Latest / WhiteBoard Medicine - Emergency And Critical Care
#217 Prothrombin Complex Concentrate (PCC) Explained | Components, Indications, Dosing, and Safety
Prothrombin Complex Concentrate (PCC) is a powerful, targeted coagulation therapy used in urgent bleeding and anticoagulation reversal. In this episode, we walk through what PCC is, when to use it, how to dose it, and what safety considerations matter most in real-world clinical practice. This audio-focused discussion covers: What Prothrombin Complex Concentrate (PCC) contains Common indications, including warfarin and vitamin K antagonist reversal Key differences between 3-factor and 4-factor PCC Practical dosing strategies Risks, contraindications, and thrombotic concerns How PCC compares…
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