Latest / King Dems Podcast | Growth Mindset, Leadership, AI and Business Insights / The Neuroscience of Empathy: Why Brains Need Friends w/ Dr. Ben Rein (Stanford Scientist)
Transcript
- 0:00I am going to ask you a question that was sent to you by my
- 0:03partner and she says this, She says from your perspective,
- 0:06what's the most exciting or surprising discovery about the
- 0:10brain in recent years? We think for a minute, Oh my
- 0:13gosh, there's so many. Let me give you 1 from my book
- 0:16that so. Welcome to the King Dems
- 0:24Podcast, where we share the stories of extraordinary people
- 0:27and dissect hot, relevant topics that shape our world.
- 0:31From visionary leaders to trailblazing creatives, we
- 0:33uncover the mindset, strategy, and grit behind greatness.
- 0:37Whether it's business, culture, or personal growth, we ask the
- 0:40real questions. This isn't just conversation,
- 0:43it's transformation. The Kingdom's podcast, Your next
- 0:46breakthrough starts here. Music licencing reimagined.
- 0:52Before we dive back into today's conversation, I want to share
- 0:54something important. This episode includes a pay
- 0:56partnership with Better Help, a platform designed to make
- 0:58starting therapy easier. I know from my own journey as a
- 1:00leader and entrepreneur that life can sometimes feel
- 1:01overwhelming. There are seasons, severe
- 1:03stress, uncertainty, and pressure build up, and you need
- 1:05a safe space to process it all that severe therapy comes in.
- 1:07Therapy isn't only for people facing clinical challenges.
- 1:09It's the space to reflect, grow, and find better ways to my
- 1:12stress, relationships and pessima goals.
- 1:14It takes the courage to seek help, but it's also one of the
- 1:16smartest investments you can make in your mental and
- 1:18emotional world. That's why I'm proud to
- 1:20highlight. Better help with better help.
- 1:21Think you feel out of a short question there and get match to
- 1:24the credential therapist in just a couple of days.
- 1:25If the first match doesn't feel like the right field, you can
- 1:28easily switch therapist at no actual cost until you find
- 1:30someone who should connect with you.
- 1:31Inside the platform, you also find tools like Donelline and
- 1:33group sessions on different topics that can support your
- 1:35growth. And with over 7000 reviews and
- 1:364.5 trustpathy, reason, Better Help is a platform you can rely
- 1:39on. So if you feel like you'd
- 1:40benefit from talking to a therapist, visit
- 1:41betterhelp.com/contained. That's betterhelp.com/contained
- 1:44to get 10% off your first mother therapy.
- 1:46Once again, this is a big partnership with Better Help and
- 1:48I encourage you to take that first step if you've been
- 1:50thinking about it. Sometimes the best you can make
- 1:52ease in. Yourself real life, ladies and
- 1:55gentlemen, you'll once again welcome to the Kingdom's
- 1:58podcast. And today I've got with me a V
- 2:02VIP14 out of New York, United States of America.
- 2:07Mick, welcome, Doctor Benjamin Ryan.
- 2:12How are you, Doctor Ben? I'm great man, Thanks for having
- 2:15me. It's good to be here.
- 2:17Wow, wow, finally, finally six months in the making.
- 2:21And of course, you know, we finally have you here.
- 2:24And before we hit the record button, I was saying it like it
- 2:28feels like this man is not just a genius.
- 2:31This man is also a seer. Probably he sees the future.
- 2:37I think we should have futurist to to your list of titles
- 2:41because you actually did like a perfect timing on the better
- 2:47help partnership. So better help reached out to me
- 2:51last week to become a brand partner with them.
- 2:57And you know, this is highly, highly connected to the work
- 3:01that you do to mental health. It's a therapy and it's it's a
- 3:06good time. It's a good time to be on the
- 3:08podcast and you actually timed it perfectly.
- 3:11So I appreciate you and of course, like I like to see in
- 3:16every of my episodes, gratitude is good attitude.
- 3:20When a person shares their time with you, they share their life
- 3:23with you because the SI unit for measuring life is time.
- 3:27So I will give you your flowers. Please sit back and let me read
- 3:31out your introduction. So ladies and gentlemen, to do I
- 3:35have the pleasure of speaking with Doctor Benjamin Brain, a
- 3:39neuroscientist, educator and award-winning science
- 3:42communicator. Doctor Ben is the Chief Science
- 3:46Officer of the Mind Science Foundation and adjunct
- 3:49instructor at Stanford University and founder of the
- 3:53Aspiring scientists Collision supporting students in over 75
- 3:58countries. He's groundbreaking research
- 4:01spans autism spectrum disorder, empathy and the neurobiology of
- 4:07social behaviour, and he has authored more than 20 peer
- 4:12reviewed papers. Beyond the laboratory.
- 4:15Doctor Ben reaches over 1,000,000 people worldwide with
- 4:19educational science videos on TikTok, Instagram and YouTube,
- 4:23where he breaks down complex neuroscience and tackles
- 4:26misinformation head on. His mission is to see is to make
- 4:30science accessible, accurate and inspiring.
- 4:34And today we're diving deep into his journey, research and
- 4:38impact. Once again, ladies and
- 4:40gentlemen, make welcome Doctor Ben Rain.
- 4:45Thank you for that intro by the way, because you know IA lot of
- 4:48the time people when I'm introduced, they'll just use the
- 4:50bio I have on my like website or whatever.
- 4:53But I could tell you, you really you customised that and I
- 4:56appreciate that. It means a lot really.
- 4:58Brother, we, we, we do our research here, you know, and of
- 5:00course, that is why we're climbing the global rankings.
- 5:04I'll tell you these. Well deserved.
- 5:06Thank you very much. I really appreciate it.
- 5:08You know, as at the time of recording, we are currently
- 5:12global top 2.5% and the goal is to make it to the global top 1%.
