Shows / Cardio Pod: Heart of the Matter
Cardio Pod: Heart of the Matter
Introducing Heart of the Matter Cardio Pod. High-level conversations to foster conversation, collaboration, and communication around the ecosystem of cardiovascular research.
Episodes
Cardio Pod: Heart of the MatterThe Stories behind the People with Dr. Barry Greenberg
In this episode, Dr. Christopher O’Connor sits down with Dr. Barry H. Greenberg for a conversation that goes beyond medicine, exploring his journey as both a…
Cardio Pod: Heart of the MatterThe Stories behind the People with Dr. Mariell Jessup
In this episode of The Stories Behind the People, Dr. Christopher O’Connor sits down with Dr. Mariell Jessup for a candid conversation about her journey, the…
Cardio Pod: Heart of the MatterPatient-Reported Outcomes as End Points in Heart Failure Trials
How can patient-reported outcomes help us better understand what matters most to patients with heart failure? In this episode, we take a closer look at the…
Cardio Pod: Heart of the MatterThe Stories behind the People with Dr. Clyde Yancy
In this episode of The Stories Behind the People, host Dr. Christopher O'Connor welcomes Dr. Clyde Yancy for an intimate conversation that goes beyond clinical…
Cardio Pod: Heart of the MatterSurrogate Clinical Outcomes and Expanded Endpoints: point/counterpoint.
In this episode, we explore the evolving role of surrogate clinical outcomes and expanded endpoints in heart failure research, featuring a point/counterpoint…
Cardio Pod: Heart of the MatterHow to leverage natural history cohorts for regulatory purposes?
In this episode, host Dr. Christopher O'Connor sits down with Drs. Barry Greenberg, Marvin Konstam, and Jim Carr to discuss how to leverage natural history…
Cardio Pod: Heart of the MatterThe Stories Behind the People with Dr. Robert Califf
In this inaugural episode of The Stories Behind the People, host Dr. Christopher O'Connor sits down with Dr. Robert Califf for a candid conversation that goes…
Cardio Pod: Heart of the MatterCKM Score
In this episode, host Dr. Christopher O'Connor is joined by Dr. Carine Hamo, Dr. Ankeet Bhatt, and Dr. Javed Butler to discuss the CKM Score and the…
Cardio Pod: Heart of the MatterEvaluating and Accounting for Body Weight and Obesity / Adjusting for Body Weight
In this episode, host Dr. Christopher O'Connor is joined by Drs. Carine Hamo, Ankeet Bhatt, Joan Lindenfeld, and Martin Cowie to discuss the importance of…
Cardio Pod: Heart of the MatterDerisking Phase II Clinical Trials in HF
In this episode, host Christopher O'Connor sits down with Scott D. Solomon, Ellis Unger, Janet Wittes, Michael Felker, Ben Saville, Douglas Mann, and Fady…
Cardio Pod: Heart of the MatterClass Effect considerations in devices
In this episode, Host Dr. Christopher O'Connor and his guests, Dr, Joann Lindenfeld, Dr. Mitchell Psotka, Dr. Minnow Walsh and Dr. William Abraham, discuss…
Cardio Pod: Heart of the MatterCrossover designs and event driven trials in devices
In this episode, host Christopher O’Connor and his colleagues discuss device trials and how they differ from drug trials. The conversation focuses on how…
Cardio Pod: Heart of the MatterBest Practices for Site-Based Research (Part 3)
Host Christopher O’Connor, MD is joined by Jana Svetlichnaya, MD; Anu Lala-Trindade, MD; and Marshall Brinkley, MD to unpack the challenges of site-based…
Cardio Pod: Heart of the MatterRecurrent Events VS. Time to First Event Analysis
This episode explores two different ways of analyzing outcomes in clinical trial and longitudinal studies in cardiovascular and heart failure research.
Cardio Pod: Heart of the MatterThe Role of Using Data from Real World Evidence to Inform Regulatory Applications
In this episode, host Dr. Christopher O'Connor sits down with Dr. Robert Califf, MD, Nicholaas Honig, JD, Dr. Maria Rosa Costanzo, and Dr. Norman Stockbridge…
Cardio Pod: Heart of the MatterSocial Drivers of Health
In this episode, Christopher O’Connor, MD, sits down with Melvin Echols, MD; JoAnn Lindenfeld, MD; Minnow Walsh, MD; and Wayne Batchelor, MD to explore the…
Cardio Pod: Heart of the MatterBest Practices for Site-Based Research (Part 2)
This episode discusses further the challenges of site-based research. What goes into those barriers, obstacles, and opportunities to be a successful site-based…
Cardio Pod: Heart of the MatterModels of Success in Site-Based Research
In this episode, Host Dr. Christopher O’Connor is joined by Dr. Melvin Echols, Dr. Anu Lala-Trindade, Dr. Maria Rosa Costanzo, Dr. Lars Kober, and Dr. Norman…
Cardio Pod: Heart of the MatterWhy is Site-Based Research Broken in the United States?
