Latest / Hardiness with Dr Paul Taylor / The Hidden Impact of Stress and Environmental Toxins on Your Hormones and Aging

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The Hidden Impact of Stress and Environmental Toxins on Your Hormones and Aging · Hardiness with Dr Paul Taylor

• 0:09
  Speaker 1: Doctor Mike Fortunato. Welcome to the podcast.
• 0:13
  Speaker 2: Oh, thank you, Paul. It's a pleasure. Appreciate the opportunity.
• 0:16
  Speaker 2: All the way from from Vegas. I was actually I
• 0:20
  Speaker 2: was actually telling you his funny story. There's a couple
• 0:23
  Speaker 2: of utes of mine who are over there right now,
• 0:24
  Speaker 2: and we're going from Dallas to Los Angeles. Got to
• 0:28
  Speaker 2: the gate and the lady said, you're not that's the
• 0:31
  Speaker 2: wrong ticket. You're going to La S not La X.
• 0:37
  Speaker 3: Oops. Yeah. Cool, cool laying layover though, cool layover. Yeah.
• 0:44
  Speaker 1: In fact, I was.
• 0:45
  Speaker 4: I was in Vegas twenty jeez.
• 0:49
  Speaker 1: Nicely thirty years ago.
• 0:50
  Speaker 4: Now, I was in Vegas and man, it was a
• 0:53
  Speaker 4: crazy caricature. And then I'm sure it must be just
• 0:55
  Speaker 4: bonkers right now. Oh it's the whole strip.
• 0:59
  Speaker 3: Yeah, it's different. Now it's it's like major big time. Yeah,
• 1:04
  Speaker 3: thirty years ago, it must have been chill. It's it's
• 1:07
  Speaker 3: pretty cool. I enjoy it, actually, you know, it's it's
• 1:09
  Speaker 3: it's there if you need it. And then the rest
• 1:11
  Speaker 3: of the time you live in the suburbs, so it's good.
• 1:13
  Speaker 4: Yeah yeah, and then pretty pretty good weather.
• 1:15
  Speaker 3: Eh. The only time it's bad is the summer, when
• 1:18
  Speaker 3: it's one hundred and twenty degrees. But otherwise you can't complain.
• 1:23
  Speaker 3: The winners are beautiful. No snow, yeah, no, I love
• 1:26
  Speaker 3: it so mate.
• 1:27
  Speaker 4: You are what we would call over here an anisitis,
• 1:32
  Speaker 4: and you call it an aneasityol.
• 1:34
  Speaker 3: It was, yeah, it's it's ridiculous, Yeah, anesthesiologist. You know,
• 1:39
  Speaker 3: it took me forever to spell that when I was
• 1:40
  Speaker 3: when I was starting out.
• 1:43
  Speaker 4: So give on, give on listeners a sense of how
• 1:47
  Speaker 4: long it actually takes for you, from the first day
• 1:51
  Speaker 4: in medical school all the way to hey, you're right
• 1:55
  Speaker 4: on your own.
• 1:56
  Speaker 1: You're a big boy.
• 1:56
  Speaker 3: And I sure you got to go four years of
• 2:01
  Speaker 3: medical school, which the first two years are really just
• 2:04
  Speaker 3: at the books, academic you don't typically you see patients
• 2:08
  Speaker 3: very mildly. They're just doing basic exams, but first two
• 2:11
  Speaker 3: years heavy book stuff. The second or third and fourth
• 2:16
  Speaker 3: year of medical school then you start to do rotations
• 2:18
  Speaker 3: in certain specialties preparing you for your residency. Then you
• 2:26
  Speaker 3: take a board exam and you apply to a specific
• 2:28
  Speaker 3: residency of training that you want to pursue, so whether surgery,
• 2:31
  Speaker 3: general medicine, whatever it is. Then you have those interview
• 2:37
  Speaker 3: processes and then you get into a residency, and depending
• 2:40
  Speaker 3: on the residency you choose, the duration of time is
• 2:42
  Speaker 3: dictated by the boards. So for anesthesia it's four extra years.
• 2:46
  Speaker 3: So you do four years of medical school, four years
• 2:48
  Speaker 3: of anesthesia training residency. Although it's much different now than
• 2:53
  Speaker 3: it used to be. We used to have no limits
• 2:57
  Speaker 3: of time. Although actually no they changed in my last year.
• 3:00
  Speaker 3: Typically there was no no duration of time which they
• 3:01
  Speaker 3: couldn't work you. So you would work, you know, thirty
• 3:04
  Speaker 3: six hours, take a nap, go back. This was not atypical. Uh.
• 3:10
  Speaker 3: And you do that for four years.
• 3:11
  Speaker 2: Uh.
• 3:11
  Speaker 3: And you try to absorb and learn as much as
• 3:13
  Speaker 3: you humanly can possibly learn so that when you go
• 3:16
  Speaker 3: out on your own, you're not scared shitless the first
• 3:19
  Speaker 3: time you enter the oar all by yourself, right, And
• 3:22
  Speaker 3: so it's a process. It's Uh. I've never been in
• 3:27
  Speaker 3: a military, but I think it's very much similar to
• 3:29
  Speaker 3: those those standards.
• 3:32
  Speaker 4: I was justified to say because because I'm ex military,
• 3:36
  Speaker 4: and for me when you're a junior doctor, and because
• 3:41
  Speaker 4: my daughter is thinking of going time that pathway right now.
• 3:44
  Speaker 1: But but I know, I know quite a few doctors.
• 3:46
  Speaker 4: When you're a junior doctor, it's kind of the equivalent
• 3:49
  Speaker 4: of stress and oculation training.
• 3:52
  Speaker 1: But it goes on for years.
• 3:55
  Speaker 3: And you just said, you know, like the military, Then thanks, sir,
• 3:57
  Speaker 3: Can I have another You don't You don't question, and
• 4:00
  Speaker 3: you just do as you're told and you keep your
• 4:02
  Speaker 3: head down and work hard. At least that's what it
• 4:04
  Speaker 3: was when we did it. Times have changed a bit.
• 4:07
  Speaker 1: Man, your specialization. It's quite interesting.
• 4:09
  Speaker 4: I mean, you hear all the time about surgeons operating
• 4:14
  Speaker 4: on the wrong leg or leaving something inside the patients.
• 4:19
  Speaker 4: You don't get many biballs, do you.
• 4:22
  Speaker 3: You typically don't, you know, so this is what it's
• 4:27
  Speaker 3: They equate it. You know. Again, I've never been a pilot,
• 4:29
  Speaker 3: but it's similar to that. Right, The landing and the
• 4:31
  Speaker 3: takeoff are the most important. Then the rest you're kind
• 4:34
  Speaker 3: of just cruising, you know. You hope that the preoperative screening,
• 4:40
  Speaker 3: which has become very good in medicine, you know, will
• 4:44
  Speaker 3: prevent most of the troubles you're going to get into
• 4:47
  Speaker 3: that you can't at least manage, you know, the shocking things.
• 4:51
  Speaker 3: But then again, you know, life is sometimes very random,
• 4:54
  Speaker 3: and people who are not supposed to do poorly will
• 4:57
  Speaker 3: scare the hell out of you and people who you
• 4:59
  Speaker 3: expect that you're going to have a problem sail through
• 5:03
  Speaker 3: life is it's very very interesting what you see in medicine.
• 5:07
  Speaker 4: So man's I mean, it's a highly regarded profession, even
• 5:11
  Speaker 4: within medicine because of the risks and the pressure that
• 5:14
  Speaker 4: you guys around there. So why did you decide to
• 5:18
  Speaker 4: transition out of that which is kind of the pinnacle
• 5:22
  Speaker 4: of the normal medical system and take a different direction?
• 5:26
  Speaker 3: Yeah? You know, so I've been in medicine overall, with
• 5:30
  Speaker 3: training in twenty twenty years, you know, and maybe about
• 5:36
  Speaker 3: twelve years ago, probably sooner, probably fifteen years while I
• 5:40
  Speaker 3: was in a residency, I felt like crap. You know.
• 5:42
  Speaker 3: Of course, I was not a traditional I was not
• 5:44
  Speaker 3: a traditional medical student in the sense that I started later,
• 5:48
  Speaker 3: I bartended, I did a lot of career things before
• 5:50
  Speaker 3: I decided to go back to school. But when I
• 5:53
  Speaker 3: was in training, I was in my early thirties, and
• 5:57
  Speaker 3: I was exhausted all the time. And you know, you're
• 6:00
  Speaker 3: a call, you're you're not sleeping, so you just equated
• 6:02
  Speaker 3: to the lifestyle of medicine. You're stressed. As I got
• 6:06
  Speaker 3: closer to the end of my residency where I'm going
• 6:08
  Speaker 3: to go on my own. I just was like, I
• 6:10
  Speaker 3: just feel awful. You know, I was married. I had
• 6:14
  Speaker 3: no no drive, no motivation. I could get through the
• 6:17
  Speaker 3: day out of pure will. I have strong will, so
• 6:20
  Speaker 3: I knew I had to had to do the job.
• 6:22
  Speaker 3: So I just showed up. But things just felt off.
• 6:26
  Speaker 3: I just did not feel good. And at that time
• 6:29
  Speaker 3: I went to my colleagues. They ran some labs. They
• 6:32
  Speaker 3: told me I was normal, You're You're fine, You're just tired.
• 6:34
  Speaker 3: It's residency. This is life. You know, when you get
• 6:36
  Speaker 3: out it'll be a little bit better. So just shoot
• 6:39
  Speaker 3: for that, you know. So I got out a residency
• 6:41
  Speaker 3: and it continued. It continued for years, and I said,
• 6:46
  Speaker 3: now this isn't this isn't okay. You know, as a doctor,
• 6:48
  Speaker 3: I know, I knew what I used to feel like,
• 6:50
  Speaker 3: and I just feel off. I don't want to have
• 6:52
  Speaker 3: any sexual relationship with my wife. I love her. What's
• 6:54
  Speaker 3: going on here? This is you know. I was I
• 6:56
  Speaker 3: was forcing it once a month just to keep the
• 6:59
  Speaker 3: relationship because I know how important it was. But I
• 7:02
  Speaker 3: had nothing, and so I found someone to see me.
• 7:07
  Speaker 3: At the time, this was now twelve years ago, probably
• 7:11
  Speaker 3: my labs were abysmal, but they were in the normal range, right,
• 7:15
  Speaker 3: and so you.
• 7:16
  Speaker 1: Know, low end, low end of normal, as they say, and.
• 7:20
  Speaker 3: This you know your labs are normal, can be can
• 7:23
  Speaker 3: be one of the most devastating things told to a patient.
• 7:27
  Speaker 3: This is what I've learned in hormones because what's labeled
• 7:31
  Speaker 3: as normal is based on the population average, and what
• 7:36
  Speaker 3: we see in good research is that the population average
• 7:39
  Speaker 3: is actually quite sick hormonally, and so we're gauging everybody
• 7:43
  Speaker 3: to that when in fact, all the research shows we
• 7:46
  Speaker 3: have to typically go outside the rangers of normal to
• 7:50
  Speaker 3: get symptomatic benefit, right, And this is this is good
• 7:52
  Speaker 3: research that shows us. But at the time, and who
• 7:55
  Speaker 3: knew this, right, We didn't. We didn't know this. And
• 7:57
  Speaker 3: as a side note, in medicine, you know, they don't
• 7:59
  Speaker 3: They don't each hormones very well in the sense that
• 8:03
  Speaker 3: they say, hormones are very sophisticated. They can be very troubling.
• 8:08
  Speaker 3: They can cause a lot of disease. Right, We've been
• 8:11
  Speaker 3: taught cause cancers and things like this, men, prostate cancers.
• 8:13
  Speaker 3: What they used to tell us, yeah, strokes, heart attacks,
• 8:16
  Speaker 3: breast cancers, what they used to tell us. These things
• 8:19
  Speaker 3: are not true when you look at the good research now,
• 8:21
  Speaker 3: but this is what we were taught. And medicine is
• 8:23
  Speaker 3: very slow to adapt to old edicts, right, and so
• 8:29
  Speaker 3: this is what we were taught. So you said, just
• 8:31
  Speaker 3: stay away from that stuff. And so for the most part,
• 8:33
  Speaker 3: we do it, and we don't test it. Right, Hormones
• 8:35
  Speaker 3: are not tested. You don't go to your doctor, and
• 8:37
  Speaker 3: they don't test testosterone. They do, maybe now more so
• 8:40
  Speaker 3: than they used to, but think this was not a
• 8:42
  Speaker 3: common occurrence. And when they do test it. We used
• 8:46
  Speaker 3: to have age dependent ranges, right, we'd say, hey, from
• 8:49
  Speaker 3: ten to twenty, your range should be within this. This
• 8:51
  Speaker 3: is normal for that age group, twenty to thirty, thirty
• 8:54
  Speaker 3: to forty. They no longer do that. Everybody's lumped in together.
