Latest / Hardiness with Dr Paul Taylor / The Science of Aging, Nutrition, and Hormonal Optimisation with Dr. Michael Aziz

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The Science of Aging, Nutrition, and Hormonal Optimisation with Dr. Michael Aziz · Hardiness with Dr Paul Taylor

• 0:09
  Speaker 1: Doctor Michael isis welcome to the podcast.
• 0:12
  Speaker 2: Thank you so much, Doctor Teller.
• 0:15
  Speaker 1: So, Michael, you are an anti aging doctor. You're also
• 0:20
  Speaker 1: the author of two best selling books. You'd made hundreds
• 0:24
  Speaker 1: of TV appearances. I want to start first of all
• 0:29
  Speaker 1: with your the book that you wrote well sixteen seventeen,
• 0:33
  Speaker 1: sixteen years ago. I think it was the perfect ten
• 0:35
  Speaker 1: diet because looking at that, I think we were very
• 0:39
  Speaker 1: aligned in our thinking of nutrition, which has not been
• 0:42
  Speaker 1: aligned with the establishment over the years. First of all,
• 0:46
  Speaker 1: let's talk about fat now. You argued back in twenty
• 0:50
  Speaker 1: ten that the dietary guidelines around fat was wrong and
• 0:54
  Speaker 1: what do we misunderstand about fat then and what do
• 0:58
  Speaker 1: we still misunderstand now?
• 1:01
  Speaker 2: Well, the reality is that a lot of the things
• 1:04
  Speaker 2: we have learned in the past and medical school and
• 1:06
  Speaker 2: residency and doctors are not aware of that those guidelines
• 1:11
  Speaker 2: were influenced by the soybean lobby who made us believe
• 1:14
  Speaker 2: that natural fat, including saturated fat that were they told
• 1:21
  Speaker 2: us it's bad, they caused cancer and heart attack, were wrong.
• 1:25
  Speaker 2: And that's why doctors were on the wrong side when
• 1:28
  Speaker 2: they tell people not to eat butter and cheese and
• 1:31
  Speaker 2: coconut and all those types of natural fats, and I
• 1:34
  Speaker 2: went against those guidelines back in twenty ten, which is crazy,
• 1:38
  Speaker 2: but I was on the right side at the time,
• 1:41
  Speaker 2: because again, the bad thing is the bad fats and
• 1:45
  Speaker 2: the synthetic fat, the seed oils, the cotton seed oil,
• 1:49
  Speaker 2: the fast food oils, all those types of fat were
• 1:52
  Speaker 2: not supposed to consume. And saturated fat have been cleared
• 1:56
  Speaker 2: from heart attack and stroke, yet they continue to be
• 1:59
  Speaker 2: demonized by the medical establishment, which is really sad.
• 2:04
  Speaker 1: Yeah, and there's still debate going on in nutrition circles
• 2:09
  Speaker 1: like you will still here in Australia with Dietitians Australia
• 2:14
  Speaker 1: that's our governing body, and talking about saturated fat being
• 2:18
  Speaker 1: bad and animal fat. And I always find this, you know,
• 2:23
  Speaker 1: I'll tend to look at things through evolutionary biology and
• 2:28
  Speaker 1: you know, human beings and previous to to our to
• 2:32
  Speaker 1: our species, you know, our whole lineage has been eating
• 2:36
  Speaker 1: animal fat forever. So why on earth would it be
• 2:40
  Speaker 1: designed to be bad for us? It just doesn't make
• 2:42
  Speaker 1: any sense, does it. Yeah.
• 2:45
  Speaker 2: The aughty is you know, they they told us in
• 2:47
  Speaker 2: medical school, butter is bad. We know the French paradox.
• 2:50
  Speaker 2: The French eat a lot of butter and they said, oh,
• 2:53
  Speaker 2: maybe it's the wine. It's not the wine. Actually, butter
• 2:55
  Speaker 2: prevents heart attack. And the French have one of the
• 2:57
  Speaker 2: longest life span in the world. So I say in
• 3:00
  Speaker 2: my books that is not a paradox. The French are
• 3:03
  Speaker 2: doing good and believe it or not. In my second book,
• 3:05
  Speaker 2: The Asious Revolution, one of the countries that have the
• 3:08
  Speaker 2: longest life span is Switzerland and they eat cheese fondu
• 3:12
  Speaker 2: that is melted cheese. And can you believe the amount
• 3:14
  Speaker 2: of saturated fat they eat. I mean, you would think
• 3:16
  Speaker 2: they'd be dying of stroke and heart attack every day,
• 3:19
  Speaker 2: but they have the longest life span in the world,
• 3:21
  Speaker 2: next to Monaco. So yeah, so butter is perfectly fine
• 3:25
  Speaker 2: for our audience that's watching us. Cheese is perfectly okay,
• 3:30
  Speaker 2: Coco butter and dark chocolate is okay. Coco nut in
• 3:34
  Speaker 2: Asian food is perfectly okay. You want to stay away
• 3:36
  Speaker 2: definitely from seed oil, vegetable oils, cotton seed oil, soybean oil,
• 3:41
  Speaker 2: which is all in the processed food, and again they're
• 3:45
  Speaker 2: fine there. Actually are can be protective against heart attack.
• 3:48
  Speaker 2: I would go that to say that much further, they
• 3:51
  Speaker 2: prevent heart attack not cause heart attacks.
• 3:55
  Speaker 1: I think it's interesting when you look at the biochemistry
• 3:57
  Speaker 1: saturated if fat in the body becomes a problem in
• 4:01
  Speaker 1: the presence of high sugar, it's that interaction between the
• 4:06
  Speaker 1: high sugar and how it changes high fatuated fat.
• 4:10
  Speaker 2: And I don't mean to interrupt you, but I think
• 4:13
  Speaker 2: sugar is really bad and cause heart disease when it's
• 4:16
  Speaker 2: combined again with the seed oils, because it causes the
• 4:20
  Speaker 2: cholesterol to be oxidized. So you see another issue that
• 4:23
  Speaker 2: we've been brainwashed at. Cholesterol is a bad thing. But
• 4:26
  Speaker 2: cholesterol by itself is only bad if it's oxidized and
• 4:29
  Speaker 2: it becomes sticky and it sticks to the blood vessels
• 4:32
  Speaker 2: and it causes heart attack. And when does the cholesterol
• 4:34
  Speaker 2: become sticky. It becomes sticky if you smoke from the
• 4:37
  Speaker 2: free radicals, it becomes sticky. If you use a lot
• 4:40
  Speaker 2: of sugar, eat a lot of sugar, or eat refined carbs.
• 4:43
  Speaker 2: You know why bread, white fries, it becomes also oxidized
• 4:46
  Speaker 2: if you use synthetic fat. Again, the seed oils, the
• 4:50
  Speaker 2: free radicals from fast food oils and French fries. It's
• 4:53
  Speaker 2: not from the butter or the cheese.
• 4:55
  Speaker 1: So let's talk about seed oils, right, because that's another
• 5:00
  Speaker 1: topic that is still controversial. You'll have a whole heap
• 5:03
  Speaker 1: of people on one side of the fence, such as
• 5:07
  Speaker 1: you and I tend to be on that side of
• 5:09
  Speaker 1: the fence as well, who say that these commercially produced
• 5:13
  Speaker 1: seed oils are not good for us. And then you
• 5:16
  Speaker 1: have the other side of the fence that say, actually, yes,
• 5:20
  Speaker 1: they're good. And we see that large scale observational studies
• 5:24
  Speaker 1: with seed oils and you know there's no harm in them.
• 5:28
  Speaker 1: So talk our listeners through why you think that seed
• 5:33
  Speaker 1: olds are bad? Like what happens in the Is it
• 5:37
  Speaker 1: the oils themselves, is it the processing, is it the
• 5:40
  Speaker 1: combination and what is actually going on in the body
• 5:43
  Speaker 1: when there's too much amiga six fats and just dive
• 5:47
  Speaker 1: into that whole area for us.
• 5:49
  Speaker 2: Yeah, so for the audience was listening to us, Omega
• 5:52
  Speaker 2: six oils are basically it's good to have them in
• 5:56
  Speaker 2: small amounts in natural form, like eating some corner some peanuts,
• 6:00
  Speaker 2: But when they are extracted from the plant, they're exposed
• 6:03
  Speaker 2: to over a cellsand chemicals, they have a lot of
• 6:08
  Speaker 2: a lot of processing and they are damaging the process
• 6:12
  Speaker 2: they create free radicals. Sometimes they are exposed to an
• 6:16
  Speaker 2: extra hydrogen atom under pressure, so they become hydrogenated, so
• 6:20
  Speaker 2: they become stable when they're heated. This way they can
• 6:22
  Speaker 2: make the French fries crispy and the mists that they
• 6:25
  Speaker 2: are good for us is because when you consume vegetable
• 6:28
  Speaker 2: oil or seed oil, the cholesterol goes down. And the
• 6:30
  Speaker 2: reason cholesterol goes down, so it looks like they're really
• 6:33
  Speaker 2: good for us. The reason cholesterol goes down because our
• 6:36
  Speaker 2: bodies are made of saturated fat. Our cells are made
• 6:40
  Speaker 2: out of saturated fat, my skin, everything is made out
• 6:44
  Speaker 2: of saturated fat. That's what makes the cell stables. If
• 6:47
  Speaker 2: we're made out of liquid, the cells will fall off.
