Latest / The Shivan Show with Shivan Sarna / Recurrent UTIs? Check Your Morning pH | Ruth Kriz Part 2
Transcript
- 0:00If you missed part one, go back and listen.
- 0:02We covered why interstitial cystitis may be a chronic infection actually embedded in the bladder wall, why cultures come back clean and antibiotics stop working, what proper testing finds that a culture can't,
- 0:15and how treatment should be sequenced.
- 0:18And in this part, we're going to discuss ammonia, urine pH, and the root causes underneath recurring infections.
- 0:26It's not what most doctors talk about.
- 0:29This is new and different information that we're trying to get globally dispersed around the world so more women can feel better.
- 0:37Plus, did you know you have to treat your partner?
- 0:40Bacterial vaginosis and the vaginal pH are also covered, and how the timing of your antibiotics change how well they work.
- 0:47We had a lady in Texas whose urologist wanted to remove her bladder.
- 0:51It's because of the high ammonia, damaging the bladder wall, setting you up for infections.
- 0:57So leaving ammonia sitting in your bladder all night long is a really bad idea.
- 1:02Let's talk a little bit about ammonia because I'm becoming more and more convinced that that is a huge player
- 1:13in why people have some of these infections.
- 1:17This is on the provider section for practitioners, but it shows many of the bacteria that are coming back on the microgen test, often missed by the cultures, but it also tells you at what pH that bacteria flourishes at.
- 1:39which type of biofilm that bacteria makes, and whether or not it makes ammonia.
- 1:48And some bacteria make something called urease that uncouples ammonia from urea or urine and dumps it back into the bladder.
- 1:58Now the problem... Scroll up, Ruth, so everyone can see the rest of this.
- 2:03If you're a patient, can they... Yeah, you guys can just like check this out.
- 2:07If you're a patient, do you have access to that section of your website?
- 2:12It's under for providers, but yes, you can get there from my website.
- 2:16So it turns out that some people genetically make too much ammonia.
- 2:25Those are called CBS mutations, cystathionine beta synthase.
- 2:31That ammonia goes over to the urea cycle.
- 2:37And during the night, it concentrates in your bladder because of antidiuretic hormone.
- 2:42That's why the color of your urine first thing in the morning is darker than during the day.
- 2:48That's why the volume is less.
- 2:51That's why your bladder doesn't fill up.
- 2:55And you have a large amount of urine in the middle of the night two or three times, unless you have mold toxins, because mold depresses ADH.
- 3:04In any event.
- 3:05You have to stop.
- 3:06What is ADH?
- 3:08Anti-diuretic hormone.
- 3:10So are you saying that if people have mold, they're not going to pee in the middle of the night?
- 3:15I'm saying they're more likely to have a full bladder with diluted urine because they don't have enough antidiuretic hormone.
- 3:23So sometimes people are getting up urinating during the night because they have an infection, but sometimes people are up urinating during the night because they have a mold toxin problem.
- 3:34Got it.
- 3:34Thank you.
- 3:37Let's get to these root causes, peeps.
- 3:40So anyway, you have the ammonia in your urine at night that's concentrating.
- 3:46What is it doing?
- 3:48That high ammonia is raising the pH of the urine, favoring the growth of many of those pathogens I just showed you.
- 3:57It's damaging the gag layer of the bladder wall.
- 4:02Gee, that's a definition of an IC patient if I ever heard of one.
- 4:06What's a gag layer?
- 4:07The layer in the bladder that takes the hit.
- 4:11When they look through the cystoscope, they see the damage, and it cracks and bleeds when you blow up the bladder with water.
- 4:17The third thing that it does is it stabilizes biofilms.
- 4:22So leaving ammonia sitting in your bladder all night long is a really bad idea.
- 4:30So what the body is supposed to do is it's supposed to make ornithine,
- 4:40Ornithine converts to citrulline.
- 4:43There are six enzymes needed to do that, and some people have genetic problems there.
- 4:50But the end result is, if you measure the urine pH first thing in the morning, and it's above 6.0, you know that your body did not do a good enough job clearing the ammonia.
