Latest / Your Daily Dose / WHAT IS THE STORY WITH PEPTIDES
Transcript
- 0:00Speaker 1: I'm sure a lot of you have had questions about peptides.
- 0:03Speaker 1: What are they?
- 0:05Speaker 2: It's a hot topic right now. BPC-157 and a number
- 0:11Speaker 2: of other peptides. We're going to get into how they
- 0:14Speaker 2: help with muscle, weight, and anti-aging. So we're going to
- 0:18Speaker 2: take a look at that.
- 0:18Speaker 1: Stay tuned. Hi, and welcome to Health Talk with Dr. Len,
- 0:21Speaker 1: your daily dose. The information you hear on this show
- 0:24Speaker 1: is informational. It's not meant to diagnose or treat any disease.
- 0:29Speaker 2: Any kind of Complete health conditions must be checked out
- 0:33Speaker 2: and discussed with your primary care physician.
- 0:36Speaker 1: Get ready for the good news of the day. God
- 0:39Speaker 1: bless you folks. And here is Dr.
- 0:42Speaker 2: Lent. Our daily devotional today comes from the book of
- 0:45Speaker 2: Isaiah chapter 54. I am always available to you. Once
- 0:50Speaker 2: you have trusted me as your Savior, I never distance
- 0:53Speaker 2: myself from you. Sometimes you may feel distant from me.
- 0:57Speaker 2: recognize that as feeling, do not confuse it with reality.
- 1:01Speaker 2: The Bible is full of my promises to be with
- 1:03Speaker 2: you always. As I assured Jacob when he was journeying
- 1:07Speaker 2: away from home into unknown places, I am with you
- 1:10Speaker 2: and will watch over you wherever you go. My last
- 1:13Speaker 2: recorded promise to my followers was this, surely I am
- 1:17Speaker 2: with you always to the very end of the age.
- 1:21Speaker 2: Let these assurances of my continual presence fill you with
- 1:25Speaker 2: joy and peace. No matter what you may lose in
- 1:28Speaker 2: this life, you can never lose your relationship with me.
- 1:32Speaker 2: Stay tuned.
- 1:49Speaker 3: Thank you. Thank you. 7 to 7.
- 2:50Speaker 2: 916-4215 to reach me off air. Peptide research began by
- 2:55Speaker 2: mimicking naturally occurring peptides before shifting to designing labs. They
- 3:01Speaker 2: made peptides with specific benefits. Peptides aren't new. They're naturally
- 3:06Speaker 2: produced by our body with a myriad of effects. For decades,
- 3:10Speaker 2: scientists have been studying and using them in medicine. Now
- 3:13Speaker 2: these small but powerful molecules are receiving a surge in
- 3:16Speaker 2: attention as potential tools for everything from muscle recovery and
- 3:19Speaker 2: weight management to healthier skin and age-related conditions. They are
- 3:24Speaker 2: short chains of amino acids, the same building blocks that
- 3:27Speaker 2: make up proteins, and they occur naturally throughout the body.
- 3:31Speaker 1: And in many foods, including meat, beans, lentils, wheat, and seafood.
- 3:43Speaker 3: Sorry.
- 3:49Speaker 1: Can't even hang up on that.
- 3:51Speaker 2: Peptide products started with scientists mimicking peptides found in our
- 3:54Speaker 2: body and in nature before progressing to designing peptides in
- 3:58Speaker 2: a lab with specific desirable benefits. A common misconception is
- 4:03Speaker 2: that peptides are one single thing.
- 4:07Speaker 1: In reality, the term covers a wide spectrum of products.
- 4:11Speaker 1: Can I highlight that in yellow, right? They are not
- 4:14Speaker 1: one single thing.
- 4:17Speaker 2: Peptide drugs, for example, include insulin, GLP-1 receptor agonists, calcitonin, oxytocin,
- 4:26Speaker 2: and certain fertility medications and several cancer therapies. Peptides are
- 4:31Speaker 2: also widely used as ingredients in skin care products and
- 4:33Speaker 2: marketed as supplements to support muscle growth, exercise recovery, weight management,
- 4:38Speaker 2: and healthy aging. There's also many experimental or investigational peptides,
- 4:43Speaker 2: such as BPC-157.
- 4:45Speaker 1: A popular regenerative peptide.
