Shows / Aging-US
Aging-US
Aging is dedicated to advancing our understanding of the biological mechanisms that drive aging and the development of age-related diseases. Our mission is to serve as a platform for high-quality research that uncovers the cellular, molecular, and systemic processes underlying aging, and translates these insights into strategies to extend healthspan and delay the onset of chronic disease. Read about the Aging Scientific Integrity Process: https://aging-us.com/scientific-integrity
Episodes
Aging-USLifestyle Intervention Linked to Slower Biological Aging Markers in Older Men
BUFFALO, NY — June 25, 2026 — A new #research paper was #published in Volume 18 of Aging on May 29, 2026, titled “Short-term responsiveness of DNA…
Aging-USResearchers Identify Key Signaling Pathway Driving Muscle Cell Aging
BUFFALO, NY — June 23, 2026 — A new #research paper was #published in Volume 18 of Aging on May 28, 2026, titled “p38MAP kinase regulates senescence in human…
Aging-USDo Exergames Improve Mood and Mental Well-Being in Older Adults?
As people live longer, maintaining mental well-being has become an increasingly important part of healthy aging. While regular physical activity is known to…
Aging-USChildhood Adversity May Leave Lasting Biological Scars Decades Later
BUFFALO, NY — June 18, 2026 — A new #research paper was #published in Volume 18 of Aging on May 26, 2026, titled “Early-life determinants of cardiometabolic…
Aging-USEDITORS’ CHOICE: Epigenetic Aging Biomarkers Respond to Exercise and Dietary Intervention
Each month, we will highlight a paper published in Aging chosen as the “Editors’ Choice.” These selections are handpicked by our editors and accompanied by a…
Aging-USCommon Aging Mechanisms May Link Vision Loss Disorder to Increased Risk of Certain Cancers
BUFFALO, NY — June 16, 2026 — A new #research paper was #published in Volume 18 of Aging on May 22, 2026, titled “Systemic cancer risk profile in neovascular…
Aging-USPhysics Meets Aging: Researchers Lay the Foundations of Gerophysics
BUFFALO, NY — June 11, 2026 — A new #meetingreport was #published in Volume 18 of Aging on May 14, 2026, titled “Foundations of Gerophysics.” The report was…
Aging-USAging Muscle Follows Different Genetic Programs in Mice and Humans
BUFFALO, NY — June 10, 2026 — A new #research paper was #published in Volume 18 of Aging on May 18, 2026, titled “Transcriptional programs diverge in aging…
Aging-USBlood Tests and Gut Bacteria May Help Reveal Your Biological Age
Why do some people appear to age faster than others, even when they are the same age? Researchers increasingly believe that chronological age tells only part…
Aging-USThirty Years After Discovery of SA-β-gal: Researchers Revisit the Hallmarks of Cellular Senescence
BUFFALO, NY — June 5, 2026 — A new #review was #published in Volume 18 of Aging on May 15, 2026, titled “Blue period – features of senescence 30 years after…
Aging-USSenescent Muscle Cells Send Molecular Messages That May Contribute to Age-Related Muscle Decline
BUFFALO, NY — June 3, 2026 — A new #research paper was #published in Volume 18 of Aging-US on May 15, 2026, titled “Extracellular vesicles released by…
Aging-USDNA Methylation Clocks May Help Explain How Social Inequality Influences Mortality
BUFFALO, NY — May 27, 2026 — A new #research paper was #published in Volume 18 of Aging-US on May 8, 2026, titled “The mediating role of DNA methylation clocks…
Aging-USExtending Healthspan Through Public Health and Longevity Medicine
BUFFALO, NY — May 20, 2026 — A new #editorial was #published in Volume 18 of Aging-US on May 18, 2026, titled “Public health in the age of longevity…
Aging-USMethylene Blue May Help Protect Hair Follicle Stem Cells from Aging and Metabolic Stress
BUFFALO, NY — May 19, 2026 — A new #research paper was #published in Volume 18 of Aging-US on May 5, 2026, titled “Methylene blue protects hair follicle stem…
Aging-USEDITORS’ CHOICE: Epigenetic age acceleration with MRI biomarkers of aging and Alzheimer’s...
