Shows / The a16z Show
The a16z Show
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
Episodes
- The a16z Show
The New CFO: How AI Is Rewriting the Finance Function | Figma CFO Praveer Melwani
AI is moving finance from reconciling what happened last month to helping decide what the business should do next. Figma CFO Praveer Melwani argues that the…
- The a16z Show
The New AI Agents That Shop, Plan, and Gossip
Will we have one AI assistant that does everything, or an entire network of agents that know different parts of our lives? David Pawlan, creator of Assistant…
- The a16z Show
Andrew Huberman’s Three Rules for Better Health and Focus
If you could do only three things for your health, what should they be? Andrew Huberman’s answer is surprisingly straightforward: get bright light shortly…
- The a16z Show
The Robots Already Working in American Factories | Tutor Intelligence
What does it take to build robots that can actually work in factories and warehouses? Tutor Intelligence CEO Josh Gruenstein argues robotics is a systems…
- The a16z Show
How Bending Spoons Built a $20 Billion Compounder | Luca Ferrari
Can relentless optimization create as much value as breakthrough invention? Bending Spoons CEO Luca Ferrari argues that radical innovation can produce…
- The a16z Show
Can AI Fix Professional Networking? | Inside Cosign
What if finding your next job, co-founder, or collaborator depended less on a resume and more on who is willing to vouch for you? Cosign is building a…
- The a16z Show
Why AI Could Turn Small Law Firms Into Billion-Dollar Businesses
What happens when AI makes legal work cheap enough to take cases lawyers couldn't afford to touch before? Eve CEO Jay Madheswaran argues that AI won't just cut…
- The a16z Show
The Startups Rebuilding American Industry | The AD50
America’s defense, energy, manufacturing, and robotics booms are increasingly becoming one story: the rebuilding of the country’s industrial base. This year’s…
- The a16z Show
Mark Cuban on Why AI Could Turn Solo Founders Into Trillionaires
Mark Cuban thinks AI could transform healthcare, but it won’t fix opaque prices and broken incentives on its own. His starting point for employers: run every…
- The a16z Show
Reinventing School for the AI Era | Joe Liemandt, Gagan Biyani & Erik Torenberg
What should school look like if AI can help students learn dramatically faster? Alpha School founder Joe Liemandt argues the answer isn’t to fill the extra…
- The a16z Show
OpenAI: When AI Agents Use Computers Faster Than You
AI agents are approaching a point where they can use computers faster than expert humans, turning the user interface itself into a universal way for AI to…
- The a16z Show
The New Startup Playbook | Box CEO Aaron Levie
Can a 10-person startup outperform a company with hundreds of employees? Box CEO Aaron Levie argues AI agents are giving small teams a level of leverage that…
- The a16z Show
What It Takes to Win as a Founder | Ben Horowitz
What does it take to build a company when AI is changing the rules this quickly? Ben Horowitz argues that technology may make companies easier to start, but…
- The a16z Show
Amazon CEO Andy Jassy on the $220 Billion AI Buildout
Amazon expects to spend roughly $220 billion in CapEx in 2026, yet CEO Andy Jassy says the company is still leaving meaningful AI demand on the table.** He…
The a16z ShowThe Frontier Ideas a16z Wants to Fund | Marc Andreessen, Ben Horowitz & Chris Dixon
a16z is expanding a16z crypto into a16z Frontier, a broader mandate to back founders building at the edges of what's possible. Chris Dixon joins Marc…
- The a16z Show
The Missing Infrastructure for AI Agents: Documents | Reducto’s Adit Abraham
AI agents can reason over enormous amounts of information, but much of the world’s actual work is still trapped in PDFs, spreadsheets, scans, and other formats…
- The a16z Show
What Happens When Everyone Has a Health Expert in Their Pocket? | OpenAI’s Karan Singhal
More than 300 million people use ChatGPT for health and wellness questions each week. OpenAI’s Karan Singhal thinks that’s only the beginning: the longer-term…
- The a16z Show
What Happens When Al Agents Can Spend Your Money?
