Latest / Intellectual Medicine / One Habit That Cuts Prostate Cancer Death Risk by 61%
Transcript
- 0:00A lot of longevity studies have correlated grip strength with a
- 0:04longer lifespan power. Other studies have correlated
- 0:09muscle mass. More muscle, more longevity.
- 0:14I like those studies in part because they reinforce my own
- 0:17bias. I like lifting weights.
- 0:20I do it even though my joints are arthritic.
- 0:22I do it even though it can hurt sometimes painful.
- 0:26So stay active, stay vital, right?
- 0:28It's all part of what we're talking about, man.
- 0:30It's fighting cancer like a man. What if I told you that there's
- 0:35something you can do that doesn't cost you any money, but
- 0:39it can reduce your risk of dying from prostate cancer if you have
- 0:43the disease by over 60%? I'm talking about a specific
- 0:49form, duration and intensity of exercise, which I'll share with
- 0:53you. These details matter.
- 0:55Thank you for tuning into my podcast.
- 0:57A voice of clarity and logic and an ocean of chaos.
- 1:03The more you read about prostate cancer, the more of a fuddling
- 1:07it becomes. Now exercise in particular is
- 1:10hard to assess. It is hard to create a study
- 1:14looking at that variable. A lot of men who exercise also
- 1:19do other things to maintain their good health and not all
- 1:23exercise is the same. The dose, duration, intensity,
- 1:26these things all matter. So we've got to get to the
- 1:30amount that you need to do or that I recommend that you do.
- 1:34I don't like the word need, right?
- 1:35When it comes to your lifestyle. Look, you can choose to sit on
- 1:39the couch. That's totally cool.
- 1:42You may not have progression of your cancer.
- 1:44Anyhow. This is the realm in which we
- 1:46live. But by virtue of your tuning
- 1:48into my podcast, I'm going to gather we're kind of like
- 1:52minded, right? My definition of good health,
- 1:56vibrant vitality, abundant energy, a clear brain, muscles
- 2:02that work. And this doesn't fade.
- 2:05It should never fade. There's nothing about human
- 2:09beings that biologically requires us to wither and to age
- 2:14before we die. We can and we should aspire to
- 2:19maintain youthful energy throughout the entire span of
- 2:22our life. And that's not just hyperbole,
- 2:24man. It's not just a pipe dream.
- 2:27It's real hell. I'm living it.
- 2:29Many of my patients are living it.
- 2:31You're living it. So do not let any presumption of
- 2:36decay lull you into complacency. Now a couple of other headlines
- 2:41as we talk about exercise, what to do and how much to do in the
- 2:46United Kingdom. Recently, after much study, they
- 2:51decided not to do screening for prostate cancer specifically.
- 2:56They're not recommending nor are they paying for the prostate
- 3:00specific antigen, the PSA test, the Holy Grail of prostate
- 3:04cancer assessment. Many people think this is a
- 3:08horrible decision. I understand it.
- 3:11I don't agree with it. And here's the split.
- 3:15It's not the PSA that is really the problem, it's the way it's
- 3:19abused. Manipulated the way it is
- 3:23misrepresented to take totally healthy men and convince them
- 3:29that they need to RIP out their prostate or do some other God
- 3:33awful act of masculine violation otherwise they're going to die.
- 3:39And I've heard men share the story.
- 3:41Guys don't believe it. It is hyperbole.
- 3:46It is driven to maintain the status quo.
- 3:50We should not be doing prostate biopsies anymore.
- 3:53That time has passed. It's dead.
- 3:56It just doesn't know it yet. It may take us 50 years to get
- 4:00to that point. The inertia from the medical
- 4:04insurance, not really insurance so much, but the medical
- 4:07pharmaceutical complex is intense.
- 4:11A lot of a lot of money being made.
- 4:13There's a new drug coming to market, I'm sure there is, to
- 4:16treat prostate cancer by other manipulative methods.
- 4:20You don't treat prostate cancer unless you convince men that
- 4:23they got it with APSA and a biopsy.
- 4:26So don't do it. How about doing an MRI?
- 4:30Yes, combined with PSA periodically you can tell the
- 4:34trajectory. Now, what's going on in England
- 4:36and what should you do besides the exercise?
- 4:39I'm about to give you the details about yes to the PSA but
- 4:43do not see, I almost feel I almost feel that the urologist
- 4:50is not the right specialist to help interpret that result.
- 4:54Why they want a biopsy you, they're busy.
- 4:58They don't have time to talk to you like I am right now.
- 5:01Reflecting risk benefits stats, the Protect T trial, the PIVOT
- 5:06trial showing no benefit in survival despite prostatectomy
- 5:12should color our thinking. They don't have time, they don't
- 5:16have the interest. A biopsy is highly reimbursed.