- 5:20I think you're going to do it. Absolutely with you on the show
- 5:23come on collaboration, teamwork makes the dream work.
- 5:27You know that's right. This dream is going to
- 5:30absolutely work we're going to smash it we are going to smash
- 5:33it. Let's.
- 5:34Do it. Wow.
- 5:36So let's go back to, you know, where it all started.
- 5:39You know your journey and your vision.
- 5:41What really you know initially treats you to neuroscience.
- 5:45And how did empathy and social behaviour become central to your
- 5:49research focus? Man, my relationship with
- 5:53neuroscience started way before I knew it started.
- 5:58It really began for me honestly in, in grade school, elementary
- 6:01school, I remember looking around my cafeteria, sitting at
- 6:06lunch and eating my sandwich or whatever and just noticing that
- 6:10there was the kids naturally distributed by like social
- 6:14behaviour. And, and you know, I, that's not
- 6:16how I thought about it when I was like 7 years old.
- 6:18But I noticed that there were really outgoing groups of
- 6:21children and then they were really shy, quiet groups, you
- 6:24know, and you see this everywhere now as an adult, you
- 6:26can look around a bar, a pub, you know, a library, a concert,
- 6:30whatever, you name it. You look around, you can see
- 6:32this distribution of how people treat and act towards others.
- 6:36And I thought that was really interesting when I was young
- 6:38because I was, I was like, why? Why are some people really
- 6:41outgoing and others are really shy?
- 6:43But I didn't think about it obviously from a neuroscience
- 6:45lens. But later on when I got to my,
- 6:48my college, I was studying psychology and I was interested
- 6:52in that. I was interested in social
- 6:54psychology, why people act the way they do and, you know, in
- 6:57social interactions. And I knew I had an interest in
- 6:59the brain. I knew I had some, like there
- 7:01was something inside of me that said the brain is the
- 7:04interesting part. It's not about the behaviour,
- 7:06it's about what's driving the behaviour, right.
- 7:08Like this organ, this mysterious organ up here in the dark.
- 7:10What's it doing? And but I was afraid of
- 7:13neuroscience. Honestly, I was.
- 7:14I was. Everybody thinks you have to be
- 7:16a genius to to be a neuroscientist.
- 7:18I don't know. And I.
- 7:20Didn't well, I didn't believe in myself And, and you know, the
- 7:23reality is if you want to become a neuroscientist or you want to
- 7:26become, you know, any sort of scientist or doctor, whatever,
- 7:28you have to take, you know, genetics, molecular biology,
- 7:30biochemistry, all these really challenging courses.
- 7:34And I didn't know if I had it in me.
- 7:35I was really intimidated by that.
- 7:37And so I stayed studying psychology for a while, kind of
- 7:41feeling like I was doing the wrong thing but not willing to
- 7:44confront it. And then in my second year of
- 7:48college, I had the most terrifying nightmare of my life.
- 7:51And I'll spare you the details of the nightmare, but the
- 7:53important part is that I woke up and I sat up in bed and I
- 7:56thought, Oh my goodness, how did my brain do that?
- 8:00How did my brain generate this whole environment, this world
- 8:04that I was interacting with and there were characters and I was
- 8:07making decisions and there was a storyline and people would say
- 8:09things to me and I would react. And not knowing that it was all
- 8:13happening within this one organ, the world I was inhabiting and
- 8:16the person I was, we're all within the same organ.
- 8:19And that just blew my mind. Like it something just happened
- 8:21where I was like, I need to understand the brain.
- 8:23It's not about behaviour, it's about this thing.
- 8:26And I literally changed that day.
- 8:27I went to my academic advisor, changed my major, changed my
- 8:31path, started studying neuroscience got as in those
- 8:35classes I was afraid of. So everybody, don't be afraid.
- 8:38Don't let your intimidations steer you in the wrong
- 8:40direction. Take it on.
- 8:41You were saying this before we started recording.
- 8:43I mean, if you really, if you want something, if you really
- 8:45believe in something you're capable of anything you can get
- 8:47right through it. And so now coming full circle,
- 8:50I'm able to, I've been studying for the last decade, the
- 8:52neuroscience of social behaviour and studying things like you
- 8:54mentioned, autism spectrum disorder, empathy, looking at
- 8:57the, the brain systems that drive these social changes and
- 9:01social differences in people and really getting it to the heart
- 9:04of that question I cared about as a child.
- 9:06And I'm, I'm living the dream. I'm enjoying all the, the work
- 9:09I'm leading. It's a lot of fun.
- 9:11Wow, you know, it's, it's quite interesting and I appreciate
- 9:16your what I say, authenticity and ability to the vulnerable.
- 9:24A lot of successful people want to paint a perfect picture, but
- 9:29I always tell people, people don't relate to perfection.
- 9:33People relate to excellence. And successful people are people
- 9:38who have failed multiple times. But you know, we're Brazilian
- 9:43enough to find ways to be successful at the things that
- 9:47they do. Imposo syndrome.
- 9:50A lot of people struggle with imposo syndrome, but I'm quite
- 9:54grateful. I'm a man of faith, by the way,
- 9:56I'm a Christian and at the early age of 16, I went to Bible
- 10:02school, graduated and you know, the faith was, you know, very,
- 10:07very ingrained in my heart. And do you want to know what my
- 10:11favourite Bible verse is? Philippians chapter 4, verse 13.
- 10:17I can do all things true crisis strengthens me.
- 10:19That's verse what I say sort of helped me in my life to beat the
- 10:26whole imposter syndrome thing. I'm not afraid to feel because I
- 10:30failed multiple times out of very early age.
- 10:33I was very poor at mathematics and failed twice at what you
- 10:39call the O level in Nigeria and third time asking, third time as
- 10:45a champ. I got it.
