Shows / The a16z Show
The a16z Show
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
Episodes
The a16z ShowAlex Honnold on Human Performance (part 2) – Climbing and Entrepreneurship
In part 1 of our series on human performance, we looked at the limits of human potential in climbing and other sports – and how we push those limits through…
The a16z ShowAlex Honnold on Human Performance (part 1) – Where's the Limit?
Is there a limit to what humans can do? And if so, how do you know when you've reached it? Welcome to part one of a two-part series on human performance with…
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Why We Shouldn’t Fear AI in Healthcare
"Why We Shouldn’t Fear the ‘Black Box’ of AI (in Healthcare and Everywhere)" by Vijay Pande. First published in the New York Times, January 2018. You can also…
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When One App Rules Them All: The Case of WeChat and Mobile in China
"When One App Rules Them All: The Case of WeChat and Mobile in China" by Connie Chan. First published August 2015. You can also find and share this essay at…
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Every Company Is a Fintech Company
"Why Every Company Will Be a Fintech Company -- The Next Era of Financial Services and the 'AWS Phase' for Fintech" by Angela Strange. You can also find and…
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Read-Alouds, Continued
Today we're continuing a series we started a while ago of read-alouds (for more context on the why and why now check out episode #500 on how we podcast!). The…
The a16z ShowJournal Club: Revisiting Eroom's Law
Eroom’s Law is Moore’s Law spelled backwards. It’s a term that was coined in a Nature Reviews Drug Discovery article by researchers at Sanford Bernstein and…
The a16z ShowPreventing Pandemics with Genomic Epidemiology
The COVID-19 pandemic has increased the visibility of scientists and the scientific process to the broader public; suddenly, scientists working on virology and…
The a16z ShowJournal Club: Therapeutic Video Game on Trial
In this episode of the a16z bio journal club, we cover one of the key clinical trials that supported the recent FDA approval of the first prescription video…
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Gross Margins, Early to Late: What They Do (and Don't) Tell You
Gross margins are essentially a company's revenue from products and services minus the costs to deliver those products and services to customers, and it's one…
The a16z ShowBuilding Products for Power Users
As more digital natives have entered the workplace, they have brought with them the expectation that their software should both be a joy to use and allow them…
The a16z ShowJournal Club: Building a Better Chloroplast
In this episode of the a16z bio Journal Club, bio deal team partner Judy Savitskaya and Lauren Richardson discuss research that aims to enhance the efficiency…
The a16z ShowReal Estate in a Pandemic: Renters and Landlords (Part 2)
This episode is the second in a two-part series that examines the pandemic’s impact on real estate. Part 1 focused on prospective home buyers, sellers, and…
The a16z ShowReal Estate in a Pandemic: Homeowners and Buyers (Part 1)
This episode is the first in a two-part series that examines the pandemic’s impact on real estate. Part 1 focuses on prospective home buyers, sellers, and…
The a16z ShowWorld’s Largest Supercomputer v. Biology’s Toughest Problems
Proteins are molecular machines that must first assemble themselves to function. But how does a protein, which is produced as a linear string of amino acids…
The a16z ShowThe Return of Home-based Healthcare
The way we deliver healthcare has changed enormously over the last century, shifting from house calls by doctors to your own to institutionalized settings like…
The a16z ShowThe Future of Primary Care
Primary care was meant to be the front door to the healthcare system, but in some ways never set up for success to begin with. We need a new operating system…
The a16z ShowAll about Section 230: What It Does and Doesn't Say
We cover the tricky but important topic of Section 230 of the Communications Decency Act. The 1996 law has been in the headlines a lot recently, in the context…
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What We Can't Reveal We Can't Heal
Given recent events around George Floyd and far beyond, this special episode of the a16z Podcast features Shaka Senghor, a leading advocate for criminal…
The a16z ShowSaaS Go-to-Upmarket
For a SaaS company, it's easier to move upmarket than down, and this gives SaaS startups the advantage against incumbents. In this episode, David Ulevitch and…
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New Fan Engagement Models for Athletes and Influencers
Today’s episode is about a practical application of crypto — namely, the way it can “tokenize” fandom. More broadly, it’s about fan engagement, and the…
The a16z ShowDon't Call it a Brain in a Dish!
