Latest / Wits & Weights | Strength & Fat Loss Over 40 / The Surprising Truth About Diet Soda and Fat Loss (Can It Be GOOD for You?) | Ep 208
Transcript
- 0:07Philip Pape: you've heard that diet soda is terrible for you, that it causes cancer, weight gain and metabolic issues.
- 0:15Philip Pape: But what if conventional wisdom is not only wrong.
- 0:18Philip Pape: What if these cold, fizzy, zero calorie, artificially sweetened beverages could actually help you lose fat and improve your health?
- 0:25Philip Pape: Today, we're challenging assumptions to support the seemingly strange concept that, yes, diet soda can actually be a helpful tool.
- 0:32Philip Pape: Whether you're battling sugar cravings, trying to create a calorie deficit or simply looking for a guilt-free treat, this episode will give you the nuance and, very possibly, peace of mind you're looking for when it comes to diet soda.
- 0:54Philip Pape: Welcome to Wits and Weights, the podcast that blends evidence and engineering to help you build smart, efficient systems to achieve your dream physique.
- 0:58Philip Pape: I'm your host, philip Pape, and today we're diving into the controversial world of diet soda with my friends Dustin Lambert and Dwayne Ulrich from the Working Weights LLC podcast.
- 1:08Philip Pape: Go, follow it right now.
- 1:10Philip Pape: Pause, find it.
- 1:11Philip Pape: Follow it.
- 1:12Philip Pape: Dustin, who's been on the show before, is a strength and nutrition coach with over a decade of experience specializing in metabolic syndrome and helping countless clients transform their bodies.
- 1:22Philip Pape: He's also one of the best guys I know when it comes to unraveling nutrition research.
- 1:27Philip Pape: Dwayne is the everyday ombudsman on their podcast.
- 1:29Philip Pape: He's a renaissance man of sorts, having been a high school educator in history and science, a coach for track and field, softball, baseball, volleyball, soccer, everything except the Olympics, a firefighter, police officer and x-ray technician.
- 1:43Philip Pape: In short, I think he's ready for anything.
- 1:45Philip Pape: Today, we're going to discuss how diet soda can fit into a smart nutrition plan and examine the potential health benefits which might surprise you.
- 1:53Philip Pape: We'll also dive into the evidence on artificial sweeteners and diet soda, including fat loss, obesity, insulin, diabetes and more, to give you the full picture, so you can unfollow the fear-mongering fitfluencers and rely instead on evidence to make the best decision for your goals.
- 2:08Philip Pape: Dustin Dwayne, welcome to the show.
- 2:11Philip Pape: My friends, thank you, thank you.
- 2:13Dwayne Ulrich: Glad to be here, man.
- 2:14Dwayne Ulrich: Glad to be here, it's an honor.
- 2:16Philip Pape: So I actually want to start with Dwayne, as the every man on BuzzAid Break the ice dude.
- 2:38Dwayne Ulrich: Just get it out of your system, okay, and Dustin's ego is going to be just fine here.
- 2:40Dwayne Ulrich: So I think I think so.
- 2:40Dwayne Ulrich: Here's my question for you, super simple what are the some of the scary things that dive off into the ingredients and what the sweeteners were?
- 2:47Dwayne Ulrich: It kind of freaks me out a little bit.
- 2:48Dwayne Ulrich: The only thing that and my interest in diet sodas came to me when I heard about I believe it was like I think maybe the army or something that guys really wanted a lot of diet Coke.
- 3:00Dwayne Ulrich: Diet Coke was one of the favorite things that they had.
- 3:03Dwayne Ulrich: So you know the US shipped diet Coke over to to them on these big pallets but they sat outside you know they're in like, I guess, in Iraq and heat on these Diet Cokes and these guys were drinking these Cokes but they'd been sitting out in the heat and they started getting lethargic and sleepy and I'm like that doesn't sound right to me.
- 3:21Dwayne Ulrich: So that's when I started taking a deep dive off into what the sweeteners were made of and what they look like.
- 3:28Dwayne Ulrich: Just listening to chemical contents or maybe about which we're not going to really talk about today, but chemical contents and how they're made kind of freaked me out a little bit.
- 3:39Dwayne Ulrich: It's weird.
- 3:41Philip Pape: Yeah, yeah, I would agree, man.
- 3:43Philip Pape: You know we've heard for years like the fewer ingredients the better, or if it's made in a lab, steer clear.
- 3:49Philip Pape: Or if you can't pronounce the ingredient, don't eat it.
- 3:52Philip Pape: There's, who is that on instagram.
- 3:53Philip Pape: She's hilarious, the nutrition, oh, you guys might know who she is.
- 3:56Philip Pape: She will like talk about a food that has all these chemicals and then she'll reveal that it's a banana you know, she'll say like there's all these chemicals and it's actually a banana I can't remember the name, uh gosh.
- 4:07Philip Pape: Yeah, I know you're talking about yeah, like a dietician, pharmacist, whatever, yeah.
- 4:11Philip Pape: And then the diet coke in the army thing.
- 4:12Philip Pape: I hadn't heard that.
- 4:13Philip Pape: What would you say today?
- 4:14Philip Pape: So do you drink it today, duane?
- 4:16Philip Pape: Do you drink diet soda?
- 4:17Dwayne Ulrich: no, no, not really because it scares me or anything.
- 4:20Dwayne Ulrich: But okay, man, I just don't like the taste.
- 4:22Philip Pape: You you don't like the taste, kind of chemically to you.
- 4:24Dwayne Ulrich: Well, I just want to say I need to be full disclosure.
- 4:27Dwayne Ulrich: I drink almost no soft drinks Okay cool.
- 4:31Dwayne Ulrich: I don't like the taste of the diet cokes.
- 4:36Dwayne Ulrich: I don't drink a lot of the diet drinks at all, never have and the content of sugar and other soft drinks.
- 4:43Dwayne Ulrich: It just doesn't fit my nutrition plan.
- 4:46Philip Pape: Sure, yeah.
- 4:46Philip Pape: So perfectly valid reason.
- 4:48Philip Pape: You don't like it.
- 4:48Philip Pape: It doesn't fit for you.
- 4:49Philip Pape: Yeah, love it.
- 4:50Philip Pape: Dustin, now, if diet soda kills you, why are you comfortable drinking it right now?
- 4:55Philip Pape: And what are you drinking?
- 4:58Dustin Lambert: Yeah, that is a good question, there we go.
- 5:03Dwayne Ulrich: Oh man Wait a minute.
- 5:05Dustin Lambert: He's got the classic the silver can, the classic I have the silver can, although I do think that the that dr pepper zero probably tastes the closest to the real thing.
- 5:15Dustin Lambert: However, where I have currently moved to like, a 12 pack of something is insanely expensive.
- 5:23Dustin Lambert: So buying a 24 packpack of Diet Coke so that's the only reason I have Diet Coke is just because of the price, but I do like the Dr Pepper Zero's best.
- 5:32Philip Pape: It is one of the most profitable products on the market.
- 5:35Philip Pape: I mean, you think they're just adding a tiny bit of, they're squirting in this tiny bit of syrup into water and they're basically selling water, right?
- 5:41Philip Pape: So again why am I not dead?
- 5:44Philip Pape: Yeah, why are you not dead?
- 5:45Philip Pape: I mean, we know how awful this stuff is.
- 5:47Philip Pape: Man, what are you doing yourself?
- 5:48Philip Pape: I?
- 5:49Dustin Lambert: guess.
- 5:49Dustin Lambert: Um, I don't know, maybe I'm a superhero.
- 5:52Philip Pape: Yeah, I mean, you are right so your, your gut, just like, just like churns that stuff into gold and you're good, right, pretty much.
- 6:03Dustin Lambert: Pretty much, yes.
- 6:03Dustin Lambert: And then, um, you know, the rest of it is excreted in urine.
- 6:07Dustin Lambert: Through excellence, so through excellence.
- 6:10Philip Pape: Okay, got to bottle that up, all right, so all right.
- 6:15Philip Pape: And also quasi seriousness.
- 6:16Philip Pape: We don't have to get all serious, can the premise of this, this episode and people are looking at the title, thinking diet soda is good for you.
- 6:22Philip Pape: It sounds like clickbait.
- 6:23Philip Pape: They're going to turn it around.
- 6:25Philip Pape: It's going to be this myth that we're breaking, like no, of course it's terrible for you or it can't be good for you.
- 6:29Philip Pape: Can it be good for you?
- 6:31Philip Pape: Like, let's start there and then we can break into the details.
- 6:35Dustin Lambert: Yep, so can it be good for you?
- 6:36Dustin Lambert: I think that the answer is yes.
- 6:50Dustin Lambert: It's kind of a weird position to defend here, but yeah, so I'm definitely up for the challenge, looking into it and so just to caveat, the entire podcast here.
- 6:54Dustin Lambert: I don't think it's the best thing that you could be drinking, but I'm going to be the lawyer for diet soda here today and I'm going to make the case that it can be particularly good for you, especially in certain circumstances.
- 7:08Dustin Lambert: So, context matters is what you're saying.
- 7:09Dustin Lambert: Context definitely matters, yeah.
- 7:12Philip Pape: Okay, how would you put it compared to alcohol, on the spectrum of beverages that are, quote unquote, good for you in general or depending on context?