- 5:07Now, ammonia can also come from bad bugs in the gut, SIBO.
- 5:13Ammonia can also come as an exotoxin of Lyme disease.
- 5:19So I always wonder, why in the Lyme community do we have such a high incidence of urinary issues and IC diagnoses?
- 5:30It's because of the high ammonia damaging the bladder wall, setting you up for infections.
- 5:35Looking for my ammonia scavenger right now.
- 5:39I'm ready.
- 5:40I need to take it like right this second.
- 5:42It's in the closet.
- 5:43So tell us about what we can do about this.
- 5:47And is it just for people who have these CBS mutations or is it a good idea for everyone during this time?
- 5:53I don't do any genetic testing because I still want to know functionally, is your body clearing the ammonia well enough or not?
- 6:01I'm sure there are many people out there with CBS mutations, and their ammonia isn't giving them any trouble, and their body is keeping up with it because they don't have other things raising the ammonia level, or they don't have any genetic problems with their urea cycle, and they're perfectly capable of getting rid of it even if it's a little higher than other people.
- 6:24But if functionally, first thing in the morning, your urine pH is above 6.0, then giving your body more ornithine, more citrulline, which are in the ammonia scavenger product, will help clear the ammonia, and that will prevent the ammonia from damaging your bladder wall, raising the pH, favoring the growth of many pathogens, and
- 6:54you know, keep you from having long-term problems with certain pathogens.
- 6:58As far as dosage goes, I want to go back to the biofilm buster.
- 7:02You like that Kirkman biofilm test.
- 7:04That's a good starting point before you test, but then once we know what you're growing,
- 7:10Then we put you on a more potent product to break down fibrin.
- 7:16That's usually one of the lumbrokinase products.
- 7:20If you're making curly, there are some supplements that break those down.
- 7:26If you make extracellular DNA, there's some supplements that break those down.
- 7:32But we don't give you all those biofilm disruptors all the time because some of them aren't good to take in the long term.
- 7:40We base it on which pathogens are showing up.
- 7:44And when you've gotten rid of those pathogens, you don't need those particular disruptors anymore.
- 7:50So it has to be very strategic.
- 7:53It's not a one-size-fits-all, throw everything at every patient and hope something works.
- 7:59That's...
- 8:01oftentimes how UTIs are being treated.
- 8:04You know, the spaghetti at the wall and see if something sticks approach.
- 8:09And so people have been given multiple antibiotics multiple times and they're still suffering because the biofilms have never been addressed and they aren't looking at what that person needs based on their genetics.
- 8:26Now, would this CBS mutation show up in a typical DNA test that we've already done?
- 8:31No?
- 8:32Maybe.
- 8:33There are 24 CBS genes.
- 8:37I think I know which two of the upregulating ones...
- 8:41end up producing extra ammonia.
- 8:43But once again, it's like you can have a genetic predisposition for diabetes, but that doesn't make you diabetic.
- 8:50So you can have a CBS mutation and still not functionally have too much ammonia first thing in the morning.
- 8:58What are those two?
- 8:59Just for the record...
- 9:01Oh, I think it's the, I forget the letters before and after, but I think it's the one that has the 360 and the 699 in the middle.
- 9:11Those are both upregulating CBS genes.
- 9:14And I will have to say that in my chronic, in my IC population who got the 23andMe results years ago when they gave you lots of data...
- 9:25100% of them had mutations, generally with both of those upregulating CBS genes.
- 9:33All right, good to know.
- 9:34And that's kind of what led me down the path of looking at the ammonia levels.
- 9:41I should say the goal for that first morning urine pH is 5.75 to 6.0.
- 9:50There are certain bacteria that favor a too low pH.
- 9:55For instance, let's talk about E. coli.
- 9:57It's very schizophrenic.
- 9:59Its favorite pH is 7.0.
- 10:03but its second favorite pH is 5.5.
- 10:08And this explains why some people who start getting a UTI and they're not in the chronic population, they can take cranberry juice, and it helps because they're lowering the pH.
- 10:20Cranberry has a pH of 2.6.