• 6:49
  Speaker 2: So when you are consuming seed oils, your cholesterol goes
• 6:54
  Speaker 2: down because it runs to the tissue. They make the
• 6:56
  Speaker 2: cells more stable. So they look in front of the
• 6:59
  Speaker 2: guy lines and in front of the research, Oh they're good,
• 7:02
  Speaker 2: they're lower cholesterol. But the truth is they're highly estererogenic.
• 7:06
  Speaker 2: They cause us the arteries to get blocked, so that's
• 7:09
  Speaker 2: why you want to stay away from them. And then
• 7:12
  Speaker 2: the other issue is they also cause inflammation. The imbalance
• 7:15
  Speaker 2: between the omega three and the Omega six. You want
• 7:18
  Speaker 2: to have to keep that ratio at one to one
• 7:20
  Speaker 2: when it's twenty to one. That causes inflammation, causes all
• 7:23
  Speaker 2: kinds of issue related and it causes aging as well,
• 7:25
  Speaker 2: accelerated aging, which is one of the things I'm very
• 7:28
  Speaker 2: passionate about. Yeah.
• 7:30
  Speaker 1: So in your book The Perfect Ten Diet, you were
• 7:35
  Speaker 1: the real driver was about balancing key hormones. And let's
• 7:40
  Speaker 1: pick something that is very prevalent today because of the
• 7:44
  Speaker 1: stress of modern life, and that is high levels of
• 7:48
  Speaker 1: cortisol are hyper cortisol emia. Talk our listeners through the
• 7:53
  Speaker 1: darnstream effects of having cordisole re is to high levels
• 7:58
  Speaker 1: for long periods of time.
• 8:01
  Speaker 2: Well, you know, unfortunately people in Australia, people in United States,
• 8:04
  Speaker 2: we have very high cortisol level because of all the
• 8:07
  Speaker 2: stress living in big cities, living in Sydney, living in
• 8:10
  Speaker 2: New York City, and that causes cortisol when it goes up.
• 8:13
  Speaker 2: There's some kind of a link between high cortisol and
• 8:16
  Speaker 2: also insulin level. So cortusol also causes also people to
• 8:22
  Speaker 2: be hungry. It causes high sugar level and.
• 8:24
  Speaker 1: That can lead to weight gain.
• 8:26
  Speaker 2: A person who could be eating the same amount of calories,
• 8:29
  Speaker 2: and a person who's stressed can gain weight. When a
• 8:32
  Speaker 2: person eat the same amount of calories and they're not stressed,
• 8:35
  Speaker 2: they won't gain weight. So there is also a link
• 8:38
  Speaker 2: between cortusol and weight gain. So cortusol is messed up
• 8:42
  Speaker 2: in all Western countries.
• 8:45
  Speaker 1: And Michael just to probably and add a little bit
• 8:48
  Speaker 1: of color to that. Again, if we look at this
• 8:51
  Speaker 1: from an evolutionary biology perspective, I say to people, you know,
• 8:55
  Speaker 1: if you think of our stress response system, there's two elements.
• 8:58
  Speaker 1: There's the fire flight to the ship pesthetic nervous system.
• 9:01
  Speaker 1: That's the equivalent of three minutes of screaming terror on
• 9:04
  Speaker 1: the African savannah when your ancestors were being chased by
• 9:07
  Speaker 1: a lion. And then if that threat is extreme are
• 9:12
  Speaker 1: especially prolonged, that's when the HPI access kicks in and
• 9:17
  Speaker 1: cortisole's released. And traditionally, excuse me, cordisole would be released
• 9:22
  Speaker 1: in periods of hunger and famine. And what it does
• 9:26
  Speaker 1: is it breaks down and some of the amino acids
• 9:30
  Speaker 1: to create blood sugar. But it also lowers our metabolic
• 9:33
  Speaker 1: rate because there's a signal. The traditional signal is like
• 9:38
  Speaker 1: there's not enough calories coming in, so cordisol actually will
• 9:42
  Speaker 1: hold on to every single calorie that's coming in. And
• 9:45
  Speaker 1: that's to your point why two people can be eating
• 9:48
  Speaker 1: exactly the same diet and have the same amount of
• 9:52
  Speaker 1: calories and be the same stable body weight. Initially, one
• 9:57
  Speaker 1: person's got high cordisole, the other one doesn't. The person
• 9:59
  Speaker 1: with high corso will put on with it despite the
• 10:03
  Speaker 1: fact that they're eating the same calories as the person
• 10:05
  Speaker 1: who's not putting on with it.
• 10:07
  Speaker 2: Of course, doctor Taylor, it looks like you're one of
• 10:09
  Speaker 2: my ghostwriters for my first book. We're on the same
• 10:13
  Speaker 2: page here. I have to see people seeing the same
• 10:17
  Speaker 2: thing that I talked about and looking beyond the number
• 10:21
  Speaker 2: of galleries and you just eat that amount and exercise,
• 10:24
  Speaker 2: because that's metabolism is everything. Also, our metabolism is affected
• 10:28
  Speaker 2: by what you eat, by hormones and so on, And
• 10:31
  Speaker 2: that's what my first book was about. The perfect Ing
• 10:34
  Speaker 2: Diet was about balancing not just insolin, which is low
• 10:37
  Speaker 2: carp focus on, but it's also about balancing cortisol by
• 10:41
  Speaker 2: dealing with your stress level and dealing with the fake fats,
• 10:45
  Speaker 2: the hydrogen needed oil, the mess up latin, another hormone
• 10:48
  Speaker 2: that is linked to obesti as well. And I talk
• 10:51
  Speaker 2: about how we just talked about butter and cheese are
• 10:55
  Speaker 2: good for us and not bad, but they're also good
• 10:57
  Speaker 2: to balance sex hormones, which are they go down with
• 11:00
  Speaker 2: the aging process. So when you eat butter, it's good
• 11:02
  Speaker 2: for your tystosterone, it's good for your estrogen for our
• 11:05
  Speaker 2: women listeners, and progesterone because those steps of fat are
• 11:08
  Speaker 2: made out of natural saturated fat. So that's why I
• 11:12
  Speaker 2: need to balance your hormones. You need to deal with
• 11:13
  Speaker 2: your stress to lose weight, and you need to avoid
• 11:17
  Speaker 2: processed food, hydrogenated oil, balance laptin, you know, exercise to
• 11:21
  Speaker 2: raise gross hormone. And that's what the title of the book,
• 11:24
  Speaker 2: The Perfect Ten was a very misleading title. It's all
• 11:27
  Speaker 2: about balancing all the hormones because the problem is low
• 11:30
  Speaker 2: fat diet mess up insulin and you can never lose
• 11:34
  Speaker 2: weight if your insulin is messed up. You can't lose
• 11:36
  Speaker 2: weight if you're eating sugar and low carbs. Only focus
• 11:39
  Speaker 2: on insulin and they neglect all the other hormones. So
• 11:43
  Speaker 2: you focus on a cut the doughnuts, cut the carbs,
• 11:46
  Speaker 2: but then you know what about all the other chemicals.
• 11:49
  Speaker 2: Then I tried that all link to cancer, and that's
• 11:51
  Speaker 2: not my mo for me. It's not only about losing weight,
• 11:55
  Speaker 2: it's also about longevity. You can eat two small fries
• 11:58
  Speaker 2: and you would lose weight. If that's you're what you
• 12:00
  Speaker 2: want to do, just lose weight, but you're not going
• 12:02
  Speaker 2: to have a long lifespan. So the Perfect ten was
• 12:04
  Speaker 2: a clean, balanced diet to balance all hormones, avoid all
• 12:08
  Speaker 2: processed food, nitrites, artificial sweeteners, hydrogenated oil, seed oils. And
• 12:13
  Speaker 2: that's why this book was very, very ahead of its
• 12:16
  Speaker 2: time because I stood against low fat, low carb The
• 12:19
  Speaker 2: popular diet was all the chemicals. And here we.
• 12:22
  Speaker 1: Are, Yeah, that's right, exactly here we are because right
• 12:27
  Speaker 1: now the United States food pyramid has completely changed. Now
• 12:32
  Speaker 1: has it completely caught up with your book? Or would
• 12:36
  Speaker 1: you be would you make tweaks to what is currently there?
• 12:40
  Speaker 1: Right Egypt, So we don't how to build pyramids.
• 12:45
  Speaker 2: My pyramids still stands the rest of the time. The
• 12:49
  Speaker 2: new food pyramid is a lot better because it did
• 12:52
  Speaker 2: things upside down. So now you have fats at the
• 12:55
  Speaker 2: bottom and you have refined carbs all the way on
• 12:58
  Speaker 2: the top. But it's still has a problem because it
• 13:01
  Speaker 2: doesn't differentiate the types of protein you should eat. And
• 13:05
  Speaker 2: in my first book, The Perfect Ten, I talk about
• 13:08
  Speaker 2: the types of protein you should eat because some protein
• 13:12
  Speaker 2: are very good for us and some protein types are
• 13:14
  Speaker 2: not good for us. So it's not a good healthy
• 13:17
  Speaker 2: thing to eat red meat every single day because red meat,
• 13:20
  Speaker 2: when it's grilled, it's also be linked to calling cancer.
