Epigenetic Changes in Sperm May Explain Association Between Paternal Age and Autism Risk
While maternal health has traditionally been central to research on pregnancy and child development, there is growing recognition that paternal factors also play a role, particularly the father’s age. Several studies have found a modest increase in risk of neurodevelopmental conditions, including autism spectrum disorder, among children born to older fathers. However, the biological mechanisms underlying this association are still not fully understood. One emerging explanation involves epigenetics, chemical modifications that influence how genes are expressed without altering the underlying…
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