- 10:23So it's working, but if they keep taking the cranberry and they lower it too much to 5.5, oh, well the cranberry's not helping any longer.
- 10:32Why is that?
- 10:33Because the E. coli favor first choice 7.0, second choice 5.5.
- 10:42Have you ever been overwhelmed by supplements?
- 10:45Where to buy them, making sure they're authentic.
- 10:48You want professional grade ones?
- 10:50Well, I want to tell you about Dr. Allison Seebecker's Fullscript Dispensary.
- 10:54This is a place where you can get those types of high quality supplements that are vetted, no counterfeits here, and there are over 15,000 of them for you to choose from with exclusive pricing.
- 11:05She's also created community plans with suggestions for some of the favorite conditions like
- 11:10allergies, SIBO, IBS, UTIs, you know, the whole alphabet.
- 11:14So check it out.
- 11:15It's in the links below.
- 11:17And it is one of the best ways to get your supplements delivered to your door.
- 11:21And remember, exclusive pricing.
- 11:24Okay, see you there.
- 11:27I have like no words.
- 11:28Okay.
- 11:29I mean, wow.
- 11:30Thank you for doing this work.
- 11:32It is really so precious and so important.
- 11:37And I so appreciate it.
- 11:38Wow.
- 11:39And I want to thank Dr. Anne Hill, who's the one who told me about you like years ago.
- 11:43Wow.
- 11:43She was like, oh, yeah, you know, Ruth, Chris, yeah.
- 11:46And then I thought about you a lot because I'm getting word out about small intestinal bacterial overgrowth and other chronic conditions.
- 11:53My company's Chronic Condition Rescue.
- 11:54I have SIBO SOS.
- 11:55And then fast forward after, you know, my 12th summit, I did the menopause, the new science and wisdom of menopause summit.
- 12:04And...
- 12:05This is how it happens.
- 12:07My friend, Stephen Wright with the healthy gut was like, Siobhan, you really, cause his wife was in the summit.
- 12:12And so, and he's been in many of mine.
- 12:14He's like, you really need to talk to this lady about, you know, interstitial cystitis and everything.
- 12:19And I'm like, Ruth Chris.
- 12:20He's like, yeah, she's great.
- 12:21I talked to her.
- 12:23I'm like, yeah, I'm like, hook me up.
- 12:26So that's how we got the intro.
- 12:27And of course I could have done that through Ann Hill, but anyway, that's how it all came together because
- 12:31I think the universe wanted us to have this conversation and whoever's watching this, the, the, you're here for a reason.
- 12:39Okay.
- 12:39Spread the word.
- 12:41So this older woman who, uh, I am her primary caregiver for, uh,
- 12:47She's about to turn, she'll kill me 80.
- 12:50And she had all these UTIs and she went to the gynecologist, right?
- 12:55Typical, you know, you pee in the cup, they come back, they say, well, we're going to culture it a few days later.
- 12:59They, they're, they're like, but in the meanwhile, take this to help you out.
- 13:03And then, and don't take the Azo first because we won't get the right culture, blah, blah.
- 13:08Oh, we don't know what it is.
- 13:09Try this.
- 13:10Oh, it did, you know, contaminated, all these things.
- 13:15They send her, they did it so many times, they send her to a urologist.
- 13:18In the urologist's office, pee in a cup, discuss things.
- 13:25Typical situation.
- 13:26They think they found it.
- 13:27Nope, they didn't think they found it.
- 13:29On the urologist's front desk or side desk, there's a little brochure holder with the micro Gen DX lab information.
- 13:37Now I already knew about micro Gen DX because of you and a couple of other things.
- 13:43And I called.
- 13:45After the first test was like a no-go.
- 13:48And I said, hey, I remember you guys have these Microgen DX brochures.
- 13:52Can she get tested that way?
- 13:54And the woman was like, sure.
- 13:55We don't usually offer it because insurance doesn't cover it.
- 14:00And I'm like, she's now had this darn thing for six months.
- 14:04She's losing her mind.
- 14:07Is it worth 350 bucks or however much it is to get the right answers?
- 14:12Because the rest of the science isn't supporting you.