Why hasn't AI transformed everyday work as quickly as coding? Town CEO Jean-Denis Greze argues the bottleneck isn't intelligence, but making AI useful to…
- The a16z Show
Why Real-World AI Is Harder Than the Benchmark | EliseAI’s Mario Martone
What changes when an AI mistake doesn’t just hurt a benchmark score, but affects someone’s housing or healthcare? EliseAI Head of Applied Research Mario…
- The a16z Show
Why AI Could Finally Fix Healthcare Access | Zocdoc CEO Oliver Kharraz
Why is booking a doctor's appointment still so difficult, and can AI finally change that? Zocdoc CEO Oliver Kharraz argues that the real problem isn't finding…
- The a16z Show
AI Can Write the Code. Can It Run the System? | Grepr CEO Jad Naous
a16z General Partner Martin Casado sits down with Grepr CEO Jad Naous to ask what comes after AI learns to write code: can it also debug and operate the…
- The a16z Show
When AI Agents Start Spending Your Money | Alex Rampell & Terry Angelos
a16z General Partner Alex Rampell sits down with VGS Executive Board Member, Terry Angelos, to unpack what happens to payments when AI agents go from…
- The a16z Show
Can Open Models Keep Up With the AI Frontier? | Nathan Lambert
a16z Partner Lisha Li sits down with AI researcher and Trillium founder Nathan Lambert to ask how durable the gap really is between frontier AI labs and open…
- The a16z Show
Can AI Break Cryptography? What the Experts Actually Think
Could AI break the cryptography protecting everything from crypto wallets and banking to private messages? Recent advances in AI-driven mathematical research…
- The a16z Show
The Race to Recursive Self-Improving AI
a16z General Partner Martin Casado sits down with MakerMaker.AI co-founders Dhaval Adjodah and Owen He to unpack recursive self-improvement, or RSI, and…
- The a16z Show
Nick Bostrom: How Should We Navigate Superintelligence?
Nick Bostrom joins Theo Jaffee and Sofia Puccini on MTS to revisit the ideas about superintelligence and existential risk that he helped bring into the…
- The a16z Show
What Makes a Great Entrepreneur? | Ben Horowitz on Vintage x Vintage
a16z co-founder and General Partner Ben Horowitz joins James Norman on the inaugural episode of Vintage x Vintage for a conversation spanning entrepreneurship…
- The a16z Show
Chips, Memory, and Power | Pat Gelsinger
a16z's Raghu Raghuram and Guido Appenzeller sit down with Playground Global General Partner and former Intel CEO Pat Gelsinger to discuss the next wave of…
- The a16z Show
Building the Cloud for an Agentic World | AWS CEO Matt Garman
a16z’s Raghu Raghuram sits down with AWS CEO Matt Garman to discuss how AI is reshaping the cloud, from the needs of AI-native startups to infrastructure…
- The a16z Show
How Valon Rebuilt a $13 Trillion Industry From Scratch
a16z General Partner Angela Strange sits down with Valon’s Andrew Wang and Linda Du to unpack what it takes to rebuild the infrastructure underneath a $13…
- The a16z Show
Building Defense for the Agentic Era: Kevin Mandia
a16z General Partner David George sits down with Armadin founder and CEO Kevin Mandia to discuss what happens to cybersecurity when attackers can operate at…
- The a16z Show
The Top 100 Consumer AI Apps: Who’s Actually Paying?
a16z Editorial Partner Elena Burger sits down with investing partners Olivia Moore and Josh Elman to unpack the seventh edition of a16z’s Top 100 Consumer AI…
- The a16z Show
David George & Jack Altman on AI, Autonomy, and the Next $25 Trillion
a16z General Partner David George joins Jack Altman on Uncapped to make the case that many of the biggest debates in AI are framed the wrong way. Frontier…
- The a16z Show
Beyond the God Model | Alex Atallah & Amjad Masad
A16z’s Erik Torenberg sits down with OpenRouter’s Alex Atallah and Replit founder and CEO Amjad Masad to discuss why the future of AI may look less like one…
- The a16z Show
Why AI Agents Can Beat the Incumbents
a16z’s Seema Amble and Elena Burger sit down with Lio co-founder and CEO Vladimir Keil to ask where AI-native startups have an advantage when incumbent…
- The a16z Show
Rebuilding the Internet for Privacy | Barrett Lyon on DoxxNet
a16z’s Joel de la Garza sits down with DoxxNet founder Barrett Lyon to discuss what it would take to rebuild the internet around privacy, direct communication…
- The a16z Show
The $1 Trillion AI Buildout | State of Markets
a16z’s David George, Sarah Wang, Alex Immerman, and Santiago Rodriguez unpack 25 key charts from the latest State of Markets presentation, from the scale of…
- The a16z Show
The Personal Agent Race Is Here | Anish Acharya & David Pawlan
a16z General Partner Anish Acharya sits down with Assistant Benchmark creator David Pawlan to unpack the sudden explosion of personal AI agents and what it…
- The a16z Show
AI Can Write Code. Why Isn’t Software Better?
a16z’s Ben Horowitz and Martin Casado sit down with TypeSafe AI founder Diogo Almeida to ask a simple question: AI has become remarkably capable, so where is…
- The a16z Show
Building a Team at AI Speed | Harvey’s Maggie Landers
a16z’s Katie Kirsch sits down with Harvey VP of Talent Maggie Landers to discuss what happens inside a company growing at AI speed, and how you preserve…
- The a16z Show
Aaron Levie, Steven Sinofsky & Martin Casado: How Do You Secure a World of AI Agents?