• 8:58
  Speaker 3: So a twenty year old and eighty or yeah, and
• 9:00
  Speaker 3: so a twenty year old and eighty year old can
• 9:03
  Speaker 3: have the same number and it's considered normal. And so
• 9:06
  Speaker 3: what ends up happening is that I had my labs
• 9:09
  Speaker 3: done and I was barely above the normal. But I
• 9:11
  Speaker 3: think like one or two points. But if you look
• 9:14
  Speaker 3: at the research, that was equated to about an eighty
• 9:17
  Speaker 3: year old from about thirty years ago, right, and I'm
• 9:20
  Speaker 3: in my thirties, right, So this wasn't normal. So I
• 9:23
  Speaker 3: found someone who would treat me, and you know, I
• 9:26
  Speaker 3: went through a gamut of poor treatment, but I was
• 9:30
  Speaker 3: getting effects of at that time just testosterone, and man,
• 9:35
  Speaker 3: I started to feel like myself again and I couldn't
• 9:39
  Speaker 3: believe that this was that this was not being talked about,
• 9:42
  Speaker 3: that this was not being discussed. I dove into this heavily,
• 9:47
  Speaker 3: you know, and at the time there was not much research.
• 9:50
  Speaker 3: At least there was research, but a lot of it
• 9:52
  Speaker 3: you had to go digging for. It wasn't readily available.
• 9:54
  Speaker 3: There's a lot of books and stuff like now there's
• 9:56
  Speaker 3: more about testogrope. And it became a passion of mine
• 10:01
  Speaker 3: and I was doing my anesthesia stuff and I've ran
• 10:04
  Speaker 3: it too a lot of cool people on social media
• 10:07
  Speaker 3: and things that I actually helped educate me at the time,
• 10:10
  Speaker 3: because like I said, modern medicine does not teach this prevenently.
• 10:15
  Speaker 3: And I went and got some formal training. And this
• 10:20
  Speaker 3: is my passion because I realized that it's not just testosterone.
• 10:25
  Speaker 3: People think that, well, this is the big thing, right TRT,
• 10:29
  Speaker 3: but hormonal dysfunction at least in our in our nation
• 10:33
  Speaker 3: is rampant. It is global, and it is not just testosterone.
• 10:40
  Speaker 3: It's women with their progesterone estrogen. It's thyroid disease globally.
• 10:45
  Speaker 3: And what I see what I treat patients, is that
• 10:48
  Speaker 3: when one hormone is dysfunction, they all are it's it's astounding,
• 10:55
  Speaker 3: but we're not treating it because it's in the normal range. Paul,
• 10:58
  Speaker 3: this is what's happening. And so when when the doctors
• 11:00
  Speaker 3: are not taught to look at these hormonal dysfunctions, they
• 11:03
  Speaker 3: just say, hey, the lab's normal, you're good at something else.
• 11:06
  Speaker 3: And so I see a lot of patients that come
• 11:08
  Speaker 3: to me feeling the same symptoms and things that I
• 11:12
  Speaker 3: went through and now and I know like what they're
• 11:14
  Speaker 3: going through, and I know, you know, we're going to
• 11:16
  Speaker 3: get you there. But we have to look globally at everything.
• 11:18
  Speaker 3: It's not just TRT. I think that's one misconception that's
• 11:20
  Speaker 3: out there for sure.
• 11:22
  Speaker 4: Yeah, So I want to dig into this a little
• 11:25
  Speaker 4: bit and talk about the drivers of poor hormonal status,
• 11:32
  Speaker 4: particularly in modern developed nations like where you live and
• 11:36
  Speaker 4: like where I live, but also then what's going on biologically.
• 11:40
  Speaker 1: So I don't know a shitload about hormones. I know
• 11:43
  Speaker 1: a little bit, but not a lot.
• 11:44
  Speaker 4: But what you're describing to me that lifestyle, I mean
• 11:49
  Speaker 4: stress is stress is my bag, right, That's where I operate.
• 11:53
  Speaker 4: So you've had years of poor sleep and high stress.
• 11:58
  Speaker 4: So your body's manufacturing a shitload a cordisole. You're in survival,
• 12:03
  Speaker 4: You're in survival mode, right, So you know that's when
• 12:07
  Speaker 4: you're talking. That's what's going through my head. Is is
• 12:10
  Speaker 4: just because I know what chronic stress does to what
• 12:13
  Speaker 4: that hyper cortisol emia does to the body and the brain.
• 12:17
  Speaker 4: It is just it's just widespread carpet bombing, really and
• 12:22
  Speaker 4: so and so my question is do you think that
• 12:25
  Speaker 4: that is.
• 12:26
  Speaker 1: The main driver in you? And then when you.
• 12:31
  Speaker 4: Throw the average American or the average Australian who also
• 12:35
  Speaker 4: has a shit diet of high ultra processed foods so
• 12:38
  Speaker 4: high energy density, low nutrient density, and then maybe poor
• 12:44
  Speaker 4: sleep as well as.
• 12:45
  Speaker 1: All of the stress.
• 12:47
  Speaker 4: Yeah, like obviously that would probably combined being a very
• 12:52
  Speaker 4: a very stressful, sleep deprived environment for years.
• 12:57
  Speaker 3: This is a yeah, there's it's multi factorial, right, So
• 13:02
  Speaker 3: absolutely cortisol shuts down and suppresses testosterone. This is a
• 13:07
  Speaker 3: known biological reaction to this, right, and so of course
• 13:11
  Speaker 3: there is a huge component of that, right, and lack
• 13:15
  Speaker 3: of sleep. Right, All these things affect your hormonal balance diet. However,
• 13:22
  Speaker 3: what is what I see which and that's one major
• 13:25
  Speaker 3: part of it, and that's there's no doubt about it.
• 13:27
  Speaker 3: Stress is a huge component of hormonal dysfunction.
• 13:30
  Speaker 4: And Mike, sorry, before you go down a deeper track,
• 13:34
  Speaker 4: and does high levels of cortisol not only in effect,
• 13:38
  Speaker 4: does it affect estrogen and progesterone as well in women
• 13:42
  Speaker 4: or is it mainly testosterone.
• 13:45
  Speaker 3: And to some extent yes, but mainly testosterone has a
• 13:49
  Speaker 3: huge component the issue with women. And so this was fascinating.
• 13:55
  Speaker 3: We know that in at least in this country. The
• 13:58
  Speaker 3: Enderkrin Society, right, it's it's world renowned, very reputable society
• 14:02
  Speaker 3: based out of Washington, DC. And they came out in
• 14:05
  Speaker 3: twenty fifteen and said, we have massive endocrine disruption going
• 14:10
  Speaker 3: on in this nation from chemicals that are being used
• 14:15
  Speaker 3: in every aspect of our life. Right to preserve foods longer,
• 14:19
  Speaker 3: to keep you know, the crops from being spoiled or
• 14:22
  Speaker 3: being eaten by pesticides, things we spray on our furniture
• 14:26
  Speaker 3: to keep it flame retardant things in our lotions. It's
• 14:30
  Speaker 3: just endless, right everything.
• 14:31
  Speaker 4: They read the shit, the shit that we put on
• 14:33
  Speaker 4: our skin, which is your biggest organ, right, and it's absorbed,
• 14:37
  Speaker 4: and it's absorbed massively.
• 14:38
  Speaker 3: And we're pasting this stuff on and you read the
• 14:40
  Speaker 3: back of the container and you can't pronounce any of
• 14:43
  Speaker 3: the words, right, And if you can't pronounce it, it's
• 14:46
  Speaker 3: probably not doing you a good service. And they found
• 14:49
  Speaker 3: that most of it is very specifically affecting your endocrine system,
• 14:54
  Speaker 3: and they came out and laid a gamut of things
• 14:56
  Speaker 3: it's doing thyroid, progesterone, estrogen, osterone right across the world.
• 15:01
  Speaker 3: This was a twenty fifteen they said this, And think
• 15:03
  Speaker 3: about how much more talks we are now. Yeah, And
• 15:06
  Speaker 3: those those endocrine chemicals, they mimic hormones, they block production
• 15:12
  Speaker 3: of it, they block downstream effects of it, and so
• 15:16
  Speaker 3: we have that as a huge component of what's going on,
• 15:19
  Speaker 3: because that is actually they've shown is some of it
• 15:22
  Speaker 3: is getting into our DNA and we're passing it on
• 15:25
  Speaker 3: to our children. And I see this. I see this
• 15:29
  Speaker 3: anecdotally with me and other colleagues where we take labs
• 15:32
  Speaker 3: of an eighty year old, because I have patients who
• 15:35
  Speaker 3: are I've seen patients as young as twenty and looked
• 15:38
  Speaker 3: at their labs until eighty men and women, and what
• 15:41
  Speaker 3: we see is a very step word fashion decrease. Whereas
• 15:44
  Speaker 3: an eighty year old will have more testosterone for men
• 15:48
  Speaker 3: than a sixty year old, and a sixty will have
• 15:51
  Speaker 3: better than a forty, and a forty is better than
• 15:53
  Speaker 3: a twenty year old. And it's coming down consistently.
• 15:57
  Speaker 4: And is that because the younger people are more in
• 16:01
  Speaker 4: mars than not lifestyle and when it gets the younger,
• 16:04
  Speaker 4: it has a bigger effect than people who've been around longer.
• 16:08
  Speaker 3: There's a definite component to where the environment's more toxic.
• 16:11
  Speaker 3: So they're getting it right from the beginning, right, whereas
• 16:14
  Speaker 3: an eighty year old may only had started in their
• 16:16
  Speaker 3: thirties or forties, where a twenty year old's getting it
• 16:19
  Speaker 3: right from the start. But there is the component of
• 16:22
  Speaker 3: are we passing on some of this dysfunction to our
• 16:27
  Speaker 3: children in the sense of an inheritance? Right? There is
• 16:31
  Speaker 3: a component where we used to never think if you
• 16:34
  Speaker 3: were obese during pregnancy that you had an increased risk
• 16:38
  Speaker 3: of your children being obese. This is an expression of
• 16:42
  Speaker 3: your genes. This was maybe habits. They're showing that if
• 16:46
  Speaker 3: you're a smugger during your pregnancy, your children have a
• 16:48
  Speaker 3: high risk of smoking. If your obese during pregnancy, your
• 16:52
  Speaker 3: children have so situationally, where you are at that conception,
• 16:56
  Speaker 3: your gene expression affects what your children's genes are. We
• 16:59
  Speaker 3: never thought that was possible, and that changes the whole
• 17:02
  Speaker 3: game because now we're passing on these things that we
• 17:05
  Speaker 3: didn't We thought we passed one hundred percent perfect genes
• 17:08
  Speaker 3: or we're not. We're not doing at all.
• 17:11
  Speaker 4: And so, Mike, what you're talking about here is epigenetic
• 17:13
  Speaker 4: and hypogenetics, right so, and just just for the listeners,
• 17:18
  Speaker 4: you know, think of genes like the light switches. I sorry,
• 17:21
  Speaker 4: the lights and epigenetics are the switches that determine how
• 17:25
  Speaker 4: much and high little and when that gene is activated.
• 17:28
  Speaker 4: And to your point, and I think a lot of
• 17:31
  Speaker 4: people don't realize this.
• 17:32
  Speaker 5: Even the the the physical fitness of the god at
• 17:39
  Speaker 5: the time of conception as a bigger at the time
• 17:42
  Speaker 5: of conception, right so, the dad has an impact, the
• 17:45
  Speaker 5: mom has a greater impact.
• 17:47
  Speaker 4: And then you know, if the mom is having a
• 17:49
  Speaker 4: shit diet during pregnance. We actually, no, I know that
• 17:53
  Speaker 4: that if the mom has a crappy diet during pregnancy
• 17:57
  Speaker 4: and if the dad is not in great state as well,
• 18:01
  Speaker 4: there's big increases in mental health conditions, even autism. Right,
• 18:07
  Speaker 4: We're now seeing the maternal diet is having an impact
• 18:10
  Speaker 4: on that ADHD depression exactly as well as all of
• 18:13
  Speaker 4: the physical stuff.
• 18:14
  Speaker 3: Right. We didn't think this, right, We thought, well, you
• 18:17
  Speaker 3: get good genes no matter what mom and dad are doing. Well,
• 18:19
  Speaker 3: you know, you know, we thought hardcore drugs and alcohol
• 18:22
  Speaker 3: were the worst thing you had to worry about. But no, Yeah,
• 18:25
  Speaker 3: you could have one child where you guys were obese
• 18:27
  Speaker 3: and then you guys said, hey, we're gonna get We're
• 18:29
  Speaker 3: gonna get fit, and then you your your second child
• 18:31
  Speaker 3: is while you're fit and eating well, and they have
• 18:33
  Speaker 3: a totally different potential right that. It's crazy now, it
• 18:38
  Speaker 3: is those splits.
• 18:41
  Speaker 4: So so what then, what then is happening biologically inside
• 18:47
  Speaker 4: people who have got a combination Maybe there's a combination
• 18:52
  Speaker 4: of stress, per sleep and a biochemical shit show going
• 18:56
  Speaker 4: on inside, Like, just just give us a sense of
• 19:01
  Speaker 4: how that affects us biologically.
• 19:04
  Speaker 3: Sure, so you know you don't you have your cours
• 19:07
  Speaker 3: all spikes if this is what's going on exclusively, and
• 19:10
  Speaker 3: think about it. You don't have to have you don't
• 19:11
  Speaker 3: have to be an anesthesiologist to have stress. Right, Stress
• 19:14
  Speaker 3: is I'm a very personal mental thing. Right. Uh. You
• 19:18
  Speaker 3: might not be able to pay your bills this month.
