Shows / Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
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Episodes
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Dexmedetomidine Pharmacology
Dexmedetomidine is a selective alpha-2-adrenergic agonist with sedative characteristics. Dexmedetomidine is commonly used in ICU and procedural sedation, as…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Calcitonin Pharmacology
On this episode, I discuss the pharmacology of calcitonin. Calcitonin has an indication for osteoporosis as well as hypercalcemia. When considering drug…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Rivastigmine Pharmacology
Rivastigmine is an acetylcholinesterase inhibitor used in the management of certain dementias. I discuss rivastigmine pharmacology on this episode. Weight loss…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Caffeine Pharmacology
Caffeine is a commonly used supplement and is found in many food and beverages. I discuss caffeine pharmacology, adverse effects, and drug interactions…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Colestipol Pharmacology
Colestipol is a bile acid sequestrant that can be used in the management of hyperlipidemia. By binding bile acid in the gut, colestipol can lower LDL that is…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Metolazone Pharmacology
Metolazone (Zaroxolyn) is a thiazide-like diuretic. It promotes the loss of water and sodium through the kidney. The most common indication I see metolazone…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Ibandronate Pharmacology
Ibandronate is a bisphosphonate that can be used in the management of osteoporosis. Bisphosphonates like ibandronate require a full glass of water for oral…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Fluticasone, Umeclidinium, and Vilanterol Pharmacology
Fluticasone, Umeclidinium, and Vilanterol is a combination medication used in the setting of COPD. I discuss the pharmacology of this agent further in this…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Hyoscyamine Pharmacology
Hyoscyamine is an anticholinergic medication that is primarily used for GI problems like spasms and pain associated with IBS. Because of the highly…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Calcium Acetate Pharmacology
Calcium Acetate (PhosLo) is used in the management of hyperphosphatemia associated with CKD. Important monitoring parameters for calcium acetate include…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Nortriptyline Pharmacology
Nortriptyline is a TCA that can be used for depression and various pain syndromes. I discuss other less common diagnoses in this podcast episode as well. There…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Hydroxychloroquine Pharmacology
Hydroxychloroquine is classified as a DMARD and when used chronically, can be helpful in managing rheumatoid arthritis and Lupus. There have been reports of…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Latanoprost Pharmacology
Latanoprost is a prostaglandin F2 analog that can help reduce intraocular pressure and manage glaucoma. Excessive eyelash growth is a potential adverse effect…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Terbinafine Pharmacology
Terbinafine can inhibit CYP2D6 which plays an important role in the metabolism of many drugs such as metoprolol, fluoxetine, and clozapine. With…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Alendronate Pharmacology
Alendronate is a bisphosphonate that is used in the management of osteoporosis. In this episode, I discuss osteonecrosis risk and what are some of the risk…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Diazepam Pharmacology
Diazepam has numerous dosage forms. There are rectal, injectable, and oral formulations of the drug that are commonly used in clinical practice. Diazepam has 2…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Dicyclomine Pharmacology
Dicyclomine is an anticholinergic agent that is used to help manage GI pain associated with IBS. Dicyclomine has a very short half-life which means that it can…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Diltiazem Pharmacology
Diltiazem is a non-dihydropyridine calcium channel blocker that can be used in atrial fibrillation as well as hypertension. One big downside to diltiazem is…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Zolpidem Pharmacology
Zolpidem enhances the action of GABA which is an inhibitor neurotransmitter. Zolpidem metabolism can be impacted by the use of CYP3A4 inhibitors…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Oral Semaglutide Pharmacology
On this episode, I discuss the pharmacology of oral semaglutide. It is a GLP-1 agonist that is the first one in the class to have an oral formulation. There is…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Probenecid Pharmacology
Patients with G6PD deficiency who are taking probenecid are at increased risk for hemolytic anemia. In a patient taking probenecid, they need to have adequate…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Nicotine Patch Pharmacology
Nicotine replacement therapy is an important tool in helping our patients quit smoking. There are lots of clinical pearls involving the pharmacology of…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Doxepin Pharmacology
Doxepin is under the class of tricyclic antidepressants. It can inhibit the reuptake of serotonin and norepinephrine. In addition to the serotonin and…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Atomoxetine Pharmacology
Atomoxetine is a norepinephrine reuptake inhibitor that can be used in the management of ADHD. Atomoxetine is a non-controlled substance option for patients…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Fluoxetine Pharmacology
Fluoxetine is an SSRI used in the management of depression, anxiety, OCD, PTSD, and other psychiatric conditions. Fluoxetine has a very long half-life which…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Metoprolol Pharmacology
Metoprolol is a beta-blocker commonly used in the management of hypertension, heart failure, and atrial fibrillation. There is an extended release dosage form…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Mometasone Pharmacology (Nasal and Oral Inhalation)
Mometasone is an inhaled corticosteroid and a nasal corticosteroid. The inhaled steroid is called Asmanex by brand name and the nasal version is Nasonex…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Methylphenidate Pharmacology
Methylphenidate has an FDA approved indication for ADHD. In this podcast episode, I cover the pharmacology, adverse effects, kinetics, and drug interaction…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Cilostazol Pharmacology
Cilostazol has antiplatelet and vasodilatory effects. Because of this, it can manage symptoms of intermittent claudication. GI upset, headache, and edema are…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Metronidazole Pharmacology