• 13:23
  Speaker 2: So you don't want to eat red meat every day
• 13:24
  Speaker 2: or steak every day. You want to eat more peultry
• 13:27
  Speaker 2: and seafood. People who eat beans that a longer life.
• 13:30
  Speaker 2: And the new food pyramid maybe fixed up the problem
• 13:33
  Speaker 2: with the carbs that you don't have to eat bagels
• 13:36
  Speaker 2: and all that stuff, but it still lumps all the
• 13:39
  Speaker 2: protein types together, which is a bad thing.
• 13:42
  Speaker 1: Right, Okay, and let's get I want to take a
• 13:46
  Speaker 1: quick step back to talk about one hormone that you
• 13:49
  Speaker 1: very briefly mentioned, and that's leptin. So leptin for our listeners,
• 13:56
  Speaker 1: you know, it does a couple of things. I always say,
• 13:58
  Speaker 1: latin is why you don't see a five rattlesnake or
• 14:00
  Speaker 1: a fat lion in nature, because it is the hormone that,
• 14:06
  Speaker 1: in my words, it kind of says, hey, move more
• 14:09
  Speaker 1: and eat less because you're you're putting on a bit
• 14:12
  Speaker 1: of weight. It helps us to regulate our body weight.
• 14:14
  Speaker 1: Interesting research shows that if you have a poor night's sleep,
• 14:18
  Speaker 1: leptin is reduced the next day, which means you're a
• 14:22
  Speaker 1: lot less likely to move and you're more likely to overeat.
• 14:25
  Speaker 1: So what other influences other than sleep, what goes into
• 14:31
  Speaker 1: determiningleptom levels? And why is leptin resistance a problem? And
• 14:37
  Speaker 1: I'm sorry one extra bit to this. Do you see
• 14:41
  Speaker 1: leptin resistance going hand in hand with insulin resistance and
• 14:44
  Speaker 1: gluc a chord acord resistance?
• 14:48
  Speaker 2: You know, there was some people who theorize that if
• 14:51
  Speaker 2: you balance lepton, you would lose weight, but they found
• 14:53
  Speaker 2: that people who are really who are overweight also have
• 14:57
  Speaker 2: messed up leptin level have high level. It's affected also
• 15:00
  Speaker 2: by hydrogenated oils, processed food, it's messed up by sugar,
• 15:05
  Speaker 2: it's affected by sleep. So you have to deal with
• 15:08
  Speaker 2: all those factors for you to lose weight. Again, that's
• 15:12
  Speaker 2: why the name of my book is a perfect ten,
• 15:14
  Speaker 2: because you want to balance all hormones, not just deal
• 15:17
  Speaker 2: with obesity with insulin or lepton alone. I mean there's
• 15:20
  Speaker 2: some books I believe that were written, like the Leptin
• 15:22
  Speaker 2: Diet or whatever. It is not to put anybody down,
• 15:26
  Speaker 2: but again, you have to deal with obesiti and the
• 15:30
  Speaker 2: epidemic of obesity we have in many Western countries by
• 15:33
  Speaker 2: dealing with all the hormones. Dialing was your lifestyle, Dealing
• 15:36
  Speaker 2: was your diet, eating the right things and balancing all
• 15:40
  Speaker 2: hormones for you to lose weight.
• 15:42
  Speaker 1: Yeah, and I think you could probably sum up your
• 15:47
  Speaker 1: approach to diet and my approach to diet as eight
• 15:50
  Speaker 1: more like your grandparents than the people today.
• 15:54
  Speaker 2: I told you're my ghost writer, I have done in
• 15:56
  Speaker 2: my first book. You know, you know you've heard of
• 15:58
  Speaker 2: the grandma who ate and drank whole milk and she
• 16:02
  Speaker 2: died at age ninety. And you know she never had
• 16:05
  Speaker 2: an issue. People died a long time ago from pneumonia,
• 16:09
  Speaker 2: from the flu, from tuberculosis. They didn't die of the
• 16:12
  Speaker 2: epidemic of modern or age rated illnesses that we have
• 16:16
  Speaker 2: right now. And yeah, so it's pretty much comes to
• 16:19
  Speaker 2: common sense. You have to eat natural food. You have
• 16:22
  Speaker 2: to stay away from chemicals artificial sweeteners that are link
• 16:25
  Speaker 2: to heart attack and stroke. You have to stay with
• 16:26
  Speaker 2: from nitrites because right now, you know, many people failed
• 16:30
  Speaker 2: a low fat and they went to a different kind
• 16:32
  Speaker 2: of extreme diet. They went to low carb which are
• 16:35
  Speaker 2: now invoked called quito. So a lot of people are
• 16:37
  Speaker 2: eating kiko tikito diets. And you're not gonna get healthy
• 16:40
  Speaker 2: if you just eat it sad with bacon. You're not
• 16:42
  Speaker 2: gonna You may lose weight because you're balancing insulin and
• 16:46
  Speaker 2: you know, but you're not gonna you're not going to
• 16:48
  Speaker 2: live a long life. And processed meat nitrites have been
• 16:51
  Speaker 2: linked to many types of cancer, and we also have
• 16:53
  Speaker 2: an epidemic of cancer in many western countries. It's the
• 16:56
  Speaker 2: second leading cause of death in America, Australia and Europe. So, yeah,
• 17:01
  Speaker 2: we have to lower our chances of getting cancer. And
• 17:05
  Speaker 2: one way is eating the right clean diet. Yeah.
• 17:08
  Speaker 1: I tend to liken nutrition to the world of religion
• 17:13
  Speaker 1: and that there's lots of different religions and there's lots
• 17:16
  Speaker 1: of different eating practices, right. But but as you say,
• 17:20
  Speaker 1: and you know, it is about variety. It's about eating
• 17:24
  Speaker 1: the real food and not excluding particular nutrients. But so
• 17:30
  Speaker 1: let's let's move on from that and let's talk about
• 17:34
  Speaker 1: your new book and that you know your real focus now,
• 17:38
  Speaker 1: which is anti aging. And in your new book you
• 17:41
  Speaker 1: talk about the hallmarks of aging, which I'm a fan
• 17:44
  Speaker 1: of talking about those hallmarks. So now for our listening,
• 17:49
  Speaker 1: they will maybe have something may have heard me talk
• 17:51
  Speaker 1: about the hallmarks of aging before, you know, things like
• 17:56
  Speaker 1: mitochondrial dysfunction, stem cell exhaustion, inflammation, got biosis, etcetera, et cetera.
• 18:02
  Speaker 1: And for you, Michael, is there any of those hallmarks
• 18:07
  Speaker 1: that are really if you were to list them in
• 18:10
  Speaker 1: a hierarchy, is there any that you think are more
• 18:16
  Speaker 1: causes of our influence? The other hallmarks more than others,
• 18:20
  Speaker 1: are our central drivers, whatever way you want to describe it.
• 18:24
  Speaker 2: So there are twelve hallmarks of aging to our listeners,
• 18:27
  Speaker 2: and the whole marks of aging were discovered in twenty twelve.
• 18:32
  Speaker 2: And now this is the first time in history that
• 18:34
  Speaker 2: we know why we get old, why we get sick,
• 18:39
  Speaker 2: and why we die. And many of my predecessors who
• 18:43
  Speaker 2: wrote anti aging books focus on one or two things,
• 18:46
  Speaker 2: and I just feel that people don't have time to
• 18:49
  Speaker 2: waste their time reading about one or two things. And
• 18:51
  Speaker 2: just like I'm dealing with nutrition, we have to attack
• 18:54
  Speaker 2: all the hallmarks of aging, because that's how you slow
• 18:57
  Speaker 2: the aging process and possibly have a lot younger lifespan.
• 19:01
  Speaker 2: But from all the twelve hall marks of aging, I
• 19:03
  Speaker 2: would say that for your to answer your question, the
• 19:06
  Speaker 2: most important one is epigenic alteration and those are the
• 19:10
  Speaker 2: to make it clear, that are the types of things
• 19:13
  Speaker 2: that we do that affect our DNA. And you know,
• 19:17
  Speaker 2: the book is a little scientific, but I had to
• 19:19
  Speaker 2: come up. It took me like four or five years
• 19:20
  Speaker 2: to write it, and I had to make it very simple.
• 19:22
  Speaker 2: And I give an example in my book which I'm
• 19:25
  Speaker 2: going to give to your listeners. I'm saying, imagine Whitney Houston,
• 19:28
  Speaker 2: who had the greatest voice probably in history, and she
• 19:33
  Speaker 2: wanted to become a singer, and she wanted to become famous.