- 14:15And kudos to you for having the brochure in the office to begin with.
- 14:18But could you offer it up to everybody as an option?
- 14:20Let me decide.
- 14:22Let the patient decide.
- 14:23Right.
- 14:24And so I went and had to pick up the kit there and all that jazz before I realized you can order it at home.
- 14:30And so they found out the proper thing and she did a round of antibiotics and she was one of the lucky ones.
- 14:36She got it resolved.
- 14:37Absolutely.
- 14:38It's $249 for an individual kit.
- 14:43I recommend that women testing for the first time do the women's key kit.
- 14:48which is 279, but that's a great bargain because it tests both the urine and the vagina.
- 14:56Now for men with a UTI, there's a men's key kit that checks the semen and the urine because for most men, their urinary tract infections are being caused by retrograde ejaculation and the source of the infection is in their prostate.
- 15:14And by the way, men who have the CBS problem have high ammonia levels, that's contributing to their retrograde ejaculation.
- 15:25We also are seeing some very exciting results with men who've been diagnosed with prostate cancer,
- 15:32One man was told that he had to have his prostate out.
- 15:36Two were told they had to have radiation.
- 15:38I don't remember what the fourth guy was told, but their practitioner did microgen testing on their semen.
- 15:45100% of them had infection.
- 15:48They were asymptomatic.
- 15:51We treated the infections.
- 15:53Their PSA went back to normal.
- 15:55None of them had to have any intervention for their prostate cancer.
- 16:01Oh my goodness.
- 16:04People.
- 16:05Tell the world.
- 16:07Tell the world about this.
- 16:10Are you kidding me?
- 16:11Not to diminish those people who actually do have prostate cancer for reasons, of course.
- 16:16But what if?
- 16:18The Gleason score is the stage of the biopsy with the cancer cells and how much they find and how aggressive it is, plus the PSA.
- 16:31So if you bring the PSA down...
- 16:35Many men who are getting intervention for their prostate cancer due to a high PSA due to infection, maybe that's not the appropriate intervention for them.
- 16:47Right.
- 16:48These stealth infections in these villages of biofilms that we all have the villages of biofilms at a different varying levels.
- 16:56But Dr. Allison Seebecker and I, who do so many projects together, she's truly a SIBO.
- 17:01She's to SIBO what you are to UTIs and IC.
- 17:06And she and I are not obsessed, but in a healthy way, very interested in stealth infections.
- 17:12And so is Dr. Anne Hill.
- 17:17and getting this information out.
- 17:19I'm going to do my darndest to make sure that as many people as possible in the world see this and hear this.
- 17:23By the way, this was not sponsored by MicroGenDX.
- 17:26Welcome if you would like to sponsor.
- 17:28Feel free, sirs and nuts of loodies and kids.
- 17:31I mean, sure.
- 17:32But the fact is, is that this information is invaluable.
- 17:37And by the way, last thing, because the Women's Key does also test for...
- 17:45bacterial vaginosis, BV.
- 17:48Can I talk about that a little bit before I let you go?
- 17:50Absolutely.
- 17:52I think that BV is a misnomer because what I'm finding is that Gardnerella is not the big player.
- 18:00It's other bacteria.
- 18:02So there are many other pathogens that like to colonize the vagina besides Gardnerella or Prevotella.
- 18:09And
- 18:10And the only tools that these, that GYNs usually have in their toolbox are metrogel and fluconazole.
- 18:23And so that may work for some of the pathogens, but...
- 18:29It's not going to work for the pathogens that are now colonizing a vagina because the pH of the vagina is too high.
- 18:36So if you've been taking antibiotics and you've wiped out the good lactobacilli in your vagina, now the pathogens take up residence that like a higher pH because they're not getting it brought down by the lactic acid.
- 18:52And so it becomes a vicious cycle.
- 18:55So Microgen is going to find those other bacteria that are in the vagina that the standard BV tests are going to miss.
- 19:05And oftentimes we can have compounded vaginal suppositories for those pathogens.
- 19:12Or in the vast majority of times, simply acidifying the vaginal tract and,
- 19:20is sufficient to make the bad guys go away and encourage the good bacteria to grow.
