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The Yak Mutation That Could Help Repair the Brain (EP 56)
What can a yak living thousands of meters above sea level teach us about repairing the human brain?
In Episode 56 of From First Principles, Lester Nare and Krishna Choudhary break down a new Neuron paper that traces an evolutionary adaptation found in high-altitude animals to a previously hidden pathway involved in building and repairing myelin.
Summary
What myelin actually does and why losing it disrupts neural communication
How multiple sclerosis damages myelin and why the brain’s natural repair process eventually fails
Why oligodendrocyte precursor cells can remain present in damaged…
The skinny
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