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The Showcase: Heart Health Edition — The Science of Heart Health, Prevention and Cellular Activation · Wellness Wednesday Activation Podcast

0:02
Jami: Hello, everybody, and welcome to Wellness Wednesday.
0:05
Jami: My name is Jamie Williams, and you are in for a treat tonight.
0:08
Jami: I always feel so honored to be able to use this platform to bring information, education, honestly, health empowerment to everyone that chooses to be here.
0:18
Jami: And tonight I'm going to tell you this conversation is really personal to me because I spent 13 years working as an exercise specialist in cardiac and pulmonary rehab.
0:26
Jami: And here's what I will tell you I watched firsthand what health crises could do to not only the patient, but to the people around them, to the people that support them.
0:36
Jami: I saw the fear, I saw the frustration, I saw the decline in health that sometimes people, it was too far gone that they couldn't get their health back to where they wanted it to be.
0:47
Jami: And also the financial crisis that comes with that, because being sick costs money.
0:53
Jami: I think if anybody's experienced that, it's it's way more expensive to be sick than to be healthy.
1:00
Jami: So the reason we're having this conversation tonight is because when I started to see this after 13 years, I have a very personal conversation with this because at the age of 38, my grandfather passed away from a heart attack.
1:12
Jami: At the age of 40, my father's heart disease journey started.
1:17
Jami: I'm 43 years old.
1:18
Jami: So that puts things in perspective real quickly for me.
1:21
Jami: And when I started to look at 13 years of cardiac rehab, I started to ask this question that really weighed heavy on my heart.
1:29
Jami: How can we get ahead of this?
1:31
Jami: How can we be more preventative, more proactive in the steps that we can take?
1:35
Jami: So this doesn't have to be the journey for people.
1:38
Jami: That's really what I wanted to ask the question tonight.
1:41
Jami: And I'm excited that you guys are here because, like I said, this is about empowering you, helping you make better decisions when it comes to your health.
1:48
Jami: And I think tonight, when you hear from Dr.
1:50
Jami: Doug, you're gonna walk away with a lot of golden nuggets, but you're gonna walk away with practical strategies that you can start implementing today because that's what we want Wellness to Wednesday to be about.
1:59
Jami: It's not about fear, it's not about being nervous about your health, it's really about taking the reins and taking control.
2:05
Jami: So obviously, on these Wellness Wednesdays, we'd love to talk about how activation can fit into this conversation.
2:11
Jami: And maybe that's a new concept to a lot of you that are here, but I'm always so thankful that we get the chance to share that with people because it's something that people deserve to know.
2:19
Jami: So, what you do with this information tonight is completely up to you.
2:22
Jami: But we're gonna talk about things that influence heart disease, that influence heart health, the risk factors that you want to look for, how activation fits in there as a layered approach to maybe help create an optimal environment for your body to function better.
2:38
Jami: And I'm thrilled to have Dr.
2:39
Jami: Doug Rothrock here tonight.
2:41
Jami: You guys, his his video is quite extensive, so I don't want to miss anything.
2:44
Jami: I'm probably gonna have to have him fill in the gaps.
2:46
Jami: But you guys, Dr.
2:48
Jami: Doug comes with multiple board certifications, which I think is fantastic.
2:51
Jami: We could bring him back for many conversations, and I hope that we do.
2:55
Jami: But he's an interventional cardiologist, he's board certified in cardiology, he's board certified in internal medicine, he's board certified in obesity obesity medicine and board eligible in other areas.
3:07
Jami: So, Dr.
3:08
Jami: Doug, thank you for being here.
3:10
Jami: But I would love for you to set the stage and tell us more about you.
3:14
Jami: How did you get here after 30 years of practice already?
3:18
Jami: What drew you into cardiology?
3:21
SPEAKER_00: What drew me into cardiology, I think uh, well, the intellectual challenge of cardiology back in the in the uh medical school residency days, and probably one of my best professors was a cardiologist.
3:31
SPEAKER_00: So, you know, that always leads you down the pathway of what you want to do in your life.
3:36
SPEAKER_00: But these days, after years of doing interventional cardiology and treating patients after they've already developed symptoms and are already sick, the challenge today is to try and, as you point out, prevent that.
3:48
SPEAKER_00: You know, 86% of strokes and heart attacks should be prevented.
3:53
SPEAKER_00: And unfortunately, I saw way too many people that had not dealt with prevention in their lives and and came out in the on the wrong end of the straw at the end of at the end of their lives with heart attacks and strokes and things that should really have not happened.
4:08
SPEAKER_00: It's it's there's many factors to that, and but one of the factors I think we'll see is oxidative stress and uh some of the things that we might be able to prevent or help prevent with oxidative stress.
4:21
SPEAKER_00: You know, it uh heart disease is still the number one killer in the United States and in most of the world.
4:26
SPEAKER_00: So it's an area that is so important to try and get a handle on in terms of prevention.
4:32
SPEAKER_00: Because, you know, obviously an ounce of prevention is worth a pound of of uh treatment for sure.
4:38
Jami: I appreciate that you say that because when we're talking about the the stat of being the number one killer to date, when I was in rehab, and I think you'd probably say this too, people are getting sicker quicker.
4:49
Jami: Our patients were getting younger.
4:50
Jami: It wasn't elderly people that were coming in, it was people in their 20s and 30s.
4:54
Jami: So it's a way for us to really bring more awareness.
4:57
Jami: And I want I just want to ask you this question.
4:59
Jami: You may have answered a little bit of it, but when you look at health from a preventative standpoint, what's one thing, what's something that you wish that more people understood when it comes to prevention?
5:10
SPEAKER_00: Well, I think the the probably the most important thing that I wish people would understand is you want to start earlier.
5:16
SPEAKER_00: You know, the time to start prevention is when you're in your 20s, in your 30s.
5:21
SPEAKER_00: You know, the disease, which we'll talk about a little bit later, that that takes people with heart disease and heart attacks is a 30 to 40 year disease.
5:29
SPEAKER_00: Its beginnings happen at in in the 30s, and it progresses for many, many, many years before it becomes symptomatic.
5:38
SPEAKER_00: And that's the reason I hear people all the time in my clinic or when we deal with them saying, Well, I fell fine until.
5:44
SPEAKER_00: Well, you fell fine because the disease hadn't progressed enough to really cause symptoms.
5:49
SPEAKER_00: The symptoms are a late stage of this disease.
5:52
SPEAKER_00: And so the only way to really get a handle on the late stages of the disease is to pay attention at younger ages so that you can get treatment or get lifestyle changes that help prevention in that 30 to 40 year journey of the disease.