- 19:26Now, if you don't have any good bacteria to begin with, that does have to be recolonized.
- 19:32And that's a whole separate discussion on the protocol for doing that.
- 19:37With the, like, boric acid... No.
- 19:41The pH is too high.
- 19:42There you go.
- 19:44Boric acid...
- 19:45The ideal pH for a vaginal tract is 3.8 to 4.2.
- 19:50There are vaginal pH test strips.
- 19:53They're on the Femologist website, lest you get confused by the 30 choices on Amazon.
- 20:00To acidify a vaginal tract...
- 20:03below 4.2, if you use boric acid, its pH is only 5.1.
- 20:10If you use lactic acid suppositories, which I know are readily available in other countries, that pH is 4.0.
- 20:20If you're using ascorbic acid, that may be a little too acidic for a postmenopausal woman, that's only 2.6.
- 20:30But apple cider vinegar douching at a pH of 3.2 works beautifully to acidify a vaginal tract, encourage the growth of healthy lactobacilli, discourage the growth of the bad guys.
- 20:46How long do you do it for?
- 20:48Until you get the desired pH, two to three times a week, not during a period.
- 20:54And once the pH is in that 3.8 to 4.2 range, you know you've adequately recolonized so it can be a self-sustaining system.
- 21:05So really, you know, there's a famous person out there saying that the vagina is a self-cleaning oven.
- 21:11It's not.
- 21:12No, you need the lactobacilli at least 90% of a medium load on the microgen vaginal test.
- 21:21Okay.
- 21:22Nor is it that all douches are bad because you just said that, right?
- 21:26So like, remember when it was like Eves or whatever the names were back in the day?
- 21:33No, we're not using it like body deodorant.
- 21:38No, it's not active.
- 21:41No, we're just trying to restore an environment where the healthy bacteria can flourish and the unhealthy ones will be discouraged.
- 21:50Okay.
- 21:51Is that apple cider vinegar diluted?
- 21:54It is.
- 21:55There are recipes online.
- 21:58I have a protocol I should probably put on my website.
- 22:01I did find, by the way, on the website under for patients, lo and behold, we did put up there.
- 22:11the collection guidelines for recurrent UTIs and IC in females, the semen and urine collection procedure for men.
- 22:21So all of these are written up.
- 22:24By the way, it's what you think it is, everybody.
- 22:26Yeah.
- 22:27Okay, just so you know.
- 22:28He's got a cup.
- 22:29There you go.
- 22:31Well, actually, it doesn't have to be backing off in a cup.
- 22:38For the men...
- 22:40I forget.
- 22:41I mean, my husband would never, that would not have worked.
- 22:45So what can you do?
- 22:46You get an unlubricated condom.
- 22:49The female can assist.
- 22:52After ejaculating in the unlubricated condom, when it can be carefully removed, he's not quite as erect.
- 23:00Very carefully removed.
- 23:03Take that little collection reservoir at the very bottom.
- 23:07Cut off the very end of it.
- 23:09Milk the semen into the cup.
- 23:11Extremely practical.
- 23:13And much less contamination than we get with them going directly in the cup.
- 23:18Really?
- 23:20Yeah, usually.
- 23:20Yeah.
- 23:21That's great.
- 23:22Not as much the skin for it.
- 23:24Yeah.
- 23:25Honey, that's a great tip.
- 23:29I'm a eight-year-old at heart, okay?
- 23:31All right, I'm in eighth grade.
- 23:32What do you want from me?
- 23:35Okay, you guys, if you don't know me, now you do, okay?
- 23:38Because I'm a cornball, and I'm easily amused.
- 23:41And I am so grateful that you were here, Ruth.
- 23:44Blessings to you.
- 23:46Godspeed with your projects.
- 23:47Oh, thank you.
- 23:49Seriously, please put the apple cider vinegar douche protocol on the site.
- 23:55You're meeting with your website designer.
- 23:58Tomorrow, yeah.
- 24:00I'm trying to remember.
- 24:01I think it's like three-quarters...
