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Unveiling Regenerative Skincare with The Science Behind DefenAge · Skin Anarchy

• 0:00
  SPEAKER_00: Hey guys, welcome back to another episode of Future Anarchy.
• 0:03
  SPEAKER_00: This is your host, Ekta, and I'm really excited about introducing the brand that we have here today.
• 0:08
  SPEAKER_00: They're really a brand that's been in the industry for a long time and they've seen all of the advancements and the great things that are always coming up in the beauty industry and have really kept up with it and have led the way and are still leading the way with many of their products.
• 0:22
  SPEAKER_00: So I'm very excited to be hosting Dr.
• 0:25
  SPEAKER_00: Angela Bowers and Marta Levy, who is the VP of Business Development.
• 0:29
  SPEAKER_00: So welcome, Dr.
• 0:30
  SPEAKER_00: Bowers and Marta.
• 0:31
  SPEAKER_00: I'm so excited to host both of you.
• 0:33
  SPEAKER_02: Thank you for having us.
• 0:35
  SPEAKER_00: Yeah, I'm really excited to talk about Deaf and Age.
• 0:37
  SPEAKER_00: That's the brand name for everyone listening.
• 0:39
  SPEAKER_00: Didn't mention it.
• 0:40
  SPEAKER_00: But Dr.
• 0:40
  SPEAKER_00: Bowers, I was wondering if you could get us started and just give us a little background on the brand and obviously your involvement with it.
• 0:46
  SPEAKER_00: I mean, I would love to learn from the medical perspective, you know, where the inspiration really stems for Deaf and Age and how it's been keeping up with this industry and just the journey overall.
• 0:57
  SPEAKER_02: Absolutely.
• 0:57
  SPEAKER_02: I've been in practice for 25 years now in Texas.
• 1:01
  SPEAKER_02: And from the very get-go, I've been very involved in the cosmetic and the dermatology that that was all starting and blooming when I was in my residency and getting out from like skin suiticals, vitamin C, and alpha hydroxy acids and so forth.
• 1:17
  SPEAKER_02: And of course, the whole industry has just completely bloomed and improved and progressed since then.
• 1:23
  SPEAKER_02: My hand with Dinage and how I got involved was basically at one of these cosmetic dermatology-focused meetings back in 2016 when I saw some of the studies presented and before and afters, and was just very impressed that we could actually put something on topically to stimulate our stem cells to create young skin.
• 1:45
  SPEAKER_02: And nothing like that had ever been even talked about in the marketplace.
• 1:49
  SPEAKER_02: At that point in time, we were just starting to learn about using stem cell technology for joints and repairing different parts of our aging bodies internally.
• 2:00
  SPEAKER_02: With the definage, we just have had extremely positive feedback from all of our patients that have used it since it's been about eight years now since we've incorporated it into our practice.
• 2:14
  SPEAKER_00: It's a really interesting brand to me because obviously, for what you just mentioned with the stem cell component, but also more importantly from what I've read, um the regenerative medicine component as well.
• 2:24
  SPEAKER_00: I mean, I think regenerative medicine is definitely having its glory days, you know, in the recent years.
• 2:30
  SPEAKER_00: I've definitely seen it, you know, come up more in academia and as well as clinical medicine.
• 2:36
  SPEAKER_00: You know, it's it's something that I think people are becoming more privy to and understanding more from a consumer perspective.
• 2:42
  SPEAKER_00: And I would love to learn more about it.
• 2:43
  SPEAKER_00: Marta, maybe you could tell us a little bit about how Definage kind of incorporates regenerative medicine in their approach.
• 2:49
  SPEAKER_01: Yes, thank you.
• 2:51
  SPEAKER_01: My background, um about 25 years as Dr.
• 2:54
  SPEAKER_01: Bowers in the industry, but on the business end, launching new technologies that have become leading brands.
• 3:00
  SPEAKER_01: And so my interest stemmed from approach by the scientist and marketing team at the time.
• 3:07
  SPEAKER_01: And because I know a lot of the thought leaders in the industry, they wanted me to help launch this brand.
• 3:12
  SPEAKER_01: But you know, skincare, I didn't think was could be anything really new and different.