6:07
SPEAKER_00: It's so important to start early.
6:10
Jami: It is.
6:10
Jami: It's so important to start early, and I love that you're touching on this because there's warning signs.
6:15
Jami: Like there have probably been warning signs for people, but then it became their body screaming at them, and now we have a disease.
6:20
Jami: Now we have a diagnosis because there were probably things that were happening, but a lot of us we we get so busy that we're not we're not totally tuned in to how our body truly feels.
6:30
Jami: And sometimes we just chalk it up to I'm getting older, this is normal.
6:34
Jami: So I I love that you're talking about paying attention to your body.
6:38
SPEAKER_00: And again, part of that is that the symptoms are really late stage of the disease.
6:43
SPEAKER_00: So there are ways in in modern cardiology and modern medicine to detect risk factors earlier, way earlier on in life and and deal with them before symptoms really become a s a matter of health uh for the patient.
6:59
SPEAKER_00: The the the disease is in the blood vessels.
7:02
SPEAKER_00: And so we can visualize blood vessels very well these days, and we can visualize risk factors very well these days.
7:09
SPEAKER_00: You know, you hear a lot of people who are say they only have mildly elevated cholesterol, they don't want to treat it, or they don't want to approach cholesterol treatment.
7:17
SPEAKER_00: There's many ways to treat cholesterol, there's many ways to treat blood vessel disease.
7:22
SPEAKER_00: And again, you have many opportunities to do that throughout your life, and it you should take available availability of those things.
7:30
SPEAKER_00: And one of those things, it turns out, most likely is going to be something we're going to be talking about that this company provides, which is an exciting new element in my life as a cardiologist to be able to utilize oxidative stress reduction as a uh potential bit of ammunition against the early aspects of the disease.
7:51
Jami: I love that you just said ammunition.
7:52
Jami: That is a great way to phrase that.
7:54
Jami: Because I don't want to assume that people are well-versed in understanding heart health.
7:58
Jami: So, Dr.
7:59
Jami: Doug, let's take this back for a second.
8:00
Jami: When you're talking about heightened risk of cardiovascular disease, what are some of the biggest drivers that can cause disease?
8:07
Jami: What are some of some of the biggest environmental factors or just factors that we should be paying attention to around us that influence that?
8:14
SPEAKER_00: Sure.
8:15
SPEAKER_00: You know, in the United States, of course, one of the biggest things is nutrition.
8:19
SPEAKER_00: And uh, you know, tr nutrition has not been taught well in the United States, and nutrition has fallen off the uh wagon quite a bit over the last 20 years with the obesity epidemic and the fact that people are eating too much processed food, not paying attention to the data, which suggests that the Mediterranean diet is by far the way to reduce strokes and heart attacks.
8:39
SPEAKER_00: The PREDIMED trial demonstrated a 26% reduction in stroke and heart attacks over a five-year period utilizing the Mediterranean diet.
8:47
SPEAKER_00: The low-fat, low cholesterol diet was actually a failure in terms of preventing strokes and heart attacks.
8:52
SPEAKER_00: The data is out there, but unfortunately, the people in the United States are not being made aware of the data.
8:58
SPEAKER_00: Uh schools, medical schools, day-to-day talk should be about the Mediterranean diet because it actually is a preventative diet.
9:07
SPEAKER_00: So that's one thing, certainly.
9:09
SPEAKER_00: Other things, you know, looking at proper treatment of uh of uh prediabetes, which has become very, very prevalent because of the obesity epidemic.
9:19
SPEAKER_00: And of course, eliminating obvious habits like smoking.
9:22
SPEAKER_00: Fortunately, smoking seems to be uh reducing rather substantially in the United States.
9:27
SPEAKER_00: But, you know, smoke from marijuana has actually there's been some data now to support that the smoke from that's maybe not so good.
9:35
SPEAKER_00: So there are, you know, habits that need to be uh dealt with.
9:39
SPEAKER_00: Again, and the the time to deal with them is early on in life.
9:43
SPEAKER_00: Exercise, proper sleep is very, very important.
9:46
SPEAKER_00: It's it's being found out that proper sleep is even more important than we thought many several years ago, that people really do need to have an average of seven hours of sleep a night, and that's uh an important element.
9:58
SPEAKER_00: Environmental stresses, you know, we've talked about them with oxidative stress.
10:02
SPEAKER_00: I mean, who knows out there with all the electromagnetic radiation we have out there, uh, you know, we probably ought to we ought to probably try to shield ourselves a little bit more from that and avoid obvious toxins out there in the environment.
10:15
SPEAKER_00: You know, the processed food items that uh we're trying to all to hopefully clean that up over time to try to improve our nutrition, not only by content of our nutrition, but in the kind of foods we eat.
10:27
SPEAKER_00: And those those are huge issues, obviously, uh, that are are difficult to deal with as an individual sometimes because society's not dealing with them and the availability of a way to help is not always there.
10:38
SPEAKER_00: You know, it's hard to it's hard to help yourself sometimes.
10:41
Jami: I hope that you guys walked away listening to that piece right there on how many of the things that he identified that are controllables, things that we have in our own power to move our body to fuel our body.
10:54
Jami: When we start talking about food, that could be an entire new conversation about nutrition.
10:58
Jami: But when you look at food, you should have a good relationship with food using it as input.
11:03
Jami: I always say it food is your input that's going to fuel your body.
11:06
Jami: So if we fuel it with poor nutrition, expect a poor outcome, right?
11:10
Jami: And we know that eating is our body's natural rest repair cycle.
11:14
Jami: It's so important, but those are controllable things and moving your body.
11:17
Jami: So I love that you brought that up.
11:19
Jami: But I'm excited to dive a little bit deeper into the biology of what's happening in our body.
11:23
Jami: So you've said this word a couple of times too.
11:25
Jami: And let's explain this for people the word oxidative stress.
11:29
Jami: What's actually happening in our body with oxidative stress and what causes it?
11:34
SPEAKER_00: Oxidative stress is it's interesting, you know.
11:36
SPEAKER_00: It uh by in 1956, Dr.
11:38
SPEAKER_00: Harmon uh presented the thesis or the hypothesis that uh oxidative stress is a major cause of aging.
11:46
SPEAKER_00: And it there's been, as we pointed out in I think many of our light vantage uh talks, that there are over 400,000 studies in uh PubMed about oxidative stress and what an important subject it really is.
12:01
SPEAKER_00: So, what's oxidative stress?
12:03
SPEAKER_00: It's a it's a combination of two major things: environmental stresses, which we have some control over, but certainly environmental stresses, some we've talked about, cigarette smoking, uh, toxins, um, possible EMF, all sorts of things that happen in our environment.