- 24:05No, I don't even want to say the amounts, but it's like there's a small amount, like a tablespoon or three quarters in eight ounces of warm water.
- 24:15It's not your salad dressing.
- 24:17And they do sell the apple cider vinegar douche little containers at drugstores and at Amazon.
- 24:24They're about three, four bucks.
- 24:26I have people just use that, wash it out, mix up their own solution, and then reuse it.
- 24:32Okay.
- 24:32Yeah.
- 24:32Because the container is kind of handy to have.
- 24:34Yeah.
- 24:35It's not, I mean, the vagina is not a sterile area.
- 24:38No, but so don't, do you use the formula from the... Yeah, you can.
- 24:43Okay.
- 24:43Absolutely.
- 24:44Clean the apparatus and you can reuse it a couple more times.
- 24:48With your own recipe for the apple cider vinegar douche.
- 24:51There's some things for our mothers and grandmothers maybe should not have fallen by the wayside.
- 24:59Some things were really whacked and some were really good.
- 25:01What can we say?
- 25:02Okay, bonus content, because I know we have to go.
- 25:05But for the people who have gone down that road of self-catheterizing, using the Infuserve America, I'll keep you just for two more minutes.
- 25:17What do you have in terms of tips?
- 25:18Because that is not for the week.
- 25:22I have a protocol.
- 25:24I don't know if you were given that or not.
- 25:27But I will say that there's a mirror that you could get that's standing that's on Amazon that has great amplification.
- 25:36And many women find you put a towel down in the bathtub and lean back.
- 25:41Put your mirror there.
- 25:42And that way, when you put the catheter in, you know you're in the bladder.
- 25:45When some urine comes out, it just runs down the drain.
- 25:48And then you put in the medicine.
- 25:50Yep.
- 25:51There's also Glido, which Dr. Anne Hill turned me on to, that you can get from Infuserve America, which is a lidocaine lubricant.
- 25:59Yep.
- 25:59And that helps.
- 26:01And then what if there's a little bit of blood?
- 26:05It doesn't happen very often, but we don't have the same urethras.
- 26:11And therefore, people often need, not often, but occasionally need a different size catheter.
- 26:18So if there is any blood, I question if the size of the catheter that's being dispensed is a little too large for your particular anatomy.
- 26:28Okay.
- 26:28Okay.
- 26:29And they do have, so that's a pediatric, but they haven't, that they usually send.
- 26:34They also do have an infant size.
- 26:36I can't believe we're having this personal conversation, but I'm here to help.
- 26:39And so it's very flexible.
- 26:42So it's a little bit harder to maneuver, but that also may be an answer.
- 26:47If you find you're thinking pediatric, it's so small, it should be fine, but maybe you need a smaller one.
- 26:52And they do make infant ones, which by the way,
- 26:55broke my heart to think that a child or baby would ever need this, but nevertheless, their own situations.
- 27:00There's also a device called a Eurodapter, U-R-O-D-A-P-T-E-R.
- 27:06They used to be available on Amazon.
- 27:08There's now a place in Florida that distributes them
- 27:12but they're more expensive than they should be.
- 27:16I do have some patients that find that the ear adapters are brilliant because it's like a little tiny funnel, but it only has a very little lip that goes into the urethra.
- 27:29And then you can just put the syringe with the medicine right on the ear adapter and dispense it into the bladder without ever using a catheter.
- 27:39That has my name all over if I ever have to fall down this rattle again.
- 27:42I actually thought of them.
- 27:45I was like, could we just do this?
- 27:47So thank you for telling me that.
- 27:49That's why I needed to finish this conversation with that.
- 27:53I hope that whoever is listening to this never needs this information.
- 27:57From the bottom of my heart and soul, I say this to you.
- 28:01But if you do, because we are on a physical planet with physical anatomy and with bacteria and viruses and biofilms that we share this sacred space with.
- 28:12I hope that this helps move you forward out of pain, out of agony, out of misery, out of a personal hell that I have only had a glimpse of and I never want to see it again.
- 28:27So many blessings to you, Ruth.
- 28:29Many blessings.
- 28:30Well, thank you so much for getting the word out there.
