Shows / Healthy Dialogue
Healthy Dialogue
Go beyond the latest discoveries with nuanced, in-depth conversations in Healthy Dialogue, a podcast from the JAMA Network. Host and JAMA Senior Editor, Derek C. Angus, MD, MPH, sits down with the world's leading experts to explore the most pressing issues in health and health care.
Episodes
Healthy DialogueAlzheimer Disease Blood Biomarkers
Biomarkers for Alzheimer disease (AD) provide insight into disease processes and may aid clinical diagnosis for individuals with cognitive impairment. Author…
Healthy DialogueRisankizumab for Ulcerative Colitis
Ulcerative colitis can significantly decrease quality of life. A third of patients have persistent symptoms with tumor necrosis factor inhibitors and nearly 1…
Healthy DialogueInfluence of Endometriosis Typology on Ovarian Cancer Risk
What are the ovarian cancer risks associated with endometriosis subtypes? Author Karen C. Schliep, PhD, MSPH, of the University of Utah joins JAMA Deputy…
Healthy DialogueNicotine Pouch Use in the US
Oral nicotine pouches are becoming more popular in the US, based on a survey performed in 2022. Hongying Daisy Dai, PhD, from Nebraska Medical Center, Omaha…
Healthy DialogueThe Future of Pediatrics in the US
Availability of pediatric care is decreasing, despite the growing complexity of pediatric care needs. Match rates for pediatric residency continue to decline…
Healthy DialogueTelehealth Abortion Safety and Effectiveness
Facilitating safe and timely health care for individuals planning medication abortion is a reproductive health care priority. Lauren J. Ralph, PhD, MPH, and…
Healthy DialogueSudden Death, Calcium Release Deficiency Syndrome, and a New ECG Finding
Can a new ECG finding identify individuals at risk for dying suddenly? Jason D. Roberts, MD, of McMaster University joins JAMA Associate Editor Gregory M…
Healthy DialogueContinuous vs Intermittent β-Lactam Antibiotic Infusions in Patients With Sepsis
Joel M. Dulhunty, MD, PhD, Royal Brisbane and Women's Hospital, and Jason A. Roberts, BPharm, PhD, University of Queensland Centre for Clinical Research, join…
Healthy DialogueIntegrating Clinical Trials With the Practice of Medicine
Randomized clinical trials (RCTs) frequently fail to generate knowledge relevant to practice, while practice patterns are frequently unsupported by RCT…
Healthy DialogueEvidence Against Nitrogen's Use for the Death Penalty
Forced nitrogen inhalation was used by the state of Alabama to execute Kenneth Smith on January 25, 2024. Some politicians, attorneys general, and health care…
Healthy DialogueOutcomes After Living Kidney Donation
Guidelines call for better evidence on the health outcomes after living kidney donation. Author Amit X. Garg, MD, PhD, London Health Sciences Centre, and…
Healthy DialogueCardiac Amyloidosis and the V142I Transthyretin Variant
What is the natural history and cardiovascular burden of the V142I transthyretin variant among US Black individuals who carry this variant? Senthil Selvaraj…
Healthy DialogueRacial and Ethnic Disparities in All-Cause and Cause-Specific Mortality Among US Youth
Between 2019 and 2021, pediatric mortality rates had the largest increases in at least half a century. Steven H. Woolf, MD, MPH, of Virginia Commonwealth…
Healthy DialogueSmoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement
When initial treatment with varenicline or nicotine replacement doesn't work, does increasing dosage improve smoking cessation rates? Paul Cinciripini, PhD, of…
Healthy DialogueExamining Mortality Disparities by Sexual Orientation Among Female Nurses
Extensive evidence documents health disparities for lesbian, gay, and bisexual (LGB) women, including worse physical, mental, and behavioral health than…
Healthy DialogueStewardship Prompts to Improve Antibiotic Selection for Pneumonia and Urinary Tract Infection
Can real-time EHR–generated recommendations safely reduce antibiotic use in hospitalized patients with pneumonia or UTI? Shruti K. Gohil, MD, MPH, of the…
Healthy DialogueAdvancing Climate Action Through Academic Health Systems
Climate action is an urgent public health imperative. Climate change is causing excess morbidity and mortality and posing an increasing threat to mental health…
Healthy DialogueThe Evolution of Screening Tools for Prostate Cancer
The utility of prostate-specific antigen (PSA) screening for prostate cancer detection is impacted by detection of cancers with low risk of mortality…
Healthy DialogueRegional Interventions to Prevent Multidrug-Resistant Organisms
Infections due to multidrug-resistant organisms (MDROs) are difficult to treat with increased morbidity, mortality, length of hospitalization, and health care…
Healthy DialogueMifepristone–Science, Abortion Care, and Politics
The US Supreme Court will soon decide a case challenging the US Food and Drug Administration's (FDA's) approval of mifepristone. Author Holly Fernandez Lynch…
Healthy DialogueHow Do Multimodal Large Language Models Perform on Clinical Vignette Questions?