• 3:18
  SPEAKER_01: And my relationships were used to me bringing them new technologies that you know brought something new to their practice that worked, etc.
• 3:26
  SPEAKER_01: But I just said, you know, I'll try it because the science behind it sounded so interesting to me.
• 3:31
  SPEAKER_01: My background's in science.
• 3:33
  SPEAKER_01: And so I just was trialing it.
• 3:34
  SPEAKER_01: It was my own colleagues that actually saw changes in my skin even in a month's time.
• 3:40
  SPEAKER_01: It took me probably a good three months to put my name behind the brand and uh never looked back.
• 3:46
  SPEAKER_01: Uh, super interesting.
• 3:48
  SPEAKER_01: So it's based on the defensive molecule, which is naturally occurring in our body.
• 3:55
  SPEAKER_01: It's released by our immune system at wounding, and it's going to wake up your very own dormant stem cells that created all the lineages of your skin and utero.
• 4:05
  SPEAKER_01: It's going to wake up those stem cells and just those, it's not going to go to any other cells in the body that have been working, you know, in the epidermis.
• 4:14
  SPEAKER_01: You know, that could be potentially more fragile cells, more prone to mutations.
• 4:18
  SPEAKER_01: These defensive molecules just wake up again, your very own dormant stem cells that have never worked your whole life to migrate out of sleeping and make brand new basal stem cell layers, brand new basal stem cells, ultimately new young keratinocytes.
• 4:35
  SPEAKER_01: So we don't have stem cells in the product.
• 4:37
  SPEAKER_01: We're just going to use your own body's resources, which is interesting.
• 4:42
  SPEAKER_01: And you know, with that we see so many different changes in the skin because we're truly making new younger cells.
• 4:49
  SPEAKER_01: As Dr.
• 4:50
  SPEAKER_01: Bowers was saying, you know, her patients see quick results and really all-encompassing anti-aging results.
• 4:58
  SPEAKER_01: And then because it was so new, clinicians like Dr.
• 5:01
  SPEAKER_01: Bowers, you know, that were interested, they said, but you know, hey, this is super interesting, but never heard of this, you know, where's your studies?
• 5:09
  SPEAKER_01: Where's your histology?
• 5:11
  SPEAKER_01: So I took a step back, and there was a multi-center placebo-controlled study published in 2018 in the JDD that really put definage on the map and really supported with clinical evidence.
• 5:25
  SPEAKER_01: And that was a super exciting time.
• 5:27
  SPEAKER_01: And now we have 30 plus clinical studies, but it all came about just to go backwards again.
• 5:32
  SPEAKER_01: Our scientist, Dr.
• 5:34
  SPEAKER_01: Nikolai Theravatz, regenerative medicine scientist working with stem cell therapies for different diseases.
• 5:40
  SPEAKER_01: He was looking at stem cell therapies to assist with diabetic patients because we know that clientele is wound healing compromised.
• 5:48
  SPEAKER_01: And he came up with the basic science about defenses, how they're involved with wound healing and LGR6 positive stem cells.
• 5:56
  SPEAKER_01: And that eventually led to the creation of the idea for a topical product for anti-aging.
• 6:02
  SPEAKER_00: That's so interesting to me.
• 6:03
  SPEAKER_00: And I love the approach because many times, as I'm sure both of you have seen, you know, in the in this industry, there's a lot of claims around stem cells and the usage of stem cells in products.
• 6:15
  SPEAKER_00: But I've never been able to really get behind them because anyone who understands molecular biology understands that it's not really using whole cells that's going to do the job.
• 6:26
  SPEAKER_00: It's really the signaling proteins and peptides that really work, you know, and the molecules that allow certain signaling processes to occur that allow the maturation of cells.
• 6:36
  SPEAKER_00: So this is a very novel approach.
• 6:38
  SPEAKER_00: And so my question really is me for Dr.
• 6:40
  SPEAKER_00: Bowers, you know, when it comes to utilizing the products and really getting the most out of them, do you recommend use for like daily care or is it also most beneficial like post-procedure care?
• 6:52
  SPEAKER_02: It's great for both.