- 28:32And we are seeing fabulous results.
- 28:36We had a lady in Texas whose urologist wanted to remove her bladder.
- 28:41We did the microgen testing, worked on the biofilms.
- 28:45Four months later, she's pain-free for the first time in decades.
- 28:49So there is hope, but I want people to know that.
- 28:52Maybe you haven't been given hope by the urological community that doesn't
- 28:59quite understand biofilms yet, but we're really trying hard to educate.
- 29:04And thank you, Siobhan, for being part of getting that word out there that this is how infections live in people, and we can address that.
- 29:14And the same old antibiotics that have always worked will still work if we break down the biofilms.
- 29:21Great way to wrap it.
- 29:22Right.
- 29:22That's such a good point.
- 29:23I don't know if we made that soon enough.
- 29:24So thank you for hanging in to the end of this recording.
- 29:28Those antibiotics are not evil, right?
- 29:32They just need to be worked with properly.
- 29:33So get that week of the biofilm busting in so that then they have the opportunity to do the job.
- 29:40But you're saying Bactrid is not the one.
- 29:44MacroBid.
- 29:45MacroBid.
- 29:46Well, not only that, but the product insert says it requires an acid pH to work.
- 29:53Well, this population with high ammonia doesn't have an acid pH.
- 29:59So I knew intuitively for decades that in this chronic population, the MacroBid wasn't working.
- 30:06I just couldn't explain why.
- 30:08Now I know why.
- 30:10I don't think we've been doing the best job treating infections because of the way we're dosing the antibiotics.
- 30:17If you tell someone to take an antibiotic twice a day, most people think, oh, I'll take it at breakfast and at dinner.
- 30:25But because different antibiotics have different half-lives, how long, 50% of it will stay in your body.
- 30:33And let's say it's
- 30:36Four hours.
- 30:37Okay, so four hours later, you only have half as much.
- 30:41Eight hours later, you only have a quarter as much.
- 30:44Four hours after that, you're only gonna have a 16th as much.
- 30:48So there's a half-life and a length of time it's gonna take for that antibiotic to clear your body.
- 30:55So if you take that second dose of antibiotics at dinner time, by the time you go to bed, you don't have as much of that antibiotic on board
- 31:05to accumulate in your bladder overnight.
- 31:09So I've been telling practitioners to prescribe the antibiotics.
- 31:14If they're twice a day, they take that second dose at bedtime.
- 31:18That ensures that you have the most antibiotic in the highest concentration in the bladder for the longest number of hours.
- 31:28You will have a better clinical effect with that antibiotic killing the bacteria
- 31:34the longer you can keep a higher concentration rate where the infection is.
- 31:40And when you get the microgen DX test, it tells you what antibiotics are appropriate for the bacterial overgrowth infection that you have.
- 31:52Right, right.
- 31:53Except for New York state, but we engineer around that and use other resources.
- 31:59Okay.
- 32:02Antibiotic options, you still need to have somebody familiar with pharmacology.
- 32:10They just tell you what works on a culture plate.
- 32:12Right, exactly.
- 32:13May not be the same as what works in a person's body.
- 32:17For instance, the macrolides, azithromycin may work on many of these pathogens, but only
- 32:266% to 8% of that antibiotic even makes it into the urinary tract.
- 32:31So it would not be a good antibiotic choice for someone with a urinary tract infection, whereas it might be the perfect choice for somebody with a respiratory infection that is sensitive to that antibiotic.
- 32:44So there has to be some discernment there.
- 32:46We have the same issue with practitioners who have a prostatitis.
- 32:52Not all antibiotics have good prostate penetration.
- 32:56So you need somebody who knows enough pharmacology, and I have resources for the practitioners I consult with on a whole list of which ones have good prostate penetration.
- 33:10And I'm working on a whole master guideline for practitioners that...
- 33:15to look at antibiotic choices for the women, because some of these antibiotics are very destructive to healthy lactobacilli in the gut and the vagina, but we have some other choices that actually don't kill lactobacilli.
- 33:31So if we have a choice between those, you know
- 33:36A third generation cephalosporin that protects against certain types of drug resistance and doesn't trash healthy lactobacilli is a winner.
