Likelihood Ratios (LR) Explained for Diagnostic Testing

This Is Why with Dr. Busti · Jul 2, 2026 · 24m

Likelihood ratios (LR) are one of the most clinically useful tools in diagnostic testing because they help clinicians determine whether a test meaningfully changes the probability of disease. In this episode of This Is Why with Dr. Busti, Dr. Anthony Busti explains how likelihood ratios integrate sensitivity, specificity, prevalence, and post-test probability into real-world clinical decision-making.

This Is Why understanding likelihood ratios (LR) matters for every clinician ordering diagnostic tests. Dr. Busti walks through how positive and negative likelihood ratios influence patient…