12:19
SPEAKER_00: But unfortunately, it's also in our own cells.
12:23
SPEAKER_00: As our cells produce energy in the mitochondria, it produces it through what's called the electron transport chain inside the mitochondria.
12:32
SPEAKER_00: And when that happens, a natural uh consequence of that is there are there is leakage of some of the electrons in out of the electron transport chain that get into the cell.
12:44
SPEAKER_00: And when that happens, the electrons bind to anything and produce what are called free radicals.
12:50
SPEAKER_00: And free radicals are extremely damaging.
12:53
SPEAKER_00: They will react, they're very reactive, they'll react with anything.
12:56
SPEAKER_00: They react with your DNA, with your protein, with your cell membranes, and damage them all.
13:02
SPEAKER_00: And so a natural consequence of producing energy in a mitochondria produces these free radicals.
13:10
SPEAKER_00: So there's two places basically where oxidative stress happens.
13:13
SPEAKER_00: One's endogenous from our own energy production, the other is external from environmental factors, like we've talked about.
13:21
SPEAKER_00: The interesting that the defense against oxidative stress, therefore, is very, very important and actually goes back to the most primitive multicellular animals.
13:30
SPEAKER_00: You can find oxidative stress defenses even in worms and small multi multicellular animals.
13:38
SPEAKER_00: So it's something that has been dealt with evolutionarily ever since energy production through mitochondria has been present.
13:46
SPEAKER_00: So it's uh something that we've all dealt with.
13:49
SPEAKER_00: But the interesting part about that is that we had to evolve a defense system.
13:54
SPEAKER_00: And that defense system is something that we can activate.
13:57
SPEAKER_00: So leading into the fact that we have, as a company, activators of the oxidative defense system, which is called the NRF-2 system.
14:07
SPEAKER_00: The NRF-2 system is in all of us and can be activated.
14:12
SPEAKER_00: And the NRF-2 can, when it's activated, can go to the nucleus of the cell and bind to the what's called the antioxidant response element or the ARE, which is about 202 genes that will allow the causes the production of antioxidant enzymes, one of which our founder discovered during his PhD thesis, uh superoxide dismutase, which is probably one of the most important discoveries in this antioxidant business and scientific research that's ever been made.
14:46
SPEAKER_00: In fact, they say that measuring the superoxide dismutase is done in McCord units after Dr.
14:52
SPEAKER_00: McCord, who is our founder and who's the one who discovered it.
14:56
SPEAKER_00: So our founder was very, very active throughout his whole life in antioxidant research and therapies.
15:04
Jami: I love that you're leading into all of this because when we when we simplify that conversation, you guys, oxidative stress is at the very center.
15:11
Jami: It's at the very center of what's happening inside of our body, why we age, and and if it goes untreated, right?
15:17
Jami: If it if we don't, if we don't keep up with the what's happening inside of our body, it can create disease.
15:22
Jami: And that's what we want to avoid, right?
15:24
Jami: That's exactly what we want to avoid.
15:25
Jami: But when we know that oxidative stress, when you're saying there's 400,000 studies on PubMed, which is the National Library of Medicine, that's probably lighting a light bulb that says that's something to pay attention to.
15:37
Jami: This is an important conversation.
15:39
Jami: So how do we lower it?
15:40
Jami: I when I have heard Dr.
15:42
Jami: Brett Brimhall, very smart man that we have had on this conversation a lot on Wellness Wednesday, the way that he painted it when we talked about oxidative stress was when you have a high amount of bills, everybody has bills that come in every month, right?
15:57
Jami: But when you don't have enough money to pay the bills, we have debt.
16:02
Jami: And essentially that's what's happening in our body.
16:04
Jami: Our body's going into debt.
16:06
Jami: So we want to help rev up the manufacturing of these important enzymes that Dr.
16:11
Jami: Doug's gonna talk a little bit more about so that we can cover the bills and our body can live in balance.
16:16
Jami: That's why we want to have those conversations so you understand honestly the biology that's happening in you right now.
16:23
Jami: And when we're talking about NRF2, this incredible pathway in 2016, Washington State University said this the discovery of the NRF2 is the most preventative approach to health and the biggest breakthrough in health.
16:39
Jami: And we have something that can turn on that pathway.
16:41
Jami: That's profound.
16:42
Jami: So I would love for you, Dr.
16:43
Jami: Doug, to take this away and really what is activation?
16:46
Jami: I know that's a core conversation that we have on these wellness Wednesdays, but help people understand the power of their own innate biology.
16:54
SPEAKER_00: Right.
16:55
SPEAKER_00: Well, you know, we've we talk about this, I think, uh a lot in Light Danish, but an example of this would be if you're using an antioxidant such as vitamin C, one molecule of vitamin C is an antioxidant, but it only neutralizes one molecular one free radical.
17:13
SPEAKER_00: You're producing millions of free radicals a second.
17:17
SPEAKER_00: And the enzyme superoxide dismutase is able to deal with a million free radicals per second.
17:24
SPEAKER_00: So, unlike taking external antioxidants by activating your own body's antioxidant system and defense system, you're having a hugely more efficient way to deal with the oxidative stress and free radicals.
17:37
SPEAKER_00: You know, the difference between using a garden hose on a fire and a real fire hose on a fire, because that's really what it is.
17:46
SPEAKER_00: It's uh oxidation is uh really a fire.
17:48
SPEAKER_00: And uh one of the things that we say and that we show pictures of it is it's oxidation, that's a fancy word for rusting.
17:55
SPEAKER_00: So we're rusting from the inside out, and we need to remove the rust or prevent more rust at any rate from occurring.
18:03
Jami: Exactly.
18:04
Jami: Nobody wants a rusty machine, so we don't want our body to feel and look that way.
18:07
Jami: So I I would love for you, especially on this conversation of heart health, how does oxidative stress, how does that show up when it comes to the condition of the heart?
18:16
Jami: What would what would it influence?
18:18
SPEAKER_00: Well, the biggest thing is coronary arter disease.
18:20
SPEAKER_00: There's, you know, you can divide heart disease up into many things.
18:24
SPEAKER_00: The one that's the most common problem is coronary arter disease, which leads to heart attacks.
18:29
SPEAKER_00: And it's similar to the mechanism which leads to strokes.
18:32
SPEAKER_00: And this is the reason why early uh prevention is so important.
18:36
SPEAKER_00: So the it's I'm gonna throw a little science in here now.
18:40
SPEAKER_00: Uh so you know, hold on to your seats.