- 33:48And what do you do for probiotics?
- 33:50Do you have a preference for probiotics after the courses?
- 33:55Well, actually, I want people to be taking probiotics while they're on the antibiotic.
- 33:59They just separate it by at least two hours.
- 34:04The safest one is going to be one that contains Saccharomyces boulardii, although you can add Saccharomyces boulardii in separately.
- 34:15Okay.
- 34:17It turns out that the gut needs to be replenished with healthy lactobacilli on an ongoing basis, particularly if you're going to do a two-week course of antibiotics.
- 34:29You don't want to wait to the end until you start doing that.
- 34:32Orthomolecular makes one called probiotic that has a combination of
- 34:38They are shelf stable.
- 34:39I like that because you don't put it in the refrigerator and forget them.
- 34:42It's called probiotic.
- 34:44And if I pull up my website here and we go down to here, this is from Femologist that has my products.
- 34:55We have the ones that disrupt fibrin.
- 34:58We have the ones that disrupt extracellular DNA, the ones that disrupt the amyloid fibers, and
- 35:07people who have elevated lipoprotein little a, the products they need, bring that down.
- 35:12Here's the ammonia scavenger and the plain ornithine and the plain citrulline that are available.
- 35:20If club Ciela comes back, good studies showing that taurine helps clear that out of the gut and the bladder, how to prevent them in the future,
- 35:30Here are the oral probiotics.
- 35:32So here's the orthobiotic that has the lactobacilli plus Saccharomyces boulardii.
- 35:39This is a great one to take if you're on an antibiotic.
- 35:43This is a great one, one a day, as a maintenance, just to keep a healthy gut.
- 35:48And then this is my rescue remedy.
- 35:51If you get any loose stools while you're on an antibiotic, you take one of these.
- 35:56These are packets that go in water with powder, and you drink it one a day until...
- 36:02you've had no gut issues for three days and there's 15 packets in a box.
- 36:08And this is going to keep you from getting in trouble with C. diff or diarrhea from the antibiotic.
- 36:18Most of the time, if people are good about taking probiotics, you don't have any gut issues when you're on an antibiotic.
- 36:27Okay, but if you're depleted.
- 36:29What if, now were you saying before that the lactobacillus can be overgrown in the vaginal canal?
- 36:37Oh yes, you can have too much of a good thing.
- 36:40Okay.
- 36:40So if people have an overgrowth of lactobacilli, the report coming back instead of a medium load will say you have a high load.
- 36:49And once again, you don't have to have an antibiotic.
- 36:52All you do is alter the pH.
- 36:54A baking soda douche will wipe out a substantial amount of that overgrowth
- 37:02And once again, most people only have to do it once.
- 37:05But if the pH is below 3.8, you know you still have too much lactobacilli and you might want to do an additional baking soda douche.
- 37:16And did you just say 2.8?
- 37:193.8.
- 37:20Excuse me.
- 37:21Great.
- 37:21No, I think you said it right.
- 37:23Okay.
- 37:23Yeah.
- 37:24All right, ladies and gents, we got to go.
- 37:26But thank you, Ruth.
- 37:26I appreciate you being this last with me.
- 37:29All right.
- 37:29We'll talk to you later.
- 37:30Take good care.
- 37:31Bye-bye.
- 37:32Bye.
- 37:32Thank you.
- 37:33So that's a wrap on today's episode.
- 37:35Thank you so much for being here.
- 37:37It genuinely means everything to me.
- 37:39If something in this conversation sparks something for you, share it with a woman or a guy in your life who needs to hear it.
- 37:46That's how this show grows.
- 37:47That's how we heal the planet together.
- 37:49And that's how we really connect.
- 37:50For more resources, free tools, and everything we talked about today, head over to SiobhanSarna.com.
- 37:56That's S-H-I-V-A-N-S-A-R-N-A dot com.
- 38:00It's all there waiting for you.
- 38:02And until next time, keep asking the questions, keep finding the answers.
- 38:05You deserve the full picture and the very best.
- 38:08Namaste.
- 38:09you