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Latest / This Is Why with Dr. Busti

SSRI Antidepressants: Pharmacology Made Easy & Clinically Relevant

In this This Is Why pharmacology review, Dr. Busti walks through the Selective Serotonin Reuptake Inhibitors (SSRIs)—how they became first-line for major depressive disorder and a wide range of anxiety-related disorders, and where their real-world pitfalls live.

We compare the core agents—citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline—covering indications, mechanism, and clinical nuances that matter at the bedside. You’ll learn how dose, half-life, metabolism, and side-effect patterns influence patient-specific choices, and what to monitor for safety and…

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