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The Onion Peel: Melatonin for Endometriosis? S1E5
Melatonin and Endometriosis: What the Research Actually Says
In this Onion Peel bonus episode of the Pain Free Periods podcast, host Stasha reviews an Instagram claim that melatonin reduces endometriosis lesion growth by blocking EGFR. She summarizes a 2024 Journal of Pineal Research study reporting that melatonin inhibited endometriosis lesion growth in mouse models and human cell lines by stably binding EGFR, blocking its activation and downstream survival signaling, and lowering cyclin D1 to limit cell division; the researchers suggested melatonin as a potential novel therapy. She also…
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