Hosted by Christopher O’Connor, MD, this episode dives into why site-based research is “broken” — fragmented, inefficient, and weighed down by administrative…
Cardio Pod: Heart of the MatterRepresentation vs. Diversity in Clinical Trials
In this episode, host Dr. Christopher O’Connor is joined by Dr. Christian Guilliod, Dr. Wayne Batchelor, Dr. Mona Fiuzat, and Dr. Orly Vardeny to discuss the…
Cardio Pod: Heart of the MatterShould Investigators Have Access to Trial Data?
In this episode, Host Christopher O’Connor, MD, is joined by Robert Califf, MD; Michael Bristow, MD; Scott Solomon, MD; Marvin Konstam, MD; and Mona Fiuzat…
Cardio Pod: Heart of the MatterHow Can AI Enhance Recruitment in Clinical Trials?
In this episode, experts Jonathan Cunningham, MD; Ankeet Bhatt, MD; Trejeeve Martyn, MD; Anu Lala-Trindade, MD; Sneha Shah Jain, MD; Elise Shalowitz, MS; and…
Cardio Pod: Heart of the MatterStandardized Definitions of Changes in Kidney Function in Trials of Heart Failure
Only with cardiology with nephrology working together can the field of acute decompensated heart failure move forward with respect to kidney related entry…
Cardio Pod: Heart of the MatterThe Role of AI in the Future of Clinical Trials and Therapeutic Development
How can artificial intelligence enhance and augment clinical trials? In what ways can it be used responsibly to increase trial efficiency? Host Chris O'Connor…
Cardio Pod: Heart of the MatterImportance of Subgroups in Heart Failure Clinical Trials - Part 2
Host Dr. Christopher O'Connor invites Drs. Scott Solomon, William Abraham, JoAnn Lindenfeld, Brian Claggett, Mona Fiuzat, and Mitchell Psotka to continue…
Cardio Pod: Heart of the MatterImportance of Subgroups in Heart Failure Clinical Trials - Part 1
Host Dr. Christopher O'Connor invites Drs. Javed Butler, Mariell Jessup, and Mitchell Psotka to discuss the importance of subgroups in heart failure clinical…
Cardio Pod: Heart of the MatterDSMB Training Academy: Preparing the Next Generation (Part 2)
Dr. Christopher O'Connor interviews the founding members of the data safety monitoring board (DSMB) training team, Dr. David DeMets, Dr. Janet Wittes, and Dr…
Cardio Pod: Heart of the MatterDSMB Training Academy: Preparing the Next Generation of Members (Part 1)
Drs. Janet Wittes, Mona Fiuzat, Maria Rosa Costanzo, Ana Barac, Barry Greenberg, Vanessa Blumer, and Michael Bristow come together on this episode with Dr…
Cardio Pod: Heart of the MatterAre we making progress with the recruitment of women in heart failure trials?
Drs. Mariell Jessup, JoAnn Lindenfeld, Maria Rosa Costanzo, Mona Fiuzat, Bill Abraham, and Wayne Batchelor join Christopher O'Connor to discuss the recruitment…
Cardio Pod: Heart of the MatterImplications of the Advisory Committee Meetings for the Heart Failure Community
Drs. Peter Carson, JoAnn Lindenfeld, John Teerlink, Orly Vardeny, and Bill Abraham join Dr. Christopher O'Connor to discuss the implications of the FDA…
Cardio Pod: Heart of the MatterDiversity in Heart Failure Clinical Trials
Special guests Melvin Echols, Nasrien Ibrahim, Vanessa Blumer, Wayne Batchelor, JoAnn Lindenfeld, and Mitchell Psotka join the podcast to discuss the…
Cardio Pod: Heart of the MatterThe Intersection of Heart Failure and the Kidney
James Januzzi, Maria Rosa Costanzo, John Teerlink, Marv Konstam, Bill Abraham, and nephrologist Steven Coca join the podcast to discuss HF and AKI. How should…
Cardio Pod: Heart of the MatterStatistical Considerations in Heart Failure Research
Janet Wittes, Eric Leifer, Bill Abraham, and Mitchell Psotka join the podcast to discuss all-things statistics. What is an estimand? How should we treat…
Cardio Pod: Heart of the MatterContemporary Challenges in HF Clinical Trial Design
Expert statisticians Janet Wittes and Eric Leifer join the podcast to discuss hazard ratios, the phenomenon of "hazard ratio drift", and other contemporary…
Cardio Pod: Heart of the MatterWhat is the Heart Failure Collaboratory?
Join Drs. Christopher O'Connor, JoAnn Lindenfeld, Mitchell Psotka, Scott Solomon, Mona Fiuzat, Bill Abraham, and Peter Carson as they introduce a novel concept…