Brain Metastases with HER2-Positive Breast Cancer — An Interview with Dr Sarah Sammons on Optimal Management Approaches

Research To Practice | Oncology Videos · Aug 26, 2025 · 45m

Featuring an interview with Dr Sarah Sammons, including the following topics:

Development of brain metastases in patients with HER2-positive and HER2-negative breast cancer (0:00)

Local therapy approaches for the treatment of brain metastases (8:23)

Treatment options for patients with HER2-positive breast cancer and CNS-only disease progression (16:36)

Clinical presentation of leptomeningeal disease; management of functional sequelae associated with brain metastases (19:07)

Investigational agents for the treatment of brain metastases in HER2-positive breast cancer (25:01)

Case: A 65-year-old…