• 19:20
  Speaker 3: That's extreme stress, right, that's extreme stress. You may have
• 19:23
  Speaker 3: a sick child or a sick parent you're taking care of, right.
• 19:26
  Speaker 3: It may be trivial to you to me, right, their
• 19:30
  Speaker 3: stress may be like, hey, my girlfriend's not on the
• 19:33
  Speaker 3: same page as me. We don't know situationally how much
• 19:36
  Speaker 3: that impacts that individual for us, and maybe hey that's
• 19:38
  Speaker 3: a trivial thing, that's not real stress, but for them
• 19:40
  Speaker 3: it could be massive, right, And so situationally you never
• 19:43
  Speaker 3: really know. But people are going through a ton of
• 19:45
  Speaker 3: a ton of stress these days, right, And so that
• 19:47
  Speaker 3: affects your coursal and.
• 19:50
  Speaker 4: Mike, I would sorry. The one thing I'll be throwing
• 19:52
  Speaker 4: there as well is that your previous history can also
• 19:57
  Speaker 4: have a big effect on how you process stimulant stimuli
• 20:01
  Speaker 4: and stimuli in the environment. So what I'm getting at here,
• 20:04
  Speaker 4: if you've been born with adverse childhood experiences.
• 20:09
  Speaker 1: And trauma. Then the amigdal is constantly switched on and you.
• 20:13
  Speaker 4: Are because it's basically scanning the environment for bad shit,
• 20:17
  Speaker 4: So you're hyper vigilant and hyper reactive to stress.
• 20:20
  Speaker 1: I think that that's important, isn't it.
• 20:23
  Speaker 3: Oh, it's this. I'm very spiritual. This planet is a
• 20:28
  Speaker 3: very challenging, uh place to be. I think it's it's
• 20:33
  Speaker 3: for us to advance our souls. But in that aspect,
• 20:36
  Speaker 3: people are dealing with very difficult things at all times,
• 20:38
  Speaker 3: and it starts from childhood and all the way through,
• 20:41
  Speaker 3: and things that may not be very impactful to you
• 20:43
  Speaker 3: may be devastating for others, and they're dealing and we're
• 20:45
  Speaker 3: so So you have to assume in this day and age,
• 20:48
  Speaker 3: besides the environmental stuff, people are dealing with a tremendous
• 20:51
  Speaker 3: amount of stress. So corsos through the roof, hormones are
• 20:54
  Speaker 3: being You know, when you have no testosterone, for specifically
• 20:57
  Speaker 3: for men, you're dope mean is down. You're not regulating
• 21:02
  Speaker 3: that well, you're not synthesizing that well. If you don't
• 21:04
  Speaker 3: have testosterone, you're not breaking it down to estrogen estradial,
• 21:07
  Speaker 3: which then affects your serotonin levels right, your wellness, your
• 21:12
  Speaker 3: feeling of okayeness, right, motivation drive goes down. Now you're
• 21:17
  Speaker 3: affecting progesterone. Things are affecting sexual drive with estrogen. This
• 21:23
  Speaker 3: is compounded onward all the way down, right for men
• 21:27
  Speaker 3: and women. Women's estrogen's thrown off. The bounce is thrown
• 21:31
  Speaker 3: off with endocrine disruption. We know this factually. It's causing
• 21:35
  Speaker 3: more disease. Things like PCOS is very common. I don't
• 21:38
  Speaker 3: know if you've heard this.
• 21:39
  Speaker 4: But it's very common disorder and not horrible, right, horrible disease.
• 21:43
  Speaker 3: It was a disorder for women that we six eight percent,
• 21:47
  Speaker 3: but now I see it in my clients. It's over
• 21:51
  Speaker 3: fifty percent of females that are dealing with this. And
• 21:53
  Speaker 3: it was just misdiagnosed, right, It was misdiagnosed because they
• 21:56
  Speaker 3: thought it was an ovarian disorder when it's really a
• 21:58
  Speaker 3: metabolic disorder, insulin based disorder. And so all of these
• 22:03
  Speaker 3: things are affecting people globally, and it's affecting one their mood.
• 22:08
  Speaker 3: Right Now that people are feeling more flat, they're feeling
• 22:11
  Speaker 3: less motivation, less drive to do things. So even those
• 22:14
  Speaker 3: who are more inclined to maybe do exercise, maybe eat better,
• 22:18
  Speaker 3: maybe go after a particular job. We're not seeing it.
• 22:22
  Speaker 3: People are flat, right, They're just flat to life. They're
• 22:25
  Speaker 3: easily depressed. They put weight on more because when the
• 22:28
  Speaker 3: hormones are not balanced, this is occurring, right, You're you're
• 22:31
  Speaker 3: storing more than burning. It is become an epidemic that
• 22:36
  Speaker 3: I think we're not really addressing because I see when
• 22:39
  Speaker 3: we do address it, people change tremendously.
• 22:44
  Speaker 4: But before we get a bit, before we get into
• 22:48
  Speaker 4: addressing it, I think there's a combinding factor here. I mean,
• 22:52
  Speaker 4: you've given us the pathways by which stress and all
• 22:56
  Speaker 4: these endocrine disruptors are they in affecting hormone that then
• 23:00
  Speaker 4: affect neural transmitters, and particularly you call that certotonin and
• 23:04
  Speaker 4: dopamine and the low mood and the lack of motivation.
• 23:07
  Speaker 4: But this is where it combines, isn't it. Because if
• 23:10
  Speaker 4: I'm coming home from work, I'm feeling fucking tired, I've
• 23:14
  Speaker 4: got no motivation to exercise.
• 23:16
  Speaker 1: I'm feeling shit.
• 23:18
  Speaker 4: I'm not way less likely to exercise, right, I'm way less.
• 23:23
  Speaker 3: Yeah.
• 23:24
  Speaker 4: And then if you're sedentary, you destroy your biology. If
• 23:28
  Speaker 4: you're sedentary, right, this is this is kind of my wheelhouse.
• 23:31
  Speaker 4: If you're moving, yeah, yeah, and then there's the combining
• 23:34
  Speaker 4: effects that when you're sedentary, then it further erodes your
• 23:38
  Speaker 4: neural transmitters that then further affects things.
• 23:41
  Speaker 1: And then and then you feel so shit that you're you're.
• 23:44
  Speaker 4: Reaching for alcohol or food to try and make things better.
• 23:48
  Speaker 4: Effect that affects your sleep, and then you're really fucked.
• 23:52
  Speaker 3: This is what we're dealing with really on a consistent basis. Hey,
• 23:56
  Speaker 3: I've been down that road. Like I said, when I
• 23:58
  Speaker 3: was when I got a residency. My mood was like that.
• 24:01
  Speaker 3: I did not exercise, I started to get depressed, I
• 24:04
  Speaker 3: drank consistently, I did all of these things. This is
• 24:08
  Speaker 3: I have experienced these horrible this horrible path and people
• 24:13
  Speaker 3: are up against it, they really are. And then what's
• 24:17
  Speaker 3: worse is when they go to a clinician to say, hey,
• 24:20
  Speaker 3: what's going something's wrong and they tell them they're normal.
• 24:23
  Speaker 3: This this is the big disconnect I think that we're having. Luckily,
• 24:26
  Speaker 3: you know, word is becoming more prominent in this space,
• 24:32
  Speaker 3: but modern medicine is not doing a good job with this.
• 24:35
  Speaker 3: This is for sure.
• 24:37
  Speaker 4: So may I know, I know several women who have
• 24:43
  Speaker 4: had that, and that misnowhere that HRT is is something
• 24:49
  Speaker 4: that you should be afraid of because of the the
• 24:52
  Speaker 4: risks of brass cancer. I think that study has been
• 24:54
  Speaker 4: well and truly debunked, right And I know in fact,
• 24:59
  Speaker 4: I was having a convers with with a woman and
• 25:01
  Speaker 4: I know pretty well just a week ago, and she
• 25:05
  Speaker 4: was saying that that she's gone on to HRT and
• 25:08
  Speaker 4: her life has completely transformed, completely transformed, right so so,
• 25:14
  Speaker 4: but over here in Australia, I don't know if it's
• 25:17
  Speaker 4: like in the States. She was just going to the
• 25:19
  Speaker 4: doctor and the doctor's like, are you fine, and you
• 25:22
  Speaker 4: know you don't want to be having HRT, And but
• 25:25
  Speaker 4: she went to I told her about a medica and
• 25:29
  Speaker 4: an integrated of what we call integrative medical doctors over
• 25:32
  Speaker 4: here who are more about proactive health. You know, we
• 25:38
  Speaker 4: work in what I call the healthcare system, not the
• 25:41
  Speaker 4: sick care system. I think most physicians and medical professionals
• 25:45
  Speaker 4: work in the sick care system.
• 25:47
  Speaker 3: Right. This is what we were trained. I try not
• 25:51
  Speaker 3: to I look at it this way. When I went
• 25:54
  Speaker 3: to medical school, we were taught diseases. We were taught
• 25:57
  Speaker 3: how do we identify disease and how do we that.
• 26:01
  Speaker 3: We were never taught. Hey, when a person comes in
• 26:04
  Speaker 3: to see you and says, hey, I want to feel
• 26:05
  Speaker 3: the best I ever feel, I want to prevent disease,
• 26:09
  Speaker 3: we had no solution for that. We said go eat
• 26:12
  Speaker 3: well and exercise very vague. We had no real solutions,
• 26:16
  Speaker 3: and they still don't because the system is really built.
• 26:20
  Speaker 3: Over time, it's gotten way worse because of the HMO
• 26:23
  Speaker 3: systems and things that are driven for profit, right pharmaceutical companies,
• 26:28
  Speaker 3: insurance based companies. They end up writing the protocols of
• 26:31
  Speaker 3: which we have to follow. And then when you try
• 26:34
  Speaker 3: to do functional medicine or things outside of that use
• 26:38
  Speaker 3: non synthetic medications, which are extremely crucial for treating hormones,
• 26:44
  Speaker 3: they're not covered right, and the patient is now left
• 26:46
  Speaker 3: to say, hey, my doc said this is going to
• 26:48
  Speaker 3: cost me one hundred bucks a month. I can't afford
• 26:50
  Speaker 3: that I need the synthetic version that's covered on the formulary.
• 26:53
  Speaker 3: But the synthetic one is going to cause you cancer.
• 26:57
  Speaker 3: Modern medicine doesn't really, so over time they go, this
• 27:00
  Speaker 3: is what we have to offer, and this is what
• 27:01
  Speaker 3: you get, and sadly the doctors are so overstressed that
• 27:04
  Speaker 3: they're so used to this they become jaded. And that's
• 27:07
  Speaker 3: where the system is, right, So a lot of people
• 27:09
  Speaker 3: have to go outside the system. And that's how I work.
• 27:12
  Speaker 3: And that's how the functional doctor you're referencing work to
• 27:15
  Speaker 3: actually treat patients properly with the medications and the and
• 27:19
  Speaker 3: the ranges that we need to do inside medicine. They
• 27:21
  Speaker 3: won't do it. They won't allow it.
• 27:23
  Speaker 4: Yeah, and and and I think America is unique in
• 27:27
  Speaker 4: the impact that the insurance companies have on the whole
• 27:30
  Speaker 4: healthcare system. Like it's just see that's another that's a
• 27:33
  Speaker 4: whole nother podcast by by itself. So and so you
• 27:38
  Speaker 4: talked about synthetic and nonsense. So you're told about here.
• 27:40
  Speaker 4: So bioidentical hormones. Tell tell our listeners what bioidentical hormones
• 27:46
  Speaker 4: are and the difference between them.
• 27:48
  Speaker 3: Them and the bioidentical hormones are structures that are identical
• 27:54
  Speaker 3: to our own hormones. So the landmark study you were
• 27:57
  Speaker 3: talking about, the w HI that scare women and malign
• 28:01
  Speaker 3: them for the last twenty plus years, did studies on
• 28:05
  Speaker 3: synthetic estrogen with synthetic progesterone, and these are non identical
• 28:11
  Speaker 3: to your body, So your body makes progesterone, and they
• 28:14
  Speaker 3: have the molecule, they do exactly that chemical molecule. Synthetically,
• 28:18
  Speaker 3: they'd make it something similar that will fit into a
• 28:20
  Speaker 3: receptor and mimic that function, but it never truly mimics it.
• 28:25
  Speaker 3: And the reason why they make synthetic is because you
• 28:29
  Speaker 3: can't patent progesterone, so I can't own progesterone. It's naturally occurring.
• 28:35
  Speaker 3: So I could go to a compounding pharmacy and they
• 28:37
  Speaker 3: will mix it into a pill form, but it will
• 28:40
  Speaker 3: be the pure content. They can't own that, but they
• 28:43
  Speaker 3: can charge me extra for making it because they compounded it.