- 10:47So I feel like that experience made me have a very, very early
- 10:52encounter with failure. And we've been there, done that.
- 10:56But what would you say about like young people who try to
- 11:00chase perfection and I'm not able to get it.
- 11:03And because they probably feel like certain things, they feel
- 11:09like they're not worthy or they don't have a place in society.
- 11:15And going into the adulthood impulsive syndrome, you know,
- 11:20kicks in. I'd like for you to touch on
- 11:22that. Yeah, You know, I told you the
- 11:24very short version of my story, which basically sounded like I
- 11:28became a neuroscientist and it was successful, right?
- 11:30I left out a lot of details. And the reality is it wasn't, it
- 11:34wasn't just I changed my major and I poof, I was a Stanford
- 11:37neuroscientist. No, the truth is I've had I had
- 11:40setbacks like that all the way through my life.
- 11:42And when I was first applying to college, I thought I was, I
- 11:46thought I was smart and I thought I was gonna have no
- 11:48problem getting into colleges. And I thought I'll, I'll know
- 11:51I'm smart, you know, And so I applied to, I don't know, 12
- 11:54dozen schools. And the only school that I got
- 11:57into was my very lowest fall back, a school with like an 80%
- 12:00acceptance rate. And it's a, it's a, it's a
- 12:04great, it was a good school. I had a great education.
- 12:06It's West Virginia University. It's in West Virginia in
- 12:08America. And it's most known for being
- 12:11the number one party school in America.
- 12:12And I had a good time. I did, but I was disappointed
- 12:16with myself. I was disappointed with life.
- 12:17And that was the first time where I felt like, Oh my gosh,
- 12:21my life is not going to be what I thought it was going to be.
- 12:23You know, like I like I've, I had this ambitious vision and
- 12:27now I just took this scary detour into I don't know what my
- 12:31life is going to be like. And that scared me that kind of,
- 12:34you know, it's intense to say this, but it kind of traumatised
- 12:37me where that was the first time I felt like my well-being, my,
- 12:40the sustainability of my career was threatened.
- 12:42So I went to my, my undergrad, I did it.
- 12:45I worked as hard as I could. I had a four point OGPAI
- 12:47graduated in, in three years. I, so a year early, I worked in
- 12:51all these research labs. I did everything I could so that
- 12:53when I was applying to my PhD, it wouldn't happen again, that I
- 12:56wouldn't get disappointed like that.
- 12:58And so I applied to all these great schools now like 10, once
- 13:02again, I only got into my lowest fall back, which is the school
- 13:05that I did not want to go to. And I was like, Oh my goodness.
- 13:08Again. I worked so hard, like I was
- 13:11100% more deserving this time around.
- 13:14I had such a higher GPAI had all this extracurriculars, like I've
- 13:17poured everything into being successful academically and I
- 13:20still didn't get what I wanted. And that broke my heart.
- 13:23And so, but I kept my head up and I stayed optimistic.
- 13:26And so I went to my PhD and once again, I worked my ass off.
- 13:30Sorry, I don't know if we swear on this podcast, but.
- 13:33Feel free. Feel free brother.
- 13:35All right, I'll, I'll try and take it easy here.
- 13:37Not, not like a off the rails cursor or anything, but I worked
- 13:41really hard and I ended up publishing, you know, a bunch of
- 13:44papers and having a really high GPA and getting all these
- 13:47awards. And I went to the next step
- 13:49where you're after a PhD, you apply to a postdoc.
- 13:52If you're doing a, if you want to be a researcher, it's kind of
- 13:54like a residency. When doctors do a residency, a
- 13:56postdoc is like the scientist equivalent.
- 13:58And so I applied to Stanford, MIT, Johns Hopkins, Yale,
- 14:03Harvard, all these great schools.
- 14:05And I thought, please do not let me get disappointed again.
- 14:08And I got offers from Stanford, MIT, Yale, Duke, Johns Hopkins,
- 14:13I could have gone to any of those places and I end up going
- 14:15to Stanford. And that was I Stanford.
- 14:20I went to Stanford because it's one of the top institutions in,
- 14:23in the US And when I visited, so I'm from the East Coast and the
- 14:25East Coast is very where, where I'm from at least, is very grey
- 14:29and cloudy and you don't get a lot of sun.
- 14:30It's cold, we get a lot of snow. And then we, my wife and I, we
- 14:33visited Stanford and we were like, yeah, like this is, it's
- 14:36like blue skies, sunny, gorgeous.
- 14:38And it was, it was kind of the, the environment that that sold
- 14:41us and also the, the lab that I was going to work with.
- 14:43That's amazing. But I, but I share all this to
- 14:45say, like, you can be disappointed and humiliated and
- 14:51just terrified over and over, and then you can have a
- 14:55breakthrough. And I think that it's, it's
- 14:58important to not bang your head against a wall that's going
- 15:01nowhere. But I think, you know, you want
- 15:04to make calculated decisions about this stuff, right?
- 15:07Like, I don't think that in any universe, even if I, let's say
- 15:10the story ended in a bad way, where once again, I didn't get
- 15:12into all those places, I don't think I would look back and say,
- 15:15man, I regret trying so hard. You know, and I regret having
- 15:18all that success academically, But I, it did pay off because I
- 15:21was resilient and I kept pushing through.
- 15:24And, you know, I, I think that as long as we know that the
- 15:29challenge we're up against is worthwhile and that the
- 15:32outcomes, the potential upside is there and it's what we want,
- 15:36You know, it's, it's just like the same thing with taking those
- 15:38classes. You know, you might be afraid
- 15:39of, of something and then you do it and just 'cause you have to
- 15:41do what you get through it. You know, I think if you love
- 15:43something and you want it and you keep fighting for it,
- 15:47there's going to be something good.
