Latest / Hardiness with Dr Paul Taylor / Wisdom Wednesdays: A super simple measure that's a big predictor of your longevity
Transcript
- 0:09Speaker 1: Hey, everyone, welcome to another edition of Wisdom Wednesdays. Today's session,
- 0:14Speaker 1: I am going to try to convince you to update
- 0:17Speaker 1: your present list for Santa and stick a hand grip.
- 0:21Speaker 2: Dynamometer on there.
- 0:23Speaker 1: Now, you will have heard me talk before about strength
- 0:26Speaker 1: training and muscle mass is critical to aging well. But
- 0:30Speaker 1: today I want to talk about a really fascinating study
- 0:32Speaker 1: that's just been published that really brings this point home
- 0:36Speaker 1: and gives us a tool that is so simple, so cheap,
- 0:40Speaker 1: and so powerful that it really should be in every
- 0:44Speaker 1: gpage toolkit. Every time you go to the doctor, they
- 0:48Speaker 1: should be measuring this, just like they measure your blood pressure.
- 0:52Speaker 1: So the research paper in question has just been published
- 0:56Speaker 1: in the American Journal of Preventative Cardiology and the title
- 1:01Speaker 1: of the paper is Grip Strength to Weight Ratio all
- 1:05Speaker 1: Cause and Cardiovascular mortality and Cardiovascular disease prevent Prevalence evidence
- 1:12Speaker 1: from n Ham's and Charles. So what they did in
- 1:16Speaker 1: this study was they looked at something called grip strength
- 1:20Speaker 1: to weight ratio or GSWRS I will refer to it.
- 1:25Speaker 1: And obviously it's a relationship with all cause mortality, cardiovascular death,
- 1:30Speaker 1: and the prevalence of cardiovascular disease. Now, we've known for
- 1:34Speaker 1: a while that grip strength is a useful biomarker, and
- 1:38Speaker 1: I've talked about this before. It's been linked to everything
- 1:41Speaker 1: from frailty prediction and falls, to heart disease, depression, and
- 1:46Speaker 1: even a very strong linked to dementia. But absolute grip strength,
- 1:51Speaker 1: like many things in health, isn't the full story. Because
- 1:55Speaker 1: bigger people tend to have higher grip strength, but does
- 1:58Speaker 1: that mean that they're healthier?
- 1:59Speaker 2: Will not always.
- 2:01Speaker 1: And what the researchers did in this study, which I loved,
- 2:05Speaker 1: was they normalized grip strength to body weight to get
- 2:09Speaker 1: a more individualized, more meaningful metric which they call GSWR
- 2:14Speaker 1: grip strength to weight ratio, and that is basically how
- 2:18Speaker 1: strong you are for your size, and that is a
- 2:21Speaker 1: much better predictive value for an individual on an individual basis.
- 2:27Speaker 1: So let's dive into the study. And what they did
- 2:31Speaker 1: was they analyzed data from these two massive nationally representative
- 2:36Speaker 1: cohorts and the US Enhange Study and the Chinese Charles Study,
- 2:43Speaker 1: And between the two, we're talking over twenty thousand individuals
- 2:47Speaker 1: that were followed for seven or eight years, and that's
- 2:50Speaker 1: a pretty strong data set and Obviously they were older
- 2:54Speaker 1: individuals because they were looking at things like cardiovascular these
- 2:57Speaker 1: and all cause mortality. Now, strength was measured with a
- 3:02Speaker 1: hand gripped dynamometer and you can actually buy them, and
- 3:05Speaker 1: we bought one in our house about a year ago
- 3:08Speaker 1: and a bit where we're using it.
- 3:12Speaker 2: You can buy one in.
- 3:14Speaker 1: Australia on Amazon for twenty nine Australian dollars. In the
- 3:18Speaker 1: States have checked it up, you can buy one for
- 3:21Speaker 1: nineteen US dollars and in the United Kingdom that come
- 3:24Speaker 1: as cheap as seventeen quid. Right, And here's how to
- 3:29Speaker 1: replicate what they did in the study. You get this dynamometer,
- 3:32Speaker 1: which is basically something that you squeeze and it measures
- 3:35Speaker 1: your force that you produce.