How did GPT-4 Vision, a model that can work with images and text as input, perform when answering clinical challenge questions from medical journals? Daniel…
Healthy DialogueDoes Treating Attention-Deficit/Hyperactivity Disorder Reduce Mortality?
An observational study by Lin Li, PhD, and colleagues, published in JAMA, found that pharmacotherapy was associated with reduced mortality in individuals with…
Healthy DialogueDelivering Effective Messages in the Patient-Clinician Encounter
Introducing JAMA's new Communicating Medicine series, JAMA Associate Editor Anne Cappola, MD, ScM, discusses strategies for delivering effective messages in…
Healthy DialogueWhy Does PrEP Use Lag in Cisgender Women?
How will new study results inform HIV prevention in the US and globally? JAMA Deputy Editor Preeti Malani, MD, MSJ, and author Jeanne Marrazzo, MD, MPH…
Healthy DialogueUpdated Pediatric Sepsis Criteria—Transitioning From SIRS to Phoenix
JAMA Associate Editor Romain Pirracchio, MD, MPH, discusses context and implications of the new pediatric sepsis criteria with authors Hallie Prescott, MD…
Healthy DialogueRenter Eviction, Excess Mortality, and COVID-19
Renters who received eviction filings experienced excess mortality associated with the COVID-19 pandemic. JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD…
Healthy DialogueAzithromycin to Prevent Childhood Mortality in Sub-Saharan Africa
Childhood death rates remain high in some areas of sub-Saharan Africa, despite global reductions in childhood mortality. JAMA Deputy Editor Preeti Malani, MD…
Healthy DialogueEvaluating the Effectiveness of Bivalent COVID-19 Vaccines in Children and Adolescents
Bivalent mRNA COVID-19 vaccines were recommended for children and adolescents aged 5 to 17 years in the US, but were they effective? JAMA Associate Editor…
Healthy DialogueAnxiety and Depression Symptoms After the Dobbs Abortion Rights Decision
Following the Dobbs decision, females aged 18-45 years living in states with "trigger laws" that restricted access to abortion reported a greater increase in…
Healthy DialoguePatient-Centered Palliative Care
JAMA Deputy Editor Preeti Malani, MD, MSJ, and author Alexander K. Smith, MD, MS, MPH, University of California, San Francisco, discuss the importance of 2 new…
Healthy DialogueDialysis Facility Performance and Social Risk in the First Year of the ESRD Treatment Choices Model
Dialysis facilities in the US are financially rewarded for higher rates of home dialysis and kidney transplant, but facilities that serve patients with high…
Healthy DialogueAlpha-Gal Syndrome
Alpha-gal syndrome is a food allergy to red meat products that develops after affected individuals are bitten by a tick. JAMA Deputy Editor Kristin Walter, MD…
Healthy DialoguePrivate Equity Acquisition and Hospital-Acquired Adverse Events in the US
The effects of private equity acquisition of US hospitals on the quality of inpatient care and patient outcomes remain largely unknown. JAMA Associate Editor…
Healthy DialogueEffect of Dietary Sodium on Blood Pressure
Does reducing dietary sodium benefit patients already taking antihypertensive medication? JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, speaks…
Healthy DialogueRisks Associated With Cannabis Exposure During Pregnancy
Cannabis use is increasing among reproductive-age individuals. JAMA Deputy Editor Linda Brubaker, MD, MS, discusses the associated risks of cannabis exposure…
Healthy DialogueNeonatal Outcomes Following Serial Amnioinfusions for Bilateral Renal Agenesis
Bilateral renal agenesis results in lethal neonatal pulmonary hypoplasia. New evidence from an amnioinfusion trial is available. JAMA Deputy Editor Linda…
Healthy DialogueIncreasing Cervical Cancer Screening With Self-Sampling HPV Kits at Home
Cervical cancer screening is effective when done as recommended. JAMA Deputy Editor Linda Brubaker, MD, speaks with Rachel L. Winer, PhD, MPH, of the…
Healthy DialogueSmall-Volume Blood Collection Tubes May Reduce Transfusions in Intensive Care
Small-volume blood collection tubes may decrease red blood cell transfusions in intensive care units without affecting laboratory analysis. JAMA Associate…
Healthy DialogueFitness Trackers to Guide Advice on Activity Prescription
Fitness trackers are a group of devices including watches, phones, and rings that track physical activity. JAMA Executive Editor Gregory Curfman, MD, speaks…
Healthy DialogueMedicare's Historic Prescription Drug Price Negotiations
JAMA Senior Editor Kristin Walter, MD, MS, and Lawrence O. Gostin, JD, JAMA Legal and Global Health Correspondent and Faculty Director of the O'Neill Institute…
Healthy DialogueTraditional Chinese Medicine Meets Evidence-Based Medicine in the Acutely Infarcted Heart
JAMA Executive Editor Gregory Curfman, MD, speaks with Richard G. Bach, MD, professor of medicine and medical director of the cardiac intensive care unit at…
Healthy DialogueOptical Coherence Tomography (OCT): Imaging Modalities in Clinical Practice
Optical coherence tomography (OCT) is a powerful imaging tool used across multiple clinical disciplines. JAMA Executive Editor Gregory Curfman, MD, speaks with…
Healthy DialogueNasal Iodophor vs Nasal Mupirocin With Chlorhexidine Baths to Prevent Infections in Adult ICUs
Nasal mupirocin plus chlorhexidine baths in ICUs prevents methicillin-resistant Staphylococcus aureus (MRSA) infections but raises concern about antibiotic…
Healthy DialogueIs Remote Ischemic Conditioning (RIC) an Effective Treatment for Acute Stroke?