• 6:53
  SPEAKER_02: So we recommend it as daily care, but it it does, I think, improve the outcome post-procedurally of when we do some of these.
• 7:02
  SPEAKER_02: Oh, whether it's microneedling or anything that just disrupt the epidermis and epidermis to stimulate new collagen production by repairing the skin.
• 7:13
  SPEAKER_02: If the stem cell is stimulated to create young skin, we're just it's like the eight in one serum by Definage is the fertilizer, and it just really kicks everything off.
• 7:24
  SPEAKER_02: So I use it in both capacities.
• 7:32
  SPEAKER_00: And you know, I I hear a lot of them, you know.
• 7:35
  SPEAKER_00: I think a lot of consumers do, where we're told, like, yeah, you know, you have to repair your skin barrier, but then on the other hand, you're told like the skin barrier is one of the toughest things to get through, you know, and to to really kind of penetrate.
• 7:48
  SPEAKER_02: Exactly.
• 7:48
  SPEAKER_00: Yeah, like that's where I'm I'm always a little confused about it.
• 7:51
  SPEAKER_00: I would love for you to kind of clarify that if you don't mind.
• 7:53
  SPEAKER_00: Like, you know, really what is the skin barrier and what should we know about it, just as consumers, you know, when we're dealing with trying to figure out like the products we should be purchasing, you know?
• 8:02
  SPEAKER_02: Yes, absolutely.
• 8:03
  SPEAKER_02: Well, I mean, skin barriers kind of like the skin cells made up of say a lot of little bricks, so the barriers that mortar can be disrupted by so many different things, whether it's just mechanically that we're doing too many scrubs or the exposure to the outdoors with wind and sun, genetically, we can be prone to have defects in our the glue basically of between the cells.
• 8:29
  SPEAKER_02: So there's a lot of, especially eczema, atopic dermatitis type patients.
• 8:34
  SPEAKER_02: There's a an actual genetic defect to really have the best glue between those skin cells.
• 8:40
  SPEAKER_02: So trying to keep the barrier just makes the skin feel more comfortable.
• 8:47
  SPEAKER_02: There's less inflammation.
• 8:48
  SPEAKER_02: That's the thing that I think has been so remarkable about definage is that you can use it on any skin type.
• 8:55
  SPEAKER_02: You can use it around the eyes, on top of the eyelids, you can go across the lips.
• 9:00
  SPEAKER_02: You're not going to be getting irritated from it.
• 9:03
  SPEAKER_02: Unlike basically almost all the other skincare products out there.
• 9:07
  SPEAKER_02: You know, what I tell most of my patients is that, you know, from like 25 years ago, at this point in time, we have there's a lot of great products on the market that really do help the skin, but we don't have anything like defonage.
• 9:20
  SPEAKER_02: Definage is the only one in its class to create our own young skin.
• 9:25
  SPEAKER_02: And it can be even utilized with some other modalities.
• 9:29
  SPEAKER_02: Um, so it's not kind of an all or nothing thing.
• 9:32
  SPEAKER_02: If a patient has a few things that they're enjoying using, I just add the definage on top of it.
• 9:37
  SPEAKER_02: It can be very synergistic.
• 9:38
  SPEAKER_00: That's interesting.
• 9:39
  SPEAKER_00: That's really interesting.
• 9:40
  SPEAKER_00: And I noticed there's a retinol alternative serum here, and I'm very curious about retinol, you know, not only obviously from like the clinical perspective, but also like from a marketing perspective.
• 9:51
  SPEAKER_00: I mean, Marta, maybe you can help us kind of work through this one because I think right now what I see a lot of is a lot of people are claiming that, you know, this is a great retinol alternative or this this ingredient or that ingredient, but no one's really talking about, you know, beyond the marketing, right?
• 10:07
  SPEAKER_00: Like it's almost like as if the science gets lost in the marketing.
• 10:11
  SPEAKER_00: And I'm just curious, you know, with definage, like how did you guys manage to stay above that, you know, and really stick to the science?
• 10:18
  SPEAKER_01: Yeah, so the eight in one bio serum is really the hero product of the whole line.
• 10:23
  SPEAKER_01: And we would call it a retinol alternative serum.