18:43
SPEAKER_00: So coronary or any artery or coronary arteries especially have a lining inside of them.
18:49
SPEAKER_00: That lining is part of the three layers of an artery.
18:52
SPEAKER_00: Artery, remember, delivers blood to the tissue.
18:55
SPEAKER_00: That inner layer of the artery is called the endothelium.
18:59
SPEAKER_00: The endothelium is incredibly important.
19:01
SPEAKER_00: It's a lot more than just a little lining of your blood vessel.
19:04
SPEAKER_00: It controls vasodilation of the blood vessel or the tone of the blood vessel, controls whether the blood vessel creates clots or not, it controls environment hormonal environments in the wall of the blood vessel, and it also prevents inflammation.
19:21
SPEAKER_00: So when you get endothelial dysfunction, it's called, that's the earliest thing in coronary artery disease.
19:28
SPEAKER_00: And that occurs from high blood pressure, it occurs from smoking, it occurs from toxins, it occurs from all sorts of things.
19:34
SPEAKER_00: And that early endothelial dysfunction allows for oxidative stress to begin to occur in the blood vessel wall, the cells of the blood vessel wall.
19:46
SPEAKER_00: That leads to inflammation of the blood vessel wall.
19:49
SPEAKER_00: They're connected.
19:51
SPEAKER_00: Elevated oxidative stress is connected with inflammation.
19:55
SPEAKER_00: And when that happens, that's the very first spot where uh atherosclerosis or hardening of the arteries happens, where the disease begins.
20:04
SPEAKER_00: What happens is now that the blood vessel wall is injured, LDL or low density lipoprotein or lousy cholesterol, if you will, can make its way into the wall of the blood vessel.
20:16
SPEAKER_00: And when it goes into the wall of the blood vessel, it gets trapped and it gets, guess what, oxidized.
20:23
SPEAKER_00: And when it gets oxidized, it gets rusted, it gets trapped, and that causes an immune reaction, which leads to salvaging molecules called macrophages, to go into the blood vessel wall and try to get rid of the LDL cholesterol.
20:40
SPEAKER_00: It can't because it's rusted.
20:42
SPEAKER_00: So what happens is the macrophages turn into what's called foam cells, and foam cells are the original injury that causes the plaque of atherosclerosis.
20:52
SPEAKER_00: And then over years, that uh macrophage plaque grows and turns into an obstructive plaque in the artery.
21:01
SPEAKER_00: And if further inflammation happens, the plaque breaks down and that causes blood clots in the artery and a heart attack.
21:10
SPEAKER_00: So oxidative stress is really important not only at the beginning of the disease when endothelial dysfunction is happening, but it's also incredibly important at the latter part of the disease when you want the plaque to be stable and not inflamed.
21:26
SPEAKER_00: And this is where antioxidants can be of extreme value, especially again at the beginning of the disease.
21:33
SPEAKER_00: And that's where I think materials like uh protandum and NRF2 activators can be of incredible power.
21:42
SPEAKER_00: We know from, we know actually from Dr.
21:44
SPEAKER_00: McCord's research that if you do cultured endothelial cells, this is a wonderful study, he cultured endothelial cells and showed that when they're treated with protandem, they and then you treat them with hydrogen peroxide.
22:00
SPEAKER_00: Which is an incredible oxidizer, that there was a 36% reduction in the death of the cultured endothelial cells when they were treated pro tandem.
22:10
SPEAKER_00: That's an amazing result.
22:12
SPEAKER_00: It shows that it NRF2 activation protects our endothelium in a cultured situation.
22:18
SPEAKER_00: Now, that doesn't always mean we can extend that to human blood vessel, but it certainly makes sense that it extends itself to human to human blood cells.
22:27
SPEAKER_00: He also did the same thing with cultured myocytes, which are his fancy term for heart cells, also showed that treat pretreating with protandin prevented injury when it was treated with hydrogen peroxide, a fairly violent oxidizer, significant uh protection against heart cells.
22:45
SPEAKER_00: So, you know, and again, I hope I didn't throw too much science in there, but it basically the pro NRF2 activation prevents both the lining of the blood vessel and also the heart cells themselves, at least in culture.
22:58
SPEAKER_00: And we want to extend that to thinking that that might be applicable to uh the whole human being and the whole coronary artery.
23:07
Jami: Looking at the big picture, and I I hope that as you guys are listening to this, again, this is the showcase.
23:11
Jami: So we're diving a little bit deeper into the science, and I love that because now we're gonna dive into the products that help support what he's explaining.
23:17
Jami: But I hope that what you're listening to is at the very center, at the very early stages, the very beginning, oxidative stress is a root player.
23:27
Jami: So the simple conversation to have is would a body be benefited from lowering oxidative stress?
23:34
Jami: What's the simple answer?
23:36
SPEAKER_00: The simple answer is absolutely yes.
23:39
SPEAKER_00: And there's a kind of a, you know, oxidative stress obviously is related to pretty much all diseases, but I think everyone's aware that inflammation, chronic inflammation, is related to all diseases as well.
23:51
SPEAKER_00: And NRF2 activation is in is completely connected to what's called NR capabeta, which is another gene activation system that activates and causes the production of inflammatory cytokines.
24:07
SPEAKER_00: Those are the most dangerous things in our body.
24:09
SPEAKER_00: Interleukin 6, interleukin-4, and a number of pro-inflammatory things that are involved in severe body inflammation.
24:17
SPEAKER_00: If you activate NRF2, that goes down.
24:24
SPEAKER_00: It reverses inflammation.
24:26
SPEAKER_00: So when you activate NRF2, there's a direct relationship to deactivating the inflammatory genes.
24:33
SPEAKER_00: And that is critical for pretty much all diseases.
24:37
SPEAKER_00: Certainly heart disease, my own disease, if you will, but but everything else as well.
24:42
SPEAKER_00: Inflammatory diseases, arthritis, neurologic diseases.
24:47
SPEAKER_00: I think it's the root of many, many things.
24:50
Jami: I've started learning about this for the well, 10 years ago.
24:53
Jami: So it's been 10 years of diving into this and really having a better understanding of all that oxidative stress is connected to, which is why I'm passionate about having this conversation, because there are tools at hand that we can utilize to optimize our health.
25:06
Jami: And that's why you guys are here tonight listening to this.
25:08
Jami: So when we're starting to introduce, when we do these Wellness Wednesday showcases, we want to highlight a few products that would really support the conversation that we're having tonight.
25:16
Jami: And tonight specifically, we want to highlight our flagship product, Proteanum NRF2, our sister product Proteanum NRF1, and our Omega, which is Incredible Heart Health Stack.