- 4:47Speaker 2: These products are often sold online with claims that exceed
- 4:50Speaker 2: the available evidence or without appropriate medical oversight. And like
- 4:55Speaker 2: many conventional medicines that introduce compounds designed.
- 4:58Speaker 1: To block or alter biological.
- 5:00Speaker 2: Pathways, peptide medicines work by mimicking the body's own signaling molecules.
- 5:07Speaker 1: Again, highlighted in orange.
- 5:11Speaker 2: Using semiglutide and terzepatide as examples, Andrea Colon, a licensed
- 5:16Speaker 2: naturopathic medical doctor and founder of Reclaim Integrative Medicine, says
- 5:20Speaker 2: they copy a signal your body already uses to manage
- 5:23Speaker 2: blood sugar and appetite. So they work with your biology
- 5:26Speaker 2: instead of overriding it.
- 5:29Speaker 1: Dr.
- 5:29Speaker 2: Modi, a pharmaceutical regulatory affairs expert with more than 20
- 5:32Speaker 2: years experience working on products that are regulated by the FDA,
- 5:36Speaker 2: said peptides differ from traditional drugs mainly in size and
- 5:40Speaker 2: how precisely they act.
- 5:43Speaker 1: Highlighted in orange.
- 5:47Speaker 2: They are more complex and often act specifically on certain
- 5:50Speaker 2: biological pathways, which can make them highly effective in the
- 5:53Speaker 2: right situations.
- 5:55Speaker 1: That precision comes with trade-offs, however. Peptides tend to break down.
- 5:58Speaker 2: Easily in the digestive system, which is why they often
- 6:02Speaker 2: are injected rather than taken as pills.
- 6:05Speaker 1: They can also be more expensive to produce, and their
- 6:07Speaker 1: absorption can vary.
- 6:09Speaker 2: Peptide products are more expensive because they are often more
- 6:12Speaker 2: complex to manufacture, requiring precise assembly of amino acids.
- 6:16Speaker 1: Extensive purification, and rigorous quality.
- 6:21Speaker 3: Testing.
- 6:22Speaker 2: Many peptides are also less stable than traditional drugs and
- 6:25Speaker 2: require specialized storage and packaging. Peptide products span a wide
- 6:32Speaker 2: range of use with significant variations in how well-studied they are.
- 6:37Speaker 2: GLP-1-based therapies, semiglutide-tosepidide, mimic natural gut hormones that regulate blood
- 6:42Speaker 2: sugar and appetite.
- 6:44Speaker 1: Insulin analogs.
- 6:45Speaker 2: The discovery of insulin in the early 20s marked one
- 6:48Speaker 2: of the first major breakthroughs in peptide hormone research. Teraeparatide
- 6:56Speaker 2: and abaloparatide. These medications are used to treat osteoporosis, particularly
- 7:02Speaker 2: in patients with high risk of fractures, such as postmenopausal women.
- 7:05Speaker 2: They mimic parathyroid hormone activity to stimulate new bone formation.
- 7:10Speaker 1: That's interesting. I didn't know that.
- 7:14Speaker 2: Cosmetic peptides are widely used in skin care, but their
- 7:16Speaker 2: clinical effects can vary depending on formulation and concentration. So,
- 7:23Speaker 2: palmitoyl peptides, commonly used as anti-aging products. These are amino
- 7:26Speaker 2: acid chains bound to a fatty acid. Copper tripeptide, used
- 7:32Speaker 2: in anti-aging and wound healing products. Acetyl hexapeptide 8, sometimes
- 7:38Speaker 2: marketed in Botox-like ingredients because it may soften expression lines.
- 7:43Speaker 2: brightening peptides, typically used in cosmetic products. Well, these products
- 7:48Speaker 2: show promising benefits for other researchers needed to establish their
- 7:51Speaker 2: safety and long-term effects. Collagen peptides, those are the most
- 7:55Speaker 2: widely used products in this group. Research suggests possible benefits
- 7:59Speaker 2: for joint comfort and function, as well as some support
- 8:01Speaker 2: for body composition. Plant protein-derived peptides are found in soy, seeds,
- 8:07Speaker 2: tree nuts, and lupin. chlorella, and spirulina fractions derived from
- 8:11Speaker 2: the nutrient-rich microalgae. These peptides have been studied for antioxidant, anti-inflammatory.
- 8:17Speaker 1: And immune-supporting properties.