- 15:48It may not be the, you know, I can't promise, you know, you're
- 15:50going to get everything you want, but you will breakthrough
- 15:52eventually. And and you can imagine what it
- 15:57has been like for me. I mean, imagine, imagine going
- 15:59through that and going all these universities saying you're not
- 16:02worth our time, you're not worth, you can't be a student
- 16:05here. And then finally, after 10 years
- 16:07of working on that or seven years of working on that, you
- 16:09get to Stanford and you're in front of all these scientists
- 16:12who are Stanford scientists and they all come from Harvard and
- 16:14UC Berkeley and all these great schools.
- 16:16And you're like, I've never been in anyone like around these
- 16:19calibre people ever. Imagine the imposter syndrome,
- 16:22right? That was difficult, but it was
- 16:26fine. I was completely fine.
- 16:28I kept up with everyone, you know, I, I, it was completely
- 16:31fine. There was no issue.
- 16:32And, and I could have been alongside these people all
- 16:34along. I think that the truth is, you
- 16:38know, another major lesson I like to tell people is this all
- 16:41started because I didn't apply myself in high school.
- 16:43I didn't have the grades that I, that I thought I had in high
- 16:46school. I, you know, I was capable of
- 16:48getting high grades, but I wasn't really trying in my
- 16:50classes. And if I had tried harder, then
- 16:53I would have probably gotten into a better college and then I
- 16:55would have gotten into a better PhD and I wouldn't have been
- 16:57fighting all that time. And so, you know, I think for
- 17:00young people, it's important to take academics seriously because
- 17:03academics in many cases will be the key to unlocking whatever
- 17:07the future is. And when that when you reach
- 17:09that point, if you reach that point like me, where you open
- 17:13that door, you know, use that key and you twist that knob and
- 17:15you open that door and it's a horrifying reality on the other
- 17:18side and it's not what you expected.
- 17:20That's a real wake up call. And so if you can apply yourself
- 17:23earlier and really start taking stuff seriously before it
- 17:26becomes too late, you're gonna thank yourself for doing that.
- 17:30And I wish I had done that myself.
- 17:32Wow. I think this is a very, very
- 17:35great a Big Brother advice. You know, here in the UK, it's
- 17:39really, really puzzling to me how the key to here, the Gen Z
- 17:46generally do not really value education, especially tertiary
- 17:50education. And then they tell me, oh, if
- 17:53you went to university, I'm not interested in going to
- 17:55university. I'm like, OK, there's one in my
- 17:59apartment. I had to talk to you.
- 18:02I said, you know what, if you become well educated, you may
- 18:08never become very rich or you will never become very poor and
- 18:15good. Point unless you take out too
- 18:19many student loans. You know, back to your point of,
- 18:22of, of, you know, at least trying, you know, Nelson Mandela
- 18:26of blessed memory, he said something.
- 18:28He said if we try, we may fail. Or if we don't, we have failed,
- 18:34at least try. And I love your theme of
- 18:37resilience. It's something that I preach,
- 18:41you know, on this podcast, you know, all the time.
- 18:44Resilience is, is very important.
- 18:46You know, keep going and never let anybody stop you.
- 18:50Never let anybody put you down. Never let anybody, you know, try
- 18:55to put you in a box because we all don't know what we are
- 18:58doing. And, you know, some people try
- 19:00to advise other people based on their own worldview or based on
- 19:06the limitations that, you know, they have on their minds or the
- 19:10cast on themselves, right? And they try to project it and
- 19:13other people. And that's something I very,
- 19:16very, very much detest. I remember when I was, you know,
- 19:19about to start this podcast, I'll see someone who was very
- 19:24opposed to it. And I think that was the reason
- 19:27why that relationship had to end.
- 19:30It's crazy. You can't stop me from my
- 19:32dreams. You can't stop me from my goals.
- 19:33And I was very, very upset about it.
- 19:37And they were like, oh, you're finance guy, What are you?
- 19:40Why are you going into the media?
- 19:43Do you need permissions from anybody?
- 19:45If you're passionate about something and go for it.
- 19:48If you have a dream, always go for it.
- 19:50And of course, keep. And, you know, can I add
- 19:52something on that because we were talking earlier before we
- 19:55started, before we turn on the recording, we were talking
- 19:57about, you know, your journey and what you're up to nowadays.
- 20:00And you know, I was noticing because you're talking about
- 20:03this theme of. Basically, I was realising that
- 20:07your values and beliefs and your interests are all perfectly
- 20:11blended into the theme of this podcast.
- 20:13You know, like you've taken all these different things that you
- 20:16come that you care about, right? Like whatever finance, business,
- 20:20psychology, growth mindset, you've taken all these, all
- 20:22these angles that have influenced you in your life and
- 20:25you compiled them into one podcast.
- 20:27Then I think another tip for young people and anybody really
- 20:30is like, you know, you will naturally gravitate towards what
- 20:34you care about. And it's for me, like I, I
- 20:38started this is getting really complicated now, but when I
- 20:42started my PHDI was just happy to be there because I had gotten
- 20:46almost rejected from all PhDs and I just wanted to be
- 20:49successful. That's all I wanted.
- 20:51I wasn't thinking about, oh, I want to study social behaviour
- 20:53anymore. It didn't matter.
- 20:54It was just like, I need to just be successful.
- 20:57That's I need to, I need to regain the lost ground that
- 21:00I've, that I've lost, right. And so I ended up joining this
- 21:02research lab and started working there for in about a year in it
- 21:07occurred to me that I was studying autism spectrum
- 21:10disorder, that I had joined the lab because they were a
- 21:13productive lab. And I thought, this isn't the
- 21:14lab that's going to give me the best shot at being having a good
- 21:16career. But I found myself, I had carved
- 21:20out this little niche of studying social behaviour
- 21:23without even thinking about it. It was just like my gut and my
- 21:26subconscious mind had sort of geared me into this direction of
- 21:29doing what I love. And I think, you know, I got
- 21:31this fortune cookie years ago that I always think of that
- 21:34says, look for the dream that keeps coming back.