• 19:36
  Speaker 2: And then what happens is she sends a demo of
• 19:39
  Speaker 2: her tape of her songs to the voice. You have
• 19:42
  Speaker 2: the voice in Australia way, we have the voice. Sarah's
• 19:45
  Speaker 2: the same thing. So she sends a demo of her voice,
• 19:48
  Speaker 2: of her songs to the voice. But then the producer,
• 19:52
  Speaker 2: instead of playing her songs with a brand new record player,
• 19:57
  Speaker 2: he plays her this or vinyl record was a damaged needle,
• 20:02
  Speaker 2: and Whitney Houston is so off that she sounds so
• 20:06
  Speaker 2: horrible that she's not even selected to be in the
• 20:10
  Speaker 2: first audition, and the people would never hear her voice.
• 20:14
  Speaker 2: And those are the things that we do that will
• 20:17
  Speaker 2: affect our voice and how we live. So the things
• 20:22
  Speaker 2: that we do, like smoking, eating processed food, eating nitrites,
• 20:28
  Speaker 2: not exercising, getting enough sleep, this is epogenic alteration. It
• 20:33
  Speaker 2: affects how your genome works, it affects how it acts
• 20:37
  Speaker 2: and will become like that Whitney Houston. We never got
• 20:39
  Speaker 2: a chance because of that damaged needle in the record player.
• 20:44
  Speaker 2: So all the bad things, this is the most important
• 20:47
  Speaker 2: hallmark you have to do. So if you want to
• 20:49
  Speaker 2: live a long life, start by eliminating the bad things.
• 20:54
  Speaker 2: Give yourself a score of all the bad things you do.
• 20:57
  Speaker 2: If you smoke, that's the minus one. If you drink
• 21:00
  Speaker 2: call that's the minus one. If you don't get enough
• 21:01
  Speaker 2: sleep that's the minus one. If you have too much
• 21:04
  Speaker 2: stress in your life, that's minus one. The point is
• 21:06
  Speaker 2: to get to zero before you target all the other
• 21:08
  Speaker 2: hallmarks of aging, because that's epigenic alteration. You're affecting your
• 21:12
  Speaker 2: lifespan by dealing with all the negative things that shorten
• 21:15
  Speaker 2: your lifespan.
• 21:16
  Speaker 1: So, just to explain epigenetics for people who may not
• 21:22
  Speaker 1: be familiar with the term, I think an analogy I
• 21:25
  Speaker 1: like to use is if you think of your DNA,
• 21:27
  Speaker 1: your genes. Everybody gets that they're like the hardware in
• 21:31
  Speaker 1: your computer, and the epigenome is like the software that
• 21:35
  Speaker 1: tells the hardware. That's exactly, it's.
• 21:37
  Speaker 2: A software and the hardware so it acts as you
• 21:42
  Speaker 2: tell him to do. So if you do the wrong things,
• 21:44
  Speaker 2: it's going to act in a bad way.
• 21:47
  Speaker 1: And I think something that people don't understand, Michael, is
• 21:51
  Speaker 1: that the influence of nutrition on these epigenetic markers and
• 21:57
  Speaker 1: how that certain new treants actually provide the substrate for
• 22:03
  Speaker 1: our body to regulate these genes. And we're not eating
• 22:07
  Speaker 1: that high nutrient diet, we lose the ability to regulate
• 22:12
  Speaker 1: our genes, to turn them on when they're supposed to
• 22:14
  Speaker 1: be on, to turn them off when they're supposed to
• 22:16
  Speaker 1: be off. That's pretty key, isn't it.
• 22:18
  Speaker 2: Yes, of course that's for our listeners. That's curtuins. Curtuins
• 22:23
  Speaker 2: are they're the CEO of ourselves. They tell the cells.
• 22:27
  Speaker 2: What to do? They affect our longevity and curtuins. You
• 22:30
  Speaker 2: want to turn them on, and you turn them on
• 22:32
  Speaker 2: by eating the superfoods we've heard of, rizveratrol and grapes
• 22:37
  Speaker 2: and the skin of grapes. They're turned on by intermittent fasting.
• 22:41
  Speaker 2: They turn on by extreme cold, by extreme heat, because
• 22:44
  Speaker 2: they're survivor mechanism for us. So you want to have
• 22:48
  Speaker 2: your sturtuin turn on, and that's how you can affect
• 22:51
  Speaker 2: your lifespan and health span and live possibly a longer
• 22:54
  Speaker 2: life in great healths.
• 22:56
  Speaker 1: So let's there. We say we're not original. Research paper
• 23:02
  Speaker 1: was published the Hallmarks of Aging. I remember a year
• 23:07
  Speaker 1: later a research paper came out and it said exercise
• 23:11
  Speaker 1: atten yates the hallmarks of aging, and they proved that
• 23:15
  Speaker 1: exercise affected positively every single one of the original nine
• 23:22
  Speaker 1: hallmarks of aging. Then I think it was twenty twenty three.
• 23:26
  Speaker 1: The researchers who released the original paper on the Hallmarks
• 23:31
  Speaker 1: of aging, they did another paper called an Expanding Universe
• 23:34
  Speaker 1: and identified three more. I think it was inflammation, got this, biosis,
• 23:38
  Speaker 1: one another I can't remember, and exercise positively affects all
• 23:42
  Speaker 1: of those. So exercise it has an impact, a positive
• 23:47
  Speaker 1: impact on every single one of the twelve hallmarks. Absolutely,
• 23:52
  Speaker 1: and so obviously exercise you're a fan of, and what
• 23:57
  Speaker 1: other things influence many of the hallmarks of aging, Like
• 24:02
  Speaker 1: is there any candidate at sight there that you think, hey,
• 24:06
  Speaker 1: this is really important.
• 24:09
  Speaker 2: We're doing like a top ten here. So actually, when
• 24:11
  Speaker 2: I wrote my book, there was nine hallmarks, and then
• 24:13
  Speaker 2: during the writing the books three more hallmarks, I think,
• 24:16
  Speaker 2: But I think I speak of all of them in
• 24:21
  Speaker 2: my book, even though I've limited them to ten because
• 24:23
  Speaker 2: some of them are redundant. But I think the most
• 24:25
  Speaker 2: important hallmark of aging, after what we talked about about
• 24:28
  Speaker 2: Whitney Houston. The second thing would be the gut heals
• 24:31
  Speaker 2: and we see all in the Blue Zones. Those are
• 24:33
  Speaker 2: the five areas in the world where people live to
• 24:36
  Speaker 2: one hundred. That gut heus is very important. You want
• 24:39
  Speaker 2: to take care of your gut bacteria by eating a
• 24:42
  Speaker 2: lot of fiber, probiotics and a lot of good bacteria
• 24:46
  Speaker 2: like probiotics, fermented food. So even in countries that are
• 24:52
  Speaker 2: not part of the Blue Zones, we found like in
• 24:53
  Speaker 2: South Korea they have kimshi and the women there are
• 24:57
  Speaker 2: going to be the first to live to age ninety.
• 24:58
  Speaker 2: So fermented food is very important and the listeners have
• 25:01
  Speaker 2: to make an effort to eat fermented food. If they're
• 25:04
  Speaker 2: all like yoga, they should have something else like a
• 25:07
  Speaker 2: butcha or fermented vegetables or anything to get their gut
• 25:10
  Speaker 2: health in check. Yeah.
• 25:13
  Speaker 1: I think it's only it's only in the last number
• 25:16
  Speaker 1: of years that we've realized the importance of fermented food.
• 25:19
  Speaker 1: I think. I think fiber we've known for many, many years,
• 25:22
  Speaker 1: and now we're getting a bit a bit tighter on
• 25:26
  Speaker 1: the fiber, I would say. And resistant starts in particular
• 25:31
  Speaker 1: feeds your good bugs. But the interesting thing is that
• 25:36
  Speaker 1: the fermented foods they fertilize the grind in your gut microbiome.
• 25:42
  Speaker 1: That seems to be what's happening, right, is that when
• 25:46
  Speaker 1: we eat those fermented foods, it's actually providing the fertilizer
• 25:50
  Speaker 1: so that our good bugs can flourish. And then when
• 25:53
  Speaker 1: you feed the resistance starts, that's when all the good
• 25:56
  Speaker 1: stuff happens. Right. So it is that combination, isn't it?
• 26:00
  Speaker 2: Yes? Because for ours, for our listeners to understand how
• 26:03
  Speaker 2: the god bacteria affect our health and our longevity, the
• 26:07
  Speaker 2: God bacteria has good bacteria and bad bacteria. You want
• 26:10
  Speaker 2: to feed the good bacteria when I get rid of
• 26:12
  Speaker 2: the bad bacteria, and the bad bacteria flourish if you
• 26:14
  Speaker 2: eat too much sugar or cookies, and the good bacteria
• 26:18
  Speaker 2: flourish when you eat you know, fermented food and probiotics
• 26:21
  Speaker 2: and yogurt, and the good bacteria make a vitamin K two,
• 26:24
  Speaker 2: which is a vitamin that is very neglected. And vitamin
• 26:26
  Speaker 2: K two actshibit like draino that opens up pipes in
• 26:30
  Speaker 2: your sink. So vitamin K two prevents the calcium from
• 26:34
  Speaker 2: being deposited in the artery. So I take a very
• 26:36
  Speaker 2: low dose of vitamin K two every single day. And
• 26:40
  Speaker 2: then the good bacteria also make a product called eurylessin,
• 26:43
  Speaker 2: which is very important to make the mitochondria work. And
• 26:46
  Speaker 2: the mitochondria are the battery of ourselves, so sink of
• 26:50
  Speaker 2: ourselves like your cell phone, your iPhone, if it's not charged,
• 26:54
  Speaker 2: it's going to die. You want to keep your mitochondria charged.