• 28:46
  Speaker 3: But pharmaceuticals companies cannot make money off of that. Now
• 28:48
  Speaker 3: they can synthesize it and make it synthetic, and they
• 28:51
  Speaker 3: could call it provera, right, and now they can charge
• 28:55
  Speaker 3: whatever they want, and insurance companies will take it on
• 28:57
  Speaker 3: their formulary and then that's what they'll give you. That's
• 29:01
  Speaker 3: the system. That's that's the system in a nutshell. And
• 29:04
  Speaker 3: what they've shown is that sadly, the synthetic will cause
• 29:06
  Speaker 3: all the side effects it will cause cancers. And so
• 29:09
  Speaker 3: that's where the landmark studies were done which said hormones
• 29:12
  Speaker 3: cause cancer, but it was synthetically done hormones. When you
• 29:16
  Speaker 3: look at bioidentical it does the opposite. It doesn't only prevent,
• 29:21
  Speaker 3: it prevents cancers while keeping you health healthy. And so
• 29:24
  Speaker 3: this is the big disconnect because even to me, this is.
• 29:28
  Speaker 4: A mic drop moment for lots of people who might
• 29:32
  Speaker 4: have five ten years ago gone to their doctor or
• 29:35
  Speaker 4: even nigh and their doctor isn't up in the research
• 29:37
  Speaker 4: and are told that hormones can cause cancer. But as
• 29:42
  Speaker 4: you're saying, the research is now showing that the bioidentical
• 29:45
  Speaker 4: ones can prevent it, whereas.
• 29:46
  Speaker 3: It's they've prevented it. They've done studies, they've done they've
• 29:49
  Speaker 3: done very well, double blinded pacebo studies. These are the
• 29:55
  Speaker 3: highest level of studies. They've shown when you take synthetic
• 29:59
  Speaker 3: as rogen and synthetic estrogen, although it's not as good
• 30:03
  Speaker 3: as bioidentical, they haven't shown that that causes cancer. It
• 30:07
  Speaker 3: was to progestin specifically, and when they combined it that
• 30:11
  Speaker 3: studies where they combine it with with synthetic estrogen and
• 30:16
  Speaker 3: and bioidentical estrogen and it only caused cancer in the
• 30:19
  Speaker 3: synthetic uh with with the with the progesterone, when you
• 30:23
  Speaker 3: use normal progesterone, even with synthetic estrogen didn't cause the cancer.
• 30:26
  Speaker 3: So they identified it specifically the progesterone. But we have many,
• 30:30
  Speaker 3: many examples of this. When you use synthetic thyroid, it
• 30:34
  Speaker 3: does not do the same function as bioidentical and it
• 30:38
  Speaker 3: actually prevents downstream productions of other thyroids you need, and
• 30:41
  Speaker 3: so it actually worsens patient's outcomes. But we've this is
• 30:44
  Speaker 3: what we exclusively use in this country. Synthetic.
• 30:48
  Speaker 4: That's crazy, that's crazy. So so so we're on the
• 30:51
  Speaker 4: topic of women. Let's stay on women and name will
• 30:53
  Speaker 4: swamp short and after that so so so, a woman
• 30:58
  Speaker 4: it's not feeling great, it goes to and integrative doctor,
• 31:01
  Speaker 4: like he gets their lab slabs measured. What typically would
• 31:06
  Speaker 4: the I know it will change for the individual, but
• 31:10
  Speaker 4: would you be pro not just looking at progesterone and
• 31:15
  Speaker 4: estrogen but also testosterone and and what is the role
• 31:19
  Speaker 4: of testosterone in women?
• 31:20
  Speaker 1: Because I know some.
• 31:21
  Speaker 4: Who sure has just gone on progesterone easter not on testosterone,
• 31:26
  Speaker 4: and then they've gone to an integrative doctor who's gone, geez,
• 31:29
  Speaker 4: you need to be on some testosterone.
• 31:32
  Speaker 3: I look at the whole picture because I've seen now
• 31:36
  Speaker 3: many many patients, men and women, and like, like I
• 31:41
  Speaker 3: was sit stating, when one hormone is dysfunction, typically it's
• 31:46
  Speaker 3: a cascade effecting album. When we used to think, hey,
• 31:49
  Speaker 3: I go to my doctor, I'm having symptoms of low thyroid,
• 31:52
  Speaker 3: my metabolism slow, I feel tired, I feel weak, maybe
• 31:56
  Speaker 3: I'm losing my hair. We would run tests and we
• 31:58
  Speaker 3: would find that specific problem, and that specific problem only
• 32:02
  Speaker 3: we'd say, hey, you have a thyroid problem. But when
• 32:04
  Speaker 3: I see patients, they have low thyroid, they have dysregulated
• 32:09
  Speaker 3: estrogen progesterone, they have out of control DHA, which is
• 32:14
  Speaker 3: another pro hormone. Their testosterone is in the dump, right,
• 32:19
  Speaker 3: they're vitamin D which is not a vitamin, it's a hormone,
• 32:23
  Speaker 3: is dysfunctional. Right, And so when you see when you
• 32:25
  Speaker 3: see that all of these are dysfunctioned, you start to go, Wow,
• 32:29
  Speaker 3: this is a bigger This is a bigger problem than
• 32:31
  Speaker 3: just an isolated disease process. Right, this is a global
• 32:35
  Speaker 3: system dysfunction. And so I look at people. I always
• 32:39
  Speaker 3: look at everything because they all communicate and work together
• 32:42
  Speaker 3: in some fashion, and I almost never find someone who
• 32:46
  Speaker 3: has perfect anything. This doesn't occur anymore, But I don't
• 32:50
  Speaker 3: find anybody who doesn't have some dysfunction in every aspect.
• 32:55
  Speaker 3: It's just there. And when I when I treat women specifically,
• 32:58
  Speaker 3: I'm always looking for or PCOS. This is so, this
• 33:02
  Speaker 3: is one of the most misdiagnosed and the most troubling
• 33:06
  Speaker 3: for women in the sense if you give me a
• 33:09
  Speaker 3: minute to explain this, you know, polycystic ovarian syndrome was
• 33:12
  Speaker 3: a very specific profile. You had to be overweight, you
• 33:15
  Speaker 3: had to have ovariant cysts, you had to have hair
• 33:19
  Speaker 3: growth from androgenic effects, and acne on your face. So
• 33:22
  Speaker 3: in medical school it gave us a picture of someone
• 33:24
  Speaker 3: this person as PCOS. That's what they always look like,
• 33:27
  Speaker 3: and if they don't, they don't have it. They had
• 33:29
  Speaker 3: dysregulation and menstruation, and they often had infertility right and
• 33:33
  Speaker 3: so forever women were just treated with birth control. You know,
• 33:37
  Speaker 3: you had this regular de menstruation, Well, we think they
• 33:39
  Speaker 3: may have Pcoscue and birth control. This will affect the
• 33:43
  Speaker 3: heavy menstruation and you just have to be infertile for
• 33:45
  Speaker 3: the rest of their life and deal with it. They
• 33:47
  Speaker 3: would have painful cysts. Well, GLP once came out, you know,
• 33:53
  Speaker 3: things like ozampic and these GLP ones came out, and
• 33:55
  Speaker 3: patients started taking them, as of course they're obese to
• 33:58
  Speaker 3: taking these medications. And in this name, we had an
• 34:00
  Speaker 3: explosion in women in their forties getting pregnant massively, yeah, massively.
• 34:06
  Speaker 3: And they called it ozebic babies. You can google this.
• 34:09
  Speaker 3: It was becoming freely yeah yeah, yeah, and so and
• 34:13
  Speaker 3: and so we said, what is going on here? How
• 34:16
  Speaker 3: can these women who were pcos infertile. My wife's cousin
• 34:21
  Speaker 3: was one of these women, forty four years old, never
• 34:23
  Speaker 3: had a baby, told she was infertile, got on GLP one.
• 34:26
  Speaker 3: Within a year she had a baby.
• 34:29
  Speaker 1: Surprise, surprise.
• 34:32
  Speaker 3: Wow, crazy stuff, right, Oh, I mean this is not
• 34:37
  Speaker 3: necessarily good news for everybody, but this was happening, right,
• 34:41
  Speaker 3: And so they looked and they said, wow, this is
• 34:44
  Speaker 3: a metabolic disorder. This is not this is not what
• 34:47
  Speaker 3: we thought this was. And so when I see patients,
• 34:51
  Speaker 3: I have to assume they have this thing at all times.
• 34:53
  Speaker 3: This is how I was trained. Because you now can
• 34:56
  Speaker 3: have pcos and be thin, not obese. You can I've
• 35:00
  Speaker 3: had children, five children, you can have regular menstruation. This
• 35:04
  Speaker 3: doesn't fit the picture at all, But you have an
• 35:06
  Speaker 3: insulin resistance at such a low level that it can
• 35:09
  Speaker 3: cause dysfunction in your thyroid. It can cause a disproportionate
• 35:14
  Speaker 3: ratio to your progesterone to estrogen, which may not be
• 35:17
  Speaker 3: bad enough to cause anovulation, right, not having ovulation and
• 35:20
  Speaker 3: things or better set pregnancy embedding. But it will throw
• 35:27
  Speaker 3: off your mood, It will throw off your sleep, It
• 35:31
  Speaker 3: will put you in a position to have more estrogen
• 35:33
  Speaker 3: to progesterone that puts you at a risk of cancer. Right.
• 35:37
  Speaker 3: Unopposed estrogen causes cancer. And so when I look at patients,
• 35:41
  Speaker 3: I have to look at this. If I give testostera
• 35:43
  Speaker 3: to a female on PCOS, they can have over the
• 35:47
  Speaker 3: top reaction to it because the PCOS they have a
• 35:51
  Speaker 3: low protein that carries testosterone, and that testosterone is not
• 35:55
  Speaker 3: there to carry it. So they have a higher percentage
• 35:57
  Speaker 3: of the free testosterone that's available, and hence they have
• 36:00
  Speaker 3: the hair growth, they have the acne. Right, So they
• 36:02
  Speaker 3: may have a very low total, but they're free testosterone
• 36:06
  Speaker 3: is much higher percentage wise than it should be. And
• 36:09
  Speaker 3: so all these subtle things. But when I see patients,
• 36:13
  Speaker 3: I always look at them globally, and I always look
• 36:16
  Speaker 3: to first make sure we don't have this condition, and
• 36:19
  Speaker 3: then we treat each thing individually, sequentially.
• 36:24
  Speaker 4: And Mike is, so, is p coos driven by inchulin resistance?
• 36:29
  Speaker 4: Is that the major driver?
• 36:31
  Speaker 3: Well? PCs used to be thought to be a genetic
• 36:36
  Speaker 3: condition you passed on, right, six to eight percent of
• 36:39
  Speaker 3: the female population had it, and this is what was
• 36:41
  Speaker 3: passed on. Now we see and the Anercrinto Society specifically
• 36:46
  Speaker 3: spoke about in twenty fifteen that PCUS is being caused
• 36:50
  Speaker 3: by endocrine disruption. So I don't know if that's I
• 36:53
  Speaker 3: don't know if if the spectrum is being widened, meaning
• 36:56
  Speaker 3: we have patients who've had babies or those women were
• 37:00
  Speaker 3: not pcos and they've accumulated so much dysfunction that now
• 37:04
  Speaker 3: they are PCUS. It's really hard to say, right, but
• 37:07
  Speaker 3: it is. It is treated insulin based, So first we
• 37:10
  Speaker 3: treat insulin resistance. We treat it with either GLP ones
• 37:14
  Speaker 3: are generally the best thing, or met format can work,
• 37:17
  Speaker 3: although higher doses are difficult for people to tolerate, and
• 37:21
  Speaker 3: then we work on that the actual source of the problem.
• 37:25
  Speaker 3: While we're giving back the hormones that a bit dysfunctioned.
• 37:28
  Speaker 4: Gotcha, gotcha, But the upstream, the upstream villain of the
• 37:32
  Speaker 4: pace tends to be high insulin.
• 37:35
  Speaker 3: Well, and this is the thing, Paul, Like, you know
• 37:39
  Speaker 3: what we consider to be insulin resistance, right, we have
• 37:42
  Speaker 3: we have a few tests that we check, right, so
• 37:44
  Speaker 3: your glucose is a certain amount. Yeah, okay, this is
• 37:46
  Speaker 3: starting to get bad. And we check your hemoglobe in
• 37:49
  Speaker 3: a one C. Right, this is like the span of
• 37:51
  Speaker 3: of your red blood cells the hemoglobe, and a one
• 37:53
  Speaker 3: C helps kind of tell us where your sugars have
• 37:55
  Speaker 3: been for the one hundred and twenty games. Right, But
• 38:00
  Speaker 3: that just tells us if we have full blown diabetes. Right,
• 38:03
  Speaker 3: Diabetes is a disastrous systemic problem. Yeah, when we're talking
• 38:08
  Speaker 3: about insulin resistance for PCOS, we what we found is
• 38:12
  Speaker 3: that women would have a perfect humo globe in a
• 38:14
  Speaker 3: one CE four point seven on our scale, which is
• 38:17
  Speaker 3: perfect the lowest you could have on the test on
• 38:20
  Speaker 3: the scale, and yet they have full blown PCOS, right,
• 38:23
  Speaker 3: which is an insulin resistance disease. And so it's letting
• 38:26
  Speaker 3: us know that one that's a terrible marker for telling
• 38:29
  Speaker 3: us if we have insulin resistance and people are having
• 38:31
  Speaker 3: disease processes under that marker. So it just it just
• 38:35
  Speaker 3: tells me when I look at that marker, I just say, hey,
• 38:37
  Speaker 3: do you have diabetes or not.
• 38:38
  Speaker 1: It doesn't tell me anything else that's interesting.