- 21:37It is your destiny. And that's kind of what I think
- 21:40about with your podcast and with my journey and, and with just
- 21:43with your journey and like this person telling you like, oh, why
- 21:46you're a finance guy? Why are you talking about this
- 21:48stuff? Like, or why are you going into
- 21:50media like that's that's you. That's that's what makes you who
- 21:53you are. That's what makes you unique
- 21:55and, and what you care about. That's what your brain is
- 21:57interested in. And you're naturally suited to
- 22:00put out good materials on this because people, people like what
- 22:03they're good at. People are, they're naturally
- 22:06driven to the people, the things that they excel at.
- 22:07And so if you are good at something and you're have
- 22:11interesting ideas about it, your podcast is going to do well and
- 22:14look at where you are. So I think, you know, follow
- 22:17that dream to the listeners, you know, like, listen to your gun
- 22:20and listen to your heart because it's it's telling you your
- 22:24destiny. Maybe if my fortune cookie was
- 22:25right. Well, I love and respect to you,
- 22:29you know, absolutely love how you you framed it so, so
- 22:34beautifully. It's interesting.
- 22:38You're welcome. I tell people this, right?
- 22:40There's potential and there's credentials.
- 22:43When you're younger, you you judge based on your potentials.
- 22:46But as you grow older, you get judged based on your
- 22:49credentials. But you don't want to be a
- 22:52person who has, you know, massive potentials but little
- 22:57credentials. And a lot of people suffer from
- 22:59this bandwagon effect, you know, wanting to do what other people
- 23:03are doing. You are not other people.
- 23:04You're yourself. And I think a lot of people get
- 23:07discouraged by the opinions of other people.
- 23:11It's crazy. Think about it like if I had
- 23:14listened to that person at that time saying do not do
- 23:20podcasting, I wouldn't be here speaking with, you know, one of
- 23:25the greatest scholars of my generation, you know, today.
- 23:31Think about. It I'm honour for you to say
- 23:32that. Thank you.
- 23:34To walk and I think about my body of work.
- 23:36I've spoken to, you know, people that are highly successful from,
- 23:42you know, different parts of the world in your neck of the woods.
- 23:45I spoke on people who weren't in school and have it, you know,
- 23:48for it. It's really mind blowing.
- 23:50People who are #1 in the world, you know, at whatever ease that
- 23:55they're doing. And if I listen to, you know,
- 23:58that person saying do not do this, what would happen?
- 24:01So I don't know, like what what would you say to the people out
- 24:04there in terms of, you know, sticking to their guns and
- 24:10believing in themselves? And if you're able to maybe
- 24:15butchers that with a personal story of yours in a situation
- 24:18where you wanted to go for something or somebody said
- 24:22otherwise apart, you talk to your gods, your instinct and you
- 24:26know, went for it and he was successful.
- 24:30Yeah, for I, you're bringing up something immediately, you know,
- 24:34so I've always been really ambitious, which is probably
- 24:37clear from my story. And, you know, the career path I
- 24:39chose, you know, and, and I like to reach for things.
- 24:42I like to set goals and, and get after them.
- 24:44And just for everybody listening and yourself included, you know,
- 24:47I, I wanted to make it very clear.
- 24:50I was completely full of anxiety all the way along that journey I
- 24:54just described. Imagine how it felt when I
- 24:56didn't get into that school that I wanted to and I realised, Oh
- 24:59my gosh, like I was horrified for my future.
- 25:02And I was and I was motivated to keep on reaching and keep on
- 25:05reaching. And so I don't want everyone to
- 25:07think, you know, oh, this guy is just full of confidence and he
- 25:10believes in himself all the way. No, you can.
- 25:12It's, it's going to be normal for you to experience that for
- 25:14sure. But an example of what you're
- 25:16talking about when I was working at Stanford, this is very
- 25:20personal, but I don't mind sharing personal things.
- 25:22When I was working at Stanford, I was seeing this therapist
- 25:24because I was, and I was talking to her about exactly what we've
- 25:29been talking about here, that I'm, I want so badly to just
- 25:32succeed in my career and I'm so afraid of setbacks.
- 25:35And I've always been like, I want to be the best at this, you
- 25:38know, I want to be like the number one scientist, whatever.
- 25:41You know, I've always just been ambitious like that.
- 25:43And this, this therapist, she told me basically, it's OK to be
- 25:49average. She was like, if you, you know,
- 25:51I, I bought this book something, something about basically it's
- 25:55OK to be average. And I gave it to my son and he's
- 25:57reading it because I want people to understand it's OK to be
- 25:59average. And I was like, that's really
- 26:02comforting advice, but that's not what I want.
- 26:06That's I had to listen to my heart, which was telling me,
- 26:11yeah, you're reaching for something so far away and it's
- 26:15stressful because you want it so bad and you don't know what
- 26:17you're going to, if you're going to get it or not.
- 26:19And so sure, it would be so much easier to say, you know what,
- 26:22I'm OK with not getting it. I'm OK with being average.
- 26:25But that's not the journey that I wanted for myself.
- 26:27That's not what I how I view my life and how I view myself, you
- 26:30know, I want to reach. And if I fail, I fail, but I
- 26:32don't think I'm going to fail. And that's a big part of it, by
- 26:34the way, is just being optimistic and having that
- 26:36growth mindset. And I remember just, you know,
- 26:41this was right when I joined Stanford and I was dealing with
- 26:43that imposter syndrome that I described.
- 26:45And I remember like three years after that, I was in, I don't
- 26:50know, Iceland or Italy. I've been to Portugal.