- 7:22Dustin Lambert: On a scale of one to 10, it's probably a 12.
- 7:25Dustin Lambert: Better than alcohol, all right.
- 7:29Philip Pape: Okay, just lay in the relative things for people, because everybody loves to drink alcohol.
- 7:36Dustin Lambert: Yeah, I was going to say so that might jump into the cancer concerns right away.
- 7:41Dustin Lambert: So there are concerns for cancer regarding this stuff.
- 7:45Dustin Lambert: Probably the one sweetener that most people are familiar with would be aspartame, and that was recently added to the IARC list of carcinogens.
- 7:55Dustin Lambert: Now it's in the category of 2B, as in Bravo, which is a probable carcinogen, and it's in there with other things like pumping gas in your car, asian pickled vegetables, like a whole bunch of stuff.
- 8:06Dustin Lambert: And it's in there with other things like pumping gas in your car, asian pickled vegetables, like a whole bunch of stuff.
- 8:08Dustin Lambert: And it's hard to argue against the word probable, like is is stuff probably carcinogen?
- 8:13Dustin Lambert: Yeah, probably.
- 8:15Dustin Lambert: Alcohol, on the other hand, is a definite known carcinogen.
- 8:21Dustin Lambert: I believe that's class one class one.
- 8:22Dustin Lambert: I could be wrong.
- 8:23Dustin Lambert: So there's class one, class two a, class two B, and then you have class three, which is just not at all.
- 8:29Dustin Lambert: Uh, so alcohol is, I believe it's a class one carcinogen.
- 8:32Dustin Lambert: So, on the basis of you know whether it causes cancer or not, like should you drink diet soda instead of an alcoholic beverage?
- 8:40Dustin Lambert: Yeah, absolutely yes.
- 8:45Philip Pape: And that's a.
- 8:46Philip Pape: That's a great point.
- 8:46Philip Pape: Right there I think we're going to hit on throughout the show.
- 8:47Philip Pape: A lot of this is relative.
- 8:49Philip Pape: It really is relative.
- 8:51Philip Pape: I was on a show recently with and I'm not going to name names a very established nutrition coach who was asking me about some of these corner cases and things and I said you know, in a flexible diet, in context, these things are okay in small amounts, no big deal If it works for you.
- 9:06Philip Pape: What I want to do is take somebody from a 60% ultra-processed standard American diet with probably three cans of regular Coke, to something better than that, at least as step one, and then continue down that line.
- 9:18Philip Pape: So this kind of all or nothing like we need to eat clean, we need to cut everything out.
- 9:22Philip Pape: How dare you tell your clients that they can drink diet soda?
- 9:25Philip Pape: I think it's self-righteous at best and then it's unhelpful at worst.
- 9:32Philip Pape: So if someone says okay, why, if there's a probability right in quotes of it being cancers?
- 9:40Philip Pape: Why just be safe?
- 9:41Philip Pape: Better safe than sorry?
- 9:42Philip Pape: Why not just avoid it completely because of that answer?
- 9:45Dustin Lambert: is why just be safe?
- 9:46Dustin Lambert: Better safe than sorry.
- 9:47Dustin Lambert: Why not just avoid it completely because of that?
- 9:49Dustin Lambert: Yeah, you could make that argument and, again, context matters.
- 9:51Dustin Lambert: So it really depends on where you're starting from.
- 9:53Dustin Lambert: So, like you said, you want to take somebody from an ultra-processed diet, where maybe they are consuming sugar-sweetened sodas or other sugar-sweetened beverages, and we want to gradually, over time, get them to something that's more whole food, single ingredient.
- 10:12Dustin Lambert: You're consuming water, tea, stuff like that, so using it throughout that process and then even during fat loss phases.
- 10:21Dustin Lambert: For if you're periodizing your nutrition plan, which you should be, it can be quite helpful in those cases, formalizing this logically wise though to make that argument.
- 10:34Dustin Lambert: Well, if it's probably carcinogenic, why don't we just avoid all the things on the probable carcinogen?
- 10:40Dustin Lambert: Stop driving your car.
- 10:40Dustin Lambert: Stop wearing clothes that have dye in them.
- 10:41Dustin Lambert: Using cell phones?
- 10:41Dustin Lambert: Yeah, stop driving your car.
- 10:42Dustin Lambert: Stop wearing clothes that have dye in them.
- 10:44Dustin Lambert: You know like.
- 10:45Dustin Lambert: Using cell phones.
- 10:46Dustin Lambert: Yeah, stop using cell phones.
- 10:48Philip Pape: Using cell phones or being in the sun.
- 10:50Philip Pape: Let's let's be like yep, yep, right, going out in the sun.
- 10:53Philip Pape: So, dwayne, what are your thoughts on, from just again, the everyday guy nutrition plan, thinking about where you've come over the years, a lot of it with, with coach Lambie's guidance actually, is there something that you continue to enjoy?
- 11:06Philip Pape: That's like a little bit of a vice, where it doesn't matter because what you do today in context is significant improvement from where you were before.
- 11:15Dwayne Ulrich: Man.
- 11:16Dwayne Ulrich: So I don't know if that's a fair question in this context, because my vice is ice cream, so let's stick to soft drinks.
- 11:25Philip Pape: Well, what about all the ingredients in ice cream?
- 11:27Philip Pape: Well, that's another podcast.
- 11:32Dwayne Ulrich: No, but you know, just for me it's like I've tried to like diet drinks and I can drink maybe half of a Coca-Cola or half of a Dr Pepper.
- 11:43Dwayne Ulrich: Maybe Just after two or three or four sips of it I'm done.
- 11:46Dwayne Ulrich: But I just wanted to add on to something you guys were talking about, especially in the aspartame thing.
- 11:50Dwayne Ulrich: I did some research with Coach Lamb and we did a podcast on neotame and a while back we did a whole big old podcast on sweeteners and on the aspartame thing.
- 12:03Dwayne Ulrich: So yeah, it's a known carcinogen but I mean, you'd have to, you have to like consume like 80 something for 150 pound person.
- 12:11Dwayne Ulrich: You'd have to consume like 80 packets or 17 or 18, you know diet drinks in a day to like even start to be considerate, concerned about it.
- 12:21Dwayne Ulrich: So it's, it's like the thing you guys were just saying don't go outside, you know, don't breathe air.
- 12:26Dwayne Ulrich: So as much as I would like to say coming into this podcast, as much as I'd like to say that, oh, yeah, yeah, diet drinks are bad for you.
- 12:34Dwayne Ulrich: Diet drinks are bad for you.
- 12:35Dwayne Ulrich: I think that there's a component of consuming diet drinks that can maybe turn against you.
- 12:41Dwayne Ulrich: But man, I just I can't find a, I can't find a solid reason to say no, you know, or?
- 12:48Dwayne Ulrich: that it's bad, I can't.
- 12:50Philip Pape: Yeah, and we'll.
- 12:51Philip Pape: I know what you're alluding to.
- 12:52Philip Pape: We'll dive into some of the arguments people make against it.
- 12:55Philip Pape: Besides, the artificial sweeteners, we'll definitely go there, but before we get to that, I just want to kind of close out the topic here on, maybe, maybe from Dustin's standpoint as the expert here, having looked at a lot of these and talked about them a lot on his podcast the different sweeteners we have aspartame, we have sucralose, we have stevia, which is not artificial, technically right, and we have neotame, which you guys talked about.
- 13:16Philip Pape: What are the differences?
- 13:18Philip Pape: What is the history and composition of those that we need to be aware of as we make these decisions?
- 13:24Dustin Lambert: that we need to be aware of as we make these decisions.
- 13:26Dustin Lambert: In the grand scheme of things, I don't think we need to be aware of composition and how they're made and stuff.
- 13:32Dustin Lambert: Yeah, so we have different sweeteners.
- 13:33Dustin Lambert: We have some that are natural.
- 13:33Dustin Lambert: We have some that are synthetic Aspartame I think I probably could make a good case that aspartame is about as unnatural as cheese is because, quite frankly, it's just two amino acids that are bonded together through a process of fermentation.
- 13:50Dustin Lambert: Now it, like it, looks really scary when you look at pictures of the vats and everything and how fermentation is done.
- 13:56Dustin Lambert: However, when you look at how butter is made today and how cheese is made today, uh, you know it don't get me started on prosciutto, man, yeah so you know, like, yeah, so the history of most of these things.
- 14:15Dustin Lambert: As far as, like, maybe stevia and some other stuff, you can go down to the hardware store, like closer home depot or something, and buy a stevia plant right and you you can touch, touch the leaves or taste leaves and they're sweet.
- 14:25Dustin Lambert: So the process of getting sweeteners from plant sources and stuff is just kind of like the same as tea.
- 14:31Dustin Lambert: You kind of boil them in water, boil the leaves or whatever in water, and then through a process of distillation you remove the water from that and you're left with the sweetener Synthetic sweeteners.
- 14:43Dustin Lambert: On the other hand, some of them are made from natural chemicals and some are from man-made natural chemicals.
- 14:51Dustin Lambert: Some of the processes can be scary to think about.
- 14:56Dustin Lambert: In the grand scheme of things, knowing what they're made of or how they're made, I don't think is important, but knowing the upper limits, as Duane alluded to.