Our understanding of the human brain and its disorders has always been limited by our lack of access to living, human, developing brain tissue. For the first…
The a16z ShowPandemics: Early Detection, Networks, Spreaders
Pandemics are predictable; what's not predictable is the intensity, or the precise timing of arrival. That's where early detection -- not just rapid warning…
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Podcasting and the Future of Audio
This podcast (first recorded in 2019, now being rerun) -- is a podcast about podcasting: But it's really all about audio. A lot's changed... and a lot hasn't…
The a16z ShowGrowth in Turbulent Times
In normal times, every company operates against some hypothetical growth model—a data-driven framework that describes how your product grows and how you…
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Journal Club: Using CRISPR to Prevent Coronavirus and Influenza Infection
In this episode of a16z bio Journal Club, general partner Vijay Pande, bio deal team partner Andy Tran, and bio editor Lauren Richardson discuss a novel…
The a16z ShowWhat's Next in Gaming
Video game technology has evolved into a global phenomenon that extends far beyond entertainment. In this episode, John Riccitiello, CEO of the game software…
The a16z ShowUndruggable Drugs
In this episode of the a16z Podcast, we take a deep dive into the world of drug development—specifically "undruggable drugs": a category of protein, protein…
The a16z ShowThe Next Generation of Cultural Influencers in Tech
This episode—which originally took place as a live event—is a conversation between Seattle Seahawks linebacker Bobby Wagner and a16z Cultural Leadership Fund…
The a16z ShowThe Chief Security Officer in (and out of) a Crisis
The Chief Security Officer (CSO/CISO) used to manage on-premise servers, now the information they have to secure has migrated to the cloud. As the…
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Journal Club: Finding New Antibiotics with Machine Learning, What Coronavirus Structures Tell Us
a16z Journal Club (part of the a16z Podcast), curates and covers recent advances from the scientific literature -- what papers we’re reading, and why they…
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Introducing Journal Club
Announcing a16z Journal Club, a new show where we curate and discuss recent research papers with a16z experts and others. This new show continues the a16z…
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What the Narrow Waist of the Internet Means for Innovation Today
Here is Ali's tweetstorm on the Narrow Waist of Blockchain Computing Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to…
The a16z ShowIT'S TIME TO BUILD
“It's Time to Build” by Marc Andreessen. You can also find and share this essay at a16z.com/build Stay Updated: Find a16z on YouTube: YouTube Find a16z on X…
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Introducing Read Alouds
We wanted to let you know about a special new series of posts occasionally read out loud from us (you can learn more about the why and why now in episode #500…
The a16z ShowThe Passion Economy: Redefining Work
This episode of the a16z Podcast covers the the rise of online platforms that enable people to make a living off their unique interests and skills. It's a…
The a16z ShowWhen Bad Policy = Bad Business Models = Bad Public Health
with @JorgeCondeBio, @julesyoo, and @omnivorousread In some ways, the coronavirus feels like it came out of nowhere—a kind of Black Swan event. But at the same…
The a16z ShowMoving to Remote Development (and Work)
From agile project management to asynchronous collaboration, development teams have pioneered many of the tools and best practices for remote work. However…
The a16z ShowVirtual Oncology
with @vintweeta @pbcancerdoc @sumitshahmd @omnivorousread Coronavirus is now disrupting the entire health care system, not just because of the burden of…
The a16z ShowThe Story of Schizophrenia
Descriptions of the mental illness we today call schizophrenia are as old as humankind itself. And more than likely, we are are all familiar with this disease…
The a16z ShowNavigating the Numbers
For any business, there are three core financial statements – the income or P&L statement, the balance sheet, and the cash flow statement. While these…
The a16z ShowGaming and Livestreaming: Connecting While Distancing
Since social distancing measures were first put in place, time spent gaming has gone up—way up. According to a recent report by Verizon, video game usage in…
The a16z ShowThe Hustlers's Guide to Suing the Man
This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for people…
The a16z ShowThe Hustler's Guide to Elder Care
This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for people…
The a16z ShowThe Hustler's Guide to Nursing Jobs
This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for people…
The a16z ShowHustlin' Tech, Round Two
This is the next cycle of Hustlin' Tech -- a podcast series co-hosted by bestselling authors, a16z co-founder Ben Horowitz; and Shaka Senghor, a leading voice…
The a16z ShowSecurity When the Workforce Goes Remote
We are in the midst of a rapid and unprecedented shift to remote work. What does it mean for security when the airgap between work and life is gone? How…
The a16z ShowThe Delivery-Optimized Future of Food
The spike in online ordering and food delivery—a trend that's particularly relevant now—is evidence of how tech is fundamentally changing how and what we eat…
The a16z ShowRemote Work and Our New Reality
Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts…
The a16z ShowWhen Medicine Goes Virtual
We’re at a moment where we are now seeing medicine go virtual faster, and at a scale that it has never done before. In this conversation, a16z bio general…
The a16z ShowLabs for Diagnostics: Then, Now, and Next
A lot's going on in the world of healthcare right now, and one topic that's especially relevant is how diagnostic labs work. In this episode with Dave King…
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How a16z's Crypto Startup School Went Remote
On February 21, Andreessen Horowitz kicked off its very first Crypto Startup School, with 45 students from around the U.S. and three countries gathering to…
The a16z ShowWhen Fintech Meets Social
The last financial crisis prompted many consumers to reassess their banking expectations—none more so than millennials and Gen-Z-ers. While revealing one's…
The a16z ShowInnovation Through Software Development and IT
One of the recurring themes we talk about a lot on the a16z Podcast is how software changes organizations, and vice versa... More broadly: it’s really about…
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The Open Source CIO
In 2014, in "Why There Will Never Be Another Red Hat," Peter Levine argued that Red Hat’s open source business model of commercializing support and services…
The a16z ShowNovel Coronavirus Updates: How Healthcare System, Tests Work; More
This episode covers the following -- since our previous deep-dive on the novel coronavirus outbreak -- including: practical implications for the U.S…
The a16z ShowMetrics and Mindsets for Retention & Engagement
It's "Marketplaces Week" for us at a16z, thanks to our consumer team releasing a new index of the next industry-defining marketplaces, the Marketplace 100. But…
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Tough Love, Global Diplomacy, and Lessons on Leadership
Susan shares how she learned to leverage the characteristics of her personality early in her career as assistant secretary of state [2:05] One of the important…
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Building the First CAR T Company
with @OzAzamTmunity1, @JorgeCondeBio, and @omnivorousread CAR T therapy, the groundbreaking new medicines that uses engineered T-cells to attack cancer, has…
The a16z ShowRebel Talent
When we think about rebellious behavior in the context of organizations and companies, we tend to think of rebels as trouble-makers, rabble-rousers; in other…