Latest / This Is Why with Dr. Busti
TZDs (Pioglitazone) for Type 2 Diabetes: Pharmacology Review
In this lecture from This is Why, Dr. Busti will break down pioglitazone and the thiazolidinediones (TZDs) so you can confidently explain the mechanism, clinical use, side effects, and key contraindications for type 2 diabetes (T2DM).
You’ll learn how to:
- TZDs (pioglitazone): where they fit in type 2 diabetes (T2DM) therapy
- Mechanism of action: PPAR-γ agonist → increased insulin sensitivity (muscle/adipose) and improved glucose utilization
- Expected impact on A1C reduction and how long these drugs take to show benefit
- Practical comparisons: pioglitazone vs rosiglitazone
Side effects &…
The skinny
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