- 15:05Dustin Lambert: So we have ADIs on these things.
- 15:07Dustin Lambert: That's the advisable daily intake and that is set really conservatively low from what is known as the no observable adverse effect level.
- 15:19Dustin Lambert: It's usually 100 times lower than that and that usually comes from rodent studies where we give rodents tons and tons and tons of this stuff until we start to see that bad things happen to them, right, and so we say okay, at this amount, which is usually like a milligram per kilogram amount.
- 15:38Dustin Lambert: Per kilogram amount.
- 15:39Dustin Lambert: They'll usually bring that down a hundred fold to give us our adi.
- 15:45Dustin Lambert: So it it could be the case for some of them, um, like sucralose and saccharin, those the adis on those are are a little bit lower.
- 15:56Dustin Lambert: So it might be like five diet sodas a day versus something like aspartame, which is like 17, where you're reaching the ADI.
- 16:07Dustin Lambert: So you do run the possibility of reaching that upper limit where you may start to see some bad things happen.
- 16:10Dustin Lambert: But I think that's the thing to be concerned with what contains?
- 16:14Philip Pape: sucralose.
- 16:16Dustin Lambert: Just tell it so the listener is aware just just remind, just tell it so the listeners aware.
- 16:25Dwayne Ulrich: Um yeah, let me see so sucralose is known as splenda, so anything that has splenda in it.
- 16:27Philip Pape: Yeah, yeah, splenda, splenda yeah, yeah, and I believe most, most like typical diet.
- 16:30Dustin Lambert: Sodas have aspartame, but they also have combinations yeah, ace k would be the other one, or acyl sulfane potassium aculfame potassium.
- 16:39Philip Pape: Is that in the same boat as Splenda or is that more like aspartame in terms of the toxicity level?
- 16:44Dustin Lambert: Well, toxicity, yeah, so it's more like aspartame.
- 16:47Dustin Lambert: It is really a natural thing.
- 16:50Dustin Lambert: So an interesting little tidbit about Ace K is Ace K can actually be used to detect how much urine is in pools, because we don't metabolize it.
- 17:00Dustin Lambert: So every bit of it you excrete, like 99.99999% of the acyl sulfate, and so they've actually done some studies, and an Olympic-sized swimming pool on average contains about 70 gallons of urine.
- 17:18Stephanie: So okay, All right.
- 17:21Philip Pape: Hey, I'm glad you brought the Olympics into this.
- 17:22Philip Pape: The transcript will have SEO, but that point about how much is absorbed metabolized is important as well.
- 17:32Philip Pape: You guys did that episode on neotame.
- 17:33Philip Pape: Thank you for doing that, because that's been coming up more often and that's one of the points you made was the level of absorption is so tiny, you have to account for that yeah.
- 17:44Philip Pape: So these are important.
- 17:44Philip Pape: All right, let's move on to Okay.
- 17:46Philip Pape: So I think we've established that there's a certain level that is far beyond what a typical human is going to consume, and even if it is five or six cans a day, maybe that's in excess for any particular thing.
- 17:57Philip Pape: Anyway, for someone.
- 17:59Philip Pape: I'm guessing right.
- 17:59Philip Pape: What about the evidence on?
- 18:01Philip Pape: Let's go to the next thing body weight, weight management, because we hear two sides of the equation.
- 18:07Philip Pape: We hear, on one hand, these are zero calorie beverages, so of course you're not consuming any calories, so that's a benefit for for intake.
- 18:15Philip Pape: And you know, you feel something, you put something in your stomach, whether it's water, diet, soda doesn't have calories.
- 18:20Philip Pape: Maybe that helps with weight management.
- 18:21Philip Pape: On the other hand, all these claims about insulin being spiked and your sweet tooth is triggered, so now you're going to seek out other foods.
- 18:31Philip Pape: Lay it out.
- 18:32Philip Pape: What does the evidence say on all of this?
- 18:34Philip Pape: And maybe we can break it down and go one by one, starting with just the weight management.
- 18:39Dustin Lambert: Yeah, so on the weight management aspect of it, which kind of ties into whether or not it causes you to consume more sweets or more food in general, those are kind of tied together.
- 18:52Dustin Lambert: So what we're looking at is a discrepancy between experimental trials so people wouldn't know this as RCTs or randomized control trials, something like that and then what we see in epidemiology In randomized control trials, when we take people in and we put them in an experiment and we say, okay, we're going to randomize you guys, this group is going to get water, this group is going to get diet soda and we see what happens.
- 19:18Dustin Lambert: People lose weight and we have trials as long as a year, going on a year long here.
- 19:25Dustin Lambert: Let me see if I can find one.
- 19:27Dustin Lambert: Yeah, so we have one titled non-nutritive sweetened beverages versus water after a 52-week weight management program, a randomized control trial.
- 19:40Dustin Lambert: This is by Joanne Harold and colleagues trial.
- 19:42Dustin Lambert: This is by Joanne Harold and colleagues, released in the Journal of Obesity in 2024.
- 19:44Dustin Lambert: So very recent stuff, yeah.
- 19:45Dustin Lambert: So when we put people through these trials where we're actually randomizing them to one group or the other and we're going to replace sugar-sweetened beverages with either an artificially sweetened beverage or some other beverage normally it's water, we see weight loss.
- 19:58Dustin Lambert: We also see better adherence to weight management, weight loss management right.
- 20:04Dustin Lambert: So people tend to lose more weight in the artificially sweetened beverage trial versus water, and they also are able to maintain more weight loss than the water arm.
- 20:17Dustin Lambert: When we look into epidemiology, what we see is that higher rates of adiposity, obesity, overweight, bmi all that stuff tends to correlate with higher intakes of artificially sweetened beverages, diet sodas We'll just use diet sodas to make everything easier.
- 20:34Dustin Lambert: And so what a lot of the fear mongers, as you alluded to in the beginning.
- 20:40Dustin Lambert: What a lot of them do is they will take the correlation, the association from the epidemiology and just kind of run with it.
- 20:47Dustin Lambert: I say that's the results.
- 20:48Dustin Lambert: Here it is, but we have a discrepancy between the two, and it doesn't exist in every prospective cohort.
- 20:56Dustin Lambert: So we're talking about prospective cohorts here, but a lot of them do.
- 20:59Dustin Lambert: So we have to explain why, we have to account for why this discrepancy exists, and so the reason for that is that in these prospective cohorts, a lot of times what we're missing is a temporal component.
- 21:11Dustin Lambert: So we want to know if X came before Y or if Y became before X.
- 21:18Dustin Lambert: So did people start drinking diet soda before they became overweight and obese?
- 21:22Dustin Lambert: Or does being overweight and obese necessarily lead to people consuming more artificially sweetened beverages or diet sodas in an attempt to gain weight loss or to maintain some amount of weight loss?
- 21:36Dustin Lambert: There are other confounding factors.
- 21:39Dustin Lambert: I hate to use the word confounding, I'd rather use the word mediating or moderating.
- 21:43Dustin Lambert: There's other things like family history of obesity, all this stuff, and when we look at the cohorts and we take the ones that we actually have data for that we can actually make those adjustments right.
- 21:55Dustin Lambert: So reverse causality is what we're looking at.
- 21:57Dustin Lambert: Did diet soda cause obesity or is obesity causing the consumption of diet soda?
- 22:02Dustin Lambert: That would be reverse causality, and we adjust for all of these things.
- 22:05Dustin Lambert: What we find then, is that that association that we're looking at actually goes away.
- 22:12Dustin Lambert: Good meta-analysis here is by Lee and colleagues the relation of change or substitution of low and no-calorie student beverages with cardiometabolic outcomes, a systematic review and meta-analysis of prospective cohorts and what they did is they took some cohorts that had the data that they needed to make these adjustments and they adjusted for reverse causality and some of these other things that might confound those results, and what they found is that actually, sugar, sweet or diet sodas are associated with weight loss small amount and weight maintenance, not the other way around.
- 22:54Philip Pape: I love how you split those up too, because, on one hand, we're actually looking at causality, like you said, with the randomized controlled trials, and then, on the other hand, it's just a bunch of data that had been observed and now we have to link it together properly and have it in the right time-based direction.
- 23:08Philip Pape: Dwayne, what do you, what do you think about all this?
- 23:10Philip Pape: I've heard how you talk with Coach Lambie on your podcast.
- 23:14Philip Pape: It's it's so confusing, it's so overwhelming.
- 23:17Philip Pape: The average person is not going to be reading a bunch of papers, let alone reading one paper.
- 23:22Philip Pape: And they're trusting us, they're trusting people.
- 23:24Philip Pape: What are your thoughts on that, this or in general?
- 23:29Dwayne Ulrich: Well, just a couple of things.
- 23:31Dwayne Ulrich: One of the things that I looked at real quick.
- 23:32Dwayne Ulrich: I just want to put this out there before I forget about it but I looked at a study that came out of Harvard and so like, for some of the sweeteners and some of the soft drinks, particularly aspartame, had a tendency in animal trials to affect the animal's brain in such a way that it didn't know when to stop eating.
- 23:52Dwayne Ulrich: Now that sounds like I'm fighting for the other side.