- 26:52I've been flown out to give talks.
- 26:55And I thought, Can you imagine if I had, if I had just decided,
- 26:58yeah, I want to be average. Like, I wouldn't have achieved
- 27:01this for myself. I wouldn't have experienced
- 27:03this. The satisfaction of attaining
- 27:05that goal that I wanted so bad. And that's what drives me.
- 27:07Is this the satisfaction of setting a goal and then working
- 27:12my way to it? I love the feeling of progress.
- 27:15And I, I don't think I would be happy if I, if I just said, you
- 27:18know what, I'm going to stop reaching.
- 27:19It's, it's not what's meant for me.
- 27:21And so my advice to anybody is to basically like set goals and
- 27:28figure out what you want, right? If by setting a goal, you can
- 27:31learn a lot about your preferences and what you want
- 27:34from life, you know, because if you're setting a goal and it's
- 27:36like, all right, I'm a scientist.
- 27:37My goal is to win a Nobel Prize. You know, it's like, OK, that's
- 27:40a lofty goal. Like, I don't know, 0.0001% of
- 27:44scientists win the Nobel Prize. I'm making that up.
- 27:46But it's really, really, really small.
- 27:48That was my goal when I was young, by the way.
- 27:49I'm now smart enough to realise, or I guess wise enough to
- 27:52realise that that's never gonna happen.
- 27:53I'm never gonna win a Nobel Prize.
- 27:54I'm OK with it. But if your, if your goal is
- 27:57like, I wanna win a Nobel Prize, OK, good.
- 28:00Like hunt after that, right? Make that your journey.
- 28:03Make that your, your meaning of life, right?
- 28:07But if your goal is like I, I just want to like, take, have,
- 28:11make enough money to take care of my parents.
- 28:12It's like, OK, there's a lot of routes that you can take to that
- 28:14goal, right? Like you don't have to be as
- 28:16hungry as devoted, but identify sort of your ambition levels
- 28:20and, and what your dreams are. Because to me, that is one of
- 28:26the sort of meanings of life. I think like if anyone ever
- 28:28asked me, what do you think the meaning of life is?
- 28:30For me, it's about telling yourself this is what I want and
- 28:34going and getting it, carving that journey for yourself,
- 28:38right? I think of it like a, like a
- 28:39board game, right? It's like you get to pick your,
- 28:42your player and where they go and which direction you're
- 28:44headed or what kind of player you want to be like.
- 28:46That's life. You get to live 100 years and
- 28:49take whatever journey you want. And I think it's, I get sad when
- 28:52I think about people who kind of just float in that journey and
- 28:56they don't steer their own journey.
- 28:57And I think it's important, especially as young as you can
- 29:01be, the younger, the better to start thinking about where is
- 29:05that dream and how do I get there?
- 29:07Because for me, that's the most satisfying thing in the world.
- 29:10And that dream can change, by the way.
- 29:11So don't worry, mine has changed.
- 29:15That's called P13. You know, along the journey of
- 29:18life, I remember a particular lecturer, you know, when who
- 29:23taught me in my professional accounting classes on strategy.
- 29:28He said, you know, that different types of strategy and
- 29:31you know, strategy comes with planning.
- 29:33And some people have, you know, that's plan to be average.
- 29:38And you know, they say something, if you don't plan,
- 29:43you plan to fail. So not having a plan is a plan
- 29:46on its own. It's just a plan to fail.
- 29:49But you know, back to your point on, you know, it's OK to be
- 29:53average. I don't like that idea at all.
- 29:55And you know, I'm grateful I was able to read a book, alien life,
- 30:00It's called Conquering an Enemy called Average by John Mason.
- 30:04I think I'll try to put the link to that book in the description.
- 30:08And of course, you should, you should give, give that book to
- 30:11your son as well because for me, no, no, average is a no, no.
- 30:16Like I'm not born to be average in Nigeria.
- 30:21If you are to join the military and as a graduate from
- 30:25university, I thought about joining the military and about
- 30:29somebody told me that if you join the military as a graduate
- 30:32from university, you did not go to the combat school.
- 30:36You can never become a general. And immediately that dream just
- 30:41died. Like I will never join an
- 30:44organisation where I can never rise to the top.
- 30:48No, no, no, no way, No way. And that has actually like,
- 30:52pushed me in terms of the way my career has progressed.
- 30:56And when you join the big four accounting firms, they always
- 30:58tell you, you know, join us and associate.
- 31:00You can actually work your way up to become a director or
- 31:03partner, you know, having share of profit.
- 31:06Yeah, that's cool. That's interesting.
- 31:09You must always have that pathway, reasonable pathway to
- 31:13the top. And of course, you know, if you
- 31:15work, if you put in the work, right, you should get, you know,
- 31:18certain expected results. That's what I like personally,
- 31:22but I stand to be corrected. But when when we come back to
- 31:25science, you know, the autism and of course our
- 31:28neurodevelopment are disorder disorders, right?
- 31:31Your PhD identified neural systems are regulating social
- 31:36behaviour in autism. So looking at that field now,
- 31:40which therapeutic pathways seem, you know, most promising?
- 31:45But you have gene therapies, epigenetic approaches or the
- 31:49pharmacological tools like MDMA. So which pathways actually would
- 31:57I say are effective or efficient in your opinion?
- 32:02Yeah. So when it comes to autism
- 32:04spectrum disorder, which is characterised by difficulties in
- 32:09social interactions, there's nothing on the market right now.
- 32:13If if you or a loved one is someone who is on the autism
- 32:18spectrum and you suffer with social interactions and you want
- 32:21to enhance your interactions or feel more comfortable in
- 32:23interactions, there's no options.