Each month, we will highlight a paper published in Aging-US chosen as the “Editors’ Choice.” These selections are handpicked by our editors and accompanied by…
Aging-USAnti-Aging Strategies Aim to Target Harmful Senescent Cells While Preserving Beneficial Ones
BUFFALO, NY — May 15, 2026 — A new #review was #published in Volume 18 of Aging-US on May 4, 2026, titled “Cellular senescence: from pathogenic mechanisms to…
Aging-USGlutathione Pathway May Hold the Key to Safer Anti-Obesity Interventions
Efforts to improve metabolic health through dietary interventions often come with trade-offs. Some approaches that reduce obesity or extend lifespan in…
Aging-USAging Immune Systems Show Reduced Ability to Clear Tuberculosis During Treatment
BUFFALO, NY — May 12, 2026 — A new #research paper was #published in Volume 18 of Aging-US on May 4, 2026, titled “Host immunosenescence compromises…
Aging-USLarge-Scale Multi-Omics Study Aims to Decode Aging in the Indian Population
BUFFALO, NY — May 7, 2026 — A new #research paper was #published in Volume 18 of Aging-US on April 24, 2026, titled “The BHARAT study: a multi-modal…
Aging-USHuman Telomerase Shows Selective Cross-Species Activity, Revealing Limits of Animal Models
BUFFALO, NY — May 5, 2026 — A new #research paper was #published in Volume 18 of Aging-US on April 13, 2026, titled “Cross species activity of TERT human…
Aging-USAging-US Supports the NOVA Conference 2026
On April 25, 2026, the NOVA (Neuroscience of Vitality and Aging) Conference brought together a dynamic and interdisciplinary audience in Boston, MA. With over…
Aging-USStage-Specific Gene Expression Changes Reveal Early Triggers of Cellular Aging
BUFFALO, NY — April 29, 2026 — A new #research paper was #published in Volume 18 of Aging-US on April 10, 2026, titled “Stage-dependent transcriptomic changes…
Aging-USP38 MAPK–Driven Epigenetic Regulation Identified as a Key Mechanism in Lung Fibrosis
Aging has long been linked to a range of biological processes, including cellular senescence, epigenetic changes, and chronic tissue remodeling. Yet, these…
Aging-USFrom Hydra to Rotifers: A New Hypothesis Explores Pathways to Delay Aging in Humans
BUFFALO, NY — April 27, 2026 — A new #hypothesis paper was #published in Volume 18 of Aging-US on April 8, 2026, titled “From Hydra to rotifer and beyond…
Aging-USEpigenetic Aging Linked to MRI Signatures of Neurodegeneration but Not General Brain Aging
BUFFALO, NY — April 23, 2026 — A new #research paper was #published in Volume 18 of Aging-US on April 7, 2026, titled “Association of epigenetic age…
Aging-USGlobal Experts Highlight Path Toward Actionable Interventions in Human Aging
BUFFALO, NY — April 21, 2026 — A new meeting report was published in Volume 18 of Aging-US on April 6, 2026, titled “Toward actionable interventions in human…
Aging-USModeling Premature Aging in Yeast Reveals Key Effects of Progerin on Cellular Lifespan
BUFFALO, NY — April 17, 2026 — A new #research paper was #published in Volume 18 of Aging-US on April 3, 2026, titled “Modeling premature aging in yeast via…
Aging-USGene–Phenotype Catalogue Provides New Insights into Premature Aging Disorders
BUFFALO, NY — April 15, 2026 — A new #research paper was #published in Volume 18 of Aging-US on March 30, 2026, titled “A manually curated gene–phenotype…
Aging-USLongevity & Aging Series (S4, E3): Dr. Ricardo Costeira
In this episode of the Longevity & Aging Series (S4, E3), Dr. Ricardo Costeira of King’s College London joins host Dr. Yuan Zhao of Queen Mary University of…
Aging-USDecline in Glycolytic ATP Production Proposed as a Fundamental Mechanism Limiting Lifespan
