Shows / Applied Clinical Trials
Episodes
Applied Clinical TrialsACT Brief: Lilly Seeks FDA Priority Review for Oral GLP-1 as Bispecific Antibody Trials Redefine Ethical Standards
In today’s ACT Brief, we explore how Eli Lilly’s orforglipron could become the first oral GLP-1 therapy reviewed under FDA’s new national priority program, and…
- Applied Clinical Trials
ACT Brief: AstraZeneca Expands Immunotherapy Reach as Thermo Fisher’s $8.8B Deal Signals New Phase for Digital Trials
In today’s ACT Brief, we spotlight the industry’s push to reduce site technology burden, AstraZeneca’s broad survival gains from the MATTERHORN trial, and…
Applied Clinical TrialsACT Brief: AI, Equity, and Innovation Drive Clinical Research Forward
In today’s ACT Brief, we explore how AstraZeneca is redefining gastric cancer care through the MATTERHORN trial, Phesi’s Gen Li shares how AI and patient data…
- Applied Clinical Trials
ACT Brief: AI Partnerships, Data-Driven Site Activation, and FDA Approval for Omvoh’s Single-Injection Regimen
In today’s ACT Brief, we spotlight how new OpenAI collaborations are transforming drug development, how AI is driving smarter site activation in global trials…
- Applied Clinical Trials
ACT Brief: AI Expands Global Site Leadership as Ozempic Shows Potential to Reverse Biological Age
In today’s ACT Brief, we examine how artificial intelligence is helping uncover site leaders in underserved regions to strengthen trial diversity—and explore…
- Applied Clinical Trials
ACT Brief: AI Partnerships, Global Trial Access, and a New Option for Menopause Symptoms
In today’s ACT Brief, we spotlight expanding AI collaborations transforming life sciences, the role of patient-centric technology in improving global trial…
- Applied Clinical Trials
ACT Brief: Digital Consent, Global Diversity, and Clinical Setbacks Shape Today’s Clinical Research Landscape
Today’s ACT Brief explores how eConsent is modernizing participant engagement, highlights new data on global representation in breast cancer trials, and…
- Applied Clinical Trials
ACT Brief: AI Innovations, Vision Trial Breakthroughs, and a Major Industry Acquisition
In today’s ACT Brief, we revisit key insights from SCOPE Summit 2025 on AI and pragmatic trials, examine Genentech’s Phase III vamikibart data in uveitic…
- Applied Clinical Trials
ACT Brief: AI-Driven Oversight, Biotech Acceleration Strategies, and a Major Win in Bladder Cancer
Today’s ACT Brief highlights how artificial intelligence is transforming trial data management, why biotechs are embracing parallel execution to accelerate…
- Applied Clinical Trials
ACT Brief Weekly Recap: AI Innovation, Industry Resilience, and Supply Chain Readiness
In this week’s Applied Clinical Trials Brief, we highlight key findings from the 2025 State of the Industry Survey, explore how AI is transforming trial…
- Applied Clinical Trials
ACT Brief Weekly Recap: Clinical Research Faces Funding Strain, Data Evolution, and a Shift in Outsourcing Models
Last week’s top stories explored how NIH’s shutdown plan is testing research resilience, why data infrastructure must precede AI adoption in 2025, and how…
Applied Clinical TrialsReimagining Clinical Operations Through Artificial Intelligence
In this episode of the ACT Podcast, we highlight a recent Q&A featuring Ibrahim Kamstrup-Akkaoui, vice president of data systems innovation at Novo Nordisk…
- Applied Clinical Trials
ACT Brief Weekly Recap: AI Monitoring, Biotech Scaling, and Site Interoperability Lead This Week’s Top Stories
A look back at last week’s most-viewed content highlights how AI-driven monitoring could improve management of cytokine release syndrome in oncology, how…
- Applied Clinical Trials
ACT Brief Weekly Recap: Data Innovation, Cybersecurity, and Contracting Bottlenecks in Clinical Trials
Last week’s top stories explored the push for digital-first clinical data systems, why cybersecurity must be central in CRO qualification, and how AI-driven…
- Applied Clinical Trials
ACT Brief Weekly Recap: Partnerships, Site Networks, and AI Reshaping Clinical Trials
This episode of the Applied Clinical Trials Brief highlights a new global collaboration between two industry leaders, explores how site networks can address…
- Applied Clinical Trials
ACT Brief: Policy Shifts, FDA Inspections, and Tariffs Pose New Challenges for Clinical Trials
In this episode of the ACT Brief, we spotlight an earlier interview with Ron Lanton, partner at Lanton Law, in which he discussed how rising drug costs…
- Applied Clinical Trials
ACT Brief Weekly Recap: How AI, eClinical Innovation, and Policy Shifts Are Reshaping Clinical Research
In this week’s Applied Clinical Trials Brief, we recap three top stories: Novo Nordisk’s stepwise approach to AI adoption, new perspectives on eClinical…
- Applied Clinical Trials
