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Training Data
Join us as we train our neural nets on the theme of the century: AI. Sonya Huang, Pat Grady and more Sequoia Capital partners host conversations with leading AI builders and researchers to ask critical questions and develop a deeper understanding of the evolving technologies—and their implications for technology, business and society. The content of this podcast does not constitute investment advice, an offer to provide investment advisory services, or an offer to sell or solicitation of an…
Episodes
Training DataA Model For Everyone: How Ronak From Trajectory Is Building Products For Continual Learning
Today’s agents are stuck in what Ronak Malde calls “pseudo continual learning”: intelligent, but updated in offline batches, like a paper road map you can’t…
Training DataEuropean Defense Sovereignty Starts in the Factory: Stark’s Uwe Horstmann and Johannes Schaback
Two years after its founding, Stark has roughly 700 employees and strike drones in the field in Ukraine. CEO Uwe Horstmann and CTO Johannes Schaback argue that…
Training DataInside the Robot Data Factory: Mecka's Josh Gao on Sensorizing Humans to Train Robots
Robotics never got the internet's gift of free training data, so someone has to manufacture it. Josh Gao, founder and CEO of Mecka AI, runs one of the largest…
Training DataDavid Silver and Lasse Espeholt of Ineffable Intelligence: A Superlearner for the Age of Experience
David Silver spent two years building AlphaGo on human data. When he removed human data altogether building AlphaGo Zero, the AI surpassed AlphaGo in under two…
Training DataGoogle's AI Infrastructure Chief, Amin Vahdat, on the Physics & Economics of Frontier AI
At 100,000-accelerator scale, something fails multiple times an hour, which is why Google's Chief Technologist for AI Infrastructure Amin Vahdat thinks FLOPS…
Training DataBox's Aaron Levie: On Reinventing Yourself in the AI Age and Enterprise Diffusion
Starting a company is hard. Reinventing your company for AI as a public company with quarterly earnings results is even harder. Aaron Levie has pulled off the…
Training DataMaking Cities Awesome: Peregrine’s Nick Noone & Ben Rudolph
Most public safety technology companies grow by collecting more data. Peregrine inverted the model: no sensors, no new data, a business built on connecting the…
Training DataParallel’s Parag Agrawal: Building a New Web for AI Agents
Parag Agrawal is making a bet that goes against two decades of web search: agents will query the web a thousand times more than humans ever have, and the…
Training DataRich Sutton and Khurram Javed: Why AI Models Stop Learning, and How to Start It Again
Rich Sutton, who helped pioneer reinforcement learning and wrote the seminal AI essay The Bitter Lesson, has now cofounded Oak Lab with his former student…
Training DataChai Discovery's Bitter Lesson: Drug Design Is Another Scaling Problem
Most people treat biology as a bespoke, messy science. Josh Meier and Matt McPartlon, co-founders of Chai Discovery, treat it as an engineering problem. They…
Training DataBuilding the Automated AGI Lab: Core Automation's Jerry Tworek and Rohan Anil
Jerry Tworek led reasoning at OpenAI, convinced that scaling reinforcement learning was the path to AGI. Rohan Anil co-led Gemini pre-training and built the…
Training DataFactory's Matan Grinberg: The Coming ‘Dark Factory’ Where Software Builds Itself
Factory started building fully autonomous coding agents in April 2023, two years before enterprises were ready. Matan Grinberg now says this is…
Training DataAnthropic's Katelyn Lesse & Angela Jiang: Building an Ecosystem, not a Walled Garden
Katelyn Lesse and Angela Jiang lead the team building Anthropic's developer platform - the layer that both outside builders and Anthropic's own products run on…
Training DataInside Zipline's Autonomous System: 140M Miles, Zero Incidents
The largest commercial autonomous system on earth isn't a robotaxi fleet — it's Zipline, which has flown 140 million autonomous miles with zero safety…
Training DataWhy Hardware-Software Co-Design Is AI's Real 100x: Dylan Patel of SemiAnalysis
Dylan Patel, founder of SemiAnalysis, argues the biggest gains in AI don't come from faster chips, they come from software-hardware co-design. Optimizing the…
Training DataMemory and Continual Learning: Engram's Dan Biderman and Jessy Lin
Dan Biderman and Jessy Lin, co-founders of Engram, are building a neolab around memory and continual learning, which they call two sides of the same coin…
Training DataSimulating Humans at Scale: Simile's Joon Sung Park
The race to build superintelligence is producing models that keep getting better at objective problems, but not at behaving like actual people. Joon Sung Park…
Training DataGoogle DeepMind's Logan Kilpatrick: Why the Model Eats the Harness
The entire startup ecosystem is racing to build agent harnesses. Logan Kilpatrick, who leads Google AI Studio and the Gemini API, argues that scramble has a…
Training DataLIVE: Jensen Huang on Building the Dynamo of the Intelligence Age
