou Sentry: https://sentry.io/twist Lightfield…
This Week in StartupsJason’s Put a $5K Bounty on His Dream Chrome Extension | E2338
This Week In Startups is made possible by: Every.io: https://every.io/ Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Sentry…
This Week in StartupsThe 5 Companies Apple Must Buy
This Week In Startups is made possible by: PayPal: https://paypal.com/business Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain…
This Week in StartupsA rogue OpenAI agent hacked Australia’s government. Does this matter? | E2342
This Week In Startups is made possible by: Lightfield: https://lightfield.app Paper: https://getpaper.ai/twist The Conservation Fund…
This Week in StartupsVCs Would Bet on Open-Source AI Over OpenAI and Anthropic | E2341
This Week In Startups is made possible by: Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Odoo: https://odoo.com/twist…
This Week in StartupsElon's New Hyperloop, Trump's AI Rename, and a Model That Won't Talk | E2340
This Week In Startups is made possible by: Vanta: https://www.vanta.com/twist DigitalOcean: https://do.co/twist Lightfield: https://lightfield.app Plaud…
This Week in StartupsHugging Face Co-Founder on Open-Source, Microduck, and NVIDIA | E2339
This Week In Startups is made possible by: Superhuman: https://superhuman.com/ Paypal: https://paypal.com/business Odoo: https://odoo.com/twist Plaud…
This Week in Startups90% of AI prototypes never reach production (w/ Temporal's Samar Abbas) | AI Basics
The TWiST AI Basics series is made possible by Google for Startups! Build context-aware AI workflows using DeepMind models and orchestration tools with Google…
This Week in StartupsAsk Jason: AI Extinction, Grok's Rogue Meme Coin & Weed Farms as Data Centers | E2337
This Week In Startups is made possible by: Quo: http://quo.com/TWiST The Conservation Fund: https://conservationfund.org CLA…
This Week in StartupsThe Pentagon Wants Equity in AI Startups | E2336
This Week In Startups is made possible by: DigitalOcean: https://do.co/twist Odoo: https://odoo.com/twist Upwork: https://upwork.com Today's show: The Pentagon…
This Week in StartupsBecki DeGraw on founder vesting, advisor equity & the 4-term-sheet play
This Week In Startups is made possible by: Wilson Sonsini: https://www.wsgr.com/en/ Today's show: One of YouTube's three co-founders left for grad school and…
This Week in StartupsDid OpenAI Steal the Navier-Stokes Solution? | E2335
This Week In Startups is made possible by: Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain NetSuite…
This Week in StartupsDr. Mark Hyman on Function Health & GLP-1 microdosing | E2334
This Week In Startups is made possible by: Odoo: https://odoo.com/twist Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain…
This Week in StartupsBecki DeGraw on spinouts, IP licensing & clean exits | Wilson Sonsini Startup Legal Basics
This Week In Startups is made possible by: Wilson Sonsini Today's show: Spinouts are everywhere right now, and most founders get the cap table wrong. Jason…
This Week in StartupsVC experts on why Physical AI funding is heating up | E2333
VC experts on why Physical AI funding is heating up | E2333 This Week In Startups is made possible by: partner 1 - link partner 2 - link partner 3 - link…
This Week in StartupsAre AI Agents forming "civilizations" or is this just a psy op? | 2332
This Week In Startups is made possible by: Northwest Registered Agent: https://northwestregisteredagent.com/twistdomain CLA: https://www.claconnect.com/withyou…
This Week in StartupsBreaking down Nvidia's Hugging Face and Poolside bets | E2331
This Week In Startups is made possible by: DigitalOcean: https://do.co/twist Every.io: https://every.io PayPal: https://paypal.com/business Today's show…
This Week in StartupsBill Gates foresees massive AI job loss: these VCs disagree | E2330
This Week In Startups is made possible by: Lightfield: https://lightfield.app Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain…
This Week in StartupsYou Can't Fire a VC From Your Board: Here's Why | Wilson Sonsini Startup Legal Basics
Today's show: Can a founder actually fire a board member? Short answer: almost never. And the reason why may surprise a lot of founders. On this edition of…
This Week in StartupsChina wants you to cheer for the robots taking your job | E2329
This Week In Startups is made possible by: Odoo: https://odoo.com/twist Quo: https://quo.com/TWiST Conservation Fund: https://conservationfund.org/ how old a…
This Week in StartupsOpen source is going to win it all: Harvey proves it | E2328
This Week In Startups is made possible by: Superhuman: https://superhuman.com Sentry: https://sentry.io/twist Lightfield: https://lightfield.app Today's show…
This Week in StartupsTaste is the new programming language (w/ Astrocade CEO Amir Sadeghian) | AI Basics
The TWiST AI Basics series is made possible by Google Cloud! Build context-aware AI workflows using DeepMind models and orchestration tools with Google for…
This Week in StartupsNeurosymbolic AI outperforms chatbots and product search | E2327