25:26
Jami: So those are the three that we're gonna dive into.
25:29
Jami: And we'll cover it a little quicker.
25:31
Jami: But here's what I want Dr.
25:32
Jami: Doug to explain to us.
25:34
Jami: We already talked about this pathway NRF2.
25:36
Jami: Can you talk specific to the input that Proteanum NRF2 actually activates sort of the ingredients and how the mechanism and how they actually work?
25:45
Jami: Because we're not supplementing the body with antioxidants, we're doing something very, very different and innovative.
25:50
Jami: So can you explain?
25:51
SPEAKER_00: Yeah, I mean again, I'm gonna throw a little science out there.
25:53
SPEAKER_00: I mean uh it's it's not uh it's not necessarily easy.
25:57
SPEAKER_00: So in the in our cell cytoplasm outside the nucleus, there is a uh combination of a protein system called keep one, which is bound to NRF2.
26:11
SPEAKER_00: Keep one causes NRF2 to be metabolized, it's always chewing it up.
26:16
SPEAKER_00: So when you get electrophilic activators which bind to keep one, it prevents the metabolism of NRF2.
26:25
SPEAKER_00: There are five binding sites on keep one, each one of which becomes occupied by the components of protandem.
26:32
SPEAKER_00: So there's uh it's specific, five different specific things that the five phytochemicals in protandem deactivate.
26:42
SPEAKER_00: It allows keep one to prevent NRF2 from being destroyed, allowing NRF2 to migrate into the nucleus and activate the genetic sequence called ARE to produce the enzymes that we're talking about that are antioxidants.
26:59
SPEAKER_00: And amazingly enough, and Dr.
27:01
SPEAKER_00: McCord, I think, discovered this, that the five different uh five different phytochemicals from the uh turmeric, green tea, bacopa, milk thistle, and ashkawanda all bind five different sites on on keep one.
27:16
SPEAKER_00: So it's it's synergistic as opposed to just additive.
27:20
SPEAKER_00: And it really prevents keep one from metabolizing NRF2.
27:25
SPEAKER_00: So NRF2 becomes free to go into the nucleus and bind the genes that activate uh the antioxidant system.
27:32
SPEAKER_00: So it's a really beautiful system.
27:34
SPEAKER_00: And by the way, what's that?
27:37
Jami: It's a very complex system.
27:39
SPEAKER_00: It's a very complex system, and I could go in, I could go into what each one of them do on keep one because it's defined, but that's a little too complex for tonight's talk.
27:48
SPEAKER_00: So, but the the bottom, the take-home lesson is that uh keep one is uh bound bind it bound by all five of the components of protandum and prevents the metabolism of NRF2, allowing it to be free so it goes into the nucleus and does its job by activating the antioxidant system.
28:08
Jami: Think of it like flipping on that switch.
28:10
Jami: It's that messenger that gets inside the cell that turns that dial up and says, go make all these antioxidant enzymes that go do masterful work inside the body.
28:18
Jami: So we actually have validation to prove that.
28:21
Jami: What's what's the statistic on what protein does in reducing oxidative stress?
28:28
SPEAKER_00: If you're talking about each individual phytochemical, it's 18 times more powerful than each of the phytochemicals individually.
28:36
SPEAKER_00: So yeah, it's very, very powerful.
28:39
Jami: Yeah, which reduces oxidative stress 40% in 30 days.
28:42
SPEAKER_00: 40% in 30 days, 70% in four months.
28:45
SPEAKER_00: Yeah, as measured by T-bar, which is one of the measures of oxidative stress.
28:50
SPEAKER_00: There's other ones that are available.
28:52
SPEAKER_00: Unfortunately, you know, a lot of our clients when we put them on protonum, they say, well, how can I find out whether it's working or not?
28:58
SPEAKER_00: It's a little hard because we don't clinically have T-bars to measure.
29:02
SPEAKER_00: We can measure C reactive protein, uh, lipoprotein phospholipase A2, and also oxidized LDL.
29:09
SPEAKER_00: We can measure that oxidized LDL.
29:11
SPEAKER_00: And you can see a reduction or improvement in oxidized LDL.
29:14
SPEAKER_00: It's amazing how many people have elevated oxidized LDLs, which we're talking about as being the principle behind atherosclerosis.
29:23
Jami: I appreciate that you threw that out there because I know that was a question in the chat.
29:26
Jami: How could people measure that?
29:27
Jami: So the CRP value on your lab work, that's one of the ways that you could measure an inflammatory marker inside of your body.
29:33
Jami: Something to track if that's something you're paying attention to.
29:36
Jami: So, you guys, I think it's hands down obvious why we are so excited that we have a product like this to offer to the world.
29:44
Jami: Protaminor F2 is foundational when it comes to protecting cellular health, and the cells dictate your overall health.
29:51
Jami: And you can hear in this conversation of all the information Dr.
29:54
Jami: Doug is giving us that oxidative stress is the very center of all of it.
29:58
Jami: So our bodies are powerful, they are beautifully created, and they have the ability to turn on our own biology that protect it.
30:06
Jami: So why would we not have NRF2 inside of our body?
30:08
SPEAKER_00: It's such a you know, and we make we make the judgment.
30:12
SPEAKER_00: I think, you know, a lot of people ask me, well, you know, has it had a you know clinical trial or this or that or another thing?
30:18
SPEAKER_00: One of the ways we make a decision as a physician as to whether to treat somebody with something is we call the risk-benefit ratio.
30:26
SPEAKER_00: You know, what's the risk of protandin?
30:29
SPEAKER_00: Near zero.
30:30
SPEAKER_00: What's the benefit?
30:32
SPEAKER_00: Potentially fantastic.
30:34
SPEAKER_00: So that that ratio is so far in favor of treatment that it's not even funny.
30:41
SPEAKER_00: You know, you look at drugs that we use on a daily basis, that risk-benefit ratio isn't always so it's a little more balanced sometimes.
30:49
SPEAKER_00: The risk is seriously there compared to the potential benefit.
30:53
SPEAKER_00: But with this, and again, in terms of heart disease, the earlier on the better.
30:57
SPEAKER_00: People, I think people should be taking that in their 20s, way before this atherosclerosis gets going.
31:03
SPEAKER_00: And this brings us to the even more powerful, I think you talked about it there, Jamie, a little bit, and that's the trisynergizer.
31:10
SPEAKER_00: This is particularly what I take because I want to take our flagship product and even make it more powerful.
31:17
SPEAKER_00: And the way to do that is to use the trisynergy.
31:20
SPEAKER_00: So, and that is looking at other activation pathways, particularly NRF1.