• 38:41
  Speaker 4: And it reminds me of a decade ago I was
• 38:44
  Speaker 4: working when I was doing an original pH day which
• 38:48
  Speaker 4: I ended up switching. But my supervisor was a doctor
• 38:53
  Speaker 4: and a researcher, and we were talking about metabolic that
• 38:55
  Speaker 4: might have metabolic syndrome, which for the listeners is a
• 38:59
  Speaker 4: is a luster of unhealthy conditions such as high waist circumference,
• 39:04
  Speaker 4: high trick lesterides, low hits, d l M. But but
• 39:08
  Speaker 4: and she took the high fasting blood glucose, she said,
• 39:13
  Speaker 4: she and high blood pressure. So three of five depending
• 39:16
  Speaker 4: on who you listen to, you right, but sure, And
• 39:19
  Speaker 4: she said to me, glucose is always.
• 39:21
  Speaker 1: The last to go.
• 39:23
  Speaker 4: She says, you know, you will have somebody who's got
• 39:27
  Speaker 4: normal glucose and they think they're okay, but they have
• 39:30
  Speaker 4: rampant metabolic dysfunction.
• 39:33
  Speaker 3: Because glucose balance is so crucial. Right, So the body
• 39:37
  Speaker 3: is the body. The body is is very brilliant, right,
• 39:40
  Speaker 3: it's amazing, and it can deal with so many insults,
• 39:43
  Speaker 3: and it prioritizes I have to keep this in this range,
• 39:46
  Speaker 3: and it will be fantastic at doing that despite the
• 39:50
  Speaker 3: chaos going on, until it's over the edge, and it's
• 39:54
  Speaker 3: not a gradual descent, it's you fall off a cliff. Right.
• 39:57
  Speaker 3: You've seen people who you go, oh my god, gym
• 39:59
  Speaker 3: was fine. He was fine all of a sudden. Now
• 40:01
  Speaker 3: he's now he's on a ventilator. He's he's not gonna
• 40:04
  Speaker 3: make it. Because when the body can handle insult so well,
• 40:08
  Speaker 3: and then when it doesn't, it's not a gradual oftentimes
• 40:11
  Speaker 3: it's a total collapse. Right. And so the same with
• 40:13
  Speaker 3: the glucose. It's keeping that because it's so crucial for
• 40:16
  Speaker 3: for so many functions of our cellular level to keep
• 40:19
  Speaker 3: that in a normal range until Okay, now we're now
• 40:22
  Speaker 3: we're in trouble. Now we're in trouble when.
• 40:25
  Speaker 4: When when your glucost goes, you've got way bigger problems
• 40:29
  Speaker 4: than just high blood sugar.
• 40:30
  Speaker 1: You've got rumpant metabolic dysfunction.
• 40:32
  Speaker 3: Right, and it's been going on for a while. It's
• 40:35
  Speaker 3: not it's not been going on for a year or two.
• 40:37
  Speaker 3: It's been going on for years.
• 40:39
  Speaker 4: So so when you are then treating women mic whether
• 40:42
  Speaker 4: whether they have p c s or they don't have
• 40:44
  Speaker 4: two s, and is there a typical formula like are
• 40:48
  Speaker 4: they generally going on to pro progsterone and estrogen and testosterone.
• 40:55
  Speaker 1: Or you know what's more? What's more so?
• 40:58
  Speaker 3: And I think in America when I see women, the
• 41:03
  Speaker 3: debate is estrogen, right, And so most of the women
• 41:09
  Speaker 3: that come to me, if they're pre metopausal meaning forties,
• 41:13
  Speaker 3: they're not even hitting metopausal perimetopausal symptoms and perimetopausal, they're
• 41:20
  Speaker 3: they're maybe getting swings in their estrogen as there as
• 41:23
  Speaker 3: their stimulation is going down in their production, and so
• 41:26
  Speaker 3: they're getting spikes of estrogen and decrease as they're getting
• 41:28
  Speaker 3: into metopause. These women specifically progesterone almost always thyroid and
• 41:36
  Speaker 3: testosterone if they don't have pcos. If you have pcos,
• 41:40
  Speaker 3: then you got to slow down on the testosterone. Do
• 41:42
  Speaker 3: you correct some of that, because otherwise you're going to
• 41:44
  Speaker 3: give them way too much androgen and they're going to
• 41:47
  Speaker 3: end up with acne and hair growth and irritability. So
• 41:50
  Speaker 3: you have to be careful about that. A lot of clinics.
• 41:53
  Speaker 3: I get a lot of women who come and they've
• 41:55
  Speaker 3: they're on testoga. They feel totally manic and upset and
• 41:59
  Speaker 3: they're acne and understand what's going on, and they're gonna
• 42:01
  Speaker 3: look like a.
• 42:03
  Speaker 4: European Eastern European athlete from the female lasthlete from the
• 42:07
  Speaker 4: nineteen exactly.
• 42:09
  Speaker 3: This is what happens because even a little bit, even
• 42:11
  Speaker 3: a baby dose, right, we're using a fraction of what
• 42:14
  Speaker 3: men use. Even that small much amount is too much
• 42:17
  Speaker 3: for their system. And so but also as crucial as
• 42:21
  Speaker 3: the modality, right, UH, progesterone specifically, I give orally oral progesterone.
• 42:27
  Speaker 3: Know there's a lot of people that use patches and
• 42:29
  Speaker 3: they use creams. Right, this is crucial, UH information. Progesterone
• 42:35
  Speaker 3: can cross the blood brain barrier if given orally the
• 42:38
  Speaker 3: breakdown product and if you don't give orally and it
• 42:41
  Speaker 3: makes you sleepy, so that that dose has to be
• 42:43
  Speaker 3: at night, but it will go into the brain. Excellent
• 42:47
  Speaker 3: studies show that it will help with Alzheimer's disease and dementia,
• 42:50
  Speaker 3: but it helps with mood stabilization.
• 42:52
  Speaker 1: UH.
• 42:53
  Speaker 3: In all the studies on progesterone the quintessential responses. It
• 42:58
  Speaker 3: made people have a sense of well being. I don't
• 43:01
  Speaker 3: know many things that make people have an increased sense
• 43:03
  Speaker 3: of well being, but progesterone is one of them. And
• 43:06
  Speaker 3: when in order to tell you.
• 43:07
  Speaker 4: That it's in order to tell you that it's got
• 43:09
  Speaker 4: across the bloodbream barrier, it's got.
• 43:10
  Speaker 3: Across the blodbreing bear. The other effects, you have plenty
• 43:13
  Speaker 3: of the other effects cardiovasterly obviously on the uterine lining,
• 43:17
  Speaker 3: which is crucial. You have to balance with estrogen otherwise, again,
• 43:20
  Speaker 3: unopposed estrogen can cause cancers. It causes growth of the
• 43:24
  Speaker 3: uterine lining. And this is why progesterone should always be given,
• 43:28
  Speaker 3: no matter if you have a uterus or not. Right
• 43:30
  Speaker 3: that the old edict was, Hey, you don't have a uterus, dummy,
• 43:33
  Speaker 3: why are you giving this woman progestero edemmetrial tissue? Besides
• 43:37
  Speaker 3: the systemic effects of progesterone, that works outside the uterus,
• 43:40
  Speaker 3: which is crucial, right, But estrogen or eneometro tissue oftentimes
• 43:45
  Speaker 3: is outside the uterus. Right, Women have enometriosis, many don't
• 43:49
  Speaker 3: even know they have it, right, And sadly, medicine has
• 43:53
  Speaker 3: given these women cancer by giving them just estrogen without progesterone. Position,
• 43:58
  Speaker 3: you should never have You should never be replaced on
• 44:00
  Speaker 3: purely estrogen without progesterone. Balance. This is a number one rule, right,
• 44:05
  Speaker 3: This is this is this is very dangerous, but predominantly
• 44:09
  Speaker 3: most of my women. Yes, I I almost never see
• 44:13
  Speaker 3: a woman who doesn't benefit from a low dose of testosterone. Yeah,
• 44:17
  Speaker 3: testosterone will help with vaginal health as well as motivation,
• 44:20
  Speaker 3: drive libido, things like this, and we could do it
• 44:25
  Speaker 3: in creams or nowadays women are wanting injectables. I don't
• 44:28
  Speaker 3: understand why, but they do. But the creams are very
• 44:31
  Speaker 3: effective as well. And then for estrogen when we do
• 44:35
  Speaker 3: give it, which is in the perimetal puzzle, if the
• 44:38
  Speaker 3: symptoms cannot be controlled with with project high doses of progesterone,
• 44:42
  Speaker 3: or they're getting symptoms of low estrogen bone aching and
• 44:45
  Speaker 3: real really bad, really bad emotional swings that we can't
• 44:50
  Speaker 3: manage with the progesterone, then we will add the estrogen.
• 44:53
  Speaker 3: We just have to make sure the progesterone is in
• 44:55
  Speaker 3: protective levels to do that, and then that way, But
• 44:58
  Speaker 3: again that's given orally as well well, because the studies
• 45:01
  Speaker 3: have shown that oral oral, and this is all micronized, compounded, bioidentical, right,
• 45:08
  Speaker 3: I'm not talking about synthetic stuff. Shows that has a
• 45:11
  Speaker 3: better protection cardiovascularly, right. And so when we look at
• 45:15
  Speaker 3: women cardiovascularly, you know, prior to metopause, women have three
• 45:20
  Speaker 3: hundred percent or better less incidence of heart attack than men. Right,
• 45:25
  Speaker 3: So men have a three hundred percent in higher risk
• 45:27
  Speaker 3: of heart attack. As soon as we have metopause, they
• 45:30
  Speaker 3: can play risk estrogen. Estrogen is protective cardiovascularly, and so
• 45:37
  Speaker 3: when people hit menopause, we want to make sure that
• 45:40
  Speaker 3: we're getting the cardiovascular protection because it's a huge mortality risk, right,
• 45:44
  Speaker 3: And so nothing will increase three hundred percent, right. Uh,
• 45:48
  Speaker 3: but if you give women estrogen in metopause, you get
• 45:53
  Speaker 3: that back, right. And so the but the one that
• 45:55
  Speaker 3: shows the most effectiveness in doing this is oral. Right.
• 45:58
  Speaker 1: That's interesting. So or for both progesterone and estrogen.
• 46:03
  Speaker 4: And now you mentioned there the effects of progesterone on Alzheimer's.
• 46:09
  Speaker 4: I recently am I was listened to an expert on
• 46:13
  Speaker 4: hormones talking about estrogen and the effects on reducing alzhemer
• 46:18
  Speaker 4: And apparently the Brian is riddled with estrogen receptors right
• 46:23
  Speaker 4: all over the tricking Brian, And for me it's like,
• 46:26
  Speaker 4: but the neuroscience background, if there's receptors in there, that
• 46:29
  Speaker 4: shit's needed.
• 46:30
  Speaker 3: Right. Hormones are everywhere, you know, when you think about
• 46:34
  Speaker 3: where the receptors for hormones, it's it's everywhere really, how
• 46:38
  Speaker 3: it communicates, and how globally important it is. And estrogen,
• 46:43
  Speaker 3: I mean for men, For many years estrogen was blocked right, yes,
• 46:48
  Speaker 3: in these spaces I mean, and we've caused heart attacks
• 46:52
  Speaker 3: and osteoporosis and strokes and all these things because we
• 46:56
  Speaker 3: did not understand the importance of estrogen and it's crucial
• 47:00
  Speaker 3: paramont so much so that there's excellent research showing that
• 47:04
  Speaker 3: when we replace testosterone in men, there will be there
• 47:08
  Speaker 3: will be a part. Usually I wait about a year
• 47:10
  Speaker 3: to let it balance out to see where we're at
• 47:12
  Speaker 3: that we're going to need to replace men on estra
• 47:15
  Speaker 3: dial So I have I do this personally. When you're
• 47:19
  Speaker 3: on testosterone and then you supplement with estra dile to
• 47:22
  Speaker 3: get the levels in a more protective way for your
• 47:25
  Speaker 3: cardiovascular for your brain, right, protect protecting strokes and heart
• 47:28
  Speaker 3: attacks and Alzheimer's. This is this is factual stuff that
• 47:31
  Speaker 3: they're finding, and so we don't block it. We add
• 47:35
  Speaker 3: it's so important.
• 47:37
  Speaker 4: Okay, So so well that's a good segue to go
• 47:40
  Speaker 4: from from women to man. And and I think hormone
• 47:44
  Speaker 4: replacement therapy, certainly in this country is is is way
• 47:48
  Speaker 4: less talked about.
• 47:49
  Speaker 1: In man than it is in women.
• 47:51
  Speaker 4: And unless you know, people are on that edge of longevity,
• 47:56
  Speaker 4: but your average individual is really not thinking about it.
• 48:00
  Speaker 1: So let's talk about man's health.
• 48:04
  Speaker 4: You know, I think that the whole midlife crisis is
• 48:07
  Speaker 4: kind of summed up by andropause. I think a lot
• 48:10
  Speaker 4: of men don't realize we have an equivalent to menopause,
• 48:14
  Speaker 4: which is called andropause. You know, low growth hormone, testosterone
• 48:18
  Speaker 4: deity A. And that's going to make it be pretty shit, right,
• 48:22
  Speaker 4: talk us through, sure, what you typically see more of,
• 48:28
  Speaker 4: like is it is it just the low.