Aging has long been attributed to a range of biological processes, including DNA damage, telomere shortening, and mitochondrial dysfunction. Yet, these…
Aging-USEDITORS’ CHOICE: Plant-based dietary patterns are associated with slower epigenetic aging
Each month, we will highlight a paper published in Aging-US chosen as the “Editors’ Choice.” These selections are handpicked by our editors and accompanied by…
Aging-USATF5 Required for Maintaining Mitochondrial Homeostasis and Skeletal Muscle Health During Aging
BUFFALO, NY — April 9, 2026 — A new #research paper was #published in Volume 18 of Aging-US on March 27, 2026, titled “ATF5 is required for the maintenance of…
Aging-USHypertonic Saline Plus Furosemide Linked to Lower Inflammatory and Remodeling Markers in ADHF
BUFFALO, NY — April 7, 2026 — A new #research paper was #published in Volume 18 of Aging-US on March 26, 2026, titled “Effects of intravenous furosemide plus…
Aging-USBOLD Variability Modulation Linked to Age-Specific Bimanual Performance
BUFFALO, NY — April 2, 2026 — A new #research paper was #published in Volume 18 of Aging-US on March 24, 2026, titled “Age-specific relationship between the…
Aging-USIL6 and IL6R: Opposing Forces of Inflammation That Shape Human Survival
Inflammation is a double-edged sword. It defends the body against infection and injury, yet when it becomes chronic, it can accelerate aging and fuel the very…
Aging-USPlant-Based Dietary Patterns Linked to Slower Epigenetic Aging
BUFFALO, NY — March 31, 2026 — A new #research paper was #published in Volume 18 of Aging-US on March 20, 2026, titled “Plant-based dietary patterns are…
Aging-USExergames Could Improve Mood in Older Adults
BUFFALO, NY — March 25, 2026 — A new #review was #published in Volume 18 of Aging-US on March 18, 2026, titled “What are the effects of exergames on the mood…
Aging-USNew Blood- and Microbiome-Based Neural Networks Forecast Human Biological Age
BUFFALO, NY — March 23, 2026 — A new #research paper was #published in Volume 18 of Aging-US on March 12, 2026, titled “Blood biochemical and gut microbiotic…
Aging-USLongevity & Aging Series (S4, E2): Dr. David Gems
Dr. David Gems from University College London joins new host Dr. Yuan Zhao from Queen Mary University of London to discuss a review they co-authored in Volume…
Aging-USHealthy Life Extension Positioned as Geroscience’s North Star
BUFFALO, NY — March 18, 2026 — A new #editorial was #published in Volume 18 of Aging-US on March 10, 2026, titled “Healthy life extension: Geroscience’s north…
Aging-USMitochondrial Circular RNAs: New Players in Human Aging
The aging of an organism is reflected not only in the function of its organs but also in the molecular signatures written into its cells. For years, scientists…
Aging-USImpact Journals to Participate at AACR Annual Meeting 2026 in San Diego
BUFFALO, NY – March 16, 2026 – Impact Journals (publisher of Aging-US, Oncotarget, Oncoscience, and Genes & Cancer), is pleased to announce its participation…
Aging-USBSO Recapitulates Anti-Obesity Effects of Sulfur Amino Acid Restriction Without Bone Loss
BUFFALO, NY — March 13, 2026 — A new #research paper was #published in Volume 18 of Aging-US on March 2, 2026, titled “D, L-Buthionine-(S, R)-sulfoximine…
Aging-USP38 MAPK Linked to Epigenetic Activation of Fibrotic Genes in Senescent Lung Fibroblasts
BUFFALO, NY — March 10, 2026 — A new #research paper was #published in Volume 18 of Aging-US on March 3, 2026, titled “P38 MAPK is involved in epigenetic…
Aging-USAging-US Editors' Choice (March, 2026)