- 5:21A biopsy gives him a degree of insulation against malpractice.
- 5:26After all, if you see the urologist and he can do a biopsy
- 5:31and chooses not to because he's a good guy and a woman and
- 5:35thoughtful about it, somebody later could blame them for
- 5:38delayed diagnosis. It gets complicated.
- 5:40Men, you, you are in charge. So what to do?
- 5:45Let's reflect on the role of exercise in preventing prostate
- 5:49cancer. It's unknown.
- 5:52What we know about exercise is that the right dose does
- 5:56stimulate immunologic enhancement.
- 5:59The biomarkers showing immune function improve, but there is
- 6:04something called EU shaped curve.
- 6:05That's AU. It's AU shaped curve.
- 6:08Too much exercise can be damaging.
- 6:11In fact, one study looking at heart disease, atrial
- 6:14fibrillation in particular, noted that couch potatoes and
- 6:19high intensity exercises have the same higher rate of atrial
- 6:24fibrillation and irregular heartbeat than guys and gals who
- 6:28did something more modest. What about the immune system?
- 6:32I know, you know, we know that your immune system fights cancer
- 6:37every day. Anything that you can do that
- 6:41amplifies immune function is to your benefit.
- 6:44Exercise does that unless it's too much.
- 6:49The high intensity exercise. Now listen, you're not doing
- 6:53that. I'm talking folks that do
- 6:56marathons that compete in 10 KS. Now we have to draw a
- 7:01distinction between health and athleticism.
- 7:06A VO2 Max, which some doctors promote as a correlant of
- 7:11longevity. It isn't.
- 7:14It's a measure of athletic capacity.
- 7:17A great runner has a high VO2 Max.
- 7:20They can process oxygen really, really well.
- 7:23They ain't going to live longer because of it.
- 7:26That high intensity exercise, that marathon or that Olympic
- 7:30athlete in the time after their intense exertion, they're
- 7:35immunologically vulnerable. So exercise, you don't need to
- 7:38worry about that to do that kind of high intensity exercise.
- 7:42I don't know, maybe I'm projecting here, right?
- 7:44But I don't like to sweat or breathe heavy when I exercise.
- 7:48I like to do just enough to keep me from not dying.
- 7:52So here's the magic number. It's three hours per week of
- 7:58vigorous walking. That was the threshold that
- 8:02correlated with the best outcomes. 2 separate studies, by
- 8:05the way, actually three of them. Multiple studies supporting this
- 8:10concept. 3 hours. In one study there was a 57%
- 8:16reduction in the rate of progression of cancer.
- 8:19Slowed it down 57%. Now that's not 3 hours and 1
- 8:23chunk. Bear in mind it's three hours
- 8:26over the course of your week. Let me do the math here. 30
- 8:31minutes, six days a week you take Sunday off.
- 8:35You can do this without having to sweat heavy or breathe heavy.
- 8:39It counts. There is also in another study,
- 8:43a 61% reduction in the death rate from prostate cancer when
- 8:48you hit the three hour mark. Now, does that mean that 2 1/2
- 8:53hours won't work? It does not.
- 8:56The important detail for your life is to make it fit your
- 9:00life. If three hours is motivational,
- 9:03awesome, go do it. Here's another thing I like
- 9:06about this doesn't cost money. Another thing I like about this.
- 9:12We talk about collateral benefit a lot, which means the side
- 9:16effect of treatments that have enhancing value to your health
- 9:19and longevity. Walking is one of them.
- 9:23There was also a decrease in all 'cause mortality, right?
- 9:27What are you, most of us going to die from?
- 9:29Men? Heart disease?
- 9:31Can The Walking help prevent it? It appears so.
- 9:34It appears so. How about strength training?
- 9:38How about pump and iron? There's less known about lifting
- 9:43weights and resistance strength training.
- 9:46The studies are really hard to do, but here are some details
- 9:50that showed correlation of benefit.
- 9:53A lot of longevity studies have correlated grip strength with a
- 9:57longer lifespan power. Other studies have correlated
- 10:03muscle mass. More muscle, more longevity.
- 10:07I like those studies in Park cause 8 reinforce my own bias.
- 10:12I like lifting weights. I do it even though my joints
- 10:15are arthritic. I do it even though it can hurt
- 10:18sometimes painful. But I like the result.
- 10:22And so should you because there's an important study now
- 10:24looking at fat, visceral fat, prostate cancer.
- 10:29A a comparable but separate thing is controlling percent
- 10:34body fat. Men who gained five points on
- 10:39their body mass index had an increased rate of cancer death
- 10:43from prostate cancer. Men who had an increase of body
- 10:47fat after the diagnosis had an increased rate of death from
- 10:52prostate cancer. But it's a little nuanced.
- 10:55It's the visceral fat that matters the most.