• 26:56
  Speaker 2: And the mitochondria gets charged by the urrolyssin. So that's
• 27:00
  Speaker 2: how they got back to the effects longevity.
• 27:02
  Speaker 1: Yeah, that's let's actually let's jump into the mitochondria. A
• 27:06
  Speaker 1: couple of weeks ago, I m C the Mitochondrial Health
• 27:10
  Speaker 1: Conference in Australia, and so I'm all over the mitochondria.
• 27:15
  Speaker 1: I mean you said that, I mean the classic thing there,
• 27:18
  Speaker 1: the powerhouse of the generators of yourself. But we're starting
• 27:22
  Speaker 1: to realize that the mitochondria do so much more. Now.
• 27:27
  Speaker 1: You talked about eurylsten a. Let's talk about some other
• 27:31
  Speaker 1: things that support your mitochondria. I mean, if we go
• 27:35
  Speaker 1: back to exercise. Exercise clearly has an impact on mitochondrial
• 27:40
  Speaker 1: health and can induce mitochondria about genesis as well. But
• 27:45
  Speaker 1: what other what other things are you a fan of
• 27:48
  Speaker 1: in terms of supporting your overall mitochondria, Because if you
• 27:53
  Speaker 1: if your mitochondria aren't working, well that's when you have
• 27:55
  Speaker 1: shit energy, right these people who complain there energy, So
• 27:59
  Speaker 1: your mitochon are not working.
• 28:01
  Speaker 2: Yeah. So for again, for our listeners to understand, the
• 28:03
  Speaker 2: mitochondria are the battery or our cells. And for cells,
• 28:06
  Speaker 2: our cells to work, the mitochondria have to be charged
• 28:09
  Speaker 2: and you need your mitochondria charged and they slow down
• 28:11
  Speaker 2: when we get older. That's why we have less energy.
• 28:14
  Speaker 2: So mitochondria are affected by a molecule called NYD, which
• 28:17
  Speaker 2: is gaining a lot of traction. You have celebrities now
• 28:20
  Speaker 2: taking any D, which is the charger for the mitochondria.
• 28:24
  Speaker 2: You could do it by injection, you could do it
• 28:26
  Speaker 2: by taking a precursor like NMN or NR. The mitochondria
• 28:31
  Speaker 2: are affected by exercise because they create a compound or
• 28:34
  Speaker 2: a pepti called matzi. Some people are taking straight jumping
• 28:37
  Speaker 2: to the pepti called mazi, but that's why how the
• 28:39
  Speaker 2: mitochondria work. And then they're also affected by antioxydants like
• 28:45
  Speaker 2: gluta ion, which is present in food. Some people take
• 28:48
  Speaker 2: it also as in spray or ivy injection. I I
• 28:51
  Speaker 2: try to take an iv injection of guta ion. And
• 28:53
  Speaker 2: of course mitochondria are also affected by sleep, and that's
• 28:56
  Speaker 2: why we go back to the importance of sleep for weight.
• 28:59
  Speaker 2: So we find that people who have shift this order,
• 29:01
  Speaker 2: who have sleep apnea, have higher rates of heart attack stroke,
• 29:05
  Speaker 2: and that's again because the mitochondria. I'd never tell us
• 29:08
  Speaker 2: in medical school why they have high rates, but now
• 29:10
  Speaker 2: we understand it's a mitochondria not working, and that's why
• 29:13
  Speaker 2: people have When they don't get enough sleep, you get
• 29:15
  Speaker 2: all kinds of health issues, So you want to support
• 29:18
  Speaker 2: your mitochondria. And they're also affected by intermittent fasting. So
• 29:21
  Speaker 2: if you skip a meal once in a while, or
• 29:23
  Speaker 2: you know, on the weekend, skip breakfast and just do brunch,
• 29:27
  Speaker 2: you're also promoting to new making new mitochondria in your cells.
• 29:34
  Speaker 1: And it's interesting when you look at the electron transport chain.
• 29:39
  Speaker 1: I mean, as well as you mentioned your lesson A,
• 29:41
  Speaker 1: you've mentioned the NAD plus. They're really important in the
• 29:44
  Speaker 1: mitochondrial transport chain. But so are B vitamins. Aren't you piquanol?
• 29:49
  Speaker 1: And this is the whole idea of we need to
• 29:52
  Speaker 1: eate that very diet so that we have all of
• 29:57
  Speaker 1: those and vitamins and cofactors, because if your electron transport
• 30:03
  Speaker 1: chain is not getting those things, it is not working
• 30:07
  Speaker 1: effectively and you're not producing energy. And as you say,
• 30:10
  Speaker 1: we need to be exercising, we need to be sleeping, well,
• 30:12
  Speaker 1: we need to mini minimize our stress because it's right
• 30:16
  Speaker 1: tarn at that cellular level, that's where the impact is,
• 30:19
  Speaker 1: isn't it.
• 30:21
  Speaker 2: Yes, And that's what I talk about in the Astious Revolution,
• 30:23
  Speaker 2: that those people in the blue zones don't take thatp tides.
• 30:28
  Speaker 2: You know, they are eating a balanced diet, whatever diet
• 30:31
  Speaker 2: they're following, what part of the world, they're eating a
• 30:34
  Speaker 2: lot of superfoods that we are missing. So that's what
• 30:36
  Speaker 2: I take it in my book to the next level
• 30:38
  Speaker 2: by promoting superfoods that promote great sale or health and
• 30:43
  Speaker 2: the exercise without going to a gem. Just it's built
• 30:46
  Speaker 2: in their daily routine. Whether in Oki now they have
• 30:48
  Speaker 2: no furnitures, they're up and down one hundred times a
• 30:51
  Speaker 2: day to the floor, or you know, or in you
• 30:55
  Speaker 2: know in Sardinia where they have a lot of hills
• 30:58
  Speaker 2: and they just walk. They do their tensiles a step
• 31:00
  Speaker 2: without having a bit watch or Apple watch the counter steps.
• 31:04
  Speaker 2: So yes, so it comes down to basic. But I
• 31:06
  Speaker 2: think also we live in the Western world and that's
• 31:10
  Speaker 2: why this brook is for people to give them that
• 31:13
  Speaker 2: great edge that you don't have access to great food.
• 31:16
  Speaker 2: These are the things that you need to do as well.
• 31:18
  Speaker 2: So you know, supplementation is kind of an insurance. You know, ubiquin,
• 31:22
  Speaker 2: all PIQQ, all that stuff for the micochondria ned you know,
• 31:27
  Speaker 2: red light, there's all those things. This is the advances
• 31:30
  Speaker 2: in medicine to understand how these people live. To be
• 31:32
  Speaker 2: one hundred. So those are the things that doctors can
• 31:35
  Speaker 2: help to make people make that transition to make their
• 31:39
  Speaker 2: selves work better.
• 31:41
  Speaker 1: So you mentioned the red light, and let's talk about
• 31:45
  Speaker 1: let's talk about red and near infra red light. I
• 31:49
  Speaker 1: actually have a panel I think I think that this
• 31:52
  Speaker 1: is very underappreciated, and particularly if we come back to
• 31:57
  Speaker 1: the mitochondria. You know that this red and near infra
• 32:00
  Speaker 1: red light, So the red lights grip your skin. The
• 32:03
  Speaker 1: near infrared penetrates into the skin and stimulates cytochromes, oxygen
• 32:09
  Speaker 1: is in the mitochondria, so it's a potent stimulator of
• 32:13
  Speaker 1: mitochondrial function. And we're starting to see an eye and
• 32:18
  Speaker 1: research emerging about the benefits of red and near infra
• 32:21
  Speaker 1: red light, and for particularly near near infra red for
• 32:25
  Speaker 1: things like neurodegenerative diseases as well. So what's your tick
• 32:30
  Speaker 1: on red and near infra red light? Are you a
• 32:33
  Speaker 1: bigger bond as mas?
• 32:35
  Speaker 2: I do it every weekend, I go my whole GODI.
• 32:39
  Speaker 2: So yeah, and they're also not only for the mitochondria.
• 32:42
  Speaker 2: I mean, we know the benefits for good looking skin,
• 32:46
  Speaker 2: but they also can help also to make the stostron.
• 32:50
  Speaker 2: You know, if you you know suppose we haven't another
• 32:57
  Speaker 2: we have another epidemic in the Western world where we
• 32:59
  Speaker 2: have lot of stostrone and men. You know, that's because
• 33:02
  Speaker 2: we're not and that's also affects longevity. And that's because
• 33:06
  Speaker 2: of all the processed food. You know, now we have
• 33:09
  Speaker 2: many shops opening, legalization of pot stress, all those things,
• 33:14
  Speaker 2: lowered testosterone and holding their alcohol and processed food. So
• 33:18
  Speaker 2: red light is great as well for to boost the
• 33:21
  Speaker 2: stostrol level.