- 23:56Dwayne Ulrich: I believe that what the data shows us, as Coach Lambie showed it, is that it can help you with the weight loss or at least maintain, and that seems to be the overwhelming deal there.
- 24:09Dwayne Ulrich: But anecdotally, I see people that in my own life just people that I know that they drink a lot of artificially sweetened soft drinks.
- 24:20Dwayne Ulrich: For them they maintain.
- 24:22Dwayne Ulrich: Most of the time they maintain.
- 24:24Dwayne Ulrich: I know people that are already obese that drink artificial soft drinks.
- 24:28Dwayne Ulrich: Do they get bigger?
- 24:29Dwayne Ulrich: Not over my experience, not for as long as I've known some of these people.
- 24:38Dwayne Ulrich: But I do believe there's a responsibility on the individual.
- 24:41Dwayne Ulrich: Going back to nutrition, because if you just drink that and think that's going to help you lose weight, that may not be really the case for you.
- 24:49Dwayne Ulrich: But by the same token, if you're tanking on soft drinks that are artificially sweetened, there's a possibility for you to eat more.
- 24:56Dwayne Ulrich: I see that as a thing, just anecdotally from what I know.
- 25:01Dwayne Ulrich: And then when I go look at things like the Harvard study, I'm like maybe there is some causality there.
- 25:08Dwayne Ulrich: It kind of helps you forget when you need to stop eating.
- 25:11Dwayne Ulrich: I do see that.
- 25:12Dwayne Ulrich: So what is it?
- 25:14Dwayne Ulrich: I can't find any reason to tell somebody you shouldn't drink that because you're just going to gain weight.
- 25:20Dwayne Ulrich: That doesn't make sense.
- 25:22Dwayne Ulrich: It's just not a sensical conversation or an argument.
- 25:26Dwayne Ulrich: And when you look at the data like Coach Lambie just went through, yeah, it doesn't really bear out.
- 25:31Dwayne Ulrich: I mean, yeah, there's a possibility that maybe it affects your brain and you just don't know when to stop eating.
- 25:36Dwayne Ulrich: I think that's an exception more than it is a rule.
- 25:41Philip Pape: Does that make sense?
- 25:42Philip Pape: Yeah, and it makes total sense.
- 25:44Philip Pape: And you're hitting on the nuance here.
- 25:45Philip Pape: There's so much nuance.
- 25:46Philip Pape: What comes to mind for me is if I had a client who we're going to do fat loss, I'm not going to prescribe them Diet Coke, but if they were drinking regular Coke and said I really crave these things, I can't help, I drink them all the time, we'd have the discussion Hmm, have you tried Diet Coke?
- 26:05Philip Pape: Like, why don't we try that?
- 26:07Philip Pape: Like let's experiment and see, right.
- 26:10Philip Pape: And that's one thing that comes to mind.
- 26:12Philip Pape: Another is I think we're trying to add the nuance so that people don't think like Diet Coke absolutely causes weight gain, because we see that that's not the case either.
- 26:21Dwayne Ulrich: Correct.
- 26:22Philip Pape: And things are personalized.
- 26:23Philip Pape: And you're right, who knows?
- 26:27Philip Pape: With the context of these individuals?
- 26:28Philip Pape: I grew up in households that there was a lot of Diet Coke consumption and you're right, I see it in obese populations.
- 26:31Philip Pape: There's a lot of that and, like Dustin said, there's confounding, mitigating factors going on and maybe they just incorporated it at some point, hoping to lose weight, but nothing else changed.
- 26:41Philip Pape: And now you're like, okay, what are we really looking at here?
- 26:44Philip Pape: So the data is important, but also the individual.
- 26:46Philip Pape: You know history with this.
- 26:49Dwayne Ulrich: Right.
- 26:50Philip Pape: Do you think, dustin, we cover the first piece right of?
- 26:53Philip Pape: It probably doesn't cause weight gain and it probably is a helpful tool for a lot of people, especially when substituting something with calories.
- 27:00Philip Pape: Just okay, good.
- 27:03Stephanie: We're in agreement, do you?
- 27:03Dustin Lambert: want me to elaborate on that.
- 27:05Dustin Lambert: No, no, no.
- 27:05Philip Pape: That was like.
- 27:06Philip Pape: I'm like blabbering, I'm rambling on here.
- 27:09Stephanie: The most value that I got from this was the fact that I had someone that I could talk to about anything and that there was going to be no judgment.
- 27:18Stephanie: It was just well, here are your goals, here's the best way that you're going to achieve it, and then let's work together to help you feel inspired and motivated to do that and there's a lot of people out there trying to be coaches and not all of them have done the work and also just be a genuine person that is positive and coming from the heart in terms of wanting to help, and Philip really embodied all of those qualities.
- 27:45Stephanie: I would recommend him to just about anyone that's looking to achieve goals in that realm of their nutrition and building new habits.
- 27:54Philip Pape: Let's go to the next thing, which is enjoyment.
- 27:56Philip Pape: So what about the fact that it tastes sweet drink enjoyment?
- 27:59Philip Pape: It has carbonation, all of that stuff.
- 28:02Philip Pape: Where does that come in?
- 28:03Dustin Lambert: Yeah, so it does taste sweet.
- 28:06Dustin Lambert: So all of the sweeteners are some multiple thousands of times sweeter than sugar, which allows us to use a lot less of them.
- 28:12Dustin Lambert: As Dwayne alluded to, he doesn't really like the taste of it.
- 28:16Dustin Lambert: So I'm with you.
- 28:19Dustin Lambert: My clients are a little bit different than yours, where I'm dealing with people who are knocking on the doorstep of diabetes and in those cases I am often am prescribing it because many people are drinking, you know, six to 10 sugar sweetened sodas a day, and it's kind like well, hey, listen, like I get it.
- 28:41Dustin Lambert: There's more to this than just the food, right, there's a genetic aspect to it.
- 28:45Dustin Lambert: There's also a psychological aspect to all of this stuff and it's like I, I, I understand it.
- 28:50Dustin Lambert: Uh, so let's start maneuvering our way into, you know, instead of six to eight regular sodas a day to six to eight diet sodas a day, and then again the time.
- 29:01Dustin Lambert: You know, I tell everybody like it doesn't matter where we get in the next six months, what's important is where we get in the next six years.
- 29:06Dustin Lambert: So even if we're consuming a 12 pack of diet soda a day right now, right, as long as there's an exit strategy to get to that point, we need to be there.
- 29:17Dustin Lambert: It does, you know, handle the sweet tooth.
- 29:19Dustin Lambert: When I go through fat loss phases and I'm craving sweet things myself, a diet soda often does alleviate whatever that craving is.
- 29:28Dustin Lambert: You know, the carbonation in it also helps.
- 29:31Dustin Lambert: I think people feel full and that can help during weight loss periods or fat loss phases.
- 29:36Dustin Lambert: You know, you're not always going to outrun the ghrelin monster forever.
- 29:41Dustin Lambert: It's going to catch up with you at some point.
- 29:42Dustin Lambert: So again, nuance to all of this stuff.
- 29:45Dustin Lambert: But yeah, it can cure.
- 29:47Dustin Lambert: Not cure, but it can help alleviate sweet tooth cravings.
- 29:52Dustin Lambert: It can help with that psychological aspect of you.
- 29:57Dustin Lambert: Know, I've been drinking soda for a while now and I, I love them.
- 30:01Dustin Lambert: I don't want to give them up, uh.
- 30:02Dustin Lambert: So okay, well, let's just let's swap over to this that reduces the amount of sugar intake that that my clients are seeing, which brings their fasting glucose down, their hba1c down, all that stuff.
- 30:13Dustin Lambert: So yeah, for the everyday person, um, you know, if you're, if you're looking to maybe reduce intake of certain foods that are sweet or whatever the case may be, diet, soda certainly can help in that aspect.
- 30:29Philip Pape: Yeah, I agree.
- 30:29Philip Pape: I'm actually in fat loss again now and I typically will have a can of diet soda almost once every day during fat loss, just in the afternoon, like I'm doing right now, because it it fits in that window, it hydrates me and it tastes good.
- 30:43Philip Pape: I mean, I don't see anything wrong with it and that's kind of what we're here to to give people that peace of mind of it's okay, it's okay, it's like.
- 30:51Philip Pape: You know what do you think, duane?
- 30:53Dwayne Ulrich: yeah, oh I, I completely agree.
- 30:55Dwayne Ulrich: It's like um, yeah, I for one thing.
- 30:58Dwayne Ulrich: It's like the long term is is thinking it in short term.
- 31:01Dwayne Ulrich: You have to think in a longer term.
- 31:03Dwayne Ulrich: We all like to change things right away.
- 31:05Dwayne Ulrich: We're in a hurry, I've got to have it now.
- 31:06Dwayne Ulrich: I've got to change right now.
- 31:07Dwayne Ulrich: I've got to lose all this weight right now.
- 31:08Dwayne Ulrich: I've got to stop being a diabetic today.
- 31:10Dwayne Ulrich: It's a process.
- 31:12Dwayne Ulrich: It's a process compared to sugar-sweetened soft drinks, what they call SSB, sugar-sweetened beverages.
- 31:22Dwayne Ulrich: Man, the amount of sugar in a regular soda water, man, I'm just kind of sorry I started reading that, but it's staggering.