• 10:26
  SPEAKER_01: It has, you know, eight different serums.
• 10:28
  SPEAKER_01: So the retinol alternative is really the highest concentration of this um defensin molecule, alpha defensin 5, and it works in a whole different way than other ingredients, as Dr.
• 10:41
  SPEAKER_01: Bauer said.
• 10:42
  SPEAKER_01: It doesn't work via an inflammatory response.
• 10:45
  SPEAKER_01: And also, we do go a further step to make this defensin molecule very stable, the whole complex that's encapsulated in liposomes for very stable delivery, because we do need to get deep at the DE junction.
• 10:59
  SPEAKER_01: So we're incorporating this defensin molecule into liposomes and delivering it deep.
• 11:04
  SPEAKER_01: We really don't even care to put a cream on the skin.
• 11:06
  SPEAKER_01: We need to get to that target that we're going to wake up again, those LGR6 positive stem cells that sit at that DE junction.
• 11:14
  SPEAKER_01: So we've got, you know, so many other high-end performing ingredients in this 8-in-1 serum.
• 11:20
  SPEAKER_01: So the collagen serum is enhanced with beta defensin 3.
• 11:24
  SPEAKER_01: So that actually boosts the collagen, improves elasticity and firmness, helps improve sagging skin.
• 11:31
  SPEAKER_01: And then we also have niacinamide, very rich in niacinamide, vitamin B3, which soothes, hydrates, brightens the skin, helps improve the skin barrier function as well.
• 11:41
  SPEAKER_01: We also have HA serums in there, HAs for deep hydration, very high in moisturization components, also antioxidant serums, which is a blend of different antioxidants, including ergothionine, which helps combat the environmental damage that we're all exposed to and also has a brightening effect.
• 12:02
  SPEAKER_01: And we've got very strong anti-inflammatory.
• 12:05
  SPEAKER_01: So our calming serum is a fine blend of soothing and calming ingredients.
• 12:10
  SPEAKER_01: The common name for this ingredient is Lovina Puff, and it is known as a medical plant cortisome-free alternative, and it's the water-soluble form, one of the most active molecules that we find in green tea, black currant seed.
• 12:27
  SPEAKER_01: Really, we all know, you know, inflammation is a big cause of aging, so that really helps calm the skin and keep down inflammation.
• 12:34
  SPEAKER_01: We also have a fine blend of peptides, peptide serum, which includes palmatoil tripeptide 38, which targets critical aging, like uh smoothing wrinkles and refining the skin texture.
• 12:47
  SPEAKER_01: And the eighth is a DNA repair enzyme serum from Mediterranean Arabopsis, I believe is how you say it, uh, renowned for you know repairing common DNA damage.
• 12:58
  SPEAKER_01: So it's a really just super high and performing serum with the primary ingredients again, defensins and addition to you know other high-performing ingredients.
• 13:09
  SPEAKER_01: So that's going to really supercharge anything that you're doing, whether you're doing, you know, some laser treatments, microneedling, as Dr.
• 13:18
  SPEAKER_01: Bauer said, even if you're going for surgical procedures, if you can prep the skin before with the definage, you're only going to make the skin healthier, physically thicker, and your results will be much better and you will heal much faster.
• 13:32
  SPEAKER_00: That's so fascinating.
• 13:33
  SPEAKER_00: I think that's just such an interesting approach because you know, many times seeing products that are very like um single-target products.
• 13:41
  SPEAKER_00: And it one of my questions was always as a consumer, you know, where is the integration of all of these different principles coming together?
• 13:49
  SPEAKER_00: So, one of the questions I have, Dr.
• 13:51
  SPEAKER_00: Bowers, is trying to understand this idea of how important is is it for consumers to understand the use of things like antioxidants coupled with things that promote collagen production and you know, all of these different components working together?
• 14:04
  SPEAKER_00: Like how is that something that we should just think as the norm as consumers, or how should we approach skincare?
• 14:11
  SPEAKER_02: It's so complicated for our consumers now because of just the the pure marketing aspect.
• 14:17
  SPEAKER_02: And you know, I still will have patients come into my office that I've seen for years, and then they may go on a cruise or something, and they end up in the spa and then they buy, you know,$500 worth of these products that really aren't they're not gonna do near what Definage does, you know.
