Shows / BioTalk Unzipped
BioTalk Unzipped
BioTalk Unzipped, hosted by Gregory Austin and Dr. Chad Briscoe, unzips the stories behind medical progress through candid, intelligent, and often entertaining conversations with leaders across biotechnology, pharmaceuticals, medical technology, clinical research, bioanalysis, and drug development. Each episode explores the science, strategy, setbacks, breakthroughs, and human stories shaping the future of medicine. From first-in-human trials and biomarkers to oncology, rare disease, AI…
Episodes
BioTalk UnzippedWhy Finding the Right Drug Dose Is So Difficult | Dr. Ewoud-Jan van Hoogdalem
A drug shows promise in a small patient study. How much does that tell you about the dose you should test next? Gregory Austin and Dr. Chad Briscoe explore…
BioTalk UnzippedIs AI Changing Scientists? The Future of Pharma with Dr. Rob Dodge
Rob Dodge says AI has made him an expert Python programmer, even though he never took a class in it. But does having new capabilities change what it means to…
BioTalk UnzippedDo Clinical Trials Take Too Much Blood? Patient-Centric Sampling with Joleen White
Clinical trials often collect far more blood than an assay actually needs. Dr. Joleen White asks a more disciplined question: What information is required to…
BioTalk UnzippedWhy Gene Therapy Is Still So Hard to Manufacture at Scale | Phillip Ramsey
Why is gene therapy still so difficult to manufacture at scale after decades of progress? Phillip Ramsey, Chief Technical Officer at Sangamo Therapeutics…
BioTalk UnzippedHer Daughter’s Brain Tumor Turned Her Into a Biotech Founder | Tracy Ryan
A mother’s search for answers to her daughter’s relentless brain tumor led her into natural killer cell biology, cancer immunotherapy, and biotech…
BioTalk UnzippedThe Future of Oncology Drug Development | Dr. Lakshmi Amaravadi
Oncology drug development is becoming more complex, and bioanalysis can no longer be treated as simple drug measurement. Sponsored by Leucentra…
BioTalk UnzippedActive Machine Learning for Drug Discovery & Nanomedicine with Dr. Daniel Reker
Can artificial intelligence help make cancer therapies safer, more targeted, and more effective? In this episode of BioTalk Unzipped, Gregory Austin sits down…
BioTalk UnzippedWhy Haven’t We Cured Cancer Yet? | Dr. Bob Liu Explains
Why haven’t we cured cancer yet? A Genentech scientist explains the real reason. In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit…
BioTalk UnzippedThe Intersection of Biotech, Patent Law, and AI with Dr. Kate Neville, IP Attorney
Recorded October 31, 2025 In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Kate Neville, immunologist turned seasoned…
BioTalk UnzippedLong-acting Cell-Based Gene Therapy, Fabry Disease and Beyond with Glafabra CEO, Dr. Chris Hopkins
In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe sit down with Glafabra CEO: Dr. Chris Hopkins, geneticist, biochemist, and…
BioTalk UnzippedFail Fast, Learn Faster: Drug Development in Rare Disease with Dr. Binodh DeSilva
In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Binodh DeSilva, Senior Vice President of Bioanalysis at Ultragenyx…
BioTalk UnzippedUnlocking Antibody Development with AI with Dr. Pin-Kuang Lai
In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe interview Asst. Professor Pin-Kuang Lai from Stevens Institute of Technology…
BioTalk UnzippedThe Science and Hope of Brain Cancer with Dr. Robert Thorne, Denali Therapeutics
In this powerful episode (#35) of BioTalk Unzipped, recorded live at the AAPS NBC conference in Boston, Gregory Austin engages in a deep conversation with a…
BioTalk UnzippedInside AAPS NBC with AAPS President Dr. Russ Weiner
In this special episode (#34) of BioTalk Unzipped, recorded live at the AAPS NBC conference in Boston, Gregory Austin and Dr. Chad Briscoe sit down with AAPS…
BioTalk UnzippedBuilding Successful Life Science Companies with Katrina Rogers
