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Week 13 2025 College Football Picks for the 10 Biggest Games!
Week 13 may look light on paper, but several matchups carry major playoff weight — and we’re breaking down the 10 biggest games of the weekend with full analysis, stats, and against-the-spread picks.Missouri travels to Oklahoma in a fascinating clash of elite defenses and shaky offenses. SMU and Louisville battle for ACC positioning, while USC heads to Oregon in a potential playoff elimination game. Arkansas tries to shock Texas in Austin, Kentucky looks to stay hot at Vanderbilt, and TCU aims to rebound against a surging Houston team. Pitt’s improving offense gets Georgia Tech’s vulnerable…
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