• 33:23
  Speaker 1: It's interesting I heard a start the other day and
• 33:25
  Speaker 1: now I haven't I haven't tug into the research at
• 33:28
  Speaker 1: paper around it, but that that basically men's testosterone. I
• 33:34
  Speaker 1: can't I think it was in the United States? Is
• 33:36
  Speaker 1: it about half the levels on average that it was
• 33:39
  Speaker 1: fifty years ago? Is that? Is that true? Is it
• 33:42
  Speaker 1: that garden?
• 33:43
  Speaker 2: I also talked in my book about hormone replacement for
• 33:47
  Speaker 2: men for testosterol placement therapy, and I talk about bioidentical
• 33:51
  Speaker 2: hormone replacement for women. Tystostrone goes down because we're not
• 33:55
  Speaker 2: eating a lot of food that supports dystostone. We're missing
• 33:59
  Speaker 2: vitamin DAN the United States and many parts of the
• 34:01
  Speaker 2: country because of the sun, so you need vitamin d
• 34:04
  Speaker 2: to build the stostron or missing the butter again that
• 34:07
  Speaker 2: saturated fat or need to make theystostrom stress lowers, they
• 34:11
  Speaker 2: stostron alcohol lowers, the stostron obesity when you are gaining weight,
• 34:16
  Speaker 2: the dystost aromatization, plastics as well, and all that stuff. Yeah,
• 34:22
  Speaker 2: so as a result, people are gaining weight, they have
• 34:25
  Speaker 2: less sex drive, they're dating less. It's everything. It's everything
• 34:29
  Speaker 2: that has to do is all the effects of low testostrone. Unfortunately,
• 34:33
  Speaker 2: a lot of doctors don't even check the stostral level
• 34:35
  Speaker 2: or or you know, they may give you a pill
• 34:38
  Speaker 2: for just viagra, or you know, tell you to cut
• 34:41
  Speaker 2: your calories if you're gaining weight. But testostra has to
• 34:44
  Speaker 2: be checked to check whether you have depression, or whether
• 34:47
  Speaker 2: you're gaining weight, or whether you have low energy.
• 34:50
  Speaker 1: Or Yeah, and it's interesting and ryan the female side
• 34:55
  Speaker 1: as well. I mean, there's still some doctors out there
• 34:59
  Speaker 1: that think kehr T causes breast cancer, and that has
• 35:03
  Speaker 1: been burnly debunked. If it's bioidentical, bioidentical hormones actually, well,
• 35:09
  Speaker 1: can you talk about the difference between the bioidentical hormones
• 35:13
  Speaker 1: and the stuff that used to be used. Where the
• 35:15
  Speaker 1: big skur came around hormones, replacement therapy and breast cancer
• 35:21
  Speaker 1: in women.
• 35:22
  Speaker 2: So you're dealing with a study back from two thousand
• 35:24
  Speaker 2: and two that show that using synthetic hormone are linked
• 35:30
  Speaker 2: to breast cancer, stroke, and heart attack. Because those hormones
• 35:34
  Speaker 2: are synthetic, they come from pregnant horses. That's why it's
• 35:37
  Speaker 2: called premarin pregnant male urine. So they take those horses
• 35:40
  Speaker 2: in Canada where the horse, they take the progesterone and
• 35:43
  Speaker 2: they put it in a pill for women and they
• 35:45
  Speaker 2: take it domen feel better, the hot flashes and that
• 35:47
  Speaker 2: spots go away. But then the progester from the horse
• 35:50
  Speaker 2: is different than the progesterone in humans, So do women
• 35:53
  Speaker 2: start to have heart attack, stroke and breast cancer? Bioidentical
• 35:56
  Speaker 2: hormones are from yams, so even though they're from yms,
• 36:00
  Speaker 2: but they're identical to human hormones. And that happened as
• 36:04
  Speaker 2: the results of the study, many women are interested in
• 36:07
  Speaker 2: getting on hormone replacements, so the drug companies started making
• 36:11
  Speaker 2: now natural hormone. They started making estradul which is similar
• 36:14
  Speaker 2: to natural estrogen, and progesterone similar to natural progesterone, but
• 36:20
  Speaker 2: you want to do it in the right amount because
• 36:22
  Speaker 2: even when they're natural, they can cause a problem. Just
• 36:24
  Speaker 2: like contraceptive pills. You always want to upput estrogen or
• 36:28
  Speaker 2: pose estrogen with progesterone. You just want to take estrogen alone.
• 36:31
  Speaker 2: So it has to be done when a doctor understands
• 36:34
  Speaker 2: about bioidentical hormones.
• 36:36
  Speaker 1: Yeah, and also talk about the importance of testosterone in
• 36:39
  Speaker 1: women as well, because so I would say everybody gets
• 36:42
  Speaker 1: it in men, but let's talk about the role of
• 36:44
  Speaker 1: testosterone in women.
• 36:46
  Speaker 2: Yeah, so women make estrogen progesterone, but they make tiny,
• 36:50
  Speaker 2: tiny amounts of testosterone and that's also linked to their
• 36:53
  Speaker 2: sex drive and libido. And again, as women hit menopause
• 36:57
  Speaker 2: or if they have a hormonal prodroblem, they may have
• 37:01
  Speaker 2: no libido related to low testosterone. So they may have
• 37:04
  Speaker 2: to get a little bit of distosterone, very tiny dose
• 37:06
  Speaker 2: every single day as a cream to boost the stosterl level.
• 37:09
  Speaker 2: And I took in my books that believe or not,
• 37:11
  Speaker 2: there's not a single drug on the market to boost
• 37:13
  Speaker 2: the stosterol and women in the pharmacies as if like
• 37:16
  Speaker 2: libidos should not exist in women, so they always have
• 37:19
  Speaker 2: to get it from compounded pharmacy versus a regular pharmacy
• 37:23
  Speaker 2: that makes you know those hormones. So women have to
• 37:28
  Speaker 2: find a compounded pharmacy and a doctor understand the importance
• 37:30
  Speaker 2: of thestosterone to make small amounts, to take small amounts
• 37:33
  Speaker 2: every day, and to have their libido back.
• 37:36
  Speaker 1: Okay, so we talked about hormones. I think the last
• 37:40
  Speaker 1: thing I want to talk about a man in testosterone.
• 37:44
  Speaker 1: I mean, I see what I believe is a bit
• 37:47
  Speaker 1: of a concerning trend with young men going on testosterone
• 37:53
  Speaker 1: replacement therapy. Because my view on this, and correct me
• 37:57
  Speaker 1: if I'm wrong, is that once you're on TRT, you're
• 38:01
  Speaker 1: on TRT and you're on TRT for the rest of
• 38:05
  Speaker 1: your life. I mean, that's why for me, I view
• 38:08
  Speaker 1: it as something that for me will be in the
• 38:11
  Speaker 1: future when my testosterone drops to a certain level and
• 38:14
  Speaker 1: I starting to feel the effects. But for a thirty
• 38:18
  Speaker 1: year old bloke who just wants to go on TRT
• 38:23
  Speaker 1: without doing the work on losing the weird and exercising
• 38:27
  Speaker 1: and all of them needing a good diet and just
• 38:29
  Speaker 1: thinking I'm just going to take TRT and it'll be good,
• 38:32
  Speaker 1: is there a problem with that in your view, of course.
• 38:36
  Speaker 2: And that's why Stroyd's got a bad rap is because
• 38:38
  Speaker 2: of all the athletes and the body builders are abusing
• 38:41
  Speaker 2: the stostron. They buy it from the black market and
• 38:44
  Speaker 2: they're injecting themselves, and without a doctor's supervision, they can
• 38:48
  Speaker 2: run into problem. They will look great, they'll have a
• 38:51
  Speaker 2: lot of muscle, they have a lot of energy. But
• 38:53
  Speaker 2: then what happens is the body slows down the production
• 38:56
  Speaker 2: of the stostron to the testicle strength. Yes, and now
• 38:58
  Speaker 2: they're dependent on the stost And then if you do
• 39:00
  Speaker 2: it without medical supervision, not only your testosterone is a
• 39:05
  Speaker 2: total body hormone, it's not just a sex hormone. So
• 39:08
  Speaker 2: you start making too much red blood cells. The bone
• 39:10
  Speaker 2: marrow mix to me red blood cells. So think of
• 39:12
  Speaker 2: a street with too many cars. So now there's more accidents.
• 39:17
  Speaker 2: So now the red is to me red blood cells
• 39:19
  Speaker 2: in the circulation. They can have stroke, they can have
• 39:21
  Speaker 2: a heart attack, and without medical supervision, you don't know
• 39:25
  Speaker 2: what your your red blood cells are. And that's a problem,
• 39:29
  Speaker 2: and that's a risk to die early versus live longer.
• 39:33
  Speaker 1: Yeah, yeah, for sure. So if we take somebody, let's
• 39:37
  Speaker 1: take a theoretical. So you got somebody comes into your office,
• 39:40
  Speaker 1: he's thirty year old, he's overWe it, he's not exercising, diets, crap,
• 39:46
  Speaker 1: he's on his testosterone is low, and he has these symptoms.
