Statins (HMG-CoA Reductase Inhibitors): LDL Lowering Made Easy

This Is Why with Dr. Busti · Jan 20, 2026 · 1h 3m

Statins (HMG-CoA Reductase Inhibitors) are the foundation of LDL lowering and ASCVD prevention. In this lecture from This is Why, Dr. Busti will make statin pharmacology easy to understand, but also clinically relevant in the proper context of the evidence. The use of HMG CoA reductase inhibitors: atorvastatin, rosuvastatin, simvastatin, pitavastatin, and pravastatin are drugs in this drug class that Dr. Busti will review.

You’ll learn how to:

MOA: How HMG-CoA reductase inhibitors reduce hepatic cholesterol synthesis and increase LDL clearance

Clinical uses: Hyperlipidemia treatment, primary…