Metronidazole (Flagyl) is an antibiotic that is used for various infections. Metronidazole can certainly cause GI upset like most antibiotics, but uniquely may…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Testosterone Pharmacology
Testosterone replacement is primarily utilized in patients with hypogonadism. I discuss testosterone pharmacology, adverse effects, and drug interactions on…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Morphine Pharmacology
Morphine has opioid agonist activity that can cause respiratory depression and death in overdose. Morphine-6-glucuronide is the metabolite that can accumulate…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Prasugrel Pharmacology
Prasugrel is a P2Y12 inhibitor that is used in the setting of ACS. Be aware of patients who may be taking over the counter medications that can increase their…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Mirabegron Pharmacology
Mirabegron is a beta-3 agonist that can help relax bladder smooth muscle and manage symptoms of overactive bladder. Mirabegron inhibits CYP2D6 which can…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Erythromycin Pharmacology
Erythromycin uniquely has some potential benefit in the setting of gastroparesis. Azithromycin you will likely not see used for this indication. Erythromycin…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Naloxone Pharmacology
Naloxone is a life saving drug that can help manage an opioid overdose situation. Naloxone blocks opioids receptors so opioid agonists cannot bind there. One…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Prochlorperazine Pharmacology
Prochlorperazine has several potential mechanisms of action. It can block dopamine and alpha receptors as well as have anticholinergic effects…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Buspirone Pharmacology
Buspirone is an anti-anxiety medication that has the potential of having some serotonin agonist activity. Buspirone has a very high first-pass metabolism. This…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Ondansetron Pharmacology
Ondansetron (Zofran) is a medication used for nausea and vomiting. In this episode, I lay out the pharmacology, adverse effects, drug interactions and more!…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Acyclovir Pharmacology
On this episode “Acyclovir Pharmacology” I discuss the mechanism of action, important monitoring parameters, and drug interactions with acyclovir…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Benzodiazepine Pharmacology
Benzodiazepines act by enhancing the effect of GABA, an inhibitory neurotransmitter. Benzodiazepines can cause confusion, sedation, and respiratory depression…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Celecoxib Pharmacology
Celecoxib is easy to remember as its mechanism of action is “COX”-2 Inhibition. This can result in result in reduced prostaglandin formation and…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Oseltamivir Pharmacology
Oseltamivir is an antiviral agent that is indicated for the treatment and prophylaxis of influenza. It is important to remember that oseltamivir is cleared at…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Dolutegravir
Dolutegravir is an integrase inhibitor that is used in the management of HIV infection/ Carbamazepine along with other enzyme inducers can substantially lower…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Medroxyprogesterone Acetate Injection Pharmacology
On this podcast episode, I cover medroxyprogesterone acetate injection pharmacology (DMPA or Depo-Provera) Medroxyprogesterone acetate injection is given every…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Budesonide Formoterol Pharmacology
Budesonide/formoterol inhalation is sold under the brand name Symbicort. Budesonide/formoterol is a combination agent that is used in the management of COPD…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Benztropine Pharmacology
Benztropine is a highly anticholinergic medication that is primarily used for movement disorders. Antipsychotics can cause extrapyramidal adverse effects that…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Budesonide Pharmacology (Oral and Rectal Formulations)
Budesonide is a corticosteroid that can be given orally or rectally for management of Crohn’s disease or ulcerative colitis. Because budesonide has a…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Cimetidine Pharmacology
Cimetidine blocks histamine 2 receptors which can suppress acid production and reduce symptoms of heartburn. One of the major downsides to cimetidine is that…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Clopidogrel Pharmacology
Clopidogrel is an antiplatelet agent that is often used in combination with aspirin to help reduce the risk of an MI. The risk of bleed is a high priority with…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Sulfasalazine Pharmacology
Sulfasalazine is a medication that can be used for diseases like rheumatoid arthritis, Crohn’s disease, and Ulcerative Colitis. Because sulfasalazine can…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Cholestyramine Pharmacology
On this episode, I discuss the pharmacology of cholestyramine. Cholestyramine was originally developed as an agent to manage cholesterol, but has fallen out of…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Rifampin Pharmacology
Rifampin is classified as an antibiotic and an antituberculosis agent. It primarily works by inhibiting bacterial RNA polymerase. While not extremely common…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Heparin Pharmacology
Heparin is an interesting drug with a lot of unique clinical quirks. This drug ultimately inhibits the formation of fibrin. Fibrin is an essential component of…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Montelukast Pharmacology
On this episode, I discuss montelukast pharmacology Montelukast is a leukotriene receptor antagonist. Leukotrienes play an important role in causing…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Clozapine Pharmacology
On this episode, I discuss clozapine pharmacology. This drug has multiple mechanisms of action: Dopamine blockade, anticholinergic activity, and alpha blocking…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Carbamazepine Pharmacology
On this episode, I discuss carbamazepine pharmacology. This drug is most commonly used for seizures, bipolar disorder, or trigeminal neuralgia. Carbamazepine…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Stimulant Laxatives Pharmacology
On this episode, I discuss the pharmacology of commonly used stimulant laxatives like sennosides and bisacodyl. Stimulant laxatives “stimulate” the…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Ezetimibe Pharmacology
On this episode, I discuss ezetimibe pharmacology. Ezetimibe works by inhibiting Niemann-Pick C1-Like1 (NPC1L1) transporter. This transporter aids in…
- Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Azithromycin Pharmacology
On this episode, I cover azithromycin pharmacology. This drug primarily acts by inhibiting protein synthesis. It binds to the 50s ribosomal subunit. GI adverse…