31:25
SPEAKER_00: This one's more complicated than NRF2, so I'm not going to go into the actual chemistry of it, but basically, NRF1 causes mitochondria to divide and cause more mitochondria and cause more efficient mitochondria, both things.
31:42
SPEAKER_00: A heart cell has about 5,000 mitochondria in it, and you can increase those mitochondria significantly by the use of NRF1.
31:50
SPEAKER_00: Brain cells have a million, neurons can have a million mitochondria.
31:55
SPEAKER_00: And if you increase the mitochondria in a neuron, you can imagine that it's going to function better.
32:00
SPEAKER_00: The problem, of course, remember going back to the reason for oxidative stress, the one of the problems of creating more NRF, more mitochondria, is guess what?
32:11
SPEAKER_00: You're producing more oxidative stress.
32:13
SPEAKER_00: So when you activate mitochondria, you've got to have the NRF2 there to prevent any increased oxidative stress you're inadvertently creating.
32:24
SPEAKER_00: You know, a lot of things that we do that are beneficial, like extreme exercise, increases oxidative stress.
32:30
SPEAKER_00: So that's one of the places where NRF2 is extremely valuable, is to create, and same thing here.
32:36
SPEAKER_00: If we increase the mitochondria, we're going to increase the uh oxidative stress.
32:41
SPEAKER_00: So you have to have the NRF2 there to deactivate that increased oxidative stress.
32:45
SPEAKER_00: So they work really well together.
32:47
SPEAKER_00: Now, if you add actually NAD plus, which is the other element of trisynergy, which is to provide more energy to the more substrate, more fuel to the mitochondria to even produce more energy, that you're actually creating a system that is very active to produce energy in a very efficient way, but in a way that's protected.
33:08
SPEAKER_00: And so it can help dramatically increase the function of things like heart cells.
33:13
SPEAKER_00: And in, you know, and that of course is incredible.
33:16
SPEAKER_00: And that's the the thing, the the fact behind the idea that we feel that the trisynergy can help with many things.
33:26
SPEAKER_00: Now we can't make health claims, as you know, but as we look at the basic biology behind what's happening, it's got to have benefits and and uh have influence on other diseases like neurodegenerative diseases, cardiovascular diseases, uh, et cetera, et cetera.
33:45
SPEAKER_00: So really, really important the trisynergy.
33:49
Jami: I love those products.
33:50
Jami: I've been taking all of them ever since they came out.
33:53
Jami: So when you're looking at just as a recap, for tanuminer FT turns on antioxidants, that reduces oxidative stress.
33:59
Jami: It's at the very center of aging, very center of what we know creates dysfunction in the body.
34:04
Jami: Protanaminer F triggers a new pathway that turns on mitochondria.
34:08
Jami: And when you're talking about the organs that he just mentioned, like your heart and your brain, highly metabolic organs, they need that fuel.
34:16
Jami: So what happens when it doesn't have the fuel provided to it?
34:20
Jami: Dysfunction begins.
34:21
Jami: And it dysfunction happens too long, disease sets in.
34:24
Jami: So those two together are the ones who punch in protecting cellular health, and then you get the amplification of adding NAD.
34:30
Jami: If you guys have been on the social media platform at all or listened to any health podcast or been on the news of a health segment, NAD is everywhere.
34:41
Jami: But what you need to understand is your body has the potential to create more of it.
34:48
Jami: You just need the right inputs to get that performance.
34:51
Jami: And that's exactly what he's explaining these three products to.
34:54
Jami: So one of my favorite stacks that we have, and I just want you to speak real quickly to what happens when you layer.
35:00
Jami: Like, why would you lair because of the synergy and the amplification?
35:04
Jami: What it's just an absolute powerhouse when you stack one with the other.
35:08
SPEAKER_00: Right.
35:09
SPEAKER_00: You know, and the funny thing is, of course, people spend hundreds of dollars on intravenous NAD infusions, and it probably does nothing.
35:16
SPEAKER_00: And, you know, to track that into an intracellular or an intramitochondrial increase in NAD is not really been done, but people pay for that.
35:27
SPEAKER_00: And it's uh and again, going with the company philosophy, which I just love, and there's a reason that attracts me to this company, is these these trisynergy and NAD is an activator of these things.
35:40
SPEAKER_00: So more things are being produced naturally, as opposed to assuming that if you give it intravenously or you take it orally, that it's somehow going to get inside the cell and it's somehow going to affect the mitochondria in a positive way.
35:54
SPEAKER_00: We know that if you activate your own system, there's no question that it will improve the function of uh the system.
36:02
Jami: It's like the most personalized biological optimization.
36:06
Jami: It's what we have our hands on.
36:08
Jami: Is your body smart and turn it turn it on?
36:10
Jami: I want you to cover one more product because I know this is something that many people just take over the counter and maybe they don't understand that the the power or importance or even the right ones when it comes to omegas.
36:22
Jami: And I know you you're a data guy, you've done a ton of research.
36:25
Jami: Can you just quickly explain to us the importance and the role and which omegas are important?
36:31
SPEAKER_00: Well, if you have a couple hours, I can uh no as you know, uh this is my area of research when I was a professor.
36:39
SPEAKER_00: And uh omega-3 fatty acids are near and dear to my heart.
36:42
SPEAKER_00: I'm the one that, if you ever heard that omega-3 fatty acids reduce triglycerides, that was my paper.
36:48
SPEAKER_00: And uh so it omega-3 fatty acids are incredibly important.
36:53
SPEAKER_00: This comes and is especially important in brain function and neurologic function, and also in anti-inflammation.
37:01
SPEAKER_00: Uh, the most important omega-3 is EPA.
37:05
SPEAKER_00: EPA substitutes in the inflammatory pathways.
37:09
SPEAKER_00: If you guys have ever heard of a COX-2 inhibitor as a pain, an anti-inflammatory compound.
37:14
SPEAKER_00: There used to be two pharmaceuticals.
37:16
SPEAKER_00: There's still one on the market called Celebrex.
37:19
SPEAKER_00: Another one in the old days used to be called Biox, which was taken off the market.
37:23
SPEAKER_00: But EPA acts as a natural COX-2 inhibitor.
37:28
SPEAKER_00: Cox stands for cyclooxygenase.
37:31
SPEAKER_00: So it's a natural and powerful anti-inflammatory agent.
37:34
SPEAKER_00: So it's like you're using the anti-inflammation activated by NRF2, and you're combining it with the anti-inflammatory properties of EPA.