- 3:37Speaker 2: Typically in kilos.
- 3:39Speaker 1: And what you do is you stand upright and firmly
- 3:43Speaker 1: grasping the dynamometer with your elbow flex at ninety degrees,
- 3:47Speaker 1: so your kind of forearms sticking out from your body,
- 3:50Speaker 1: and then you squeeze the dynamometer as hard as you
- 3:54Speaker 1: possibly can for three to five seconds. And what it
- 3:57Speaker 1: will do is will record the max force that you
- 4:01Speaker 1: can produce, and typically it gives it in kilos. I'm
- 4:03Speaker 1: not sure if the US ones do it in pounds.
- 4:05Speaker 1: If it's pounds, then you just use that because it's normalized.
- 4:10Speaker 1: And what you do is you do it twice for
- 4:12Speaker 1: each hand, rest for thirty seconds in between, or you
- 4:14Speaker 1: could probably just go to the other hand and then
- 4:16Speaker 1: back and you get two two values reach one and
- 4:20Speaker 1: you pick the best of each hand. So you pick
- 4:24Speaker 1: the best for your right and the best for your left.
- 4:26Speaker 2: And then you add them up.
- 4:28Speaker 1: So say you were to get ninety kilos from your
- 4:31Speaker 1: left and eighty five for your right hand, you'd add
- 4:35Speaker 1: them up and that's one hundred and seventy five kilos,
- 4:37Speaker 1: and then you divide that by your body weight. Now
- 4:40Speaker 1: again in the United States, if it's measuring it in pounds,
- 4:43Speaker 1: that's fine. You just add up the total pounds in
- 4:46Speaker 1: this case would be about one hundred and eighty hundred
- 4:48Speaker 1: and ninety ish on each hand. You add that up
- 4:51Speaker 1: and then you divide it by your body weight, and
- 4:54Speaker 1: again your bodyweight.
- 4:55Speaker 2: Will be in kilos.
- 4:57Speaker 1: Or if you're doing the American one and they give
- 4:59Speaker 1: you the dynamoma in pounds, then you use your body
- 5:01Speaker 1: weighing pounds.
- 5:03Speaker 2: Now let's get.
- 5:04Speaker 1: Back to the study and what they did was they
- 5:08Speaker 1: tracked deaths all cause mortality, deaths from anything, and death
- 5:12Speaker 1: from cardiovascular disease, and they also assessed cardiovascular disease prevalence
- 5:17Speaker 1: using medical history. They used interviews in national mortality records,
- 5:22Speaker 1: and then they adjusted for all the usual suspects. So
- 5:27Speaker 1: this is important because these were adjusted for things such
- 5:29Speaker 1: as your age, your sex, your body mass index, hypertension, diabetes, smoking,
- 5:34Speaker 1: blood lipids, socioeconomic statius.
- 5:36Speaker 2: They did that lot and.
- 5:38Speaker 1: The results were seriously compelling compared to people. And what
- 5:44Speaker 1: they did is they separated them into quartiles, so the
- 5:47Speaker 1: lowest twenty five percent, then the low medium, the high medium,
- 5:53Speaker 1: and then the highest twenty five percent. Compared to people
- 5:57Speaker 1: in the lowest quartile, so the lowest twenty five percent
- 6:00Speaker 1: of the weakest twenty five percent. Those in the highest
- 6:03Speaker 1: quartile had a seventy three percent lower risk of dying
- 6:08Speaker 1: from any cause in the US cohort and a forty
- 6:14Speaker 1: seven percent lower risk of dying in the Chinese cohort,
- 6:19Speaker 1: and cardiovascular deaths were also dramatically lower in the US cohort.
- 6:24Speaker 1: The strongest twenty five percent had a seventy nine percent
- 6:30Speaker 1: risk reduction for cardiovascular deaths, right, and that is pretty bunkers.
- 6:38Speaker 2: So I'll give you the cutoffs.
- 6:39Speaker 1: Let's just look at the end he hits cohort, So
- 6:43Speaker 1: the lowest quartile.
- 6:44Speaker 2: Q one, when you do then hazard ratios for mortality.
