Shows / The a16z Show

The a16z Show
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
Episodes
The a16z ShowUncontrolled Spread: Science, Policy, Institutions, Infrastructure
There's no question technology played a huge role in the recent/current pandemic, including especially in the plug-and-play engineering and incredibly fast…
The a16z ShowSystems Leadership for Disruptors and Incumbents
There's been a false dichotomy in technology and management lore over the past decade, between "brain" and "brawn", digital and physical, independence and…
The a16z ShowNFT Use Cases, Today and Tomorrow
Recently, a16z and the Stanford Center for Blockchain Research hosted the NFT Virtual Summit, which brought together leading thinkers and builders on the topic…
The a16z ShowMan, Mosquito, Malaria Vaccine
Playing out against the backdrop of a global pandemic (including recent massive surges in regions around the world) is the news that came out a week ago that a…
The a16z ShowCrypto, an Oral Essay
This is a special episode of the a16z podcast — it's an audio history, told through the voices of the a16z crypto team, about what crypto is, how it really…
The a16z ShowOn Monetizing Community with Patreon Cofounder Sam Yam
It's clear from the growth of Patreon, Substack, TikTok, Clubhouse and many more that the power of the Creator Economy continues to build. These platforms…
The a16z ShowThe Creator Economy: NFTs and Beyond
In today’s episode of the a16z Podcast, we’re talking about the Creator Economy, and how NFTs (but not just NFTS!) are making it possible for artists…
The a16z ShowAll about NFTs
This episode is all about NFTs. It seems like nothing has caught on and spread into mainstream interest like NFTs, where one hears everything from "I've never…
The a16z ShowThe Next Wave of Marketplace Startups
In the tech world, marketplaces are a hot topic. That term—marketplace—encompasses a huge swath of services we use every day, from grocery delivery to online…
The a16z ShowThe Third Vaccine, and Vaccine Choice
https://a16z.com/2021/03/15/16-minutes-58-the-johnson-johnson-vaccine-and-covid-efficacy-rates/ Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find…
The a16z ShowCompanies & Culture: What You Do Is Who You Are
This podcast -- which was recorded at the Computer History Museum in a live event, before the pandemic (first published in December 2019) is all about how…
The a16z ShowBoss Talk with Ben Horowitz
Boss Talk is a weekly live show on Clubhouse, where a16z cofounder Ben Horowitz and Databricks CEO Ali Ghodsi discuss CEO stuff, leadership stuff, management…
The a16z ShowAll About Ransomware
In just the last couple years, ransomware has grown into a multibillion dollar industry. It has evolved from taking systems and servers hostage to stealing…
The a16z ShowOne on One with Marc and Ben
On social audio app Clubhouse, Marc Andreessen and Ben Horowitz are hosting a new live show called "One on One with A and Z", where they go deep on questions…
The a16z ShowAmazon Narratives: Memos, Working Backwards from Release, More
When you hear stories about Amazon's "invention machine" -- which led to a company with not just one or two products but several successful diverse lines of…
The a16z ShowAnatomy of the SolarWinds Hack: Who What Where When How
In this special “3x”-long episode of our (otherwise shortform) news analysis show 16 Minutes -- past such 2-3X explainer episodes have covered section 230…
The a16z ShowPsychedelics: Striking a Balance Between Benefits and Side Effects
In recent years, there’s been a shift in how we think about psychedelics – from drugs of abuse and recreation, to powerful drugs for treating neuropsychiatric…
The a16z ShowDevelopers as Creatives
The rise of developers -- as buyers, as influencers, as a creative class -- is a direct result of "software eating the world", and of key shifts in IT from…
The a16z ShowSection 230: Everything You Need to Know -- Tweets, Free Speech, Beyond
All about section 230 of the Communications Decency Act -- in what Wired senior writer (and host of the Get Wired podcast) described as "one of the…
The a16z ShowBaumol's Cost Disease, in Healthcare... and Where We Go Next
If software’s eating the world -- and more specifically, bringing costs down and increasing productivity through entire industries -- why have some industries…