37:46
SPEAKER_00: EPA also in heart disease has been shown in an Italian study, actually, called GC23 to reduce uh stroke and heart attack by 23%.
37:56
SPEAKER_00: So it's extremely, and it does it product presumably through membrane activation.
38:01
SPEAKER_00: So remember that our membranes of our cells are made from fatty acids.
38:06
SPEAKER_00: And the more double bonds in the fatty acid, the more liquid your cell membrane is.
38:12
SPEAKER_00: And the more liquid your cell membrane is, the better it works because you have hormone receptors and all these receptors and things in the cell membrane, and you want those to work very well.
38:22
SPEAKER_00: And if the cell membrane is liquid, they work better.
38:25
SPEAKER_00: And liquidity depends on the number of double bonds in the fatty acid.
38:30
SPEAKER_00: So saturated fats have no double bonds.
38:32
SPEAKER_00: That's why it doesn't work very well.
38:33
SPEAKER_00: That's one of the reasons why saturated fats are not good for you.
38:36
SPEAKER_00: They get in the cell membrane and they make the cell membrane stiff.
38:40
SPEAKER_00: As you start adding double bonds to the fatty acid, the membrane becomes better and better and better.
38:46
SPEAKER_00: Well, the most popular, most common polyunsaturated fatty acid is linoleic acid, which has two double bonds.
38:54
SPEAKER_00: That's the fatty acid that's in olive oil.
38:57
SPEAKER_00: One of the reasons why olive oil is important in Mediterranean diet and whatnot, EPA has five double bonds.
39:06
SPEAKER_00: So the fish oil has the most double bonded fatty acids you can obtain, and the only way you can get it is through uh fish oil.
39:14
SPEAKER_00: There are some plant omega-3s, but those have not been shown to have cardiovascular benefit.
39:19
SPEAKER_00: So they really have to come from fish oil.
39:22
SPEAKER_00: And by the way, it's not really fish oil.
39:24
SPEAKER_00: Omega-3s are produced actually by algae in the northern, in the Arctic oceans.
39:30
SPEAKER_00: Those algae are eaten by krill.
39:33
SPEAKER_00: Krill are eaten by larger animals, and that's where the pet the omega-3s mostly come from.
39:39
SPEAKER_00: So fishes that have we say fish oil, but it's really fishes that are live or migrate into the polar ocean.
39:45
SPEAKER_00: So herring, sardines, salmon, those kinds of things.
39:49
SPEAKER_00: Your cod or your trout that you get out of the lake there doesn't have any omega-3s in the in its, so it isn't just fish oil, it's fish oil from specific fishes.
40:00
Jami: I have always understood omegas and their importance, and I love that you said liquidity.
40:04
Jami: It makes sense.
40:05
Jami: It protects the integrity of the cell membrane.
40:08
Jami: That's why omegas are incredibly important, but they provide so many benefits to your brain, to your heart, but every cell throughout your body.
40:14
Jami: So I know that our conversation tonight is about the heart specifically.
40:17
SPEAKER_00: In our laboratory, in our laboratory, when I was still doing it, by the way, you think maybe this is a slow process.
40:22
SPEAKER_00: We were actually able to demonstrate the presence of omega-3 fatty acids in cell membranes within 20 minutes.
40:28
SPEAKER_00: This is a very, you think uh this is a very rapid turnover thing.
40:32
SPEAKER_00: And it truly benefits our cell membrane.
40:35
SPEAKER_00: So you can imagine, once again, we talk about synergism.
40:38
SPEAKER_00: We're having the synergism of the NRF2 activation.
40:42
SPEAKER_00: We also have the synergism of the omega-3 fatty acids in EPA being a cyclooxygenase inhibitor and being very anti-inflammatory.
40:52
SPEAKER_00: And that goes through a whole system called leucotrienes and thromboxanes and stuff like that, all of which is too complicated to talk about.
40:59
SPEAKER_00: But basically, it's a powerful COX-2 inhibitor, which is powerfully anti-inflammatory.
41:05
SPEAKER_00: So you're doing two things that are synergistic in the body with the with the combination of those two products that is incredibly important and powerful.
41:15
Jami: So layering protein on NRF2 is the foundation.
41:18
Jami: And as you're hearing this conversation, and clearly we could have hours and hours of conversation, you will be back playing on it.
41:25
Jami: But as we layer more and more activation and great, incredible products like our Omega Plus, you're getting a huge array of benefits that's supporting all of your cellular health so that you're not just your heart, but every system that that your body functions from is optimized.
41:44
Jami: And that's really where this power of activation is the exciting conversation that we love to bring to these wellness Wednesdays.
41:50
Jami: So, you guys, I I love that there's so much that we have dove in with the validation of the science behind it.
41:56
Jami: We will have Dr.
41:56
Jami: Doug to dive down even more on another topic, but I want you to walk away with practical strategies.
42:02
Jami: And I know that this has been a question here real quick, and I want to make sure that people walk away with practical things that they know that that what the numbers they're looking for, what the strategy they have coming out of this, what they can do today.
42:14
Jami: So one of the things I want from the mouth of the cardiologist are what are some of the important numbers when it comes to blood pressure, cholesterol, blood sugars, what are some of those numbers that people should be paying attention to if they're tracking their blood work?
42:29
SPEAKER_00: Well, certainly blood pressure, we know from Framingham risk trials that blood pressure normal on average is 120 over 80.
42:36
SPEAKER_00: Less blood pressure has actually been shown to be better up to the point of people not feeling good because their blood pressure is too low.
42:43
SPEAKER_00: So there is a practical element to that.
42:47
SPEAKER_00: Pilots, I do aviation medical exams, and pilots are allowed blood pressure 150 over 85.
42:53
SPEAKER_00: So 120 over 80 is a target, it's an ideal, but it's not necessarily what everyone has to reach.
43:01
SPEAKER_00: In terms of cholesterol, I think it's important to look at not only cholesterol and LDL and the subfragments of cholesterol, but also to look at what's called advanced cardiac markers.
43:12
SPEAKER_00: Very, very important in these days.
43:13
SPEAKER_00: Everyone should know what their LDL cholesterol is.
43:16
SPEAKER_00: The lousy or LDL cholesterol is the important thing.
43:20
SPEAKER_00: The guideline goal is to have the LDL less than 100, but realistically, if you have any atherosclerosis or placking, it needs to be under 70.
43:29
SPEAKER_00: That's when you get regression of plaque.
43:31
SPEAKER_00: So treating cholesterol isn't just treating cholesterol, it's getting plaque to regress, get better.
43:36
SPEAKER_00: We do that every day in our clinic.
43:38
SPEAKER_00: And we follow that with carotid ultrasounds.