- 31:36Philip Pape: So, yeah, I think the artificially sweetened soft drinks, it's a definite plus, it's a definite plus, and I'll tell you a few times you mentioned the amount of sugar A couple times.
- 31:44Philip Pape: I might have gone and asked for a fountain soda at a place and they gave me the sweetened version of it instead of the diet, and usually I can tell that they're really good.
- 31:54Philip Pape: With the Coke Zeros and everything, it almost tastes the same.
- 31:56Philip Pape: So I'm drinking it and I'm getting that kind of sweet smacking kind of taste, but I just finish it thinking in my head like no, no, they gave me the diet.
- 32:04Philip Pape: And then I come to find they didn't and I'm like, okay, that's 300 calories right there, like I just make sure to track it sometimes you can almost feel it feels like fur on your teeth.
- 32:13Dwayne Ulrich: What was that?
- 32:15Philip Pape: yeah, of course like you said, some people don't like the artificial sweetener and you don't have to drink this stuff.
- 32:19Philip Pape: We're not saying it and there could be haters and trolls on this.
- 32:22Philip Pape: In fact, I welcome you guys who are like how dare you tell us to drink any diet soda, eat any seed oils, blah, blah, blah.
- 32:28Philip Pape: We love it.
- 32:29Philip Pape: Bring it on.
- 32:29Philip Pape: So, dustin, did we address the part about whether it causes you to eat more?
- 32:35Philip Pape: I mean, we address that studies show it doesn't cause weight gain, but what about this idea that it both spikes your blood sugar but and or causes you to eat more?
- 32:44Philip Pape: Yeah, okay, so there are two different things.
- 32:47Philip Pape: Let's start with the eat more thing.
- 32:49Dustin Lambert: Yeah, the eat more thing.
- 32:50Dustin Lambert: Okay, um, so, yeah.
- 32:52Dustin Lambert: So if we're looking at the epidemiology and we would see that, um, higher rates of of overweight and obesity correlate with higher consumption of diet sodas, and then we also might just observe people in our own lives who have been overweight their whole life and they always drink diet soda and we're like, well, that's not helping out at all.
- 33:11Dustin Lambert: So I can see where that idea comes from, comes from.
- 33:20Dustin Lambert: And then, as Duane alluded to, we certainly do have rodent studies where they give them artificial sweeteners and it leads to an increase in spontaneous consumption of calories, hitting on the rodent stuff.
- 33:28Dustin Lambert: And this goes into gut microbiome research and cancer research as well.
- 33:33Dustin Lambert: So there have been several papers.
- 33:35Dustin Lambert: I brought up a couple of them in our artificial food coloring episodes and then there was one that came out very, very recently in dealing with cancer.
- 33:47Dustin Lambert: I believe I don't have that one pulled up, but Dr Allo, dr Muhammad Allo, he brought that up on Twitter what we see from rodent research regarding translation to human outcomes.
- 34:00Dustin Lambert: So if we just look at the amount of rodent research where we might be trying to develop a drug or something to treat human disease, the amount of drugs that we'd start testing in rodents and even psychological outcomes and even cancer outcomes.
- 34:18Dustin Lambert: That actually makes it to first phase clinical human trials and then even less once we get to FDA.
- 34:26Dustin Lambert: Approval of things translates to about 5%.
- 34:29Dustin Lambert: So 95% of the rodent research that's out there does not translate to human outcomes, okay, okay.
- 34:37Dustin Lambert: So if we have a rodent study that shows we give rodents this sweetener and it spontaneously increases their calorie consumption, we might look at a few things how much of it are they giving?
- 34:51Dustin Lambert: You know, what is the length of exposure that they're allowed to have, all these things.
- 34:56Dustin Lambert: But then the other aspect is that, well, it probably doesn't translate very well to human outcomes because we have human randomized control trials where we give people diet soda and they don't eat more, they eat less.
- 35:10Dustin Lambert: So just substituting and a lot of these trials that we're talking about.
- 35:14Dustin Lambert: We're talking about a substitution of two beverages a day, so two cans.
- 35:23Dustin Lambert: Substitution of two beverages a day, so two cans.
- 35:24Dustin Lambert: 12 ounce cans of soda per day is the is, uh, what most of these trials shoot for with a minimum of three sodas per week.
- 35:28Dustin Lambert: So even at a minimum of three sodas per week, we are seeing spontaneous weight loss.
- 35:34Dustin Lambert: So whatever is happening there as far as the impact that these might have on brain regulation or gut regulation is leading people to eat less.
- 35:46Dustin Lambert: It's not the other way around, right, because when we actually test it, what happens when we give people diet soda and we're actually measuring these outcomes?
- 35:53Dustin Lambert: People lose weight.
- 35:54Dustin Lambert: They don't gain weight.
- 35:56Philip Pape: So do you think it simply comes down to energy balance at the end of the day here and that there are no other aspects of the in our guts or gut?
- 36:05Philip Pape: So also all that?
- 36:23Dustin Lambert: stuff.
- 36:23Dustin Lambert: And then we also know that gut microbiota or um, what's the term?
- 36:28Dustin Lambert: I'm looking here for laura the um, no, the whole thing.
- 36:31Dustin Lambert: So I saw our entire digestive tract right.
- 36:34Dustin Lambert: So there's all stuff going on and we have a gut brain and we have drugs out now that stimulate hormones that are produced in response to things that happen in our gut and that signals our brain.
- 36:47Dustin Lambert: So I certainly think that there's something happening there.
- 36:51Dustin Lambert: We do know that there are changes that happen to certain microbiota or flora within our gut when we consume.
- 36:58Dustin Lambert: A lot of people take that as being negative.
- 37:00Dustin Lambert: However, when we look at the outcomes, I would have to say that those changes have to be a positive effect, because we're seeing the outcomes that we want to see.
- 37:11Dustin Lambert: We're seeing people lose weight, we're seeing lower fasting glucose numbers.
- 37:15Dustin Lambert: Long-term HbA1c comes down a little bit, but a lot of those trials just aren't long enough to notice a change there or they're not looking at it.
- 37:25Dustin Lambert: Yeah, so so is it?
- 37:26Dustin Lambert: Does it just come down to calories, like is it just that I'm replacing 150 calories with zero calories?
- 37:33Dustin Lambert: I don't think so, uh, because the amount of weight loss that we're seeing would lead us to believe a little bit more.
- 37:39Dustin Lambert: I think that whatever's happening to the changes in the gut and the changes whatever may be happening in response to that in the brain is spontaneously causing people to eat just a little bit less.
- 37:50Dustin Lambert: It's not huge, all right it's.
- 37:52Dustin Lambert: This isn't magical and it's not going to get.
- 37:55Dustin Lambert: It's not the staff of Moses here.
- 37:56Dustin Lambert: So yeah, but I think that there is something else to it.
- 38:00Philip Pape: That's an interesting one, cause we've now we're we're almost taking the benefit even that one step further.
- 38:04Philip Pape: The gut health thing is talked about more often now as as a negative and, like you said, maybe there's something else going on.
- 38:10Philip Pape: If we use the transitive property right, like if you do this and then on this side, it results in weight loss and we know gut health and cognitive function, whatever also affects that weight loss, beyond what energy balance would explain.
- 38:23Philip Pape: Therefore, the diet soda is doing something.
- 38:25Philip Pape: I mean I, I get that logic.
- 38:27Philip Pape: Yeah, we have the comparison to water.
- 38:29Dustin Lambert: So we have zero calorie versus zero calorie and in the diet soda arms, they lose more weight.
- 38:35Dustin Lambert: So there has to be something that's happening there that's causing just a little bit more of a calorie deficit, which we can only assume is people are eating less.
- 38:48Philip Pape: Could it be the satiety effects of it?
- 38:50Philip Pape: Sure, have they compared carbonated pure water as?
- 38:54Dustin Lambert: well to soda, yep, yep.
- 38:56Dustin Lambert: So when we compare the diet soda to the water arms, people are allowed to have carbonated beverages and a lot of these trials are free living trials.
- 39:05Dustin Lambert: It's not a metabolic ward study.
- 39:07Dustin Lambert: A lot of these are free living right, so people are just at home doing stuff.
- 39:11Dustin Lambert: So what happens when we give people diet soda and they're at home and they're not advised to try to lose weight and we're looking at a carbonated, artificially sweetened beverage?
- 39:23Dustin Lambert: And a lot of these are not just diet soda, but it's also the waters that you can get, the flavored and sweetened waters that are zero calorie, that are carbonated.
- 39:31Dustin Lambert: But in the water arms they also are allowed to have carbonated water.
- 39:35Dustin Lambert: So it's not just an effect of well, maybe this one has carbonation, this one's plain water.
- 39:39Dustin Lambert: There's something more there.
- 39:42Philip Pape: And could it be just psychological hunger?
- 39:44Philip Pape: Because I feel like even in my own personal experience, it takes away the craving.
- 39:50Philip Pape: It kind of rubs that itch and therefore you don't eat.
- 39:53Philip Pape: And it's as simple as that.
- 39:54Philip Pape: What do you think it could be?
- 39:55Philip Pape: Yeah, yeah, it's fascinating.
- 39:57Philip Pape: Well, whatever it is for an individual, they can they can look at the data and see what happens.