ACT Brief Episode 8: Expert Insights on the Future of Obesity Drug Trials
In this episode of the Applied Clinical Trials Brief, Shipra Patel, global therapeutic area section head for endocrinology and global head of pediatrics at…
- Applied Clinical Trials
ACT Brief Episode 7: Veeva and Merck Trial Efficiency, DCT Barriers, and Glucose Monitoring Strategies
In this episode of the Applied Clinical Trials Brief, we recap our three most-viewed articles of the week—spotlighting Veeva and Merck’s push for…
- Applied Clinical Trials
ACT Brief Episode 6: Supreme Court Ruling, VK2735 Obesity Trial, and Padcev-Keytruda Survival Gains
In this episode of the Applied Clinical Trials Brief, we recap our three most-viewed stories of the week—covering the Supreme Court’s decision to uphold NIH…
- Applied Clinical Trials
ACT Brief Episode 5: How Digital Twins and AI Are Reshaping Clinical Trials
In this episode of the Applied Clinical Trials Brief, we spotlight a recent video interview in which Jon Walsh, founder and chief scientific officer of…
- Applied Clinical Trials
ACT Brief Episode 4: New Data on Trial Delays, Hybrid Payment Models, and Managing Complexity
In this episode of the Applied Clinical Trials Brief, we recap our three most-viewed articles of the week—featuring updated cost estimates for trial delays…
- Applied Clinical Trials
ACT Brief Episode 3: Breaking Down Data Silos to Accelerate Clinical Trials
In this episode of the Applied Clinical Trials Brief, we spotlight a recent video interview with Luke Wilson of Thermo Fisher Scientific in which he shared…
- Applied Clinical Trials
ACT Brief Episode 2: FDA Oversight, Vaccine Funding Cuts, and the Digital Future of Clinical Trials
In this episode of the Applied Clinical Trials Brief, we recap our three most-viewed stories of the previous week with a look into the FDA’s heightened…
- Applied Clinical Trials
ACT Brief Episode 1: Placebos, Politics, and the Ethics of Vaccine Trials
In this episode of the Applied Clinical Trials Brief, we examine the renewed push for placebo-controlled vaccine trials in the US, why experts warn it violates…
Applied Clinical TrialsUnifying Industry to Better Understand GCP Guidance
David Nickerson, head of clinical quality management at EMD Serono, executive sponsor of TransCelerate's ICH E6(R3) Initiative & PhRMA topic lead on the ICH…
Applied Clinical TrialsImproving Relationships and Diversifying the Site Selection Process
Liz Beatty, co-founder and chief strategy officer, Inato, discusses a number of topics around site engagement including community-based sites, the role of…
Applied Clinical TrialsReaching Diverse Patient Populations With Personalized Treatment Methods
Daejin Abidoye, head of solid tumors, oncology development, AbbVie, discusses a number of topics around diversity in clinical research including the industry’s…
Applied Clinical TrialsDriving Diversity with the Integrated Research Model
Ashley Moultrie, CCRP, senior director, DEI & community engagement, Javara discusses current trends and challenges with achieving greater diversity in clinical…
Applied Clinical TrialsAI in Clinical Trials - A Long, But Promising Road Ahead
Stephen Pyke, chief clinical data and digital officer, Parexel, gives a broad overview of the use of artificial intelligence in clinical development and how…
Applied Clinical TrialsIncluding Women of Childbearing Age in Clinical Research
In recognition of International Women's Month, we're featuring this recent talk between Associate Editor Miranda Schmalfuhs and Marie Teil, Global Head of…
Applied Clinical TrialsImproving Engagement While Maintaining Data Integrity & Validity
In recognition of Women's Health Month, we're featuring this recent talk between Associate Editor Miranda Schmalfuhs and uMotif's Chief Product Officer, Julia…
Applied Clinical TrialsDiversity in Clinical Trials: The Need to Take Action
Gadi Saarony, CEO of Advarra, examines the current state of diversity in clinical research. He discusses the need for industry to take more action in making…
Applied Clinical TrialsBringing the Clinical Trials Industry Together
Micah Lieberman, Executive Director, Conferences (CHI) & Co-Founder, VP, Community and Business Development (ClinEco) shares the origin story of ClinEco and…
Applied Clinical TrialsManaging Digital Studies in the Current Landscape
Flo Mowlem, VP of Science at ObvioHealth highlights her career path and experience with eCOA. She discusses what is currently happening in the digital clinical…
Applied Clinical TrialsCombining Awareness and Innovation
Jared Baeten, Vice President, Clinical Development, HIV Franchise Head at Gilead Sciences discusses how he chose to focus his career path on HIV research and…
Applied Clinical TrialsSCOPE EUROPE 2023 Recap
Editor Andy Studna shares some sound bytes from KOLs he spoke with during SCOPE EUROPE 2023.
