EP 71: HRT, Peptides & GLP-1s: What Women Need to Know About Menopause | Karen Martel |

The Loop Podcast: Peptides, Longevity & Women’s Wellness · Sep 17, 2026 · 1h 2m · transcript

Karen Martel, CEO of Midlife Solutions, joins Stephanie Gambetta for a candid conversation about perimenopause, menopause, hormone replacement therapy, peptides, GLP-1s, and what actually changes in a woman’s body during midlife. Karen shares how her own experience being pushed into early menopause at 42 changed the direction of her career, despite already working as a nutritionist and doing everything she thought was “right.” She and Stephanie break down the early signs of perimenopause, progesterone and estrogen loss, stubborn midlife weight gain, brain fog, mood changes, and why you can’t…