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Combining NRP and NMP vs NMP Alone in DCD Liver Transplantation
Combining Normothermic Regional Perfusion (NRP) with Normothermic Machine Perfusion (NMP) in DCD liver transplantation offers synergistic benefits over NMP alone by providing both early in-situ resuscitation and ex-situ viability assessment. While NMP alone improves early graft function and logistics, it does not fully prevent ischemic cholangiopathy (IC); in contrast, NRP—by rapidly restoring oxygenated blood flow in the donor—virtually eliminates IC and significantly enhances biliary outcomes. Together, NRP+NMP yields superior graft survival, lower complication rates, and expanded use of…
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