• 14:34
  SPEAKER_02: So that part is really kind of painful for me when I see patients spending money on products that are they're okay, they're not bad, but there's just so much better that they can do.
• 14:44
  SPEAKER_02: So it is very difficult for patients to really siphon through and know.
• 14:50
  SPEAKER_02: So that's I mean, I guess that's why I'm I'm thankful I'm in my field and we do try to educate our patients about that and seeing like what you're doing, trying to kind of get the word out.
• 14:59
  SPEAKER_02: So we're we're making the best use of our money and and time.
• 15:03
  SPEAKER_02: I mean, nobody has time to put eight different things on their stem, usually.
• 15:07
  SPEAKER_02: So, you know, I think a couple of points with that question, antioxidants and so forth, is you know, everything's so cumulative.
• 15:15
  SPEAKER_02: So just being careful with sun exposure, obviously, it's such a given.
• 15:20
  SPEAKER_02: Eating healthy, so just kind of having a high antioxidant diet, it's gonna help in general.
• 15:26
  SPEAKER_02: Postmenopausal patients, as we lose estrogen, some may not be on estrogen supplements, and then the skin ages even more dramatically when we're off of that.
• 15:36
  SPEAKER_02: I do see depanage really counteract that process postmenopausally, which is fantastic.
• 15:43
  SPEAKER_02: Most of them are not gonna be able to tolerate retinol or ret any type of retinoid.
• 15:48
  SPEAKER_02: Occasionally they can, depending on where they live, but it's gonna be so drying.
• 15:54
  SPEAKER_02: So it has been, I occasionally do combine it with some retinols, but it's one of those products where I tell my patients when I travel, I always take my deponage with me.
• 16:05
  SPEAKER_02: I might in my sunscreen, I might leave a few other little things behind if I'm kind of crunched on space, but I always make sure I kind of have that in my repertoire of skincare kind of all the time.
• 16:19
  SPEAKER_02: But with the deponage product, I think one thing that really struck me, Marty, you might be able to remember the date of when this study was published, but they there was a half face compared to study done where a fairly decent group of patients had microneedling done.
• 16:35
  SPEAKER_02: On half the face, they used the PRP, which is like that vampire facelift that basically you draw the blood, spin it down, put it on after, and then the other half they use deponage.
• 16:46
  SPEAKER_02: Well, the deponage side did outperform the PRP side, which makes sense because you're stimulating your own stem cell to actually work and do what it knows it's supposed to do, versus just trying to put on these extra growth factors from your blood that's spun down on top of the skin, where you're supposed to have a skin barrier intact.
• 17:06
  SPEAKER_02: So disrupting the skin barrier to try to help all of that, but that really was a I think a pivotal study for me to know that we can just use this topically and get even better results than trying to do the TRP method.
• 17:21
  SPEAKER_02: And it's more cost effective for patients.
• 17:23
  SPEAKER_02: In addition, not only just anti-aging and with the new collagen, elastin production, and the brand new skin cells that it produces, you can see a decrease in inflammation.
• 17:35
  SPEAKER_02: So my rosacea patients or other various skin disorders that have very sensitive skin, can tolerate hardly anything, do great with effinage.
• 17:47
  SPEAKER_02: I think it it really helps control their rosacea.
• 17:51
  SPEAKER_02: And that's something that I can kind of talk about, but it's certainly not a medical claim that deponage can.
• 17:57
  SPEAKER_02: This is just an observation that I've had over the years.
• 18:01
  SPEAKER_02: You know, myself, I even have a little bit of rosacea.
• 18:04
  SPEAKER_02: Once I started using deponage, it just, you know, the very little outbreak of that while I stay on it.
• 18:11
  SPEAKER_02: When you reference two plastic surgery, you know, the wound healing improves.
• 18:15
  SPEAKER_02: So any of the scars that you incur, they're gonna heal faster.
• 18:20
  SPEAKER_02: It's got these antimicrobial peptides properties to it.
• 18:24
  SPEAKER_02: So our patients that may even have atopic dermatitis and sensitive skin and might be prone to some other skin infections, this is gonna help prevent that.