- 6:49Speaker 1: And the Q two so twenty five to fifty percent
- 6:53Speaker 1: in terms of strength, so low the medium. Their hazard
- 6:57Speaker 1: ratio compared to Q one was not zero point four
- 7:01Speaker 1: to seven, so they had a fifty three percent reduced
- 7:06Speaker 1: all cause mortality than weaker So just going from the
- 7:11Speaker 1: weakest to the second weakest group reduced your risk of
- 7:16Speaker 1: all cause mortality by whopping fifty three percent, Like that
- 7:19Speaker 1: is bunkers. And Q three, which are those people sort
- 7:22Speaker 1: of fifty to seventy five percent, so they're above average.
- 7:27Speaker 1: Their hazard ratio was zero point three nine, so basically
- 7:31Speaker 1: they're sixty one percent less likely to die of anything
- 7:35Speaker 1: than the weakest group. And as I said, Q four
- 7:37Speaker 1: their hazard ratio was zero point twenty seven, so they
- 7:40Speaker 1: had a seventy three percent lower risk of all cause
- 7:43Speaker 1: mortality compared to the weakest groups. And that this is
- 7:48Speaker 1: just completely and ulterly bunkers in terms of the impact.
- 7:52Speaker 1: And when we look at the China study, and there
- 7:56Speaker 1: the Q four the strongest group. Their hazard ratio was
- 7:59Speaker 1: zero point five, so they are are forty seven percent
- 8:02Speaker 1: lower risk of death and everything. Why the difference in
- 8:06Speaker 1: the Canadian A sorry, in the Chinese versus the US,
- 8:09Speaker 1: Probably because the US population on the whole are on
- 8:12Speaker 1: the healthier because that they got a higher risk of
- 8:14Speaker 1: dying and therefore and that strength was more protective. But
- 8:20Speaker 1: just taking these things together and this is really impactful
- 8:25Speaker 1: and importantly, the researchers observed a classic L shape relationship,
- 8:30Speaker 1: meaning the biggest benefits come from getting out of the
- 8:34Speaker 1: lowest twenty five percent.
- 8:36Speaker 2: In other words, you don't need.
- 8:38Speaker 1: To be a gym bunny, you just got to be
- 8:40Speaker 1: stronger than the weakest twenty five percent. Personally, I think
- 8:45Speaker 1: this is huge implications for our exercise guidelines. So if
- 8:47Speaker 1: you take the data from Australia, the most recent data
- 8:53Speaker 1: showed that only twenty percent of Australian adults hit the
- 8:58Speaker 1: recommended guidelines for physical activity when it comes to strength training,
- 9:02Speaker 1: particularly in.
- 9:03Speaker 2: Older age groups.
- 9:05Speaker 1: Right, so only one in five are doing the recommended
- 9:09Speaker 1: two strength training sessions a week. About sixty percent actually
- 9:13Speaker 1: hit the baseline of one hundred and fifty minutes of
- 9:17Speaker 1: moderate physical activity a week, you know, so there's reasonable
- 9:20Speaker 1: amount who do that, but only one in five or
- 9:23Speaker 1: twenty percent actually do the strength training stuff. And this
- 9:26Speaker 1: should be a massive, massive wake up call. I mean,
- 9:30Speaker 1: here's the thing. If you have a job that involves
- 9:34Speaker 1: manual labor, you know, your grip strength is probably fine,
- 9:38Speaker 1: in fact, it's probably very good. But if you do
- 9:40Speaker 1: an office job and you're not in the gym lifting
- 9:44Speaker 1: heavy shit, the chances are that you are in one
- 9:47Speaker 1: of those lower two quartiles, and it's more important that
- 9:52Speaker 1: you do strength training. That is really important call to
- 9:55Speaker 1: action here for this, So I'm a big fan. Just
- 9:59Speaker 1: get a basic grip dynamometer online. As I said, it's
- 10:03Speaker 1: going to cost you twenty to thirty bucks depending on
- 10:05Speaker 1: where you are. Measure your grip from each hand, add
- 10:08Speaker 1: them together and then divide that by your body weight. Right,
- 10:12Speaker 1: So again it will give you your grip strength and kilos.
