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How Four Berlin Chemists Accidentally Invented Oral Progesterone
How Four Berlin Chemists Accidentally Invented Oral Progesterone
Danger and astonishment: a chemical miscalculation in Berlin in 1938 produced a drug swallowed by patients on six continents for more than six decades - but it was not the progesterone replacement doctors thought they had. How did a project to make oral testosterone become the world's first orally active progestogen, and what crucial limitation kept it from being the hormonal miracle it promised?
In this episode, we tell how four chemists at Schering AG synthesized ethisterone while pursuing an orally active testosterone and how…
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