In this powerful episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Katrina Rogers, a 25-year life sciences veteran, biotech equity…
BioTalk UnzippedNavigating Challenges in Drug Discovery with Dr. Alfred Botchway
In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Alfred Botchway, CEO of Attentive Science, to discuss his journey in…
BioTalk Unzipped2024 Year In Review: BioTalk Unzipped
In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe reflect on their journey over the past year, discussing key themes and insights…
BioTalk UnzippedWomen in Pharmaceutical Sciences and their Allies with Dr. Ines Santos and Dr. Julie Sable
In this episode of BioTalk Unzipped, hosts Gregory Austin and Chad Briscoe welcome Dr. Ines Santos and Dr. Julia Sable to discuss their experiences and…
BioTalk UnzippedCan AI Become Your Doctor? FDA Regulation, Medical Devices & the Future of Healthcare
Could artificial intelligence become your doctor someday? In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Alex…
BioTalk UnzippedThe Future of Dosing: Pharmacometrics, Oncology & Virtual Trials with Dr. Nathan Teuscher
In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe continue their conversation with Dr. Nathan Teuscher, a clinical pharmacology and…
BioTalk UnzippedThe Future of Pharmacometrics with Dr. Nathan Teuscher
In this episode of BioTalk Unzipped, hosts Gregory Austin and Chad Briscoe welcome Dr. Nathan Teuscher, a seasoned expert in clinical pharmacology and…
BioTalk UnzippedWill FDA’s New LDT Rule Slow Drug Development? with Dr. Mark Arnold
In this episode of BioTalk Unzipped, host Gregory Austin and co-host Chad Briscoe engage with Dr. Mark Arnold, a distinguished bioanalytical thought leader…
BioTalk UnzippedDigital Twins: The Future of Drug Discovery with Dr. Tomáš Helikar
BioTalk Unzipped, hosts Gregory Austin and Chad Briscoe engage with Dr. Tomas Helikar in an exciting discussion on the future of AI, digital twins, and…
BioTalk UnzippedTransforming Immunology: The Promise of Digital Twins with Dr. Tomáš Helikar
Dr. Tomas Helikar, a leading researcher in bioinformatics and systems biology, delves into groundbreaking work on developing a personalized immune digital…
BioTalk UnzippedHow AI is Transforming Drug Development: Reflections from AAPS - PharmSci 360 with Dr. Mark Arnold
Dr. Mark Arnold, a distinguished bioanalytical thought leader with an impressive track record in supporting drug development programs. Mark is the Owner and…
BioTalk UnzippedBiotech Funding Trends and the Rise of Digital Twinning with CEO Scott Ogle
EP-23. In the second half of this compelling conversation on BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe continue their deep dive with Scott Ogle…
BioTalk UnzippedTechnology Meets Purpose: Transforming Clinical Trials with CEO Scott Ogle
Summary In this 22nd episode of BioTalk Unzipped, host Gregory Austin and co-host Chad Briscoe engage with Scott Ogle, CEO of TruTechnologies, discussing his…
BioTalk UnzippedMentoring in Pharmaceutical Science with Dr. Jim Shen
Mentoring in Pharmaceutical Science with Dr. Jim Shen Summary In Episode 21 of BioTalk Unzipped, host Gregory Austin and co-host Dr. Chad Briscoe interview Dr…
BioTalk UnzippedGreat Advances in Cancer Research with Dr. Jim Shen
In this episode (EP20) of BioTalk Unzipped, host Gregory Austin and co-host Dr. Chad Briscoe interview Dr. Jim Shen, the Executive Director and Head of…
BioTalk UnzippedThe Future of Hybrid Healthcare | Chuck Piccirillo
Patients increasingly expect healthcare to work the way the rest of their lives work: flexibly, digitally, and around their individual needs. Chuck Piccirillo…
BioTalk UnzippedGenetic Diagnostics and the Rise of Student CEOs | Dr. Jonathan Hill
Could future physicians combine a patient’s genome with artificial intelligence to make faster, more precise diagnoses? Dr. Jonathon Hill returns to BioTalk…
BioTalk UnzippedHow AI Is Helping Diagnose Disease | Chuck Piccirillo