Applied Clinical TrialsBringing Innovation To The Clinic
Rinol Alaj, senior director, head of clinical outcomes assessment & patient innovation at Regeneron and Jaclyn Patterson, head, clinical trial management &…
Applied Clinical TrialsAdvancing Rare Disease Research and the Development of Targeted Therapies
Michael Pourdehnad, MD, senior vice president, head of early clinical development, hematology/oncology & cell therapy at Bristol Myers Squibb discusses the…
Applied Clinical TrialsLeveraging The Power Of AI
Najat Khan, PhD, chief data science officer and global head, strategy, portfolio & operations, R&D, The Janssen Pharmaceutical Companies of Johnson & Johnson…
Applied Clinical TrialsA Look at the Current State of Sites
Jimmy Bechtel, MBA, vice president of site engagement for the Society of Clinical Research Sites (SCRS) discusses his career path and how he became so…
Applied Clinical TrialsWhere Digital Health Technology Intersects With Pharma
Chris Economos, Vice President and Head of Life Sciences at Eko, discusses his career journey from pharma to digital health technology, where he recognized the…
Applied Clinical TrialsAI Is The New Electricity
Michael Ibara, Chief Data Officer, Elligo Health Research, discusses the history of mining healthcare data and using it to identify safety events, as well as…
Applied Clinical TrialsBuilding Clinical Trials With Trust
Charlotte Grayson, MD, clinical research medical director, Privia Health highlights her journey to becoming a physician and eventually getting involved with…
Applied Clinical TrialsThe Evolution of Early-phase Research
Colleen Hoke, Co-Founder and CEO of ObjectiveHealth discusses her career in early-phase research and the transition from working with a startup to a major…
Applied Clinical TrialsThe Trust Factor In Data
Craig Serra, Head of Commercial Solutions and Partnerships at Flatiron Health’s Clinical Research Business Unit, discusses data and its many uses in clinical…
Applied Clinical TrialsAddressing The Gap Between Tech In Every Day Life Vs. Tech In Clinical Trials
Jennifer Duff, General Manager, Zelta Clinical Trials Solutions, Merative (formerly IBM Watson Health), discusses her leadership philosophy, the number of name…
Applied Clinical TrialsCell And Gene Therapy: Still On A Learning Curve
Chris Learn, PhD, PMP, Vice President, Cell and Gene Therapy Center of Excellence, Parexel describes highlights of his career, what originally spurred his…
Applied Clinical TrialsClinical Studies Take Teamwork
Doug Warner, MD and CMO for eFFECTOR Therapeutics, a clinical stage biopharma targeting oncology, discusses the complexities of oncology clinical trials…
Applied Clinical TrialsDrug Development Agility with Safety First
Peter Benton, President and CO-CEO for Worldwide Clinical Trials, leads a diverse team of more than 3,000 people in more than 60 countries. Benton speaks about…
Applied Clinical TrialsExamining the Neurology/Neuromuscular Space
In this episode of the Applied Clinical Trials podcast, we are joined by Sindhu Ramchandren, MD, Director, Clinical Leader, Neuroscience at Janssen. With…
Applied Clinical TrialsData In Clinical Trials—How Did We Get Here And What’s Next?
Gabriele Brambilla, CEO of Alira Health, discusses the ever-evolving landscape of real-world data; more specifically, how data sharing in clinical research…
Applied Clinical TrialsHealth Equity In Clinical Trials
Rose Blackburne, MD, MBA, Vice President, Global Head, General Medicine, PPD Clinical Research, Thermo Fisher and Margarita Nunez, MD, Principal Investigator…
Applied Clinical TrialsTreat Disease, Not the Symptoms
In this podcast, Dr. Ira Spector discusses how his career journey has epitomized the ability to solve problems, which is essentially the role of drug…
Applied Clinical TrialsA Passion For Pharmacovigilance- Keeping Patients Safe
Beth MacEntee Pileggi, Head of Global Case and Safety Data Management with Janssen Pharmaceuticals of Johnson & Johnson, and Co-Lead of TransCelerate’s…
Applied Clinical TrialsThe Rewarding Path Of Science
Dr. Sean Bohen, CEO of Olema Oncology, discusses his career and significant contributions to the clinical research and development of numerous oncology drugs…
Applied Clinical TrialsIndoUSrare: Purposeful Clinical Research For Rare Diseases In India
Dr. Harsha Rajasimha, Founder and Chairman of IndoUSrare, discusses the emotional reason behind founding the non-profit, programs they offer that are helping…
Applied Clinical TrialsPatient Recruitment Strategies In A True Digital Age
Dan Brenner, Founder and CEO of 1nHealth, discusses his path into clinical research and patient recruitment, the Gold Eagle Next Generation Board, what…
Applied Clinical TrialsSandy Milligan, MD, JD, Head Of Research And Development, Organon
In this podcast, Dr. Milligan makes the case for studying drugs in pregnant and lactating women on an ongoing basis to understand long-term efficacy and…
Applied Clinical TrialsThe Key To Innovation In Clinical Research? Listening.
Jane Myles, Vice President, Clinical Trial Innovation at Curebase, discusses her current role, what led her there, and challenges their clients face with DCTs.