This Week In Startups is made possible by: Vanta: https://www.vanta.com/twist Agree: https://agree.com YSecurity: https://ysecurity.io/TWIST Today's show…
This Week in StartupsBittensor creator Const on Affine, dTAO, "mining reasoning," and more | E2326
This Week In Startups is made possible by: Northwest Registered Agent: https://northwestregisteredagent.com/twist DigitalOcean: https://do.co/twist Odoo…
This Week in StartupsWhat we'll learn from Anthropic's $2-$3T IPO | E2325
This Week In Startups is made possible by: PayPal Open https://paypal.launch.co CLA https://claconnect.com/withyou Odoo https://Odoo.com/twist Today's show…
This Week in StartupsThese robots could cut delivery costs by 80% | Next Unicorns
These robots could cut delivery costs by 80% | Next Unicorns This Week In Startups is made possible by: Squarespace https://squarespace.com/twist Northwest…
This Week in StartupsZuck's AI manifesto is a data center PR masterclass | E2323
This Week In Startups is made possible by: Every.io https://every.io NetSuite https://NetSuite.ai/TWIST YSecurity https://YSecurity.io/TWIST Today's show…
This Week in StartupsHow AI splits startups into winners and losers | E2322
This Week In Startups is made possible by: DigitalOcean https://do.co/twist Sentry https://sentry.io/twist Lightfield https://lightfield.app Today's show: A…
This Week in StartupsAirtable's 80% off value crash: VCs explain why it's still a win | E2321
This Week In Startups is made possible by: Vanta https://www.vanta.com/twist Agree https://agree.com Odoo https://Odoo.com/twist Today's show: *Airtable just…
This Week in StartupsHow Bespoke faked AI until it actually worked (w/ Akemi Tsunagawa) | E2320
This Week In Startups is made possible by: Odoo https://Odoo.com/twist Quo https://quo.com/TWiST Northwest Registered Agent…
This Week in StartupsWhy AI has no taste and how to fix it (w/ Thais Castello Branco) | E2319
This Week In Startups is made possible by: YSecurity https://YSecurity.io/TWIST MongoDB https://MongoDB.com/ai Odoo https://Odoo.com/twist Today's show: AI…
This Week in StartupsBanning Chinese robots isn't regulatory capture | E2318
This Week In Startups is made possible by: Northwest Registered Agent- NorthwestRegisteredAgent.com/twist Odoo - Odoo.com/twist MongoDB - MongoDB.com/ai…
This Week in StartupsWhile other cultivated meat companies are collapsing, this one turned a profit | E2317
This Week In Startups is made possible by: Every.io https://every.io MongoDB https://MongoDB.com/ai Agree https://agree.com Today's show: *Most lab-grown meat…
This Week in StartupsWhy quantum has been "10 years away" for 30 years | E2316
This Week In Startups is made possible by: PayPal Open https://paypalopen.com DigitalOcean https://do.co/twist Rippling https://Rippling.ai/twist Today's show…
This Week in StartupsWhy this longevity startup raised in Japan, not Silicon Valley | TWiST Tokyo | E2315
This Week In Startups is made possible by: Sentry https://sentry.io/twist Agree https://agree.com Northwest Registered Agent…
This Week in StartupsThe AI Securing Your Workforce Before a Mistake Ever Becomes a Breach | E2314
This Week In Startups is made possible by: Vanta https://www.vanta.com/twist Superhuman https://superhuman.com YSecurity https://YSecurity.io/TWIST Today's…
This Week in StartupsThe dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313
The dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313 This Week In Startups is made possible by: Northwest Registered Agent…
This Week in StartupsA Startup Is Trying to Buy PayPal… Craziest Deal of 2026! | E2312
This Week In Startups is made possible by: MongoDB - MongoDB.com/ai Rippling - Rippling.ai/twist Agree.com - agree.com Today's show: Hustle Fund's Eric Bahn…
This Week in StartupsJason turned $11 and one tweet into 1.1M views | E2311
This Week In Startups is made possible by: Quo https://quo.com/TWiST PayPal Open https://paypalopen.com Northwest Registered Agent…
This Week in StartupsDanny Bernstein left Big Tech to fund farm-bots | E2310
This Week In Startups is made possible by: NetSuite https://NetSuite.ai/TWIST Squarespace https://squarespace.com/twist YSecurity https://YSecurity.io/TWIST…
This Week in StartupsWhy Data Is the Next $1 Trillion Market
This Week In Startups is made possible by: Digital Ocean - do.co/twist Agree.com - agree.com Every.io - every.io. Today's show: How many startups matter in…
This Week in Startups$100T is managed by "human duct tape" | E2308
This Week In Startups is made possible by: Northwest Registered Agent https://northwestregisteredagent.com/twist Vanta https://www.vanta.com/twist Sentry…
This Week in StartupsWhy the VC Hype Cycle Always Gets It Wrong | VC Roundtable | E2307
This Week In Startups is made possible by: CLA - www.claconnect.com/withyou Northwest Registered Agent - www.northwestregisteredagent.com/twist Agree.com -…
This Week in StartupsChamath on why young people need more agency, risk, and adventure
This Week In Startups is made possible by: Plaud https://Plaud.ai/twist Shopify https://shopify.com/twist LinkedIn Jobs https://LinkedIn.com/twist Northwest…