• 48:30
  Speaker 1: Testosterone on itself? What's the impact on growth hormone on
• 48:34
  Speaker 1: d it? And then you know.
• 48:36
  Speaker 4: Assessing and treatment. But let let's let's talk about symptoms first.
• 48:41
  Speaker 3: Sure, So you know, I know, I know personally, right,
• 48:47
  Speaker 3: you get low first starts like low energy, right, but
• 48:51
  Speaker 3: this is hard to define, right, everybody has low energy
• 48:53
  Speaker 3: in the society for the most part. Right, it can
• 48:56
  Speaker 3: affect your sleep. Yes, it starts to affect your motivation,
• 49:01
  Speaker 3: not just in doing new things, but in doing things
• 49:03
  Speaker 3: you enjoyed in the past. You just become flat. You're
• 49:06
  Speaker 3: just like indifferent almost right. It will absolutely affect your libido.
• 49:11
  Speaker 3: It can affect sexual function. If it gets grave enough, right,
• 49:16
  Speaker 3: you will lose uh, muscle tone, you'll lose inability to
• 49:21
  Speaker 3: put on muscle effectively, and you will gain more fat easily. Right,
• 49:26
  Speaker 3: So you get it, you get the opposite. The fat
• 49:28
  Speaker 3: percentage goes up. But brain thought, right, you're just forgetting
• 49:33
  Speaker 3: things like what's that? Why did I forget? Where the
• 49:35
  Speaker 3: hell's my keys? But it becomes more consistent. You're forgetting
• 49:37
  Speaker 3: simple things. I kind of define it like it's like
• 49:42
  Speaker 3: a veil kind of overa that's cloudy. You can kind
• 49:45
  Speaker 3: of see. But things are becoming a little less clear
• 49:49
  Speaker 3: a little bit. You're becoming a little bit slower, right,
• 49:52
  Speaker 3: and you become almost indifferent. When it gets really bad,
• 49:56
  Speaker 3: you lose a sense of who you are completely, uh,
• 49:59
  Speaker 3: and you're just kind of going through the day. You're
• 50:01
  Speaker 3: in survival mode. Paul, that's where you go right when
• 50:03
  Speaker 3: it gets really bad, you're in pure survival mode. And
• 50:06
  Speaker 3: so when I see men come in, it used to
• 50:09
  Speaker 3: be that we would see this. Yes, of course, you
• 50:12
  Speaker 3: have a normal degredation in your hormone production as you
• 50:17
  Speaker 3: as you age, right, this is standard. So a twenty
• 50:20
  Speaker 3: year old should not have the same testosterone as an
• 50:22
  Speaker 3: eighty year old. We know this. But what we're seeing
• 50:27
  Speaker 3: is that twenty year olds are having eight year old
• 50:30
  Speaker 3: numbers now, right, and so this is a top of
• 50:34
  Speaker 3: maybe a normal degredation that would cause Andrew pause in
• 50:39
  Speaker 3: the late forties. We're seeing I'm seeing guys who's who
• 50:45
  Speaker 3: They bring me their son. They're like, you know, I
• 50:46
  Speaker 3: don't treat children because there's no there's no indication we've
• 50:49
  Speaker 3: not been This is like the wild West now. But
• 50:52
  Speaker 3: I see eighteen year olds are coming to me with
• 50:54
  Speaker 3: testosterones in the two hundreds from men that I treat,
• 50:57
  Speaker 3: and they want me to look at their son.
• 50:58
  Speaker 1: And so it's true, what's what's your levels be? I think?
• 51:02
  Speaker 3: And you know, take take what it used to be
• 51:06
  Speaker 3: forty years ago. When you're hitting the peak of your
• 51:09
  Speaker 3: testosterone production in you're seventeen eighteen years old, right, you're
• 51:14
  Speaker 3: you're you're somewhere around twelve hundred to fifteen hundred, Paul,
• 51:18
  Speaker 3: and these these guys are rocking two hundred, right and so.
• 51:23
  Speaker 3: Men men in the in the seventies and eighties had
• 51:26
  Speaker 3: testosterone nine hundred, eleven hundred, twelve hundred. Most men in
• 51:30
  Speaker 3: their forties now are coming to me with three hundred,
• 51:34
  Speaker 3: right and so, And the studies show that from the
• 51:39
  Speaker 3: set this goes back to the early eighties. I think
• 51:41
  Speaker 3: this has been going on longer. We have over one
• 51:44
  Speaker 3: it's almost up to one and a half percent decrease
• 51:47
  Speaker 3: in testosterone. You know, the beginning years were one hundred
• 51:50
  Speaker 3: and it's getting one percent and it's gotten worse. So
• 51:53
  Speaker 3: we're well over fifty percent less than when we were
• 51:56
  Speaker 3: forty years ago. This is this and that's minimal. I'm
• 52:00
  Speaker 3: being way worse than that on paper. And it's affecting
• 52:04
  Speaker 3: sperm count. Right, we talk about how men are being
• 52:06
  Speaker 3: affected hormonally sperm count. From the seventy they did two
• 52:09
  Speaker 3: great studies. It's the Vine Study. They did massive studies
• 52:13
  Speaker 3: and not just America, it was in Europe and a
• 52:16
  Speaker 3: few other nations where they showed that sperm count was
• 52:19
  Speaker 3: going down one point six percent from seventies to twenty ten,
• 52:23
  Speaker 3: and then from two thousand to twenty twenty two. I
• 52:26
  Speaker 3: think they did another study and they said it's two
• 52:29
  Speaker 3: point six percent now, right, year over year. You do them,
• 52:33
  Speaker 3: if you do the math, it's not you know, we're
• 52:36
  Speaker 3: like seventy percent down in sperm count. Right. This is
• 52:39
  Speaker 3: not a normal just not a normal thing going on.
• 52:42
  Speaker 3: And it's not just hormonally based. It's from the endercondisruption,
• 52:45
  Speaker 3: the plastics and all this that they know is affecting
• 52:47
  Speaker 3: this and so I see, men, I have to look
• 52:51
  Speaker 3: at the symptoms. This is what's you know. I love labs,
• 52:54
  Speaker 3: they're very useful, but all the studies show when you're
• 52:57
  Speaker 3: treating people hormonally, you have to listen to their symptoms
• 53:01
  Speaker 3: and you have to make sense of that when you're
• 53:03
  Speaker 3: treating them, not just look at the numbers, because again
• 53:05
  Speaker 3: the numbers, if you look at the reference ranges, they're
• 53:08
  Speaker 3: of the average population. But in the studies when they
• 53:11
  Speaker 3: do the studies, and they're excellent studies, and they treat
• 53:13
  Speaker 3: people based on symptomatology, when people get better, they're almost
• 53:18
  Speaker 3: always outside of the normal ranges, almost always as in
• 53:21
  Speaker 3: the as in the higher right when they go, We're
• 53:25
  Speaker 3: not going to treat on numbers. We're just going to
• 53:26
  Speaker 3: say how does the patient do Let's get them better symptomatically,
• 53:31
  Speaker 3: and when they do, it's almost always outside the ranges
• 53:33
  Speaker 3: and every aspect.
• 53:35
  Speaker 4: Wow, And to your point, they kind of not quite
• 53:39
  Speaker 4: the opposite. But some people can feel okay on reasonably
• 53:44
  Speaker 4: low testosterone, can't they?
• 53:46
  Speaker 1: It is is that right?
• 53:49
  Speaker 3: Okay?
• 53:49
  Speaker 4: And so why the symptoms? That's why the symptoms are important.
• 53:53
  Speaker 3: The symptoms are crucial because this is you know, I
• 53:58
  Speaker 3: go on a lot of podcasts with you know, people
• 54:00
  Speaker 3: who are very into the numbers. They want the labs.
• 54:03
  Speaker 3: What do I need to do? What lab do I
• 54:04
  Speaker 3: need to be at? Because a lot of these people
• 54:06
  Speaker 3: are going out on their own and doing it. But
• 54:08
  Speaker 3: the reality is there's no there's no number.
• 54:10
  Speaker 1: I can tell you.
• 54:10
  Speaker 3: This is where the perfect number is, Like, no, it's
• 54:13
  Speaker 3: all based on how your symptoms are resolving. And for
• 54:16
  Speaker 3: some one thousand testosterone changes their world and other people
• 54:20
  Speaker 3: there doesn't matter. You need twenty five hundred to get
• 54:24
  Speaker 3: them to feel normal again, and you have. So it's
• 54:28
  Speaker 3: such a spectrum. You have to listen to the patients.
• 54:31
  Speaker 3: You have to see what their symptoms coming in are
• 54:33
  Speaker 3: and how they're improving. Uh, and then that's how you
• 54:36
  Speaker 3: treat it. It's tricky. Hormones are very tricky to treat
• 54:39
  Speaker 3: of that aspect, right, But it's global. You got to
• 54:41
  Speaker 3: look globally at the person, which doesn't do anymore.
• 54:45
  Speaker 4: So when we're talking about interventions, Mike, and is there
• 54:51
  Speaker 4: any member a doctor telling me that that that if
• 54:54
  Speaker 4: somebody is just border lying that they would rather and
• 55:00
  Speaker 4: then go hardcore straight into testosterone, that they might start
• 55:04
  Speaker 4: with DHA because DHA can stimulate the conduction of testosterone.
• 55:10
  Speaker 1: Is that a valid thing?
• 55:12
  Speaker 4: Because is it or is this not true that once
• 55:15
  Speaker 4: you're on testosterone replacement therapy as a bloke, you're pretty
• 55:19
  Speaker 4: much on it because if you compelling me bodybuilders, if
• 55:23
  Speaker 4: you take high decision. I know several bodybuilders who were
• 55:27
  Speaker 4: on testosterone.
• 55:28
  Speaker 1: When they were younger.
• 55:29
  Speaker 4: They completely fucked themselves up and now are on testosterone
• 55:33
  Speaker 4: replacement therapy for the rest of their life.
• 55:35
  Speaker 3: So you know, when we're talking about doing this, we're
• 55:39
  Speaker 3: talking about keeping we're not doing super physiological right, so
• 55:43
  Speaker 3: we're we're replacing what is necessary to get the symptomatology resolved.
• 55:47
  Speaker 3: You know, we talk about replacement. I when I see
• 55:51
  Speaker 3: patients and we say, where are the ranges that people
• 55:54
  Speaker 3: used to be to where they are and how do
• 55:55
  Speaker 3: we How big is that gap? And the gap has
• 55:58
  Speaker 3: gotten to where we're talking six hundred to one thousand
• 56:04
  Speaker 3: percent gap, right, and so we're not talking about so
• 56:09
  Speaker 3: I wish it was the case where I wish we
• 56:10
  Speaker 3: weren't in an environment where this was happening. Supplementation, we
• 56:14
  Speaker 3: would just give you a little and say, hey, we
• 56:16
  Speaker 3: just need to give you a little, Paul, just to
• 56:18
  Speaker 3: get you back into that range. The reality is, and
• 56:21
  Speaker 3: all the studies show this, and when I treat my patience,
• 56:23
  Speaker 3: this is the case. We start low and unfortunately you
• 56:28
  Speaker 3: don't get effect until you get into ranges that are four, five, six,
• 56:33
  Speaker 3: seven hundred percent from where they are because people are
• 56:35
  Speaker 3: so dysfunctional now, right, when we talk about free testosterones,
• 56:39
  Speaker 3: you know, you know there's good numbers to show where
• 56:43
  Speaker 3: people should be to get better. People are coming in
• 56:46
  Speaker 3: with free testosterones of three, four or five for men
• 56:49
  Speaker 3: where they should be high thirties. Right, So if I
• 56:53
  Speaker 3: give you something, Paul, that will double your testosterone naturally. Right,
• 56:57
  Speaker 3: you say, wow, shit, I doubled my testosterone. This is great.
• 57:00
  Speaker 3: I went up one hundred percent, Paul, I must be fantastic.
• 57:04
  Speaker 3: It doesn't do shit. It doesn't do it because you're
• 57:06
  Speaker 3: deficient seven hundred percent. Right. And so that's what people
• 57:10
  Speaker 3: don't get, that that we've gotten to a state of
• 57:13
  Speaker 3: where this disease process really going on in our bodies
• 57:17
  Speaker 3: is so dysfunctional for most that supplementing with just little
• 57:21
  Speaker 3: bits doesn't help. Now, there are, of course, everybody's different.
• 57:25
  Speaker 3: There are some patients that they don't need. They can
• 57:29
  Speaker 3: carry a low low testosterone, but they have a high
• 57:33
  Speaker 3: free and so for them.
• 57:35
  Speaker 1: Can you talk about the difference?
• 57:37
  Speaker 4: Place might just explain this the people between bind and
• 57:40
  Speaker 4: unbind and sure.