Erik Torenberg sits down with Box CEO Aaron Levie, and a16z’s Martin Casado, and Steven Sinofsky to debate how the AI industry should think about safety…
- The a16z Show
The Reputation Graph of Silicon Valley | Introducing Cosign
a16z’s Erik Torenberg sits down with Josh Elman, Olivia Moore, and David Booth to introduce Cosign, a new product built around professional reputation and the…
- The a16z Show
The Case Against an AI Pause | Eddy Lazzarin
a16z crypto General Partner Eddy Lazzarin joins Theo Jaffee on MTS to debate the increasingly prominent calls to slow AI development and whether the current…
- The a16z Show
Amjad Masad on Rethinking College for the AI Era
Erik Torenberg sits down with Replit founder and CEO Amjad Masad and Horowitz and Andreessen Academy co-founder and CEO Gagan Biyani to ask what education…
- The a16z Show
Why a16z is Building a New School for the AI Era | Ben Horowitz
Ben Horowitz and Erik Torenberg sit down with Gagan Biyani to introduce the Horowitz and Andreessen Academy and discuss a bigger question: what should…
- The a16z Show
AI Safety Language Is Destroying the Debate | Steven Sinofsky
a16z Board Partner and former Microsoft Windows president Steven Sinofsky joins Theo Jaffee and Sofia Puccini on MTS to argue that the language we use to…
- The a16z Show
Nas, Grandmaster Caz, Steve Stoute & Ben Horowitz on Paying Hip-Hop’s Pioneers Their Due
Ben Horowitz and Erik Torenberg sit down with Nas, Grandmaster Caz, and Steve Stoute for a conversation about the Paid in Full Foundation and its mission to…
- The a16z Show
What Makes a Consumer AI Product Stick? | Josh Elman
a16z Partner Josh Elman joins Ollie Forsyth on New Economies to discuss the next wave of consumer AI and what separates a product people try once from one that…
- The a16z Show
Databricks CEO on AI Pacing, Cyber Risk, and the Enterprise
Databricks co-founder and CEO Ali Ghodsi joins a16z General Partners Martin Casado and Sarah Wang for a conversation about AI risk, recursive self-improvement…
- The a16z Show
The Next Frontier of AI Video Is Control
a16z General Partner Jennifer Li sits down with fal co-founder Gorkem Yurtseven and Head of Engineering Batuhan Taskaya to discuss what changes when generative…
- The a16z Show
The AI-Native CRM
a16z’s Alex Rampell and Joe Schmidt sit down with Lightfield co-founder and CEO Keith Peiris to discuss what it takes to rethink the CRM for an AI-native…
- The a16z Show
The Age of Body Futurism | Ruby Justice Thelot
Elena Burger sits down with academic and cyber ethnographer Ruby Justice Thelot to explore the increasingly blurry line between internet culture and the real…
- The a16z Show
Greg Brockman on Why OpenAI Says We’re Entering the AGI Era
Ben Horowitz and Erik Torenberg sit down with OpenAI co-founder and President Greg Brockman to discuss why he believes AI has entered a new phase, what…
- The a16z Show
World Models, Robotics, and the Future of 3D AI
World Labs co-founder Justin Johnson joins MTS hosts Theo Jaffee and Sofia Puccini to discuss Atlas, World Labs’ latest world model, and the broader case for…
- The a16z Show
Why Companies Are Becoming a Series of Loops | Anish Acharya on Lenny’s Podcast
a16z General Partner Anish Acharya joins Lenny Rachitsky on Lenny’s Podcast to discuss why fears of an AI-driven “permanent underclass” may be misplaced, how…
- The a16z Show
What It Takes to Build a Startup | Andrew Chen & Matt Perault
a16z’s Matt Perault sits down with General Partner and Speedrun lead Andrew Chen on the a16z AI Policy Brief to explore what “Little Tech” actually looks like…
- The a16z Show
How AI Is Rewriting the Power Law of Venture Capital
a16z’s Jen Kha and David George sit down with Accolade Partners’ Aram Verdiyan to discuss how AI is changing the power law of technology investing, why the…
- The a16z Show
Who Grades the AI Models? | Ben Horowitz & Rayan Krishnan
a16z’s Erik Torenberg, Ben Horowitz, and Jennifer Li sit down with Vals founder and CEO Rayan Krishnan to discuss one of AI’s increasingly difficult problems…
- The a16z Show
OpenAI Researchers on the Future of Mathematical Reasoning
a16z Infra Partner Lisha Li sits down with OpenAI mathematicians Mehtaab Sawhney and Mark Sellke to discuss how quickly AI’s mathematical capabilities are…
- The a16z Show
Can Open Source Keep AI Power From Concentrating?
MTS host Sophia Dew visits the Open Source AI Summit in San Francisco to ask researchers and founders across the AI stack a central question: can open source…