- 40:00Dwayne Ulrich: And so I agree, I agree with that.
- 40:03Dwayne Ulrich: I read some studies about, uh, the carbonated water also kind of having the same effect.
- 40:08Dwayne Ulrich: I agree there's something more about the diet soda as opposed to just carbonated water.
- 40:14Dwayne Ulrich: But carbonated water has a more, I think, a more intense effect than just plain water itself.
- 40:20Dwayne Ulrich: And I want to go back to the rodent thing I said earlier because I don't want people to misunderstand about, you know, certain sweeteners causing you know animal trials to where they didn't know when to stop eating.
- 40:31Dwayne Ulrich: The thing Coach Lambie said about when we're using rodent studies, a lot of times what they're pushing for is they're just pushing for the maximum amount.
- 40:42Dwayne Ulrich: When do we get an adverse effect?
- 40:45Dwayne Ulrich: So I think we were doing a study on neotame on our podcast.
- 40:47Dwayne Ulrich: You know when do we get an adverse effect?
- 40:49Dwayne Ulrich: So I think we were doing a study on neotame on our podcast, and so they gave the animal subject.
- 40:53Dwayne Ulrich: Like what, coach?
- 40:54Dwayne Ulrich: Was it 7,000 times what the normal would be?
- 40:58Dustin Lambert: That one was just a petri dish.
- 41:00Dwayne Ulrich: Oh well, petri dish.
- 41:01Dustin Lambert: Oh no, no, I just referenced stuff in the past that we looked at.
- 41:07Dwayne Ulrich: Yeah, but it's just massive.
- 41:07Dwayne Ulrich: But they give massive amounts to.
- 41:09Dwayne Ulrich: I mean, just look at the.
- 41:10Dwayne Ulrich: We talked earlier about aspartame.
- 41:12Dwayne Ulrich: Well, good lands, you've got to drink 17, 18 sodas before there's any adverse effects.
- 41:19Dwayne Ulrich: I don't want people to be misled.
- 41:22Dustin Lambert: Not even that.
- 41:22Dustin Lambert: That's just to reach the ADI.
- 41:24Dwayne Ulrich: Yeah and I don't want people to be misled by that that that's, oh my gosh, something bad's going to happen.
- 41:28Dwayne Ulrich: So there's obviously something happening in the gut biome that you know.
- 41:33Dwayne Ulrich: Something's happening down there.
- 41:35Philip Pape: I don't really know what it is, but I think it's effective the longevity guys pushing low protein based on rats and I just I drew the line there.
- 41:49Philip Pape: I'm like no, no, we're not doing that.
- 41:52Philip Pape: Okay, let's talk about insulin response.
- 41:56Philip Pape: Okay, I think that's the other one here right, cause you do talk about prescribing this for diabetics as a alternative to sweeters.
- 42:03Philip Pape: But let's take people who maybe weren't drinking diet soda at all.
- 42:06Philip Pape: Maybe in randomized controlled trials they've looked at this.
- 42:09Philip Pape: You add it in.
- 42:10Philip Pape: Does it affect your blood sugar?
- 42:14Dustin Lambert: Yes, it affects blood sugar.
- 42:15Dustin Lambert: So we can speak to the fear mongers because I think this is another criticism that people have about it is that, well, this thing is sweet, right, and when you taste it, your brain thinks it's receiving sugar, and that stimulates the production of insulin and that leads to insulin resistance.
- 42:37Dustin Lambert: Okay, so, not even just going into trials, but if we just logic this argument out here, okay, so let's just say, for the sake of argument, that that's happening right.
- 42:50Dustin Lambert: As soon as it hits your taste bud, your brain goes ah, there's sugar release, insulin.
- 42:54Dustin Lambert: Well, number one.
- 42:55Dustin Lambert: That's not how insulin is released.
- 42:57Dustin Lambert: Again, let's just say that it is all right.
- 43:01Dustin Lambert: So let's say that it's a big bolus of insulin, right.
- 43:04Dustin Lambert: So your brain thinks that you're getting whatever seven teaspoons of sugar, and so it signals to your pancreas to release the amount of insulin to dispose of seven teaspoons of sugar.
- 43:16Dustin Lambert: If I woke up first thing in the morning without eating anything and I drank this diet soda here and my pancreas released enough insulin to dispose of the amount of sugar that would be in a sugar-sweetened soda, I would go into hypoglycemic shock, right, it would induce vomiting, it would induce nausea, I would probably lose my vision and I would most likely become unconscious.
- 43:41Dustin Lambert: Now that's not happening because I haven't eaten anything today and I, this monster, and I am also drinking this Diet Coke, so that's not happening.
- 43:52Dustin Lambert: Okay, so it's not a large bolus of insulin.
- 43:54Dustin Lambert: Maybe it's a small one, right?
- 43:56Dustin Lambert: Maybe it's a little bit.
- 43:57Dustin Lambert: Okay, fine, let's say that that's happening.
- 44:01Dustin Lambert: If you are of the position which most of them are, that high blood sugar is bad and you need to reduce that, you should be having as little amount of stored glucose in your liver and your muscles and everything as glycogen as possible.
- 44:18Dustin Lambert: What would small amounts of insulin do?
- 44:22Dustin Lambert: If I just had this diet soda and I didn't eat anything and I had high blood sugar and I had fatty liver maybe and fatty liver can come from excess glycogen within the liver Well, these small amounts of liver would reduce my homeostatic blood sugar, my blood glucose level, fasting glucose levels, just a little bit, and that reduction would signal glucagon to tell my liver that blood sugar has come down.
- 44:50Dustin Lambert: Please release some glucose into the bloodstream to bring us back to homeostasis.
- 44:55Dustin Lambert: If I did that several times a day over the course of weeks and months, what I would end up with is a liver with lower glycogen stores and also lower glycogen stores in my muscle and also a lower fasting glucose level.
- 45:10Dustin Lambert: So if that were happening, I'm not really sure how you could make the case that that's a bad thing, right?
- 45:17Dustin Lambert: So that's one.
- 45:19Dustin Lambert: Number two it doesn't stimulate insulin.
- 45:21Dustin Lambert: Okay, so the way insulin is stimulated is that your pancreas has a large artery runs right through it and it pulls blood out of that artery to sense how much glucose is floating around in your bloodstream and that's how it knows how much insulin right, and also receives some signals from the liver.
- 45:40Dustin Lambert: The liver and the pancreas work together to keep blood sugar levels stable.
- 45:45Dustin Lambert: That's why type 1 diabetics have such issues.
- 45:47Dustin Lambert: Also type 2 diabetics, right, because at some point they start losing control of that thing and you no longer have homeostasis.
- 45:55Dustin Lambert: You start dipping into dangerously low levels or dangerously high levels.
- 45:59Dustin Lambert: People love social media.
- 46:01Dustin Lambert: There are tons and tons of videos of people out there wearing a CGM and will drink a diet soda and show you it does absolutely nothing.
- 46:08Dustin Lambert: It does nothing, so they don't stimulate insulin.
- 46:12Dustin Lambert: Now let me put the caveat.
- 46:13Dustin Lambert: Okay, so I will say as far as like an insulin resistance aspect goes, I have seen some stuff on sucralose that would give me pause in recommending that, right?
- 46:28Dustin Lambert: So that's the Splenda.
- 46:29Dustin Lambert: So yeah, I have seen some stuff.
- 46:31Dustin Lambert: So there is another guy on YouTube and he did a pretty good three or four week look into sucralose and looking at insulin resistance and there's something there that gives me pause.
- 46:42Dustin Lambert: I think maybe if you were to have a little bit of that, so one packet of it or something in your tea for lunch, probably not going to be a big deal, but that would be the only one.
- 46:51Philip Pape: All right, yeah, just want to put that to bed for people Again.
- 46:54Philip Pape: If you just look anecdotally and, like you said, logically follow it through, people aren't getting, you know, insulin shock, as if they just injected themselves on a regular basis Because guess what?
- 47:05Philip Pape: A lot of people are drinking them while they're fasting, so you would see this often.
- 47:09Philip Pape: So, man, we'll take care of those intermittent fasters right now.
- 47:15Dwayne Ulrich: Just feed them a bunch of diet soda.
- 47:16Philip Pape: Okay, so that's good.
- 47:17Philip Pape: So we're ticking off all the boxes here, I think.
- 47:20Philip Pape: And we sort of alluded to how it of course helps with weight management, it helps with diabetes.
- 47:24Philip Pape: Is there anything in the realm of cardiovascular disease stroke we wanted to cover?
- 47:28Philip Pape: I mean specifically because obviously those risks also come down in concert with these other risks coming down.
- 47:35Dustin Lambert: Yeah, those risks come down.
- 47:36Dustin Lambert: So if you substitute some sugar-sweetened sodas with artificially sweetened sodas, you're drinking diet sodas now and you managed to lose some weight.
- 47:44Dustin Lambert: Obviously you're dealing with fewer carbohydrates coming in.
- 47:47Dustin Lambert: That's going to have an effect on blood glucose.
- 47:49Dustin Lambert: Let's put all of that aside and look at where we have adjusted for weight loss and other things.
- 47:59Dustin Lambert: Do diet sodas have an impact in and of themselves on certain risk factors for cardiovascular disease, diabetes and stuff In terms of diabetes?