• 18:34
  SPEAKER_00: That's so fascinating because I find burn wound healing to be really such an interesting field when it comes to understanding just how our skin not only like you know regenerates, but also like what the process is, right, of like the body responding to like excessive trauma.
• 18:52
  SPEAKER_00: And I guess like one of my biggest pain points when it comes to understanding just everyday trauma that we incur, like you know, through environment or through whatever we're doing to our skin, whether it's at-home procedures and whatnot, is is understanding how all of this fits in to this greater understanding.
• 19:09
  SPEAKER_00: So I guess one of the big things that comes up is inflamma aging.
• 19:13
  SPEAKER_00: And I would love, Dr.
• 19:14
  SPEAKER_00: Bowers, if you could kind of explain inflamma aging from this perspective of um defenses and understanding what they do in the overall picture of inflammation and what it leads to for our skin.
• 19:28
  SPEAKER_02: Right.
• 19:29
  SPEAKER_02: Yeah, that's a very hot topic.
• 19:31
  SPEAKER_02: It's such an interplay and a balance between, in some cases, we are trying to cause a tiny bit of inflammation in the skin with some of the procedures that we do in dermatology, and then try to get our own body's wound healing properties to then improve and make younger, stronger skin.
• 19:49
  SPEAKER_02: But if you go, if you flip and you inflame the skin too much, then you're kind of on the opposite side where you're going to cause more aging, different inflammatory mediators that are produced.
• 20:00
  SPEAKER_02: And you can see this even in patients that are undergoing chemotherapy or they have these chronic diseases like Crohn's or diabetes, different things where you have a kind of an underlying inflammatory blood system, if you will, their skin is going to age faster than someone that does not have that.
• 20:22
  SPEAKER_02: So that's where it comes in, just you know, trying to have an overall most a lot of patients are more in tune with this anyway, but overall healthy lifestyle where you're not drinking very much, you know, certainly alcohol really does not help the skin in any capacity.
• 20:37
  SPEAKER_02: Low stress, because that's going to be cause inflammation.
• 20:41
  SPEAKER_02: You know, just being kind to yourself and then you know, trying to protect it from the external stimuli that we're all exposed to between the sun and pollution and all those different factors.
• 20:53
  SPEAKER_00: Yeah.
• 20:54
  SPEAKER_00: No, it makes sense.
• 20:55
  SPEAKER_00: It really makes sense.
• 20:55
  SPEAKER_00: So it's a topic I think that doesn't get discussed too much either, is this idea of like what are we putting in our bodies, you know, that are really leading to more inflammation.
• 21:04
  SPEAKER_00: I mean, I think now they're focusing more on like the gut-skin axis, and you know, they're starting to, I think, bring this information, this knowledge out to like the masses and the consumers to understand that you know there is this huge link between what we consume and and how our skin reacts.
• 21:20
  SPEAKER_00: But there's definitely, I think, a lot more education uh that needs to be put out there.
• 21:26
  SPEAKER_00: So yeah, no, absolutely.
• 21:28
  SPEAKER_00: Absolutely.
• 21:29
  SPEAKER_00: I love Definage a lot.
• 21:30
  SPEAKER_00: I think the brand is just it's such a like pillar in the space because it really stands for what I believe to be true innovation in science, you know, uh in dermatology.
• 21:40
  SPEAKER_00: I mean, I think a lot of people want to apply scientific principles, but it's one thing to, you know, apply one component.
• 21:46
  SPEAKER_00: But then when you look at things from a more holistic viewpoint, a more broader viewpoint, you know, such as what we've discussed here, which is wound healing, that's a huge, huge accomplishment, you know, to be able to take those findings and apply them to some.
• 22:00
  SPEAKER_00: Something that can be used topically and used at home.
• 22:02
  SPEAKER_00: And so for all of our listeners, I know a lot of you always chime in asking for options.
• 22:06
  SPEAKER_00: A lot of post-procedure care questions we get, you know, in terms of what the best options are.
• 22:11
  SPEAKER_00: And I think this is a really heavy header.
• 22:13
  SPEAKER_00: So if any of you are looking for something that you can use daily or post-procedure, definitely check out Definage.