- 10:15Speaker 1: So you divide it in kilos and that is your GSWR.
- 10:19Speaker 2: So I'm having sure my value.
- 10:21Speaker 1: So my right hand was buying on fifty kilos, my
- 10:24Speaker 1: left hand was forty six point nine kilos, so that
- 10:27Speaker 1: gives me a combined force in the two hands of
- 10:31Speaker 1: ninety six point nine kilos divided by my body weight,
- 10:36Speaker 1: which is eighty gives me a GSWR of one point
- 10:39Speaker 1: two to one. So if you're doing any type of
- 10:41Speaker 1: strength training at all, you're likely to be above one
- 10:46Speaker 1: in terms of that cutoff. And in in our house,
- 10:49Speaker 1: everybody is above the cutoff for Q four. So Q
- 10:55Speaker 1: four is not zero point nine two or above right
- 11:00Speaker 1: ninety two percent of your body weight combined hands, you
- 11:04Speaker 1: are in the top quartile and are very very protective. Unfortunately,
- 11:08Speaker 1: the research paper didn't give us all of those cutoffs,
- 11:11Speaker 1: but I went in and looked at it and approximated it.
- 11:15Speaker 2: So they do these curves.
- 11:16Speaker 1: If you read the research paper, you can kind of
- 11:18Speaker 1: work it out from the graphs. So what I've worked
- 11:21Speaker 1: out is is the Q four, which they did say
- 11:23Speaker 1: that was above zero point nine two Q three is
- 11:28Speaker 1: not point eighty eight to not point nine.
- 11:31Speaker 2: Two Q two.
- 11:33Speaker 1: So this is where you're starting to get a little
- 11:36Speaker 1: bit into trouble. That was not point eight three to
- 11:39Speaker 1: not point eighty eight. And in Q one, the weakest group,
- 11:43Speaker 1: we're not point eight three. So if your combined force
- 11:46Speaker 1: from their left in your right hand is less than
- 11:49Speaker 1: zero point eight three. I would suggest that the most
- 11:52Speaker 1: important thing you need to do for your healthy get
- 11:54Speaker 1: yourself into the gym and start lifting heavy shit. Now
- 11:57Speaker 1: that's the data from the En Haynes quote. That's the
- 12:00Speaker 1: American one. I didn't actually do the data for the
- 12:03Speaker 1: Chinese one, but I think that's that's probably good enough
- 12:06Speaker 1: for everybody as a target to go. And this metric
- 12:10Speaker 1: is so powerful and so predictive and so easy to
- 12:13Speaker 1: measure that I think that it should be in every
- 12:16Speaker 1: single doctor surgery and they should do this in routine checkups.
- 12:21Speaker 1: I mean, you come in, they'll do your blood pressure,
- 12:23Speaker 1: some of them do your weight, and let's do your
- 12:26Speaker 1: comparison here, right, So blood pressure, Yes, we know that
- 12:30Speaker 1: elevator blood pressure increases the risk of stroke and heart disease,
- 12:34Speaker 1: but on its own, it's actually quite a poor predictor
- 12:37Speaker 1: of all cause mortality, and it can be quite variable.
- 12:41Speaker 1: Then fasting glucose or even he HbA one C. They
- 12:45Speaker 1: are strong predictors of diabetes risk, but again, many people
- 12:49Speaker 1: live in a gray zone for years, and they're not
- 12:51Speaker 1: actually very strong predictors of all cause mortality, and certainly
- 12:55Speaker 1: not as strong as this script. Strength LDL cholesterol with
- 12:59Speaker 1: many are obsessed with, has been associated with cardiovascular risk,
- 13:04Speaker 1: but half the people who have a heart attack have
- 13:07Speaker 1: normal LDL. And it's a really shit house predictor of
- 13:11Speaker 1: all cause mortality, particularly in older adults and in body
- 13:16Speaker 1: mass index, which you know we've been obsessed with for decades.