It's been unclear whether remote ischemic conditioning (RIC) with transient cycles of limb ischemia and reperfusion is an effective treatment for acute stroke…
Healthy DialogueThe Connection Between SARS-CoV-2 and Type 1 Diabetes Risk in Young Children
During the COVID-19 pandemic, the incidence of diabetes in childhood increased. JAMA Associate Editor Anne R. Cappola, MD, ScM, and Ezio Bonifacio, PhD, from…
Healthy DialogueTwo-Year Outcomes After Minimally Invasive Surfactant Therapy
Many premature infants with respiratory distress are now supported with continuous positive airway pressure, or CPAP, rather than intubation and ventilation…
Healthy DialogueSedentary Behavior and Dementia
There is an established link between sedentary behavior and cardiovascular disease, but the association between sedentary behavior and dementia is unclear…
Healthy DialoguePsilocybin for Major Depressive Disorder
In a new study, psilocybin showed promise as a treatment for major depressive disorder (MDD). JAMA Associate Editor Donald C. Goff, MD, speaks with author…
Healthy DialogueNeurodevelopmental Effects of Antenatal IV Magnesium Sulfate Between 30-34 Weeks' Gestation
Magnesium sulfate is widely recommended for neuroprotection in pregnancies at risk of preterm delivery. However, the optimal gestational age for use is…
Healthy DialogueAtorvastatin to Reduce Risk of Anthracycline-Associated Cardiac Dysfunction
Anthracyclines are used to treat a variety of cancers, but treatment may be limited by cardiac toxicity. JAMA Executive Editor Gregory Curfman, MD, discusses a…
Healthy DialogueCardiovascular Health Counseling in Pregnant and Postpartum Individuals
Cardiovascular health is essential to everyone, but especially important to address in individuals who can become or who are pregnant or postpartum. JAMA…
Healthy DialogueBempedoic Acid in Statin-Intolerant Patients
Bempedoic acid is an effective option for some statin-intolerant patients with an elevated predicted risk of cardiovascular events. However, as JAMA Executive…
Healthy DialogueGenomic Sequencing for Ill Newborns
The performance of whole-genome sequencing in comparison with targeted genomic testing methods is not well understood. In this podcast, JAMA Associate Editor…
Healthy DialogueLetermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus Disease in High-Risk Kidney Transplant Recipients
Valganciclovir is standard cytomegalovirus (CMV) prophylaxis in high-risk kidney transplant recipients, but its use is limited by myelosuppression. JAMA Deputy…
Healthy DialogueThe Costs of Quality Reporting
US hospitals report data on numerous quality metrics to government and independent rating organizations, but the cost of doing so is not well known. JAMA…
Healthy DialogueUSPSTF Recommendations: Screening for Depression and Suicide Risk in Adults, and Screening for Anxiety Disorders in Adults
Interview with Michael Silverstein, MD, MPH, USPSTF chair and coauthor of Screening for Depression and Suicide Risk in Adults, and Screening for Anxiety…
Healthy DialogueMortality and Years of Potential Life Lost in the US Black Population
The US Black population experienced more than 80 million excess years of life lost compared with the White population over a recent 22-year period. JAMA Editor…
Healthy DialogueLegal Risks of Abortion Miscoding
Intentional miscoding of abortion services may put clinicians and hospital systems at legal risk. JAMA Senior Editor Linda Brubaker, MD, MS, and Carmel…
Healthy DialoguePhysician as Writer: Abraham Verghese Reflects on the Art of the Craft of Writing Fiction
The Covenant of Water, Stanford University professor Dr Abraham Verghese's long-awaited follow-up to his 2009 novel Cutting for Stone, traces the lives of a…
Healthy DialogueThe Continued Legal Battle to Undercut the ACA
The ACA's preventive services mandate requires insurers to cover, without charge, nearly 200 basic primary care services. But now, a federal judge has issued a…