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Pharma 51: Inflammatory Bowel Disease - When Defence Becomes Damage

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This episode explores inflammatory bowel disease as the pharmacology of misdirected defence. In ulcerative colitis and Crohn’s disease, immune mechanisms designed to protect the intestinal barrier instead sustain injury over time. We examine cytokine signalling, epithelial integrity, microbiome interaction, and immune tolerance to understand why IBD is …

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