- 32:25There's nothing out there. And, and before I even go any
- 32:27further in this topic, I just want to mention that there are a
- 32:33lot of people who are, you know, in the autism community or
- 32:36they're on the spectrum, they have loved ones with autism and
- 32:39they're, the idea of the treatment is, it's just, it's a,
- 32:44it's a terrible idea. It's basically that to treat
- 32:48this is to label it as a dysfunction and to say that
- 32:52there's something wrong with me. But this is what makes me
- 32:55unique. And so I, I just want to qualify
- 32:58that by just acknowledging that it is not my belief that
- 33:02everyone on the autism spectrum should have some treatment.
- 33:04That's not at all what I believe.
- 33:05In my PhD, though, I got to studying the biological basis of
- 33:09autism and discovered, you know, there are no treatment options
- 33:11for those who are struggle with their symptoms and want
- 33:14treatment. And that was sort of the focus
- 33:16of the lab. And so I got into studying like,
- 33:18what are these brain systems and how could they potentially be
- 33:20altered, which is interesting, altered to enhance sociability,
- 33:23I should say, which is interesting because it got
- 33:26exactly at the question that I was looking at when I was young,
- 33:28which is like, how do you know if, if you could go into the,
- 33:31the table where the quiet kids are sitting and tickle a certain
- 33:34brain system and make them feel like sitting with the, you know,
- 33:38outgoing kids? Like, wouldn't that be
- 33:39interesting? What, what brain systems are
- 33:41there that, that do that? Right?
- 33:42It's such a fascinating question to me.
- 33:44And so it turns out it's, it's very complicated and very
- 33:47molecular, basically. But I will say this, the root
- 33:53cause of autism in most cases or many cases I should say, I guess
- 33:57is genetic. And so it is possible that if
- 34:03done early enough, if like, because what happens is if you
- 34:05have a genetic mutation, so the gene is coded as it is.
- 34:10And then if there's a change in one of the base pairs, let's
- 34:12say, and it, each gene corresponds with a physical
- 34:16protein. So you have, you know, 30,000
- 34:18genes, 30,000 proteins floating around your cells or that, you
- 34:22know, you could have up to 30,000 floating around your
- 34:24cells. And so I like to think of it as
- 34:26like a house. Let's use that analogy.
- 34:29So your cell, each of your brain cells is a house.
- 34:32And like, you know, this book is 1 protein, right?
- 34:36Like this book serves a purpose. Like this water bottle is a
- 34:39protein. It serves a purpose.
- 34:40And so there's a blueprint to build this water bottle.
- 34:43There's a blueprint to print this book.
- 34:45Those are the genes, right? So the genes are the blueprint
- 34:48and they build the actual like physical structures.
- 34:51And So what could happen is you can have a mutation in one of
- 34:54the genes which causes the blueprint to basically change.
- 34:58So let's say there's a mutation in the gene for this water
- 35:01bottle and it comes out and there's a hole in the bottom,
- 35:04and now it's no longer functioning as a water bottle
- 35:05because the water is draining out the bottom.
- 35:07That's sort of like what happens in cells where if you have a
- 35:09genetic mutation, the protein in your cell that's supposed to do
- 35:13something is not doing what it's supposed to do.
- 35:16It's it's functioning improperly.
- 35:18And that can change how brain cells are functioning in a way
- 35:21where if that change happens to be going on in a brain area
- 35:25involved in social interaction and the brain starts that brain
- 35:28area starts functioning differently, it can result in
- 35:30changes in social behaviour. And so if this genetic change is
- 35:35caught early enough, super, super, super early, like in the
- 35:38womb in it before, you know, the brain has developed, could
- 35:43theoretically reverse autism spectrum disorder before it even
- 35:48like begins. Very controversial idea though,
- 35:50of course, right. It's like if we're gonna do gene
- 35:53therapy, if anyone's gonna do gene therapy, you know, the, the
- 35:56first use case should be anything that's fatal, right?
- 35:58If there's someone, if you're gonna suffer from some condition
- 36:00like like Huntington or something like that,
- 36:03Huntington's disease and you're gonna be struggling your whole
- 36:05life with with condition, you know, this, whatever it may be,
- 36:10and you're gonna die young. Those are the things that should
- 36:12be used for gene therapy, autism even even to propose that is
- 36:15super controversial to use gene therapy.
- 36:17But hypothetically, you know, it would kind of make sense because
- 36:21it's a genetic disorder in many cases.
- 36:23Now, the other thing you mentioned, it's like
- 36:24pharmacology, right? So you can use pharmacological
- 36:28agents, drugs, in other words, to target epigenetics, which is
- 36:33kind of sounds confusing because epigenetics is how experience
- 36:38changes our, our gene expression.
- 36:41So expression being not the code or the blueprint, but how many
- 36:44of these water bottles do I have?
- 36:46You know, And so you could think if I'm really thirsty, I might
- 36:49want to have ten of these water bottles around.
- 36:51And so I'll go to the store and get 10 of these bottles or I'll
- 36:53make 10 of them from the blueprint.
- 36:55That's how cells act, right? Like you have an experience,
- 36:57like my experience as being thirsty, I need more of these
- 36:59cells are the same. Something changes in the cell or
- 37:01we need more of that or we need less of that.
- 37:03Let's change how many copies of that gene we're producing.
- 37:07That's epigenetics. And so while it would seem that
- 37:10only experience can do that, you can actually there are
- 37:14epigenetic drugs that you can basically go in and manipulate
- 37:19the parts of the cell that make that change happen or manipulate
- 37:24the accessibility of the DNA. And there is some evidence from
- 37:28the lab that I was do working in and some of my own research that
- 37:31doing that and altering the gene expression through a drug can
- 37:35change social behaviour as well. And so that's, you know, a
- 37:40possibility. But again, none of these things
- 37:41are actually like demonstrated, right?
- 37:43Like we haven't done this in human beings.