• 57:41
  Speaker 3: So, so your total testosterone is, for all intents and
• 57:44
  Speaker 3: purposes in the in this space, almost useless to me
• 57:48
  Speaker 3: in the sense that it's not what's bioavailable. It's not
• 57:51
  Speaker 3: what's going to react with receptors. It's not going to
• 57:55
  Speaker 3: get intercellarly, it's not going to break down into extra
• 57:58
  Speaker 3: dial and DHD. It's for all intensive purposes being carried
• 58:01
  Speaker 3: around by proteins. Right, there's albumen there's SHPG. It's a
• 58:06
  Speaker 3: sex hormone binding clobin that holds onto it, and we
• 58:08
  Speaker 3: call it it's sequestered. It's not allowed to be used, right,
• 58:11
  Speaker 3: And so unless you look at the free, the free
• 58:14
  Speaker 3: is what's unbound. This is the one that's gonna connect
• 58:17
  Speaker 3: to receptors. This one's gonna break down to estradyl DHT
• 58:20
  Speaker 3: and get interscelluarly, this is what your body is using testosterone.
• 58:26
  Speaker 3: And so you can have client patients who they have
• 58:30
  Speaker 3: a higher SHBG, they have higher albumens and although they
• 58:33
  Speaker 3: have a very high total, they're free may be still
• 58:39
  Speaker 3: low because they're binding it all right. You may have
• 58:42
  Speaker 3: someone with a very low testosterone total, but they don't
• 58:46
  Speaker 3: have those proteins and so now they have a very
• 58:48
  Speaker 3: high free and so they feel better, right. And so
• 58:52
  Speaker 3: just looking at the total, you can't really determine how
• 58:56
  Speaker 3: people are gonna do. You have to see what that
• 58:59
  Speaker 3: free is. And then but it gets even more complicated
• 59:02
  Speaker 3: because as people put on more weight, they throw off
• 59:06
  Speaker 3: the distribution of the SHPG. This this throws everything off, right,
• 59:11
  Speaker 3: And what's funny is that the most important component of
• 59:15
  Speaker 3: what hormones do for people is they decrease insulin resistance.
• 59:19
  Speaker 3: This is massive, right, and this is why it's a
• 59:21
  Speaker 3: longevity medicine. It'll make you feel great, it'll make you
• 59:25
  Speaker 3: look strong, but long term, because of the insulin resistance
• 59:30
  Speaker 3: that is suppressing, that's where all the disease process prevention comes.
• 59:34
  Speaker 3: It helps. Obviously, estra diyal helps with cardiovascro stuff and
• 59:37
  Speaker 3: strokes and hard tugs, but long term insulin resistance. There's
• 59:40
  Speaker 3: nothing better that can do this than a functioning thyroid,
• 59:43
  Speaker 3: than a functioning testosterone, progesterone, estrogen. These are known globally
• 59:48
  Speaker 3: to do this, and anecdotically you can kind of see
• 59:51
  Speaker 3: it right when you look at patients. When we were younger,
• 59:56
  Speaker 3: people from the beaches, we were thin. Most people were thin.
• 59:58
  Speaker 3: OBC was not what it is now. It is rampant,
• 1:00:01
  Speaker 3: at least in this nation. It's absolutely rampant. And it's
• 1:00:04
  Speaker 3: not just patient people are lazy. Right, that's so simple,
• 1:00:08
  Speaker 3: such a simplistic answer. There's a component to that, but
• 1:00:11
  Speaker 3: that's also hormonally driven, as the food more fattening shore
• 1:00:15
  Speaker 3: to some extent. However, for the masses to have such
• 1:00:18
  Speaker 3: a large explosion in just a couple of decades No, No,
• 1:00:23
  Speaker 3: there's something physiologically, biochemically going on, and it is the
• 1:00:27
  Speaker 3: dysfunction and the hormones decreasing your metabolism and decreasing insulin
• 1:00:31
  Speaker 3: resistance protection. And this is happening. And when we get
• 1:00:35
  Speaker 3: people fixed, when I give them back what's distorted, their
• 1:00:39
  Speaker 3: body composition changes, and then they change in so many ways,
• 1:00:43
  Speaker 3: in so many ways. And so I wish I was
• 1:00:45
  Speaker 3: a long answer to your question. I wish that I
• 1:00:47
  Speaker 3: had a good solution that was just a supplement that
• 1:00:49
  Speaker 3: was just to work out a little bit harder, that
• 1:00:51
  Speaker 3: would just give them a little bit. But in our
• 1:00:54
  Speaker 3: nation specifically, it's so distorted, Paul, that it barely touches it.
• 1:01:00
  Speaker 3: That's a bigger question, right, like why are we allowing
• 1:01:02
  Speaker 3: this to get this dysfunction? That's a whole bit.
• 1:01:04
  Speaker 4: Once you get down the rabbit holed or or actually
• 1:01:08
  Speaker 4: it's a bit more like a whirlpool than the slide,
• 1:01:11
  Speaker 4: right because the lower you get, the stronger the down
• 1:01:14
  Speaker 4: would pool actually becomes, right.
• 1:01:16
  Speaker 3: Because the biology affects the mentality, and the mentality then
• 1:01:19
  Speaker 3: makest your sanitary and changes your habits, and then that
• 1:01:22
  Speaker 3: affects the biology.
• 1:01:23
  Speaker 4: Yeah, absolutely, very complicated picture. But but but bond that
• 1:01:27
  Speaker 4: that a lot of people will be going, oh shit,
• 1:01:29
  Speaker 4: this makes a lot of sense. So so typically, so look,
• 1:01:33
  Speaker 4: I'm in my fifties, so I imagine, let's just say
• 1:01:37
  Speaker 4: I came to you, but but I'm I'm I'm like
• 1:01:39
  Speaker 4: your typical patient.
• 1:01:40
  Speaker 1: I'm feeling shit.
• 1:01:42
  Speaker 4: I'm overweir, I've got low sex drive and maybe insulin resistant,
• 1:01:45
  Speaker 4: you know, and just like I'm a mid going through
• 1:01:48
  Speaker 4: a mid life crisis. Typically, what would what would a
• 1:01:53
  Speaker 4: an intergod intervention look like? Would you start with just testosterone?
• 1:01:58
  Speaker 4: Would there be DJ, would it be growth hormone? What
• 1:02:02
  Speaker 4: what sort of leavers are you using?
• 1:02:04
  Speaker 1: I mean what order.
• 1:02:08
  Speaker 3: The vast majority of patients when they come to me, uh,
• 1:02:12
  Speaker 3: if they're male, I'm giving you know. Of course I'm
• 1:02:14
  Speaker 3: gonna look at the labs to confirm what their symptoms
• 1:02:17
  Speaker 3: are telling me. But it's almost always yeah, I start
• 1:02:23
  Speaker 3: them on testosterone, and I don't do I. I you know,
• 1:02:28
  Speaker 3: old science was you start one thing at a time,
• 1:02:31
  Speaker 3: you let that work, and then you add another one
• 1:02:33
  Speaker 3: because if you have a symptom or side of it.
• 1:02:35
  Speaker 3: But because of the severity and how many things we
• 1:02:39
  Speaker 3: have to add, if we do that, it's gonna take
• 1:02:41
  Speaker 3: us years to get yeah, right, And so it's just
• 1:02:45
  Speaker 3: that this is for for the sake of time, which
• 1:02:48
  Speaker 3: is arguably the most important thing in people's life. Right.
• 1:02:51
  Speaker 3: You don't have a limited amount of time on this earth.
• 1:02:54
  Speaker 3: We try to get you as optimized as possible the quickest.
• 1:02:58
  Speaker 3: And so this involves testoster This involves replacing d h
• 1:03:03
  Speaker 3: g A, which is always dysfunctional. It replaces thyroid. You know,
• 1:03:07
  Speaker 3: thyroid is so dysfunctional, Paul, and I was on testosterol
• 1:03:11
  Speaker 3: for five years before I started to get really educated
• 1:03:15
  Speaker 3: and realize it's global. And so then when I replaced
• 1:03:18
  Speaker 3: my thyroid, it changed, It changed everything. My energy, I
• 1:03:22
  Speaker 3: was cold all the time, everything switched around. And so
• 1:03:26
  Speaker 3: we replaced thyroid. So what are you giving them for first?
• 1:03:31
  Speaker 3: So first thyroid, you know, we give either some form
• 1:03:36
  Speaker 3: of desiccated thyroid, things like armor thyroid, which is trade
• 1:03:40
  Speaker 3: in this country. Uh, synthetic like synthroid or leve a.
• 1:03:44
  Speaker 3: Thyroxine is is the worst thing you can give a
• 1:03:47
  Speaker 3: patient because that is only replacing T four, which is
• 1:03:51
  Speaker 3: one form of thyroid, and T four converts to T
• 1:03:54
  Speaker 3: three naturally in the blood. But what you give synthetic,
• 1:03:57
  Speaker 3: it doesn't convert well, and so now you're blocking that component.
• 1:04:01
  Speaker 3: And so the synthetic almost acts like an endocondesruption. And
• 1:04:04
  Speaker 3: so patients who are on synthroid often don't feel better.
• 1:04:07
  Speaker 3: And then they get their labs and the doctor says,
• 1:04:09
  Speaker 3: you're fantastic, you're on the synthroid. YEA. But I transfer
• 1:04:12
  Speaker 3: all those patients over to desiccated and that's what we
• 1:04:15
  Speaker 3: used to use fifty years ago before the synthetic version
• 1:04:17
  Speaker 3: was formed, and people did fantastic. And so we give
• 1:04:21
  Speaker 3: we give desiccated thyroid testosterone DHA, and then I make
• 1:04:26
  Speaker 3: sure that their vitamin D is adequately treated. In this country,
• 1:04:29
  Speaker 3: nobody's vitamin D is good. You know, they block it
• 1:04:32
  Speaker 3: with some block if they go outside. Most people aren't
• 1:04:34
  Speaker 3: even going outside.
• 1:04:35
  Speaker 1: I know, it's like and in this country.
• 1:04:38
  Speaker 4: So I come from a country where the sun is
• 1:04:41
  Speaker 4: a mythical creature, right, and so as soon as the
• 1:04:46
  Speaker 4: summer's art, everybody's there. And now I live in Australia
• 1:04:49
  Speaker 4: where it's something to be feared. In Australia, there is
• 1:04:52
  Speaker 4: levels of vitamin D deficiency and insufficiency equivalent to Scandinavia,
• 1:04:58
  Speaker 4: Scotland and Ireland.
• 1:04:59
  Speaker 1: Right, it's crazy.
• 1:05:01
  Speaker 4: So and most people don't realize if you've got little
• 1:05:03
  Speaker 4: vitamin D, you increase your risk of almost every other consident,
• 1:05:07
  Speaker 4: skin cancer, you increase your risk of depression. I mean regularly,
• 1:05:09
  Speaker 4: it's two thousands of your twenty right, yeah.
• 1:05:14
  Speaker 3: System right. They showed during COVID's debacle, the one thing
• 1:05:17
  Speaker 3: useful that came out of this thing was we've shown
• 1:05:20
  Speaker 3: that people who were supplemented with vitamin D eighty or
• 1:05:23
  Speaker 3: above their risk of COVID was decreased and the instance
• 1:05:27
  Speaker 3: of severity was decreased. And so we know it's crucial.
• 1:05:31
  Speaker 3: The sun is not our enemy. We've made it the
• 1:05:33
  Speaker 3: enemy side. Yeah, and then we took that and we
• 1:05:36
  Speaker 3: put chemicals all over us to blocket that are actually
• 1:05:39
  Speaker 3: you know, increasing our risk for cancer sadly.
• 1:05:42
  Speaker 1: And a lot of that.
• 1:05:43
  Speaker 4: In recent study in Australia show did it. It was
• 1:05:45
  Speaker 4: more than fifty percent of the sunscreens find were ineffective
• 1:05:49
  Speaker 4: at doing their job and just as you said, their
• 1:05:51
  Speaker 4: chemical shit storms as well. But anyway, that so that
• 1:05:55
  Speaker 4: then goes into the mix. I'll say, cheeses, get your
• 1:05:58
  Speaker 4: vitomin day levels. Checked and and look for optimal. I
• 1:06:02
  Speaker 4: think we've got different measurement levels in the States, and
• 1:06:06
  Speaker 4: here we talk about nanimals per liter and and it's
• 1:06:09
  Speaker 4: one hundred hundred and fifty.
• 1:06:10
  Speaker 1: I think it's about sixty, is it? What what do
• 1:06:13
  Speaker 1: you guys use for? Is it milograms per uh? What's
• 1:06:17
  Speaker 1: we get? Well?
• 1:06:18
  Speaker 3: Yeah, it's billigrams. But I but I I just tell
• 1:06:21
  Speaker 3: patients to keep it simple because most of the studies
• 1:06:23
  Speaker 3: show this. And and when you international units or micrograms
• 1:06:28
  Speaker 3: for dose, yeah, take ten thousand a day in our nation.
• 1:06:31
  Speaker 3: In our nation, if you take ten thousand international units
• 1:06:33
  Speaker 3: a day, you'll get your levels two above where they
• 1:06:37
  Speaker 3: should be and you're going to have a huge impact
• 1:06:39
  Speaker 3: in your immune system and all your functions.
• 1:06:41
  Speaker 4: Because yeah, yeah, yeah, I think I totally agree. So
• 1:06:44
  Speaker 4: so basically, you would be looking at a protocol for
• 1:06:48
  Speaker 4: the and I know what.
• 1:06:49
  Speaker 1: It varies for individual.
• 1:06:51
  Speaker 4: But when you're looking at testofsny DSA, you're looking up
• 1:06:54
  Speaker 4: tomiz and vitamin D and and.
