Latest / Trenches in Transplant Surgery
Liver Viability Testing with Ex Vivo Machine Perfusion
Ex vivo machine perfusion has ushered in a new era where a liver graft’s viability can be tested before the irreversible step of transplantation. Both normothermic and hypothermic perfusion techniques play roles in modern liver preservation, with NMP in particular enabling real-time functional evaluation. Key viability markers – lactate clearance, perfusate pH, glucose consumption, transaminase release, perfusion flow dynamics, bile production, and bile composition – have been identified through extensive research and are now applied in clinical decision-making. These markers, especially when…
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