- 48:10Dustin Lambert: I don't think that in and of itself it has anything that really has to do with lowering your carbohydrate intake and also the weight loss.
- 48:16Dustin Lambert: Now there is an effect on blood pressure that's seen independent of weight loss, independent of anything else, and when we compare diet soda to water again, what we end up seeing is a reduction of about 2.5, about 2.6 millimeters of mercury systolic.
- 48:34Dustin Lambert: So that's the top number.
- 48:35Dustin Lambert: That's independent of weight loss alone.
- 48:38Dustin Lambert: We did an episode on coffee not too long ago and we saw kind of a similar effect there.
- 48:45Philip Pape: So hold on these.
- 48:46Philip Pape: Caffeine containing soda.
- 48:48Philip Pape: Caffeine containing soda yeah, okay, not diet, this is not with caffeine free.
- 48:53Dustin Lambert: Right, Not caffeine free.
- 48:54Dustin Lambert: Yeah, so it would be just low calorie, no calorie.
- 48:58Dustin Lambert: Sweetened beverages in general I'm just using the word diet soda to be the simple here right, so they may contain caffeine and they may not.
- 49:07Dustin Lambert: But overall, when meta-analyzed, what we see is that artificial sweetened beverages tend to lower blood pressure just a little bit more than water when we substitute sugar sweetened beverages.
- 49:19Dustin Lambert: So it's about two and a half millimeters of mercury systolic top number.
- 49:25Dustin Lambert: It's estimated by the American Heart Association that a three millimeter of mercury reduction in systolic blood pressure on an individual basis is clinically meaningful.
- 49:36Dustin Lambert: So on itself all alone it almost gets you to that clinically meaningful reduction.
- 49:44Dustin Lambert: Right, If you manage to lose weight now, you're in a clinically meaningful reduction.
- 49:48Dustin Lambert: So that reduces your risk of coronary heart disease and it also reduces your risk of stroke.
- 49:54Dustin Lambert: On a national level, on a population level, 5.5 millimeters of mercury, that would lead to a 15% reduction in coronary heart disease and a 27% reduction in stroke.
- 50:16Dustin Lambert: So that's at 5.5.
- 50:18Dustin Lambert: So if we do some quick math here, we go down to 2.5, 2.6, what we're looking at on a nationwide level would be somewhere around a 6% or 7% reduction in coronary heart disease incident, Not risk incidence of coronary heart disease and somewhere around a 12% reduction in stroke incidence.
- 50:36Dustin Lambert: So coronary heart disease, we're talking about stuff like heart attacks and other things like sudden heart failure, pectoral angina, all that stuff.
- 50:46Dustin Lambert: There's about 800,000 people who have heart attacks every year and there's about 800,000 people who have strokes every year.
- 50:54Dustin Lambert: What that results to if this were to be the case, if we could get a nationwide reduction of 2.5 millimeters of mercury systolic blood pressure, that would be about 40,000 fewer heart attacks every year and about 100,000 fewer strokes.
- 51:09Philip Pape: So, dwayne, you're going to start drinking diet soda now, right, not only do we say it's not bad for you, it's good for you, it's good for you.
- 51:16Philip Pape: We got some diet root beer in the fridge right now the root beer is caffeine free, so just make sure you pick the time of day you want it.
- 51:24Dwayne Ulrich: Oh, I drink my coffee.
- 51:25Dwayne Ulrich: I do drink coffee.
- 51:27Philip Pape: Yeah, yeah, ah, it's so fascinating.
- 51:28Philip Pape: Right With the blood pressure, is there a concurrent reduction in blood lipids like LDL?
- 51:35Philip Pape: Do they have data on that, because that's again another factor for CBD.
- 51:39Dustin Lambert: Yeah, so there is reduction in blood lipids.
- 51:42Dustin Lambert: I think that probably has more to do with the weight loss than anything.
- 51:45Philip Pape: Wow, crazy.
- 51:46Philip Pape: So yeah, seriously, we are delivering on the promise of this episode so far.
- 51:52Philip Pape: I think that there is a case that it can be good in some cases for certain people, in certain contexts.
- 51:57Philip Pape: I'm going to keep saying that.
- 51:58Philip Pape: Oh, speaking of coffee, you guys drink cryo brew.
- 52:00Philip Pape: You ever tried that?
- 52:01Philip Pape: It's a brewed coffee.
- 52:03Philip Pape: So I mean brewed chocolate.
- 52:06Dustin Lambert: It's brewed, chocolate brewed oh, that's my alley here.
- 52:09Philip Pape: Yes, yeah, check it out, attention, check it out.
- 52:11Philip Pape: So it's got almost no caffeine.
- 52:13Philip Pape: So for me it's like having coffee at night.
- 52:15Philip Pape: You know, I can have that cup of coffee at night again during fat loss.
- 52:18Philip Pape: It's kind of like diet soda it itches, the flavor and the craving and the having something in your mouth, but with the more um, the bitterness and like thickness of coffee, of a coffee.
- 52:28Philip Pape: Yeah, I'm a foodie, if you couldn't tell, I could.
- 52:30Philip Pape: So, speaking of so, where does caffeine fit into all this?
- 52:34Philip Pape: And that's why I alluded to it, because that's a strong factor, I imagine, depending on what you're studying.
- 52:40Dustin Lambert: Yeah, so the caffeine?
- 52:42Dustin Lambert: So you know caffeine levels vary between diet sodas.
- 52:45Dustin Lambert: So what I found between the diet soda stuff and the coffee stuff is that caffeine is a diuretic, so it will cause you to pee more.
- 52:54Dustin Lambert: However, diet sodas are 95% water.
- 52:58Dustin Lambert: We don't see dehydration happening from consumption of diet soda or coffee.
- 53:07Dustin Lambert: That's not happening, and so, despite caffeine being a diuretic, it just may be that you're drinking enough water along with it to counteract that effect.
- 53:15Dustin Lambert: Duane, did you look into the sodium excretion?
- 53:19Dwayne Ulrich: yeah, it's.
- 53:19Dwayne Ulrich: It's kind of.
- 53:20Dwayne Ulrich: It's kind of just um, and it's kind of like social media fodder, just like, uh, being dehydrated because you drink too much caffeine or you eat too much coffee.
- 53:29Dwayne Ulrich: The same thing with diet drinks.
- 53:32Dwayne Ulrich: It's just social media fodder.
- 53:36Dwayne Ulrich: It's like, oh my gosh, you're going to deplete your potassium levels because you're going to start offloading all this stuff because it's diuretic.
- 53:42Dwayne Ulrich: We saw in our podcast on caffeine that it doesn't hold true to the data.
- 53:49Dustin Lambert: It doesn't, so I don't think that that's an issue at all, I think there may be some effect of increased sodium excretion to go along with it.
- 53:57Dustin Lambert: So, in terms of the coffee, there was a trial that we looked at where they did measure sodium excretion and it was higher in the coffee group than the water group, is higher in the coffee group than the water group.
- 54:09Dustin Lambert: So the fact that we see blood pressure reductions independent of weight loss, from from artificial, artificially suited beverages that may have caffeine, I think there may be a case to be made there too that you're having an increased sodium excretion from that which is going to put the hydration status, but also with the blood pressure thing yeah, that's and that's a positive.
- 54:25Dwayne Ulrich: But again, going back to what I was saying is like, as far as other base minerals in your body, you're not going to deplete things like potassium, magnesium and stuff like that.
- 54:34Dwayne Ulrich: There is a sodium offload.
- 54:36Dwayne Ulrich: That is a boost.
- 54:37Dwayne Ulrich: I mean that's a plus.
- 54:39Dwayne Ulrich: But I was just saying overall elements in your body.
- 54:42Dwayne Ulrich: It's just you're not going to offload a bunch of stuff.
- 54:45Dwayne Ulrich: That's going to hurt you.
- 54:46Philip Pape: Go eat a banana, go eat a banana.
- 54:48Dwayne Ulrich: Absolutely not going to offload a bunch of stuff to hurt you Go eat a banana?
- 54:50Philip Pape: Go eat a banana, Absolutely Actually this.
- 54:55Philip Pape: Then sodium comes up as a thing too because the soda I'm drinking has 60 milligrams and some diet sodas have quite a bit more 200, 200 something milligrams.
- 54:59Philip Pape: And I know, coach Lamba, you're big into not over subscribing to the fact that we're under salted.
- 55:07Philip Pape: Right, there's this narrative that we're all under salted and maybe some people have too much salt and it's causing high blood pressure.
- 55:12Philip Pape: It's interesting because there is a lot of salt.
- 55:15Philip Pape: I guess I don't know Relative.
- 55:17Philip Pape: Is it a decent amount of sodium that we should be worried about?
- 55:19Philip Pape: It sounds like it reduces your blood pressure, so maybe not.
- 55:23Dustin Lambert: Is there a lot of sodium in the diet sodas?
- 55:25Dustin Lambert: Yes, yes, yeah.
- 55:29Dustin Lambert: So it varies from one to the.
- 55:30Dustin Lambert: You know, I think diet coke has like 55 milligrams of sodium, 40 milligrams of sodium, so so it varies.