• 39:51
  Speaker 1: Is there a use case for this person going on
• 39:56
  Speaker 1: a small dose of testosterone for a period of time
• 39:59
  Speaker 1: to help kick startup and then nan he does the
• 40:03
  Speaker 1: other behaviors and then can ty trate at that time
• 40:05
  Speaker 1: and potentially come off at again. Have you seen that?
• 40:09
  Speaker 1: Or is that thirty year old going to be on
• 40:11
  Speaker 1: testosterone for the rest of their life once they go on.
• 40:14
  Speaker 2: Every patient is different, depends upon their lifestyle, if they're
• 40:17
  Speaker 2: married or not, if they want to have children or not,
• 40:20
  Speaker 2: if they are doing everything correctly or not. And there
• 40:22
  Speaker 2: are other options other than TRT. You can put them
• 40:25
  Speaker 2: on things to simulate their own production of tystostron, whether
• 40:29
  Speaker 2: in klomithine or ACG or you know, to get their
• 40:33
  Speaker 2: own production going, optimizing the vitamins level the vitamin D,
• 40:38
  Speaker 2: giving them supplements like zinc to support the stostrum production.
• 40:42
  Speaker 2: There are supplements you can buy over the counter from
• 40:45
  Speaker 2: a vitamin shop to boost distost and I've seen them
• 40:47
  Speaker 2: work a lot dealing with stress level, lowering the alcohol
• 40:50
  Speaker 2: level to prevent the automatization of the stostrum to estrogen.
• 40:54
  Speaker 2: Maybe I put them on little dolls till they get
• 40:56
  Speaker 2: motivated and lose weight. Maybe on a GLP. So it
• 40:59
  Speaker 2: depends upon every single person. But you know, people have
• 41:04
  Speaker 2: to do everything correctly. And that's why I write books,
• 41:08
  Speaker 2: work on flags and just giving a script and just
• 41:10
  Speaker 2: go home.
• 41:11
  Speaker 1: But yeah, and it is that thing that there is
• 41:13
  Speaker 1: There's no magic pill is there that you can just
• 41:17
  Speaker 1: you can take this pill and you don't have to
• 41:19
  Speaker 1: worry about the lifestyle. That's not the way that our
• 41:22
  Speaker 1: bodies work. But you mentioned something that actually I've never
• 41:26
  Speaker 1: talked about this in the podcast, and I know that
• 41:28
  Speaker 1: we have to we have to let you go soon.
• 41:30
  Speaker 1: But I do want to talk about the GLP ones,
• 41:32
  Speaker 1: right because I mean, they're all over the place now.
• 41:35
  Speaker 1: I so your view on the g LP ones, like
• 41:41
  Speaker 1: what is what is good about them? And what do
• 41:45
  Speaker 1: we need to be aware of on those GLP ones
• 41:49
  Speaker 1: and is there any signal concerning thing that's buried in
• 41:55
  Speaker 1: the noise at the minute. I mean, I'm seeing research papers.
• 41:58
  Speaker 1: GLP wants do this, they do that, they did the
• 42:00
  Speaker 1: other thing, and some of the effects are amazing, but
• 42:04
  Speaker 1: talk us through the pros and also some of the
• 42:08
  Speaker 1: cons that maybe people aren't thinking apart.
• 42:12
  Speaker 2: I think GLP drugs are great for somebody who tried
• 42:16
  Speaker 2: everything to lose weight and they cannot lose weight. And
• 42:19
  Speaker 2: I have some patients who oppose it. They say, I
• 42:20
  Speaker 2: don't want to be on a drug. But people have
• 42:23
  Speaker 2: to understand. When we eat, we say create a GLP
• 42:26
  Speaker 2: and the GLP goes to our brain. They tell us
• 42:28
  Speaker 2: we are full. The only difference between the GLP drugs
• 42:31
  Speaker 2: and the hormone we make in our bodies is it
• 42:34
  Speaker 2: stays in the body for four hours and it's time
• 42:36
  Speaker 2: for lunch. Then we have lunch, then after four hours
• 42:39
  Speaker 2: it's time for dinner. The GLP, the molecule stays in
• 42:42
  Speaker 2: the body for a week, so it is natural. But
• 42:47
  Speaker 2: the problem is people don't want to change their lifestyle
• 42:49
  Speaker 2: because really what you're doing is you're just tricking your
• 42:52
  Speaker 2: body that you're not hungry. You're eating less, so there
• 42:55
  Speaker 2: are some side effects. So you really have to push
• 42:58
  Speaker 2: yourself to eat protein because if you don't eat enough
• 43:00
  Speaker 2: protein for your body, you're gonna lose muscle, not just
• 43:03
  Speaker 2: the fat, and you have to do strength training. If
• 43:05
  Speaker 2: you're not willing those two things, that's going to be
• 43:07
  Speaker 2: dangerous where you're going to have not only muscle loss
• 43:11
  Speaker 2: as you get older, and you want to have muscle
• 43:14
  Speaker 2: as you get older, but you also can have if
• 43:16
  Speaker 2: you're eating pizza on a GLP slats of pizza instead
• 43:19
  Speaker 2: of three, you're also going to have vitamin deficiency. You're
• 43:22
  Speaker 2: gonna have bone loss. We've heard of people having hair loss,
• 43:27
  Speaker 2: very rare, but it happens. I had one patient who
• 43:29
  Speaker 2: had hair loss. So people have to do it correctly.
• 43:32
  Speaker 2: But there are a lot of benefits for the GLP
• 43:34
  Speaker 2: now we know they prevent heart attack, they prevent strokes,
• 43:37
  Speaker 2: they have longevity, they help with sleep apnea, they help
• 43:41
  Speaker 2: with sugar level, they help use diabetes, and the newest
• 43:44
  Speaker 2: thing is about reduction of breast cancer and colon cancer.
• 43:47
  Speaker 2: So there are a lot of benefits to them. But
• 43:50
  Speaker 2: I think also it's part of our magic formula to
• 43:54
  Speaker 2: a longer life that you have to do everything correctly.
• 43:56
  Speaker 2: You can just eat right and think that you'll be okay.
• 44:00
  Speaker 2: You could eat right, and but you also have to exercise.
• 44:02
  Speaker 2: You have to also address your sleep. And you know,
• 44:05
  Speaker 2: and I think the supplements, the medication that peptides are
• 44:08
  Speaker 2: insurance in Australia and the United.
• 44:11
  Speaker 1: States, Yes, indeed. And but that it's interesting that the
• 44:16
  Speaker 1: gopis is that because some people can't tolerate the side
• 44:21
  Speaker 1: effects right, particularly after a while, right and around the.
• 44:26
  Speaker 2: Constigation and all that stuff. I mean they paralyzed a
• 44:29
  Speaker 2: whole and tested and not just your stomach. So people
• 44:32
  Speaker 2: can be constipated through days. They can have heartburn, they
• 44:35
  Speaker 2: can have reflux. So that's why you have to start slow.
• 44:38
  Speaker 2: But their newer g LP, we have a new GLP
• 44:41
  Speaker 2: is going to come next year right at RETIEFLG that's
• 44:44
  Speaker 2: going to be so miraculous. Is going to be the semaglutide,
• 44:47
  Speaker 2: and that there's appetite by a whole lot. The research
• 44:50
  Speaker 2: is very promising.
• 44:51
  Speaker 1: There's I saw that there's some early scale trials going
• 44:55
  Speaker 1: on at the minute, Michael, that they are combining a
• 44:59
  Speaker 1: geo pay with a mile statin inhibitor. And the early
• 45:05
  Speaker 1: stuff was like they were losing with it and not
• 45:08
  Speaker 1: losing muscle. I'm like, holy shit. So that's a top pie.
• 45:12
  Speaker 2: That's a top pie that is not efty approved and
• 45:14
  Speaker 2: somebody builders are using that. Yes, you know, I think
• 45:18
  Speaker 2: the sky is the limit right now with all the
• 45:20
  Speaker 2: research we have and all the information we have. That's
• 45:23
  Speaker 2: why this book is called The Age's Revolution, because I
• 45:26
  Speaker 2: feel that I need to promote this information for everybody
• 45:28
  Speaker 2: to know what the mitochondria do, what anyda is, what
• 45:32
  Speaker 2: clean eating is, what's the hormones, what did istosterone? And
• 45:36
  Speaker 2: you have to address aging from all the angles, address
• 45:39
  Speaker 2: all the hallmarks. And that's why I feel a revolution
• 45:41
  Speaker 2: is coming from young people because they're really interested in
• 45:44
  Speaker 2: healthcare and they're not interested in getting sick like our
• 45:47
  Speaker 2: parents and grandparents. We don't want to be sixty year
• 45:50
  Speaker 2: old with too heart attack and a stroke. I want
• 45:52
  Speaker 2: to be a ninety year old and active.
• 45:55
  Speaker 1: Yeah. The last question, very last question to you, Michael,
• 46:00
  Speaker 1: peptide half part two. Yeah, yeah, I think we might
• 46:03
  Speaker 1: have to so the bos on the same.
