Solving the Liver Organ Shortage - Strategies and Innovations

Trenches in Transplant Surgery · Jun 17, 2025 · 15m

• Research suggests increasing public awareness and opt-out donation systems can boost liver donations, though effectiveness varies by region.

• It seems likely that using extended criteria donors and split liver techniques can expand the donor pool, but outcomes may differ.

• The evidence leans toward machine perfusion and bioengineered livers as promising innovations, though they are still experimental.

• Policy changes, like optimizing allocation, may help, but face ethical debates; living-donor transplants show potential with support.