- 55:34Dustin Lambert: Like, am I concerned about somebody having a diet soda with 40 milligrams of sodium three or four times a day?
- 55:40Dustin Lambert: Not really, you know.
- 55:42Dustin Lambert: So we're looking to stay under 2300 for the day.
- 55:44Dustin Lambert: You know, if you have three or four diet cokes, you know we're at 200, like there's plenty left to salt your food.
- 55:52Philip Pape: All right, all right.
- 55:52Philip Pape: Um, there's one other benefit I thought of, and that is a cavity cavity risk.
- 55:57Dwayne Ulrich: Oh yeah.
- 55:58Philip Pape: Which.
- 55:59Dwayne Ulrich: I took a deep doubt on this.
- 56:01Dwayne Ulrich: I just oh, did you.
- 56:02Philip Pape: Okay.
- 56:02Dwayne Ulrich: Yeah, I found it fascinating.
- 56:03Dwayne Ulrich: So I think we just need, first of all, we need to take a look at sugar sweetened beverages first.
- 56:09Dwayne Ulrich: It's just like your mama said, that stuff's going to rot your teeth out.
- 56:15Dwayne Ulrich: So for a child, there's a term for it.
- 56:17Dwayne Ulrich: I just can't remember what it is Primary dentin, I can't remember.
- 56:21Dwayne Ulrich: Anyway, for a child, sugar sweetened beverages are just caustic, just tear the child's teeth up.
- 56:31Dwayne Ulrich: If they drink a little bit of a soda man, you need to wash those teeth out and brush them.
- 56:34Dwayne Ulrich: And then in your teens, your young adulthood, it doesn't have quite an effect.
- 56:39Dwayne Ulrich: An older person I'm still talking about sugar-sweetened beverages so for an older person, you don't have the cavity issue but you have an erosion.
- 56:50Dwayne Ulrich: It increases erosion in your teeth.
- 56:52Dwayne Ulrich: But now going to the artificially sweetened ones, so there's a thing that happens is that I think it's called karyogenic is that when your body, when you drink a sugar sweetened beverage, the sugars break down into an acid and so that's what's tearing up the enamel in your teeth.
- 57:09Dwayne Ulrich: So artificially sweetened beverages aren't karyogenic, so your body doesn't take that stuff and generate an acid.
- 57:18Dwayne Ulrich: So there's really not much impact on your teeth, even on what's called a primary dentinate I think it is, and middle age, like so early teens to 20-something and even adults.
- 57:33Dwayne Ulrich: There's not that much of an impact there.
- 57:34Dwayne Ulrich: The only impact that I found in studies that I was looking at was that artificial sweeteners are used a lot on foods or treats, especially that are highly acidic, and so whatever you're going to get is probably going to be coming from a higher acidic type food or treat or sweets or whatever Gosh.
- 57:55Dwayne Ulrich: The first thing that comes to my mind is those nasty little like the worms and the.
- 58:00Philip Pape: The gummy worms.
- 58:01Dwayne Ulrich: Put the sugar on them, sour patch gummy worms, sour patch kids, those, I hate those things.
- 58:08Dwayne Ulrich: But so you know, if you find those with artificial sweeteners, you know it's not the sweetener that's tearing you up, it's going to be just the acid from the food.
- 58:16Dwayne Ulrich: Sure, sure.
- 58:16Dwayne Ulrich: So it's a plus.
- 58:17Philip Pape: I mean, all right, hey, we're busting this stuff in right, can you have the sugar sweetened beverages?
- 58:23Philip Pape: Pshe, phosphoric acid is an ingredient in soda and that might be a cool episode for you guys to do, because that's another one that has been fear mongered with like they'll show teeth in a vat of phosphoric acid and it's like rotting away, and then you look at the amount that have to be exposed to for long periods of time, far beyond just what your saliva rinses from you and hopefully you brush your teeth.
- 58:46Philip Pape: It's a non-concern, but it's interesting how the acidity from the sugar breaking down is more the concern, and then the artificial sweetener tends to solve that problem via substitution.
- 58:57Philip Pape: So now we're just finding so many cool things here today.
- 59:00Philip Pape: So, guys, as we wrap up, I think we've addressed the general premise here about whether diet soda is harmful or not, and in what context and what the evidence is, and we're kind of scratching the surface, because I realize there's a lot out there.
- 59:13Philip Pape: Is there one thing that we didn't cover that you wish I had brought up?
- 59:18Dustin Lambert: Yeah On whether or not these things are banned in Europe.
- 59:21Dustin Lambert: Wow.
- 59:22Dwayne Ulrich: Didn't even think of that.
- 59:23Philip Pape: Okay, that's a good one, let's go there.
- 59:26Dustin Lambert: Yeah, so that's a common criticism on a line by the fear mongers, and you know the answer is, quite frankly, no.
- 59:35Dustin Lambert: So what people are missing about things that are supposedly banned in Europe?
- 59:40Dustin Lambert: So they'll say a lot of things are banned in Europe.
- 59:42Dustin Lambert: Bha, bht I think aspartame was the latest one.
- 59:45Dustin Lambert: Europe doesn't use the word.
- 59:47Dustin Lambert: They have an e-designation for food additives.
- 59:50Dustin Lambert: So if you want to go and look at it, you can just Google European Food Safety Authority food additive list and you'll find e-designations for things.
- 59:59Dustin Lambert: Aspartame is under the e-designation E951.
- 1:00:02Dustin Lambert: Ak is E950.
- 1:00:04Dustin Lambert: Sucralose is E955.
- 1:00:07Dustin Lambert: Yeah, so these things aren't banned in Europe.
- 1:00:10Dustin Lambert: The people that you're listening to just don't know anything.
- 1:00:13Dustin Lambert: There we go.
- 1:00:16Philip Pape: Anything to add to that, Dwayne?
- 1:00:18Dwayne Ulrich: No, but well, I will add this there are some plant extracts that are banned in Europe as well, Like cannabis.
- 1:00:24Dwayne Ulrich: Cannabis good Maybe that's a podcast for one of us to do.
- 1:00:33Dwayne Ulrich: Yeah, I'm with coach on that.
- 1:00:35Dwayne Ulrich: Yeah, yeah, yeah, yeah.
- 1:00:36Philip Pape: I mean, I tend to my skepticism.
- 1:00:38Philip Pape: Hairs go way up when you say Europe or California.
- 1:00:41Dustin Lambert: So yeah, same difference man.
- 1:00:43Philip Pape: Same difference.
- 1:00:44Philip Pape: Yeah, yeah, yeah, all right, man Cool.
- 1:00:46Philip Pape: So your friends?
- 1:00:53Philip Pape: Yeah, yeah, all right, man Cool.
- 1:00:54Philip Pape: So this has been awesome.
- 1:00:54Philip Pape: I think we had fun.
- 1:00:54Philip Pape: I think I learned a few things that I didn't know, which is always real, real gold.
- 1:00:56Philip Pape: When I have these conversations, I do want to ask you where you want people to find, you guys.
- 1:00:57Philip Pape: But since, for sure, you have a podcast, the working way to LLC podcast, is there a specific episode that I'm thinking the artificial sweetener one, but maybe another one that you want to send them to and we can throw it in the show notes?
- 1:01:07Dustin Lambert: The artificial sweetener one would probably be good.
- 1:01:09Dustin Lambert: It ties right into this.
- 1:01:10Dustin Lambert: And then there is the artificial food dyes.
- 1:01:13Dustin Lambert: I think would be another excellent one for people to listen to, to get a better idea on how to kind of understand the research regarding these food additives.
- 1:01:23Dustin Lambert: Cool.
- 1:01:23Philip Pape: Yeah, that's a good one.
- 1:01:24Philip Pape: Especially, people talk about protein powders, for example, which have sometimes have the dyes in them and they're consuming lots of them, so we'll I'll include a couple of those in there.
- 1:01:33Dwayne Ulrich: I'm going to point them towards caffeine, the coffee thing.
- 1:01:36Philip Pape: The coffee one.
- 1:01:36Philip Pape: Yeah, yeah, all right.
- 1:01:37Philip Pape: So we're going to have a nice library of links in here Point people to.
- 1:01:40Philip Pape: Is there anything else you want to send them to IG or anything else?
- 1:01:49Dustin Lambert: Not really.
- 1:01:49Dustin Lambert: I am on Instagram, but not terribly.
- 1:01:50Dustin Lambert: I'm just not too terribly active on social media, so the podcast is probably the best way, sounds good, dwayne, same thing.
- 1:01:55Philip Pape: Just go to the podcast.
- 1:01:56Dwayne Ulrich: Yeah, go to the podcast, Absolutely.
- 1:01:59Philip Pape: All right, man.
- 1:01:59Philip Pape: Well, thanks guys for coming on.
- 1:02:00Philip Pape: We threw this together last minute this week and it came together really nicely and I hope people learned a ton.
- 1:02:06Philip Pape: That's the goal is to learn to be curious, to apply this to themselves, to ask questions, don't just assume that what you see on Instagram is correct and that's the way we do it.
- 1:02:16Philip Pape: Thanks for coming on, guys.
- 1:02:17Philip Pape: Yeah.
- 1:02:17Dwayne Ulrich: Good deal.
- 1:02:17Philip Pape: Yeah, thanks for having us Thanks a lot.