Jensen Huang, founder and CEO of NVIDIA, makes the case that computing is undergoing its biggest shift in 60 years: from retrieval, where data centers store…
Training DataKnowing What Your Customers Want, All the Time: Listen Labs' Alfred Wahlforss
Alfred Wahlforss, co-founder and CEO of Listen Labs, is building an AI agent that interviews your customers at a scale no focus group ever could—thousands of…
Training DataHow Cursor Trained Composer on Fireworks: Distributed Infrastructure for High-Performance RL
Cursor's Federico Cassano and Fireworks' Dmytro Dzhulgakov explain how they collaborated to build Composer as a specialized foundation model. The core insight…
Training DataRebuilding IT From the Ground Up for the AI Age: Serval's Jake Stauch
Jake Stauch, founder and CEO of Serval, is building a ServiceNow for the AI era. His most contrarian bet is that the product should look like boring old…
Training DataSuno's Mikey Shulman: Everyone Can Make Music Now
Most music platforms assume you're a listener. On Suno, 90% of daily users make something. Founder and CEO Mikey Shulman explains why that flips the model: the…
Training DataElevenLabs' Mati Staniszewski: How Voice Becomes the Interface for Everything
Mati Staniszewski, co-founder and CEO of ElevenLabs, joins Sequoia partner Andrew Reed at AI Ascent 2026 to talk about how a four-year-old company built a…
Training DataAnthropic's Boris Cherny: Coding's Printing Press Moment
Boris Cherny, creator of Claude Code at Anthropic, joins Sequoia partner Lauren Reeder at AI Ascent 2026 to talk about where coding goes from here. He explains…
Training DataWaymo's Dmitri Dolgov: 20 Million Rides and the Road to Full Autonomy
Dmitri Dolgov, co-CEO of Waymo, joins Sequoia partner Konstantine Buhler at AI Ascent 2026 to talk about the 20-year arc from the DARPA Grand Challenge to…
Training DataOpenAI's Greg Brockman: Why Human Attention Is the New Bottleneck
Greg Brockman, co-founder and president of OpenAI, joins Sequoia partner Alfred Lin at AI Ascent 2026 for a conversation that spans the full OpenAI stack. He…
Training DataDemis Hassabis on Building DeepMind, AlphaFold, and the Final Stretch to AGI
Demis Hassabis, co-founder and CEO of Google DeepMind and 2024 Nobel laureate in chemistry for AlphaFold, joins Sequoia partner Konstantine Buhler at AI Ascent…
Training DataAndrej Karpathy: From Vibe Coding to Agentic Engineering
Andrej Karpathy (co-founder of OpenAI, former head of AI at Tesla, and now founder of Eureka Labs) talks with Sequoia partner Stephanie Zhan at AI Ascent 2026…
Training DataFrom SEO to Agent-Led Growth: Profound’s James Cadwallader
James Cadwallader, co-founder and CEO of Profound, makes the case that we are living through the biggest platform shift in marketing history. The front door of…
Training DataHow Autonomous Labs Will Transform Scientific Research: Ginkgo Bioworks’ Jason Kelly
Jason Kelly founded Ginkgo Bioworks in 2008 with a simple but radical idea: DNA is code, and cells are programmable. Sixteen years later, AI is finally making…
Training DataGreetings, Earthlings: Philip Johnston of Starcloud on Data Centers in Space
Philip Johnston, founder and CEO of Starcloud, explains why space will become the primary location for AI compute infrastructure within the next decade. After…
Training DataPhysics Gets a Vote: Nominal Cofounders on Hardware Development in an AI World
Nominal’s cofounders (Cameron McCord, Jason Hoch and Bryce Strauss) realized that the new age of reindustrialization requires a new approach to hardware…
Training DataBuilding the GitHub for RL Environments: Prime Intellect's Will Brown & Johannes Hagemann
Will Brown and Johannes Hagemann of Prime Intellect discuss the shift from static prompting to "environment-based" AI development, and their Environments Hub…
Training DataWhat’s the Future of Vertical SaaS in an AGI World? Jamie Cuffe, CEO of Pace
Jamie Cuffe is solving one of AI's hardest problems: getting conservative, regulated industries to trust autonomous agents with mission-critical work. At Pace…
Training DataMaking the Case for the Terminal as AI's Workbench: Warp’s Zach Lloyd
Zach Lloyd built Warp to modernize the terminal for professional developers, but the rise of coding agents transformed his company's trajectory. He discusses…
Training DataContext Engineering Our Way to Long-Horizon Agents: LangChain’s Harrison Chase
Harrison Chase, cofounder of LangChain and pioneer of AI agent frameworks, discusses the emergence of long-horizon agents that can work autonomously for…
Training DataHow Ricursive Intelligence’s Founders are Using AI to Shape The Future of Chip Design
Anna Goldie and Azalia Mirhoseini created AlphaChip at Google, using AI to design four generations of TPUs and reducing chip floor planning from months to…
Training DataTraining General Robots for Any Task: Physical Intelligence’s Karol Hausman and Tobi Springenberg
Physical Intelligence’s Karol Hausman and Tobi Springenberg believe that robotics has been held back not by hardware limitations, but by an intelligence…