The a16z ShowWords of 2020! (and Metaphors, and Interfaces of the Year)
"In a year that left us speechless, 2020 has been filled with new words unlike any other”... so it's unprecedented that for the first time, the Oxford English…
The a16z ShowThe Machine That Made the Vaccine: Company, Platform, Innovation
In this special episode of Bio Eats World -- which aired right after the FDA authorized Moderna's mRNA vaccine for emergency use -- Moderna CEO Stephane Bancel…
The a16z ShowThe PPP Omnibus: Eminent Domain, Fraud, and Fintech
This episode features two relevant but previously recorded episodes, discussing the relevance of the Paycheck Protection Program (or PPP) from the Small…
The a16z ShowThe Holy Grail of Social + Fintech
The intersection of social and finance—as well as shifting attitudes around what we share about money online—have given way to an ambitious new wave of…
The a16z ShowOn Fear and Leadership: Product to Sales CTOs & CEOs
There's a few ontologies for describing the phases leaders -- and their startups -- go through, whether it's product-sales-etc. or pioneer to settler. In any…
The a16z ShowOn Food As Medicine (A Holiday Snack)
What happens if we treat food as a medicine in the healthcare system: How, where, and who (pays)? What role can technology play in increasing access…
The a16z ShowCrypto Creators: On Art Galleries to 'Tokenized' Collectibles
This episode features Q&As with two artists who are exploring crypto-powered auction sites and marketplaces – this is part of our ongoing series on the creator…
The a16z ShowWhat to Know about Those Vaccines
A vaccine for COVID seems to be (almost) here… or is it? What’s hype/ what’s real beyond the headlines (and beyond the press release), when it comes to the…
The a16z ShowThe Social Serendipity of Cloud Gaming
True cloud-native games—those exclusive to and solely playable within the cloud—are poised to revolutionize gameplay and unlock new avenues of…
The a16z ShowThe Great Data Debate
Lakes v. warehouses, analytics v. AI/ML, SQL v. everything else... As the technical capabilities of data lakes and data warehouses converge, are the separate…
The a16z ShowHow to Moderate Talks, Panels, Meetings, More (Virtual and Beyond!)
How to moderate good, productive discussions and navigate tricky conversations is top of mind -- whether doing a panel, conducting a live event, presenting a…
The a16z ShowTextiles as Tech, Science, Math, Culture... or Civilization
"The most profound technologies are those that disappear. They weave themselves into the fabric of everyday life until they're indistinguishable from it." That…
The a16z ShowData Alone Is Not Enough: The Evolution of Data Architectures
Data, data, data – it’s long been a buzzword in the industry, whether big data, streaming data, data analytics, data science, even AI & machine learning — but…
The a16z ShowDesigning for, Marketing to, and Partnering With Gen Z
Gen Z—those born between 1995 and 2010—now makes up 35 percent of the population and represent $143 billion dollars in spending power. This episode is all…
The a16z ShowThe Present Future of Audio: Talk, Music, Video, Interactivity
We've already talked a lot about podcasting, both evolution of the industry as well as the form, but where are we going with the future of audio, more broadly?…
The a16z ShowTracking the Trends: AI, WebRTC, Crypto, and Full Stack Startups
Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts…
The a16z ShowHow to Decide, Convey vs. Convince, & More
It seems like investors are especially obsessed with the psychology of decision making -- high stakes, after all -- but all kinds of decisions, whether in life…
The a16z ShowFintech for Gen Z and Millennials
Millennials and Gen Z have been hard-hit by the one-two punch of the 2008 and 2020 financial crises. That experience has radically shaped their approach to…
The a16z ShowDegrading Drugs for Problem Proteins: Journal Club now on Bio Eats World (ep 2)
Welcome to the second episode of Bio Eats World, a brand new podcast all about how biology is technology. Bio is breaking out of the lab and clinic and into…
The a16z ShowThe Biology of Aging: Introducing Bio Eats World (ep 1)
Welcome to the first episode of Bio Eats World, a brand new podcast all about how biology is technology. Bio is breaking out of the lab and clinic and into our…
The a16z ShowTikTok & Beyond: The Algorithm Question, The Future of Product