• 22:20
  SPEAKER_00: They have such great offerings.
• 22:21
  SPEAKER_00: I've used so many of your products.
• 22:23
  SPEAKER_00: And even I, we didn't get to talk about it, but there's a nail serum I really love.
• 22:27
  SPEAKER_00: Um, I had a really bad nail break um, you know, a month or two ago, and I was using the serum, and it literally healed within less than a week.
• 22:35
  SPEAKER_00: And I was so, you know, thrilled to see that because that never happens.
• 22:39
  SPEAKER_00: So there's just so many great products, and I think there's a lot that consumers can really get from the brand.
• 22:45
  SPEAKER_00: And I really encourage everybody.
• 22:46
  SPEAKER_00: But thank you so much, Dr.
• 22:47
  SPEAKER_00: Bowers and Larda.
• 22:48
  SPEAKER_00: It's been so wonderful to chat with you.
• 22:51
  SPEAKER_00: Absolutely.
• 22:52
  SPEAKER_02: Yeah, and it's a great product for men too.
• 22:54
  SPEAKER_02: I know we didn't quite get that in there, but I do have a lot of men that just will use the serum, and they're so bad about using things, but once you know, in three to four weeks, their skin is just so much healthier and thus younger looking.
• 23:08
  SPEAKER_02: So thank you so much for having us on here to discuss it.
• 23:13
  SPEAKER_02: We love the product, and it's fun to keep up with all the new changing dynamics in dermatology.
• 23:19
  SPEAKER_00: Absolutely.
• 23:20
  SPEAKER_00: I love that you brought up, you know, male-oriented skincare.
• 23:23
  SPEAKER_00: I think that's something we really need to push out there, you know, for all the men that for all the wives or the mothers or you know, anyone listening.
• 23:31
  SPEAKER_00: Yes, exactly.
• 23:32
  SPEAKER_00: If you need options, I mean that's very important.
• 23:36
  SPEAKER_01: I also just want to add in, you know, our hair follicle serum, which has all of the products are award-winning and have gotten, you know, very fast awards by everything, you know, from New Beauty Consumer to Fast Company, which puts Stefanash in the realm of business awards, etc., as the best innovative company, actually, by Fast Company in uh 2024, but hair follicle serum as well, defense and containing.
• 24:02
  SPEAKER_01: And you know, we're we're not chasing other ingredients in the industry and trying to do something with those.
• 24:08
  SPEAKER_01: We're always looking at something new to do with defense.
• 24:11
  SPEAKER_01: And so just as you said, you know, the nail serum, uh, very, you know, very effective product, uh works very fast.
• 24:19
  SPEAKER_01: And um stay tuned because we're always coming out with something new.
• 24:23
  SPEAKER_00: That that's really exciting.
• 24:24
  SPEAKER_00: No, I can't wait to see what the brand comes out with.
• 24:27
  SPEAKER_00: I'm I'm a huge fan, truly.
• 24:29
  SPEAKER_00: I mean, it's it's really innovative stuff.
• 24:30
  SPEAKER_00: And I I really encourage everybody, you know, anyone who tunes into our podcast, we're very science-oriented here.
• 24:36
  SPEAKER_00: So if you love the science of skin and you love finding things that actually work, this is the brand.
• 24:42
  SPEAKER_00: You guys gotta check it out.
• 24:43
  SPEAKER_00: And I will link everything in the show notes.
• 24:45
  SPEAKER_00: But if you guys have any questions at all, please chime in, send us an email, and let us know.
• 24:50
  SPEAKER_00: And we can definitely connect you to the Definage team if you have any further questions.
• 24:54
  SPEAKER_00: But thank you so much, Dr.
• 24:55
  SPEAKER_00: Bowers and Marta.
• 24:56
  SPEAKER_00: It's been truly an honor to host both of you.
• 24:59
  SPEAKER_00: Yes, thank you.
• 25:00
  SPEAKER_00: Thank you.
• 25:01
  SPEAKER_00: Hey guys, so I hope you love that episode.
• 25:04
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• 25:09
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• 25:52
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• 26:03
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• 26:08
  SPEAKER_00: Thank you.