- 13:20Speaker 1: Don't even get me started on that shit. It is
- 13:23Speaker 1: such a blunt tool and such a poor predictor of cardiovascars,
- 13:28Speaker 1: the's mortality and all cause mortality. Now, compare that to
- 13:33Speaker 1: grip strength. So we talked about it in this paper,
- 13:36Speaker 1: but I'm going to give you some other evidence, right,
- 13:38Speaker 1: so this is not just a one off. A twenty
- 13:41Speaker 1: eighteen study in a British medical journal found that grip
- 13:44Speaker 1: strength was a better predictor of all cause mortality than
- 13:47Speaker 1: systolic blood pressure. Another study in the Lancet called the
- 13:51Speaker 1: Pure Study showed that grip strength was a strong predictor
- 13:54Speaker 1: of cardiovascular mortality than blood pressure or even physical activity.
- 13:59Speaker 1: So why isn't it standard in every clinic? I guess
- 14:03Speaker 1: that's the question. But strength training is clear that it matters,
- 14:07Speaker 1: and it matters more than we used to think. Now,
- 14:11Speaker 1: if your GSWR isn't where you want it to be.
- 14:14Speaker 1: Don't panic, but you do need to act. And it's
- 14:19Speaker 1: not about just hanging off a bar to improve your
- 14:22Speaker 1: grip strength. Really, grip strength is a proxy for engaging
- 14:28Speaker 1: in strength training. People who have high grip strength either
- 14:31Speaker 1: have done lots of strength training or they do lots
- 14:34Speaker 1: of physical labor, so they're using their muscles. And there
- 14:37Speaker 1: is a mountain of data that supports the idea that
- 14:42Speaker 1: good muscle strength is a really good predictor of not
- 14:47Speaker 1: just how long you're going to live, but also quality
- 14:49Speaker 1: of life as well. I've written extensively about this in
- 14:54Speaker 1: my latest book, The Hardiness Effect, and I've also talked
- 14:58Speaker 1: about it on a couple of different podcasts. But what
- 15:02Speaker 1: we know, for instance, a twenty seventeen study in the
- 15:05Speaker 1: Journals of Gerontology so that muscle strength is a stronger
- 15:09Speaker 1: predictor of longevity than muscle mass. So it's not about
- 15:13Speaker 1: big muscles, it's about how strong they are. And then
- 15:16Speaker 1: another meta analysis published in the European Journal of Preventive
- 15:20Speaker 1: Cardiology in twenty twenty two found that people with higher
- 15:24Speaker 1: muscle strength out of thirty one percent lower risk of
- 15:26Speaker 1: all cause mortality compared to those.
- 15:29Speaker 2: With the lowest levels.
- 15:30Speaker 1: Right now, in this study it was it was significantly
- 15:33Speaker 1: bigger than that. But when you see more and more evidence,
- 15:37Speaker 1: are different papers with results that are in a similar direction,
- 15:43Speaker 1: then we start to say, hey, this evidence is really
- 15:46Speaker 1: really strong and strength training. The benefits of strength training
- 15:50Speaker 1: are more pronounced in older adults. That leads to better
- 15:54Speaker 1: functional mobility, fewer falls, less realty, better glucose control, low inflammation,
- 16:01Speaker 1: and of course better grip strength. So the big take
- 16:05Speaker 1: up here is buy a hand grip dynamometer. They are
- 16:09Speaker 1: very cheap, you can get them on Amazon. Measure your
- 16:12Speaker 1: grip strength and calculate your GSWR. Then compare it to
- 16:16Speaker 1: the data that I talked about earlier on If you're
- 16:19Speaker 1: in the lowest quarter earlier that you're even Q two,
- 16:22Speaker 1: commit to change and start strength training twice a week.
- 16:25Speaker 1: We've shown that adults who engage in strength training twice
- 16:29Speaker 1: a week significantly improve their strength, particularly older adults. In
- 16:33Speaker 1: a world where we have warribles that track everything and
- 16:37Speaker 1: give us all of these different fancy diagnostics, sometimes the
- 16:40Speaker 1: simplest tools are the most powerful. So grab a grip
- 16:44Speaker 1: strength meter, pick up some weights and take control of
- 16:47Speaker 1: a metric that might just save your life or it
- 16:50Speaker 1: certainly will extend it and improve the quality of your life.
- 16:54Speaker 1: That's it for this week, folks, Catch you next time.