Biomarkers of aging help researchers understand how diseases influence the body over time. However, most current biomarkers rely on measurements from mixed…
Aging-USTictock: A Single-Cell Clock Measures Immune Aging in Viral Infections
Aging reshapes the immune system in two fundamental ways: it alters the proportions of different immune cell types circulating in the blood, and it induces…
Aging-USNext-Generation Metabolic Theory Suggests Glycolytic ATP Decline May Limit Lifespan
BUFFALO, NY — March 3, 2026 — A new #research perspective was #published in Volume 18 of Aging-US on February 24, 2026, titled “A decline in glycolytic ATP…
Aging-USStudy Identifies Opposing Roles for IL6 and IL6R in Long-Term Mortality
BUFFALO, NY — February 27, 2026 — A new #research paper was #published in Volume 18 of Aging-US on February 6, 2026, titled “Causal effects of inflammation on…
Aging-USAcknowledgment of 2025 Reviewers
Aging-US sincerely thanks all reviewers who contributed their expertise and time during 2025. Rigorous and constructive peer review is essential to scientific…
Aging-USStudy Identifies Aging-Associated Mitochondrial Circular RNAs
BUFFALO, NY — February 24, 2026 — A new #research paper was #published in Volume 18 of Aging-US on February 10, 2026, titled “Aging-associated mitochondrial…
Aging-USNew Single-Cell Transcriptomic Clock Reveals Intrinsic and Systemic T Cell Aging in COVID-19 and HIV
BUFFALO, NY — February 19, 2026 — A new #research paper was #published in Volume 18 of Aging-US on February 8, 2026, titled “Single-cell transcriptomics reveal…
Aging-USPolyploidy-Induced Senescence May Drive Aging, Tissue Repair, and Cancer Risk
BUFFALO, NY — February 18, 2026 — A new #editorial was #published in Volume 18 of Aging-US on February 8, 2026, titled “Polyploidy-induced senescence: Linking…
Aging-USHow Aging Leads to Chronic Disease: A Two-Stage Model
Aging has long been explained in different ways. One traditional view is that it results from the gradual accumulation of molecular damage over time. Another…
Aging-USEpigenetic Changes in Sperm May Explain Association Between Paternal Age and Autism Risk
While maternal health has traditionally been central to research on pregnancy and child development, there is growing recognition that paternal factors also…
Aging-USLongevity & Aging Series (S4, E1): Fedor Galkin
Senior Scientist Fedor Galkin from Insilico Medicine in Abu Dhabi, UAE, joins Dr. Evgeniy Galimov to discuss a research paper he co-authored in Volume 17…
Aging-USChocolate Compound Linked to Slower Biological Aging
When we think of aging, we often picture wrinkles or gray hair. But aging also occurs deep within our cells. One key area of research focuses on “epigenetic…
Aging-USHow Aging Leads to Disease: New Two-Stage Model Explains Age-Related Illness
BUFFALO, NY — January 20, 2026 — A new #review was #published in Volume 17, Issue 12 of Aging-US on December 30, 2025, titled “Aging as a multifactorial…
Aging-USAge-Related Changes in Sperm DNA May Play a Role in Autism Risk
BUFFALO, NY — January 16, 2026 — A new #research paper was #published in Volume 17, Issue 12 of Aging-US on December 29, 2025, titled “Age-specific DNA…
Aging-USCD47 Antisense Therapy Improves Glucose Control and Lipid Balance in Aging Mice
BUFFALO, NY — January 15, 2026 — A new #research paper was #published in Volume 17, Issue 12 of Aging-US on December 1, 2025, titled “CD47 antisense…
Aging-USAging-US Editors' Choice (January, 2026)
The results of studies revealed in the paper #published in Volume 17, Issue 12, titled “Age-specific DNA methylation alterations in sperm at imprint control…