- 10:57That's that fat in the, in the abdomen.
- 11:01You know, the big sick belly, that's the fat you want to go
- 11:04after. Now be careful.
- 11:06You don't want to just lose weight.
- 11:09You must target fat. So I'll be talking about that.
- 11:12It'll be detailed in my book, but we'll we'll highlight this
- 11:15during podcast as well. I can tell you the quick
- 11:19summary, do not fast. Intermittent fasting shrinks
- 11:23muscle. Make sure you have at least
- 11:27three meals per day. There's no such thing as a
- 11:30healthy snack. Everything's a meal should be
- 11:33protein centered. Those are the foundational
- 11:36elements of keeping muscle on your body in addition to the
- 11:39resistance training. What about the correlation?
- 11:43There's a correlation between higher muscle mass and less
- 11:48consequence from prostate cancer.
- 11:50Now this dovetails into the role of testosterone itself.
- 11:56To keep your muscles, you must have enough testosterone.
- 12:01To grow the muscle, you must to some form of resistance
- 12:04training. And no, walking doesn't count
- 12:07for growing muscle. A lot of scrawny walkers out
- 12:10there. You got to do more, man.
- 12:12I'm sorry. You got to do more.
- 12:13Twice a week at least, right? Twice a week, some strength
- 12:16training. And the third thing, you got to
- 12:19have protein. It is overlooked, undervalued,
- 12:22got to have the protein. So you put those three things
- 12:24together. What about testosterone?
- 12:27So there's growing evidence that testosterone can be used safely
- 12:34and effectively in the setting of men with prostate cancer or
- 12:40with an elevated PSA and an abnormal prostate MRI.
- 12:45One study was looking at not men who had cancer, but rather men
- 12:50on testosterone therapy and tracking them for the risk of
- 12:54cancer progression. They actually found that men on
- 12:58testosterone had a lower incidence, a lower rate of
- 13:02prostate cancer than men who are not on it now.
- 13:06This is starting to make sense, isn't it?
- 13:09We've known for a long time that having a low testosterone level
- 13:14increases your risk of developing prostate cancer.
- 13:18What's less known is whether or not replacing testosterone will
- 13:22help prevent that from happening.
- 13:24The evidence is starting to point that it may, which takes
- 13:28us back another step. Why do we get prostate cancer
- 13:33when our testosterone levels are declining versus when they're
- 13:37high when we're younger? And why should we then target
- 13:42lowering testosterone as a means of treating prostate cancer?
- 13:47We shouldn't percent body fat control it.
- 13:51Exercise incorporated testosterone, properly
- 13:56administered men, it's your friend.
- 13:59Now, there are some settings in which this should not be done.
- 14:02If you have prostate cancer that is in the bone, you've got to
- 14:06control the bone 1st. And no, do not do this with your
- 14:10online testosterone gumball machine prescribers, your unique
- 14:15cohort. We're coming for you.
- 14:18The prostate cancer community is available and developing.
- 14:23My course on the Pederuti protocol will be out in April.
- 14:27We'll be training other clinicians and how to do this
- 14:30protocol. In the meantime, you're better
- 14:34off biting time. Prostate cancer moves slowly, so
- 14:38get out there. Keep walking. 10,000 steps?
- 14:41Meh, not that important. Three hours a week?
- 14:45That seems to have value, so go ahead and put it to work for
- 14:48you. And no, it doesn't matter what
- 14:51the weather is. I know I'm down here in Fort
- 14:53Lauderdale. Good for me, right?
- 14:54But how about if you're up there in Chicago right now, right?
- 14:58Get out there and walk. If you get on a treadmill, it
- 15:01doesn't matter if you're outside or inside.
- 15:04I kind of like outside better. But if I'm in Chicago, I think
- 15:08I'm looking for a treadmill right here.
- 15:10You are walking to protect your health.
- 15:12You're going to slip and fall and break your hip.
- 15:14That's not cool. By the way, the 30 minutes of
- 15:18walking. Although this study didn't look
- 15:19at this, I believe you could extrapolate into other
- 15:23cardiovascular activity. How about a Zumba class check?
- 15:28How about bike riding check. No, bike riding does not damage
- 15:33your prostate. Now, if you go on a long bike
- 15:36ride and get your PSA done the next day, you're going to see a
- 15:38bump, but it doesn't mean it's increasing cancer risk.
- 15:43So stay active, stay vital, Right?
- 15:45It's all part of what we're talking about, men.
- 15:47It's fighting cancer like a man fighting cancer head on
- 15:51vigorously, not succumbing to fear, anxiety and false markers.
- 15:57Like, oh, my God, your PSA needs a biopsy.
- 16:01All right, well, thanks for tuning in with me, guys.
- 16:04Talk to you next time. Bye.