Training DataWhy the Next AI Revolution Will Happen Off-Screen: Samsara CEO Sanjit Biswas
Sanjit Biswas is one of the rare founders who has scaled AI in the physical world – first with Meraki, and now with Samsara, a $20B+ public company with…
Training DataThe Rise of Generative Media: fal's Bet on Video, Infrastructure, and Speed
fal is building the infrastructure layer for the generative media boom. In this episode, founders Gorkem Yurtseven, Burkay Gur, and Head of Engineering Batuhan…
Training DataWhy IDEs Won't Die in the Age of AI Coding: Zed Founder Nathan Sobo
Nathan Sobo has spent nearly two decades pursuing one goal: building an IDE that combines the power of full-featured tools like JetBrains with the…
Training DataHow End-to-End Learning Created Autonomous Driving 2.0: Wayve CEO Alex Kendall
Alex Kendall founded Wayve in 2017 with a contrarian vision: replace the hand-engineered autonomous vehicle stack with end-to-end deep learning. While AV 1.0…
Training DataHow Google’s Nano Banana Achieved Breakthrough Character Consistency
When Google launched Nano Banana, it instantly became a global phenomenon, introducing an image model that finally made it possible for people to see…
Training DataOpenAI Sora 2 Team: How Generative Video Will Unlock Creativity and World Models
The OpenAI Sora 2 team (Bill Peebles, Thomas Dimson, Rohan Sahai) discuss how they compressed filmmaking from months to days, enabling anyone to create…
Training DataNvidia CTO Michael Kagan: Scaling Beyond Moore's Law to Million-GPU Clusters
Recorded live at Sequoia’s Europe100 event: Michael Kagan, co-founder of Mellanox and CTO of Nvidia, explains how the $7 billion Mellanox acquisition helped…
Training DataSecuring the AI Frontier: Irregular Co-founder Dan Lahav
Irregular co-founder Dan Lahav is redefining what cybersecurity means in the age of autonomous AI. Working closely with OpenAI, Anthropic, and Google DeepMind…
Training DataWhy AI Will Transform Customer Experience: Cresta CEO Ping Wu and Sequoia’s Doug Leone
Ping Wu built Google's contact center business before becoming CEO of Cresta, where he's pioneering a unique approach to contact center transformation. Rather…
Training DataBlock CTO Dhanji Prasanna: Building the AI-First Enterprise with Goose, their Open Source Agent
As CTO of Block, Dhanji Prasanna has overseen a dramatic enterprise AI transformation, with engineers saving 8-10 hours a week through AI automation. Block’s…
Training DataWhy Businesses Are Rejecting the AI They’ve Asked For: Agency CEO Elias Torres
Elias Torres has been building AI systems since 1999, from chatbots at IBM to co-founding Drift and now Agency. He believes businesses are caught in an…
Training DataBuilding the "App Store" for Robots: Hugging Face's Thomas Wolf on Physical AI
Thomas Wolf, co-founder and Chief Science Officer of Hugging Face, explains how his company is applying the same community-driven approach that made…
Training DataDeal Velocity, Not Billable Hours: How Crosby Uses AI to Redefine Legal Contracting
Ryan Daniels and John Sarihan are reimagining legal services by building Crosby, an AI-powered law firm that focuses on contract negotiations to start. Rather…
Training Datan8n CEO Jan Oberhauser on Building the Universal AI Automation Layer
When the AI wave hit, n8n founder Jan Oberhauser faced a critical choice: become irrelevant or become indispensable. He chose the latter, transforming n8n from…
Training DataScaling the ‘Cursor for Slides’ to $50M ARR: Gamma founder Jon Noronha
Before ChatGPT made AI mainstream, John Noronha was building Gamma with a simple insight: everyone hates making slides but needs visual communication for…
Training DataDelphi’s Dara Ladjevardian: How AI Digital Minds Can Scale Human Connection
Dara Ladjevardian, founder and CEO of Delphi, is creating digital minds that allow people to scale their thoughts and availability without replacing human…
Training DataVercel CEO Guillermo Rauch: Building the Generative Web with AI
Vercel CEO Guillermo Rauch has spent years obsessing over reducing the friction between having an idea and getting it online. Now with AI, he's achieving…
Training DataOpenAI’s IMO Team on Why Models Are Finally Solving Elite-Level Math
In just two months, a scrappy three-person team at OpenAI sprinted to fulfill what the entire AI field has been chasing for years—gold-level performance on the…
Training DataOpenAI Just Released ChatGPT Agent, Its Most Powerful Agent Yet
Isa Fulford, Casey Chu, and Edward Sun from OpenAI's ChatGPT agent team reveal how they combined Deep Research and Operator into a single, powerful AI agent…
Training DataDeepMind's Pushmeet Kohli on AI's Scientific Revolution
Pushmeet Kohli leads AI for Science at DeepMind, where his team has created AlphaEvolve, an AI system that discovers entirely new algorithms and proves…
Training DataMapping the Mind of a Neural Net: Goodfire’s Eric Ho on the Future of Interpretability
Eric Ho is building Goodfire to solve one of AI’s most critical challenges: understanding what’s actually happening inside neural networks. His team is…