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Wisdom Wednesdays: How to train your immune system's 'sniper cells' · Hardiness with Dr Paul Taylor

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  Speaker 1: Hey, everybody, Welcome to another edition of Wisdom Wednesdays, and
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  Speaker 1: today I want to talk about a new study that
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  Speaker 1: shows how our bodies internal systems are connected in ways
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  Speaker 1: that we are only just beginning to understand. So a
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  Speaker 1: new study out of Australia is showing us that what
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  Speaker 1: we eat doesn't just affect our wasteline or our mood.
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  Speaker 1: It actually influences how our immune system operates and how
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  Speaker 1: our sniper sales. Our most immune warriors are controlled, informed
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  Speaker 1: and supported. So let's dive in. The study I'm talking
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  Speaker 1: about comes from the team at the Dottary Institute for
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  Speaker 1: Infection and Immunity at the University of Melbourne. Their work
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  Speaker 1: was published in the journal Immunity, and the news piece
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  Speaker 1: about it is titled Gut Control System Sniper Cells by
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  Speaker 1: Remote Control. Here's what they found. They showed that diatary
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  Speaker 1: fiber coming from vegetables, legomes, fermented foods, these sorts of
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  Speaker 1: things plays a critical role and specifically the fiber is
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  Speaker 1: used by the gut microbiome short chain fatty acids such
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  Speaker 1: as beauty. It now that we've known for many, many years,
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  Speaker 1: and I've talked about that before, but what they found
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  Speaker 1: in this study is that those short chain fatty acids
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  Speaker 1: that are produced by your gut microbiome when they digest fiber,
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  Speaker 1: they then travel into the bloodstream and ultimately enhance the
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  Speaker 1: precision and potency of what's called our killer taase cells.
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  Speaker 1: So these you may have probably heard of them, especially
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  Speaker 1: because of COVID. These are the immune sniper cells, the
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  Speaker 1: killer cells that are part of our immune system, and
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  Speaker 1: they play significant roles in models of cancer. Now, importantly,
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  Speaker 1: the study found that it wasn't simply the presence or
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  Speaker 1: absence of specific gut bacteria that determined the outcomes. Instead,
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  Speaker 1: it was what those bacteria were be producing, the short
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  Speaker 1: chain fatty acids that really mattered. And from a clinical perspective,
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  Speaker 1: patients with higher buttorate levels, which reflects the higher fiber
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  Speaker 1: intake and active gut microcrobial metabolism, they responded better to immunotherapy,
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  Speaker 1: particularly for melanoma, which is a very aggressive cancer. So
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  Speaker 1: the implication is pretty big for all of us that
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  Speaker 1: gut is not just digesting food and passing nutrients, it's
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  Speaker 1: actually sending metabolic messages far beyond itself to our immune system.
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  Speaker 1: And I've told about how eighty percent of your immune
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  Speaker 1: system resides at the gut barrier, and it turns out
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  Speaker 1: that this is really really critical in ways that we
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  Speaker 1: didn't understand. That those messages that are coming from the
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  Speaker 1: gut to the immune system influence how well our rest
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  Speaker 1: body respawn to major threats like cancer and likely many
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  Speaker 1: other immune challenges. Right, so, just because this was done
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  Speaker 1: on cancer doesn't mean it's just limited to this. It
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  Speaker 1: is actually training the natural natural killer sales of your
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  Speaker 1: immune system, which are hugely important in combating all sorts
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  Speaker 1: of So why I should be kurt, Well, there's really
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  Speaker 1: three big reasons. The first is that you can really
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  Speaker 1: influence your immune system through your diet. This research gives
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  Speaker 1: us something really actionable. It reinforces the idea that what
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  Speaker 1: we eat, especially five, doesn't just keep us healthy in
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  Speaker 1: a generic sense. It actively supports our immune system's elite
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  Speaker 1: killer cells. And we're seeing the mechanism as such that
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  Speaker 1: the fiber that you eat feeds certain microbes that then
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  Speaker 1: produce these short chain fatty acids that results in stronger,
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  Speaker 1: more precise T cells immr immune system. And this really
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  Speaker 1: makes us rethink the gut immune connection. Many people think
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  Speaker 1: gut health means digestion, bloating, and maybe influences their mood.
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  Speaker 1: But this shows that the guts rates extends into classic
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  Speaker 1: the kind we associated with batting infection or cancer. And
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  Speaker 1: then the third one is really about prevention and resilience,
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  Speaker 1: even if you're not facing cancer or serious disease right now.
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  Speaker 1: This research suggests that building a gut environment that supports
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  Speaker 1: these beneficial pathways actually booster your long term health resilience.
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  Speaker 1: And one way to think of it is that the
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  Speaker 1: body has got better sniper cells ready or ready they
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  Speaker 1: are waiting for something to come in so that it
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  Speaker 1: can actually act. So the take on message is clear.
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  Speaker 1: One is to prioritize fiber rich foods, making sure you've
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  Speaker 1: got plenty of vegetables, leg goomes and fermented foods, and
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  Speaker 1: real whole grains, not breakfast cereals, but real whole grains,
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  Speaker 1: because these are the substrates that the gut microbes use
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  Speaker 1: to produce these beneficial short chain fary acids like and
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  Speaker 1: I've talked about before about beatay it and other short
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  Speaker 1: chain fairy acids are good for your gut lining, they're
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  Speaker 1: good for your heart, they're good for your brain. We
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  Speaker 1: now know they're good for your immune system, and we
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  Speaker 1: really need to think of our gut microbiome as an
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  Speaker 1: important ally in our health, moving the bad bugs or
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  Speaker 1: taking probiotics. It's actually about supporting your overall gut function.
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  Speaker 1: And we know that diversity is really important. But we
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  Speaker 1: also know that regular physical activity actually changes your microbiome
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  Speaker 1: in positive ways, as does good sleep, and if you've
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  Speaker 1: got shithouse physically active, your microbiome actually degrades. And what
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  Speaker 1: we're seeing really with this research is that we often
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  Speaker 1: activate our immune system when something happens, like whether it's
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  Speaker 1: illness or infection. But these stress research is telling us
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  Speaker 1: that the preparation the ground works well ahead of time.
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  Speaker 1: It's just like the army of an issue being trained
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  Speaker 1: well so that it can respond whenever stuff happens. These
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  Speaker 1: sniper cells don't just appear overnight, They actually evolve over time.
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  Speaker 1: So this is just another reason if we needed another one.
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  Speaker 1: You're eating a healthy diet with a large range of
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  Speaker 1: foods and making sure that you're having reasonable fiber intake
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  Speaker 1: because your immune system will love you for it, particularly
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  Speaker 1: when you need your immune system the most. That's it
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  Speaker 1: for this week, folks, Catch you next time.