With the U.S. tech partnership for TikTok being finalized, what happens if source code is excluded (and more specifically, the For You Page algorithm), given…
The a16z ShowThe New Fan Club: Creators, Fans, and the Power of Markets (& Crypto)
Today’s episode, part two in our two-part series on the Creator Economy, focuses on the new potential revenue streams and fan-engagement models opened up by…
The a16z ShowSo You Want to Launch a Newsletter: Tips From Substack Writers
This episode, part one in a two-part series on the Creator Economy, explores the process and economics behind creating an independent newsletter. In this…
The a16z ShowDesigning a Culture of Reinvention
Since Netflix started in the late 90s as a DVD-by-mail rental service competing with Blockbuster, it has completely reinvented itself... twice – first, when it…
The a16z ShowHeroes & Myths in Entrepreneurship -- Guy Raz
"I'm in a movie, but it's the wrong movie." For better or for worse, we tell the story of entrepreneurs as one of the mythical hero's journey: that's there's a…
The a16z ShowThe Question of Education
Monopoly, oligopoly, cartel. All three of those words can describe the (not so) modern education system today, given the cost structures, economics, and…
The a16z ShowPandemic Relief and Fraud: Willful Deceit or Design Defect?
This episode examines the potential for misuse and fraud among those applying for the Paycheck Protection Program (PPP)—and how fintech and software provide…
The a16z ShowMeasuring & Managing Community Orgs, Developer Relations and Beyond
Okay, so we know community is important -- whether for developer relations for your product or other types of communities -- but how do we measure the success…
The a16z ShowReining in Complexity: Data Science & Future of AI/ML Businesses
There is no spoon. Or rather, “There is no such thing as ‘data’, there’s just frozen models”, argues Peter Wang, the co-founder and CEO of Anaconda — who also…
The a16z ShowOnline Learning and the Ed Tech Debate
This episode is all about education and technology, a topic that’s especially top of mind this week as students in much of the country return to…
The a16z ShowOn Vaccines and Vaccinology, in COVID and Beyond
WHEN are we going to have a COVID-19 vaccine, and how the heck are we going from (what’s been traditionally been up to) 12 years or so of vaccine development…
The a16z ShowTurning Open Source Developers Into Superfans
In this episode, we continue our community series with a recent discussion that applies to many kinds of community building. Today’s topic: How do you create a…
The a16z ShowJournal Club: Slaying the Sleeper Cells of Aging with CAR T
CAR T therapy is a groundbreaking medicine that uses engineered T cells to attack cancer. But CAR T cells (that is, chimeric antigen receptor T cells) can be…
The a16z ShowWorking, Making, Creating in Public... and Private
We're living in an unprecedented era of online collaboration, coordination, and creation. All kinds of people are coming together -- whether in an open source…
The a16z ShowGPT-3: What's Hype, What's Real on the Latest in AI
In this episode -- cross posted from our 16 Minutes show feed -- we cover all the buzz around GPT-3, the pre-trained machine learning model from OpenAI that’s…
The a16z ShowTaking the Pulse on Medical Device Security
Many don’t realize we even need to think about the possibility of security hacks when it comes to things like pacemakers, insulin pumps, and more. But when…
The a16z ShowJournal Club: A New Path to Antibiotic Resistance
Ever since the discovery of antibiotics, microbiologists have worried about and studied how bacteria acquire resistance to these drugs. Adding to the…
The a16z ShowCybercrime, Incorporated
A dive into the sociological, operational, and tactical realities of this murky underworld, Lusthaus and de la Garza discuss who the players are, what they are…
The a16z ShowHow Transparent Pricing Drives Healthcare Change
Dr. Marty Makary—surgical oncologist at Johns Hopkins University School of Medicine, and health policy and innovation expert—has long been a passionate…
The a16z ShowPreserving Digital History: How to Close the Web's 'Memory Hole'
More than 98% of the information on the web is lost within 20 years, and huge gaps exist in our digital and cultural history. Zoran Basich and Alex Pruden of…