• 1:06:56
  Speaker 1: Probably testicated thyroid.
• 1:07:00
  Speaker 4: So is gross hormone just that they purvey of of
• 1:07:05
  Speaker 4: athletes to your one to cheat or is does growths
• 1:07:09
  Speaker 4: hormone have a role in how some whale being No.
• 1:07:13
  Speaker 3: They're doing, they're doing. They did a small study, not
• 1:07:17
  Speaker 3: a lot of entries into it, but showing amazing promising
• 1:07:21
  Speaker 3: effects of how important growth warman is. But now they're
• 1:07:25
  Speaker 3: doing on a grander scale. The problem with growth hormone
• 1:07:27
  Speaker 3: is that in this country it is highly restricted. Like
• 1:07:31
  Speaker 3: so when you talk about giving testosterone, our country's labeled
• 1:07:35
  Speaker 3: testosterone in the same category as heroin and narcotic. Right,
• 1:07:39
  Speaker 3: it's the most highly restricted thing you can prescribe, right,
• 1:07:44
  Speaker 3: growth hormone. Testosterone. Growth hormone is even more difficult to
• 1:07:49
  Speaker 3: get out. Really, it's even more difficult, and if you
• 1:07:51
  Speaker 3: do get it, the price precludes it. We're talking if
• 1:07:54
  Speaker 3: you wanted to do a yearly microdosing regimen of growth
• 1:07:58
  Speaker 3: warmer for most patients somewhere in the range of twenty
• 1:08:01
  Speaker 3: to thirty thousand dollars. So for most pases, sadly this
• 1:08:05
  Speaker 3: becomes a non issue because it can't afford it. But
• 1:08:08
  Speaker 3: growth hormone is massive and it's so important as we
• 1:08:11
  Speaker 3: get older. Right, there's a lot of peptides that are
• 1:08:14
  Speaker 3: showing excellent effects for helping us squeeze out some extra
• 1:08:19
  Speaker 3: of our own capacity and those do work fantastic. I
• 1:08:22
  Speaker 3: used them personally, and they work for a certain period
• 1:08:25
  Speaker 3: of time and then they kind of lose their effect
• 1:08:29
  Speaker 3: and growth homer needs to be added at a microdose
• 1:08:32
  Speaker 3: to get that benefit. And that's usually in the fifties
• 1:08:36
  Speaker 3: where you see that that growth home and analogs. It's
• 1:08:38
  Speaker 3: secretagogus peptides don't work as effective anymore. But for elderly,
• 1:08:42
  Speaker 3: if bu of my way, all the elderly would have
• 1:08:44
  Speaker 3: access to growth homone. It helps with bone production, it
• 1:08:47
  Speaker 3: helps with Alzheimer's and muscle tone. Right, nothing more important
• 1:08:50
  Speaker 3: than muscle tone as we age for mortality, and we
• 1:08:55
  Speaker 3: need growth home and desperately, So if I had access
• 1:08:57
  Speaker 3: to it, it would absolutely be right out the gate.
• 1:09:00
  Speaker 4: But it's very much, but it's right. Okay, that's interesting. Now,
• 1:09:04
  Speaker 4: that was a nice segue because I did want to
• 1:09:07
  Speaker 4: transition to talk about peptides, and I was going to
• 1:09:09
  Speaker 4: talk about some of the because there's a there's a shitload.
• 1:09:13
  Speaker 1: Of of peptides that are out there, whether it's the
• 1:09:16
  Speaker 1: moral and and promo moral and c JC, all of
• 1:09:20
  Speaker 1: these things, but but just the peptides more globally.
• 1:09:24
  Speaker 4: Now I know that the legislation is changing or I
• 1:09:28
  Speaker 4: don't know if it just has changed now in the
• 1:09:30
  Speaker 4: United States where there's nice some of the peptides coming.
• 1:09:34
  Speaker 1: On that you will be able to prescribe, Is am
• 1:09:37
  Speaker 1: I correct in that?
• 1:09:39
  Speaker 3: This is the this is the union. This is the
• 1:09:40
  Speaker 3: funny thing about the peptides. Prior to g LP ones,
• 1:09:45
  Speaker 3: peptides were in a category that listed them as we're
• 1:09:50
  Speaker 3: not sure of their safety. However, we livered to the
• 1:09:53
  Speaker 3: discretion of the physician to decide with the patient what
• 1:09:58
  Speaker 3: they want to do, and they were readily available. GLP
• 1:10:02
  Speaker 3: ones came around, and then GLP two's really to his
• 1:10:05
  Speaker 3: appetite these types of drugs, And then which are peptides
• 1:10:10
  Speaker 3: right their own by particular pharmaceutical companies, And then the
• 1:10:16
  Speaker 3: restrictions started coming in, right, no, no, no, you can't
• 1:10:19
  Speaker 3: compound farmies cannot do this.
• 1:10:20
  Speaker 4: And they didn't just come in and regularly now and
• 1:10:22
  Speaker 4: if they says driven by the pharmaceutical company.
• 1:10:24
  Speaker 3: Wow, and so they so, then they changed the categorization.
• 1:10:28
  Speaker 3: Then peptides no longer things like BPC. I don't know
• 1:10:32
  Speaker 3: if you heard these things, but many, almost all the
• 1:10:34
  Speaker 3: lists of peptides overnight switched from at the discretion of
• 1:10:38
  Speaker 3: the physician with conference with the patient to these are
• 1:10:43
  Speaker 3: not we don't know the safety and because of that,
• 1:10:46
  Speaker 3: you can't have access to them until we study them. Well,
• 1:10:49
  Speaker 3: you know, we know in this nation that it costs
• 1:10:51
  Speaker 3: tens of millions of dollars to study everything that you
• 1:10:53
  Speaker 3: want to study. And the reality is peptides have been
• 1:10:56
  Speaker 3: around in Europe and in Russia and studied for fifty years.
• 1:11:01
  Speaker 3: Uh and it was not a problem for us to
• 1:11:02
  Speaker 3: get access to it until those those jumpy ones. Now
• 1:11:07
  Speaker 3: there's talk in the legislator to putting it back to
• 1:11:10
  Speaker 3: where it was, so not not really giving us access,
• 1:11:14
  Speaker 3: giving it back to where we have the access that
• 1:11:16
  Speaker 3: they have recently taken from us. So we can't prescribe it.
• 1:11:19
  Speaker 3: So as a physician, I can't prescribe. I can prescribe
• 1:11:23
  Speaker 3: certain things that the FD eight decides is on the list.
• 1:11:26
  Speaker 3: Most of the peptides they want in modalities that are
• 1:11:29
  Speaker 3: not useful yet. So they'll give you'll give you a
• 1:11:31
  Speaker 3: certain peptide in an oral form but it's not effective,
• 1:11:34
  Speaker 3: or they'll give it in a nasal summer form or
• 1:11:36
  Speaker 3: good nasal, but many aren't and so it takes them
• 1:11:39
  Speaker 3: off the list.
• 1:11:40
  Speaker 4: Yeah, and are you Are you excited about the potential
• 1:11:46
  Speaker 4: of peptides as longevity medicine A two years.
• 1:11:52
  Speaker 3: I've used peptides personally for years. I think they're amazing.
• 1:11:55
  Speaker 3: I think they have so much potential. I tell patients,
• 1:12:01
  Speaker 3: at least in this country, you know, you got to
• 1:12:04
  Speaker 3: have your hormones optimal. You have to make sure that
• 1:12:06
  Speaker 3: they're good. You could use peptides at any time. However,
• 1:12:10
  Speaker 3: when your body's not running optimally, the peptides work far
• 1:12:14
  Speaker 3: less effectively and they become very costly because these things
• 1:12:17
  Speaker 3: can be expensive. So I always tell patients make sure
• 1:12:19
  Speaker 3: you're optimally normally balanced, and then you can use these peptides.
• 1:12:22
  Speaker 3: But yes, this is exciting stuff. This is preventative stuff, Paul, Right,
• 1:12:27
  Speaker 3: this is hey, I could take certain things to help
• 1:12:30
  Speaker 3: prevent things, or if I do get sick, I could
• 1:12:32
  Speaker 3: take a protein based product that doesn't have the side
• 1:12:35
  Speaker 3: effect profile of antibiotic or anti virals that will help
• 1:12:39
  Speaker 3: me fight off things right more naturally. Really, no, it's
• 1:12:44
  Speaker 3: absolutely exciting. This is what you would hope the future
• 1:12:47
  Speaker 3: will be. But I'm not naive to medicine. I've been
• 1:12:50
  Speaker 3: in for twenty years. There's so much financial gain in
• 1:12:53
  Speaker 3: this nation for those who are deciding those who are
• 1:12:57
  Speaker 3: deciding right, not the physicians per se, but boards and
• 1:13:00
  Speaker 3: the f d A and the first pharmaceutical companies and
• 1:13:03
  Speaker 3: the legislator. These people are making the rules and they're
• 1:13:07
  Speaker 3: not in the best interest of of of patients over
• 1:13:10
  Speaker 3: profit right, profit comes first.
• 1:13:12
  Speaker 4: Yeah, no, look absolutely, it is a bit of a
• 1:13:16
  Speaker 4: sad state of as far as but but you know,
• 1:13:18
  Speaker 4: hopefully patient interest will will win out in the end.
• 1:13:22
  Speaker 4: And Mike, this is this has been really awesome, a
• 1:13:25
  Speaker 4: really good education on the the importance of hormones, but
• 1:13:30
  Speaker 4: also giving people as a steer on the on the
• 1:13:34
  Speaker 4: sense of where we're at from a research perspective and
• 1:13:36
  Speaker 4: the and the importance of the different things. So so
• 1:13:38
  Speaker 4: me thank you and this has been particularly awesome and fun.
• 1:13:42
  Speaker 4: Were where people go to find out more about you
• 1:13:47
  Speaker 4: and your services.
• 1:13:49
  Speaker 3: Sure, we go to w w W optimize, MD dot
• 1:13:53
  Speaker 3: health and then you can chat with me on there.
• 1:13:56
  Speaker 3: I have I have some AI interaction that I am.
• 1:13:59
  Speaker 3: I jump in. You can ask all kinds of questions
• 1:14:02
  Speaker 3: and we'll give you most of the answers that we
• 1:14:03
  Speaker 3: talked about here. Uh, and then you can you know
• 1:14:06
  Speaker 3: if you're looking for treatment, we can we can go there. Cool.
• 1:14:11
  Speaker 4: So if you're getting optable and you live in the
• 1:14:13
  Speaker 4: state it state, do you do distant stuff or the
• 1:14:16
  Speaker 4: people have to come and see your fist to fears, No,
• 1:14:18
  Speaker 4: I do tell it.
• 1:14:19
  Speaker 3: I mean, I have licenses in forty something states. But wow,
• 1:14:24
  Speaker 3: you need a license in every stea it that you
• 1:14:25
  Speaker 3: do practice? You know, you don't. You know, this is
• 1:14:28
  Speaker 3: the funny thing. You don't. Initially, during prior to COVID,
• 1:14:31
  Speaker 3: you just needed one license. I'm an MD, you know,
• 1:14:35
  Speaker 3: and you got your board certification and it worked state
• 1:14:38
  Speaker 3: to state. Then they opened up telemedicine, UH, and then
• 1:14:42
  Speaker 3: each state started to dictate what rules they wanted. And
• 1:14:46
  Speaker 3: then over time, UH, certain states will say, hey, you
• 1:14:49
  Speaker 3: can't see our patient unless you physically see them once
• 1:14:52
  Speaker 3: a year, or you have a state license in our style.
• 1:14:56
  Speaker 3: So to make it easier for patients, stream difficulty to
• 1:15:00
  Speaker 3: have licenses in all those states down the paperwork is
• 1:15:04
  Speaker 3: just astounding. But then I can then I could treat
• 1:15:07
  Speaker 3: more patience. There's not an issue, you know, if they're
• 1:15:10
  Speaker 3: in one of those states. So I say the majority
• 1:15:12
  Speaker 3: of my patients are telemedicine, you know, we do like this,
• 1:15:14
  Speaker 3: interview them on the screen, we get their labs, we
• 1:15:16
  Speaker 3: talk about their symptoms, and then we come up with
• 1:15:19
  Speaker 3: a plan. And it works great because I get to
• 1:15:21
  Speaker 3: see I can I could see them more often. It's
• 1:15:23
  Speaker 3: more convenient for them, and yeah, it works out great.
• 1:15:25
  Speaker 3: Actually yeah cool, yeah, that's awesome.
• 1:15:27
  Speaker 4: All right, excellent, So optimize AMD dot health is the
• 1:15:32
  Speaker 4: place to go.
• 1:15:33
  Speaker 3: Mike.
• 1:15:33
  Speaker 1: This has been bloody awesome.
• 1:15:35
  Speaker 4: And thank you for all your work and for transitioning
• 1:15:39
  Speaker 4: from the sick cur and system into the healthcare system.
• 1:15:43
  Speaker 3: Thank you, Paul. Thanks for doing what you do. Man.
• 1:15:45
  Speaker 3: We need people, you know, like you spread the word
• 1:15:47
  Speaker 3: on all these topics. It's important.
• 1:15:48
  Speaker 1: Yeah, yeah, cool man, thank you.
• 1:15:51
  Speaker 3: Okay, cheers,