• 46:04
  Speaker 2: Way as now that you know parts of my book.
• 46:07
  Speaker 1: Yeah, let's very quickly just just talk about peptides. I
• 46:13
  Speaker 1: mean the regulatory status. I think it's changing in the
• 46:17
  Speaker 1: United States around I think about a dozen peptides. I'm
• 46:20
  Speaker 1: not sure if it's already in in Australia. Peptides are
• 46:24
  Speaker 1: not approved for use, right, so the people who are
• 46:27
  Speaker 1: taking it in Australia are buying the for research purposes
• 46:32
  Speaker 1: only peptides and using them themselves. An interesting little aside
• 46:37
  Speaker 1: on this just could because a lot of people in
• 46:39
  Speaker 1: the fitness industry are doing this. I've seen a lot
• 46:42
  Speaker 1: of people who are now taking peptides that they're buying
• 46:46
  Speaker 1: on the internet, on the black market or the gray
• 46:49
  Speaker 1: market on the Internet that would not take the COVID
• 46:53
  Speaker 1: vaccine because they were saying, I don't know what shit
• 46:56
  Speaker 1: is in that and whether it's safe, And yet they're
• 46:59
  Speaker 1: buying pep tides from China and the Great market. So
• 47:03
  Speaker 1: that's one thing. There's a different thing about the ones
• 47:06
  Speaker 1: that are not being approved or are approved for use
• 47:11
  Speaker 1: and buy a doctor like you prescribing them. So let's
• 47:16
  Speaker 1: talk about from that perspective. And are you excited about
• 47:22
  Speaker 1: the landscape with peptides or do you think it's over
• 47:26
  Speaker 1: hyped in general?
• 47:28
  Speaker 2: I think it's a step in the right direction. I
• 47:30
  Speaker 2: think with RFK Junior, it was very hard to get
• 47:34
  Speaker 2: many of those peptizes. In fact, some of them have
• 47:36
  Speaker 2: not come. There are peptides used in Europe, like cerebral
• 47:39
  Speaker 2: license for people with stroke and dementia that has been
• 47:43
  Speaker 2: taken off and I cannot find it anymore. It helped many,
• 47:46
  Speaker 2: many patients, so that's a problem. But it's good for
• 47:49
  Speaker 2: people to buy from pharmacies that are tested, serve partly
• 47:54
  Speaker 2: tested to make sure they're getting the right thing, because
• 47:56
  Speaker 2: if you buy online, you don't know what you're getting.
• 47:59
  Speaker 2: You may not be getting any peptides at all, are
• 48:01
  Speaker 2: you getting even the wrong dose, or you're not getting
• 48:04
  Speaker 2: even sterile peptides, which can be a risk to get
• 48:06
  Speaker 2: sepsissor as you're injecting these things in your skin and
• 48:09
  Speaker 2: in your body. You don't want to do that. So
• 48:11
  Speaker 2: I think it's a step in the right direction for
• 48:14
  Speaker 2: us to have more peptides available. And there are some
• 48:16
  Speaker 2: peptides that are FD approved, you know, all the glps
• 48:20
  Speaker 2: the summer rather than is FD approved for body from muscles.
• 48:24
  Speaker 2: Maybe myostatin is not, but we have a lot of
• 48:26
  Speaker 2: options right now. But I think now it's it's a
• 48:29
  Speaker 2: step in the right direction.
• 48:31
  Speaker 1: And what's your what's your thoughts on very very very
• 48:34
  Speaker 1: last question we talked about the mitochondria. What's your thought
• 48:37
  Speaker 1: and you mentioned mot C. What's your thoughts on that
• 48:40
  Speaker 1: is that is that a useful peptide for mitochondria function
• 48:45
  Speaker 1: or do you think it's a bit overhyped.
• 48:47
  Speaker 2: We don't have the human research right now, so we
• 48:50
  Speaker 2: only have anecdotal evidence from people who use it to
• 48:53
  Speaker 2: feel more energy. So it is used to support the
• 48:56
  Speaker 2: mitochondria to mimic the effect of exercise for people who
• 49:01
  Speaker 2: have mitochondrial dysfunction. I think that's an option, but right
• 49:05
  Speaker 2: now we don't have long term data or human studies
• 49:08
  Speaker 2: on it.
• 49:08
  Speaker 1: I think I think that's that's part of the issue,
• 49:11
  Speaker 1: isn't it, Michael, that a lot of the peptides that
• 49:13
  Speaker 1: people are are currently buying on the gray market are
• 49:16
  Speaker 1: actually not tested on humans and there's not good da
• 49:20
  Speaker 1: I mean, even take probably the most prevalent on PPC one,
• 49:25
  Speaker 1: there's not a lot of human data on that, right.
• 49:27
  Speaker 2: You know, sometimes we have research for fifty years and
• 49:29
  Speaker 2: it could be wrong. Like you have research statuate with
• 49:32
  Speaker 2: fifty years that cause heart attack. It was all wrong
• 49:35
  Speaker 2: because the situated that we'll love with trans fats. So
• 49:38
  Speaker 2: I think the problem is, you know a lot of
• 49:42
  Speaker 2: people get better on BPC, but does it have does
• 49:44
  Speaker 2: it cause a risk to have cancer. We don't know
• 49:47
  Speaker 2: that yet, so that's that's the issue. I think the
• 49:50
  Speaker 2: problem is that we're really on our own. You know,
• 49:53
  Speaker 2: the medical establishment has failed us in providing us with
• 49:57
  Speaker 2: the right information. And that's why it's like the wild West.
• 50:00
  Speaker 2: People are looking for information on their own. That's why
• 50:02
  Speaker 2: you find people on Instagram using all kinds of peptides BPC.
• 50:06
  Speaker 2: They have their own kind of like benefesta of what
• 50:10
  Speaker 2: to take. And that's not a good thing too. But
• 50:12
  Speaker 2: I think it's because we're on our own. We have
• 50:15
  Speaker 2: to get our own information because some of the guidelines
• 50:18
  Speaker 2: are wrong.
• 50:19
  Speaker 1: I think that that is a very good point for
• 50:21
  Speaker 1: us to end on. Is that. And and particularly since
• 50:25
  Speaker 1: COVID and the trust in the medical fraternity, like in Australia,
• 50:32
  Speaker 1: and just because of the stuff that happened in COVID,
• 50:34
  Speaker 1: the trust in the medical profession really really plummeted. And
• 50:40
  Speaker 1: as you say, people are now going out and they're
• 50:42
  Speaker 1: getting their health information from people like podcasters or are
• 50:47
  Speaker 1: trusted as much, if not more than health professionals, which
• 50:50
  Speaker 1: is freaking crazy, right, But I think it.
• 50:53
  Speaker 2: Sounds you sounds like you know a lot, and that's
• 50:55
  Speaker 2: why I say in my books that I'm a physician.
• 50:58
  Speaker 2: I never thought in my life that I went to
• 51:01
  Speaker 2: medical school to become an author, So I'm an accidental author.
• 51:06
  Speaker 2: I just wanted to be a doctor, and all of
• 51:09
  Speaker 2: a sudden, I'm on TV talking about things and correcting
• 51:12
  Speaker 2: government guidelines and correcting Harvard, which is insane to say,
• 51:16
  Speaker 2: you know, but I had to do it because I
• 51:19
  Speaker 2: feel the people were lost and I cannot spend ten
• 51:22
  Speaker 2: hours at each patient tell them all the information. Look
• 51:26
  Speaker 2: how much we have covered in that podcast, and there's
• 51:28
  Speaker 2: still a lot to talk about. So that's how my
• 51:30
  Speaker 2: books can help people in the outside world beyond my
• 51:33
  Speaker 2: office space.
• 51:34
  Speaker 1: Very cool. And so where do we send people, Michael
• 51:37
  Speaker 1: to get copies, whether they're interested in The Perfect ten
• 51:40
  Speaker 1: Diet or The Ages Revolution book, where do we send
• 51:44
  Speaker 1: them to?
• 51:46
  Speaker 2: My books are published in many countries and in different languages,
• 51:48
  Speaker 2: so they can always go to Amazon or any bookseller.
• 51:51
  Speaker 2: They'll find them there. They can also Google me. Yeah,
• 51:53
  Speaker 2: my books are or everywhere where books are sold.
• 51:56
  Speaker 1: And your website, Michael for because there's a heap of
• 51:58
  Speaker 1: stuff on your website, Well.
• 52:01
  Speaker 2: My website for my office is Michael Diss, MD, dot.
• 52:04
  Speaker 1: Com, Michael iss MD dot com, and the two books
• 52:08
  Speaker 1: that you want to be ordering are The Perfect Ten
• 52:10
  Speaker 1: Diet and the more recent The Ageless Revolution by doctor
• 52:16
  Speaker 1: Michael is Ease. Michael, thank you very much for for
• 52:19
  Speaker 1: your time and your expertise and and sharing that with
• 52:22
  Speaker 1: our listeners.
• 52:23
  Speaker 2: It was great talking to you.
• 52:24
  Speaker 1: Awesome Thanks mac h