- 8:21Speaker 2: Peptides are a group of off-label experimental peptides commonly marketed
- 8:25Speaker 2: with goals such as repair, muscle growth, and fat loss. BPC-157,
- 8:29Speaker 2: body protection compound 157, marketed for tissue repair, muscle recovery,
- 8:35Speaker 2: chronic pain, and gut health. TB500, synthetic thymocin beta-4 fragment.
- 8:41Speaker 2: This peptide is marketed for soft tissue repair, reducing inflammation,
- 8:45Speaker 2: and enhancing athletic recovery. CJC 1295. These peptides are marketed
- 8:51Speaker 2: for muscle gain, fat loss, exercise recovery, better sleep, healthy
- 8:55Speaker 2: skin aging. There's no single rule for how peptides should
- 8:58Speaker 2: be used. It depends entirely on the specific products. They
- 9:01Speaker 2: can be delivered through several routes, oral, nasal, injectable, and topical.
- 9:05Speaker 2: Injectable are currently the most common route. For oral peptides,
- 9:10Speaker 2: research has made advancements in drug delivery technology, including polymer
- 9:13Speaker 2: nanoproducts and microneedles. Nasal delivery allows peptides to be absorbed
- 9:18Speaker 2: through the nasal lining and may use direct nose-to-brain pathway. Interesting.
- 9:26Speaker 2: Topical peptide products are commonly used in skin care for
- 9:31Speaker 2: the duration of usage. Christopher Shade, a longevity expert as
- 9:34Speaker 2: a doctor in environmental chemistry, said there's no universal formula.
- 9:38Speaker 2: Writers typically weigh the condition being treated and how benefits
- 9:42Speaker 2: change over time. The monitoring required during peptide therapy may
- 9:46Speaker 2: include tracking blood glucose, kidney and liver function, hormonal levels
- 9:50Speaker 2: such as IGF-1 and thyroid hormone, blood pressure, and inflammatory markers.
- 9:56Speaker 1: This is another one that's very important. Peptides are not established. shortcut,
- 10:01Speaker 1: and they don't work in a vacuum.
- 10:04Speaker 2: Colon emphasizes that peptides are most effective when paired with
- 10:08Speaker 2: healthy lifestyle habits, not as a replacement for them. If
- 10:14Speaker 2: the basics are a mess, peptide.
- 10:16Speaker 1: Is very little to work with.
- 10:19Speaker 2: Regulatory agents such as the FDA have warned that many
- 10:21Speaker 2: peptides sold online are not approved and may carry safety
- 10:24Speaker 2: risks tied to poor quality, improving effectiveness, and misleading marketing claims.
- 10:28Speaker 2: A June survey of more than 500 U.S. physicians found
- 10:31Speaker 2: that 48% reported patients disclosing use of a non-FDA approved
- 10:36Speaker 2: peptide within the last year. Dr. Modi said that the
- 10:40Speaker 2: peptides simply have not gone through what the testing of
- 10:42Speaker 2: the FDA requires. Approval demands well-designed clinical trials, strict manufacturing controls,
- 10:50Speaker 2: and solid proof in safety and effectiveness. In many cases,
- 10:54Speaker 2: not approved doesn't mean proven dangerous.
- 10:57Speaker 1: It means no one paid to test it. Highlighted in orange.
- 11:03Speaker 2: Catches, it also means no one has proven it safe,
- 11:06Speaker 2: or it even works. So, practical checklist of red flags.
- 11:12Speaker 2: No real prescription, no licensed clinician involved. direct consumer shipping
- 11:18Speaker 2: with no pharmacy involved, no proof of third-party testing, prices
- 11:22Speaker 2: that seem too good to be true, a single product
- 11:24Speaker 2: claiming to fix many unrelated problems, big promises with no
- 11:29Speaker 2: risks listed. The field of therapeutic peptides started with natural hormones.
- 11:35Speaker 2: To make a real change, the answer may ultimately lie
- 11:37Speaker 2: in our hands. As performant, optimizing physician Dr. Sean O'Mara
- 11:42Speaker 2: told the news, Previously, when he talked about GLP-1, man-made
- 11:46Speaker 2: molecules cannot duplicate the.
- 11:47Speaker 1: Elegance of the human body. There you go. Pretty cool.
- 11:53Speaker 2: Right now, we're working with BPC-157, like its effect.
- 11:57Speaker 1: If you need help with that, give me a call. 727-916-4215.
- 12:00Speaker 3: God bless.