Latest / This Is Why with Dr. Busti
GISSI-3 Trial: ACE Inhibitors After MI Explained
ACE inhibitors after myocardial infarction — Dr. Busti explains the GISSI-3 trial and what it actually changed in clinical practice on this episode of This Is Why.
After the initial management of acute MI, the real question becomes: what else improves survival and prevents long-term damage? The GISSI-3 trial tackled this directly, evaluating early ACE inhibitor therapy and routine nitrate use in a large, real-world population.
Dr. Busti breaks down how lisinopril provided a modest but meaningful mortality benefit—and why that matters more than it seems. More importantly, we explore the why…
The skinny
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