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Why Sulfonylureas Cause Hypoglycemia Explained

Why sulfonylureas cause hypoglycemia becomes much easier to understand once you know how pancreatic beta cells regulate insulin secretion. In this episode of This Is Why with Dr. Busti, we walk through a board-style pharmacology question that connects ATP-sensitive potassium channels, membrane depolarization, calcium influx, and insulin release into one clinically useful framework.

Instead of memorizing isolated diabetes medication facts, this episode explains the physiology behind insulin secretagogues and why missed meals can become dangerous in patients taking sulfonylureas or…

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