Dexmedetomidine Pharmacology

Real Life Pharmacology - Pharmacology Education for Health Care Professionals · Jun 11, 2020 · 9m

Dexmedetomidine is a selective alpha-2-adrenergic agonist with sedative characteristics.

Dexmedetomidine is commonly used in ICU and procedural sedation, as well as postoperative pain.

A few of the more serious adverse effects of dexmedetomidine to keep an eye on including bradyarrhythmias/bradycardia and hypotension.

Dexmedetomidine undergoes hepatic metabolism, meaning a dose reduction may be required in patients with impaired hepatic function.

Major drug interactions to monitoring for with dexmedetomidine include co-administration with anesthetics, sedatives, hypnotics, and opioids, as it…