Technology can make healthcare more sophisticated. The harder question is whether it actually makes healthcare better for the patient. Chuck Piccirillo, CEO of…
BioTalk UnzippedReptiles, Toxicology, and the Future of Cell and Gene Therapy | Dr. Andy Vick
What can reptile venom teach us about medicine, and what separates merely good scientific work from truly great work? Dr. Andy Vick returns to BioTalk Unzipped…
BioTalk UnzippedAmyloidosis, Drug Safety, and a New Therapeutic Hope | Dr. Andy Vick
Drug development is ultimately a balancing act: can a therapy create meaningful benefit without introducing unacceptable risk? Dr. Andy Vick joins BioTalk…
BioTalk UnzippedA New Path to Earlier Alzheimer’s Detection | Dr. Jonathan Hill
What if scientists could read DNA differently, uncover biological signals earlier, and eventually diagnose disease before symptoms become obvious? Dr. Jonathon…
BioTalk UnzippedAI, Pharma, and the Future of Patient Care | Jason Burke
What happens when AI begins designing drugs, healthcare data becomes a strategic asset, and software starts changing faster than companies can adapt? Jason…
BioTalk UnzippedOrganoids, AI, and the Future of Healthcare | Jason Burke
Miniature organs grown from cells. Artificial intelligence making increasingly complex healthcare decisions. Quantum computing. FDA-regulated data systems…
BioTalk UnzippedMelanoma Breakthroughs and the Promise of Curative Therapy | Scott Schliebner
What happens when a treatment has the potential to cure disease rather than manage it for years? Scott Schliebner returns to BioTalk Unzipped for a deeper…
BioTalk UnzippedAI in Rare Disease Trials | Scott Schliebner
Rare disease clinical trials present a problem unlike almost anything else in drug development: how do you run a rigorous trial when the patients you need may…
BioTalk UnzippedLeadership, Diagnostics, and Scientific Integrity | Dr. Russell Grant
How should a scientist react when confronted with a groundbreaking new publication? Dr. Russell Grant returns to BioTalk Unzipped for a conversation about…
BioTalk UnzippedDiagnostics That Change Patient Care | Dr. Russell Grant
What happens when a scientist moves from pharmaceutical development into the world of clinical diagnostics? Dr. Russell Grant joins BioTalk Unzipped to discuss…
BioTalk UnzippedFalse Positives In The AI Explosion with Dr. Stephanie Pasas Farmer
Welcome to Episode 6 of our podcast featuring Dr. Stephanie Pasas Farmer! 🎙️ Join us as we delve into the intricate world of data integrity, unveiling new…
BioTalk UnzippedHow To Start A Company In Bioanalysis with Dr. Stephanie Pasas Farmer
🎙️ Episode 5 of BioTalk Unzipped is here! Join hosts Gregory Austin and Dr. Chad Briscoe as they chat with Dr. Stephanie Pasas Farmer, founder of Ariadne…
BioTalk UnzippedSickle Cell Gene Therapy: Can We Afford a Cure? | Dr. Russ Weiner
In Episode 4, (Part 2 of our conversation with Dr. Russ Weiner - a top scientific leader at Takeda), we boldly explore the Cell and Gene Therapy Industry…
BioTalk UnzippedMiraculous Cures: From Hospice to Survivor with Dr. Russ Weiner
In Episode 3 of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe dive deep into the world of biotech with an exclusive interview featuring the…
BioTalk UnzippedScience is Not a Conspiracy Theory
Why does developing a new medicine remain so difficult, and what happens when artificial intelligence enters the equation? In Episode 2 of BioTalk Unzipped…
BioTalk UnzippedBiotech, Drug Development & the Stories Behind Medical Progress | BioTalk Unzipped Trailer
BioTalk Unzipped explores the science, people, breakthroughs, setbacks, and unexpected stories behind medical progress. Hosted by Gregory Austin and Dr. Chad…
BioTalk UnzippedWhy Biotech Companies Fail
Biotechnology changes lives, but the stories behind those breakthroughs are often far more complicated than the headlines suggest. Welcome to the premiere of…