43:40
SPEAKER_00: So you can show with a carotid ultrasound that if you have a 30% narrowing in your carotid, you have no symptoms from that, but that's a pretty good sized plaque.
43:48
SPEAKER_00: And we can show with proper reduction of your LDL cholesterol that that plaque gets better.
43:53
SPEAKER_00: So that's what you want, not just lowering the cholesterol.
43:56
SPEAKER_00: A very, very important differentiation.
44:00
SPEAKER_00: Is not a laboratory disease, it's a blood vessel disease.
44:02
SPEAKER_00: So you want to look at blood vessels to really understand what's happening with your body.
44:07
SPEAKER_00: And statistically, your carotid disease has a high statistical association with coronary disease.
44:13
SPEAKER_00: And the carotid is something that you can cheaply and safely look at and inexpensively look at on multiple occasions without the risk.
44:21
SPEAKER_00: So it's really, really important.
44:23
SPEAKER_00: Other advanced cardiac markers, most important being apolipoprotein B, that is the lip, that is a port the protein portion of LDL cholesterol.
44:33
SPEAKER_00: So when you look at APOB, that tells you how large, dense, or the number of LDL particles, and whether those particles have a propensity to work themselves into the blood vessel wall or not.
44:46
SPEAKER_00: So actually, in the modern day, the most important number to look at is your APOB, not LDL cholesterol.
44:52
SPEAKER_00: And that could be obtained through advanced cardiac markers.
44:55
SPEAKER_00: Another really important thing, which we haven't discussed a lot here, the other big theory of aging is what's called advanced glycation in products or age.
45:03
SPEAKER_00: That's based on your glucose.
45:06
SPEAKER_00: So one of the other really important things is your fasting insulin level.
45:10
SPEAKER_00: So most people don't know that or haven't obtained that, but I would say between the most important things that people haven't typically gotten is APOB and fasting insulin levels are critical to judging your cardiovascular risk profile.
45:24
Jami: So I would say if you have not had a blood panel done in years, maybe this is a great point.
45:30
Jami: Maybe this is a great starting point because your blood could tell you a lot of things that are going on inside of your body so that you can be proactive and preventative.
45:37
Jami: One thing that I want you to eat.
45:40
Jami: Sorry.
45:41
Jami: Well, one thing that I would love for you to be able to answer because I've, as you said it, I realize I've had this conversation so many times that people don't truly understand what the numbers mean in blood pressure.
45:51
Jami: And I think if you can explain what's happening in the heart and what those numbers mean, it might click that they understand why that number needs to come down.
46:01
SPEAKER_00: The answer to that is not so simple.
46:09
SPEAKER_00: Yeah, your your heart, it's you think of your heart as a muscle.
46:13
SPEAKER_00: And if you go and lift weights, your arm muscle gets big, right?
46:17
SPEAKER_00: You like that.
46:18
SPEAKER_00: In your heart, if your heart is pumping against a high blood pressure, your heart also enlarges.
46:25
SPEAKER_00: The walls of your heart get thick, and in the heart, that's not good.
46:30
SPEAKER_00: Uh that increases the what's called the diastolic pressure inside the heart, increases the wall tension, increases the risk that your heart is going to be dysfunctional as a result of that.
46:42
SPEAKER_00: So high blood pressure causes the heart to be dysfunctional.
46:45
SPEAKER_00: And if it goes to a large extent, it can cause the heart to fail.
46:49
SPEAKER_00: Because just like lifting a weight, if you're lifting a weight that you is too heavy for you to lift, your heart, your muscle can't do it.
46:56
SPEAKER_00: That's what happens to your heart.
46:58
SPEAKER_00: If your blood pressure is too high, then uh your heart actually ends up failing as a result of it being unable to lift against a high that high blood pressure, which is basically lifting weights for the what for the heart.
47:10
SPEAKER_00: So that's the simple answer to it.
47:12
Jami: Yes, I think it's important for people to understand that bottom number is really where your heart is at rest.
47:17
Jami: And when that number still stays high, there's a lot of pressure on those vessel walls, and there's a lot of pressure in that heart.
47:22
Jami: And a big heart muscle actually creates a weak heart.
47:25
Jami: So I love that you're talking about this.
47:28
Jami: I could pick your brain all night long, and I hope that you come back for more.
47:31
Jami: I mean, basically show Dr.
47:33
Jami: Doug some love in the chat.
47:34
Jami: I know we went a little long, but while I have somebody here like this and we can ask all of these questions, let's get them answered.
47:40
Jami: This has been phenomenal.
47:41
Jami: It's been in-depth, which is what we want, the showcase about our products.
47:46
Jami: What again, just it was proteanum in RF2, Proteanaminer F1, our omega, and even Proteanamin AD.
47:51
Jami: That's why it's called the Tri-Synergizer.
47:53
Jami: It's the three powerhouse activators.
47:55
Jami: Dr.
47:55
Jami: Doug, I want you to get the last word.
47:57
Jami: If someone were to walk away from this call tonight, give them three practical strategies of what they can do that are in their control to move their health forward.
48:06
SPEAKER_00: The biggest thing is to pay attention.
48:09
SPEAKER_00: As uh Jamie said, get some blood work, find out uh where you fit in the risk profiles and do it early.
48:17
SPEAKER_00: And do it often and so you find out what the right thing to do.
48:21
SPEAKER_00: And then in our case, as far as I'm concerned, everybody in the world should be on pro tandem and it should be earlier than later.
48:29
SPEAKER_00: So do it in your 20s, uh, where the prevention actually, where it can actually act the best for prevention.
48:35
SPEAKER_00: And then don't ignore things.
48:38
SPEAKER_00: Make sure that not only did you take action against the things that you've identified, but identify the fact that you've improved them, which can be done and keep a serial look on things so that you can prevent, you can be one of those 86% of people whose heart attacks are prevented.
48:57
Jami: I love this.
48:58
Jami: You have been a wealth of knowledge.
48:59
Jami: Thank you so much for your expertise.
49:01
Jami: I know we will have you back.
49:02
Jami: You guys, your body is incredible.
49:04
Jami: Your body works so hard for you, so it's up to us to work hard for it.
49:08
Jami: Thank you for being here on this wellness Wednesday tonight.
49:11
Jami: We do these every single Wednesday, so come back to learn more, hear it from a different expert and broaden your knowledge when it comes to things that you can do when it comes to your health.
49:20
Jami: Have a blessed week, and we will see you next week.
49:24
Jami: My pleasure.
49:24
SPEAKER_00: Hope to see you back.
49:26
Jami: Thank you so much.