- 37:45We don't know if this is useful. And then the last one though, is
- 37:47MDMA. And I've also studied MDMA, but
- 37:50in a different context. And for those who don't know,
- 37:51MDMA is ecstasy, the illegal drug.
- 37:55But I in my postdoc working at Stanford, I was studying how
- 37:59MDMA enhances empathy. And if you're curious, if you're
- 38:03neuroscientifically minded, it comes down to serotonin release
- 38:07in the nucleus accumbens, a certain brain area That's kind
- 38:11of irrelevant unless you want to get into that.
- 38:12But, but what's interesting though, is that we actually, we
- 38:15found that in in mice with those same genetic mutations that are
- 38:20linked to autism in humans, those mice socialise less.
- 38:24They also show reduced empathy. We can test empathy in mice
- 38:27also. Happy to get into that if you
- 38:28want, but they show reduction in social and empathic behaviours.
- 38:33And when we gave the mice MDMA, they became more social, they
- 38:37became more empathic. And I mentioned that MDMA's
- 38:42effects seem to be related to this serotonin release in the
- 38:44nucleus accumbens. Well, when we just know MDMA, we
- 38:48just stimulated serotonin in the nucleus accumbens.
- 38:51It had the same effect on the mice.
- 38:52So it's possible that that also could be an approach.
- 38:57You know, I actually personally, I see that less as a like a
- 39:00therapeutic for autism. I see that more of a just
- 39:04empathogen, which is what you know, and empathogen is a drug
- 39:08that's that enhances empathy. But I see that if we can target
- 39:11that system, it could be a useful tool for all of humanity.
- 39:15You know, I think that we are, we are living in a sort of
- 39:18unusual time right now. I would argue that the current
- 39:23era of humanity, at least in America, I'm not sure how it is
- 39:26over in the UK, but in America it feels like we're really kind
- 39:29of living through an era of low empathy.
- 39:31And I think part of that is because we interact.
- 39:34Yeah, I think part of that is because we interact online a
- 39:37lot. I think part of that is because
- 39:38we're super politically polarised.
- 39:40And so, you know, we can get into this, but the brain's
- 39:43empathy systems are very sensitive to how we view
- 39:46someone, whether they're on our team or not, basically.
- 39:48And that can be anything. It could be their political
- 39:50affiliation, it could be their religion, their race, their
- 39:54sexuality. If we see them as different from
- 39:57us, The brain scenarios that Dr Empathy literally just like
- 40:02don't come online as much. They show less activity.
- 40:05That's significant. And I think, you know, in a
- 40:07world that's very politically polarised where you look at
- 40:10anybody, at least this is how it is in America.
- 40:12You look at someone, you look at their clothes, you know, maybe
- 40:14they have a Red Hat on or maybe they have, you know, a blue
- 40:17shirt on or whatever it is. And you're like, oh, that
- 40:20person's on the other side. Empathy systems.
- 40:23Disengage and you basically view that person or your brain treats
- 40:28that person as less of a person and that's really problematic.
- 40:31And so, you know, do I really think that we'll be given people
- 40:36will be taking a drug to simulate their empathy?
- 40:39No, I mean, because how would that even work?
- 40:42And it's another ethical concern.
- 40:44But but hey, maybe, you know, maybe not in a clinical context
- 40:49where it's like like going to this, you know, clinic and take
- 40:53this drug and you're gonna feel empathy.
- 40:55But wouldn't it be cool if there was like, like instead of going
- 40:58to the bar and drinking alcohol, we went to a bar and drank in a
- 41:02pathogen, right? Something that stimulated
- 41:03serotonin release in the nucleus accumbens, made us all feel a
- 41:06bit more connected and more empathic and you know, not to be
- 41:10kumbaya, but like brought people together and actually drove
- 41:15connection and community. I think that that'll be
- 41:18interesting. And the reality is we don't know
- 41:21how to do that neurobiologically.
- 41:23But with the research that I did at Stanford, we know a little
- 41:25bit more about how we might do that.
- 41:27And I don't want to, by the way, before I go any further, I don't
- 41:29want to say I just said how we might do that.
- 41:32I know there's a lot of people out there with opinions on
- 41:33science. I don't want people to think
- 41:35that there's like some secret scientific society controlling
- 41:38what you drink at the bar. There's not.
- 41:39Scientists have very little control over the real world.
- 41:42We could control what happens in our labs.
- 41:43But even when it comes to policy, public policy, you know,
- 41:46we're very detached, unfortunately, because I think
- 41:49scientists often have a lot of good ideas.
- 41:51But yeah, I mean, you know, our our goal is to discover new
- 41:55things so that humanity, whether that's, you know, commercial
- 41:58entities like what if really, what if a drink came out, a
- 42:01brand came out that was like, you drink this and you're going
- 42:03to feel more empathy. It's, you know, there's no
- 42:05hangover. You can go to the bar and drink
- 42:06it. People be interested in that,
- 42:08right? It's kind of interesting idea.
- 42:10Or if there was a clinical drug that people could take and
- 42:12enhance their empathy, you know, or if what I always like to joke
- 42:16about is half kidding. Wouldn't it be amazing if right
- 42:19before a political debate, the presidential debates, all of the
- 42:22candidates had to take a drug that made them more empathic and
- 42:25made them see the other person's side a bit more?
- 42:28And so instead of going up there and just hurling insults at each
- 42:30other, they actually understood each other and had a real
- 42:33conversation about why they disagree.
- 42:35And not in a way that was hostile and violent and maybe
- 42:38not violent, but hostile and aggressive and sets this bad
- 42:41example for all of Americans to think That's how I treat the
- 42:44people on the other side. So anyways, as you can probably
- 42:47tell, you know, I care about community and connection.
- 42:52And, you know, this is also the whole, the topic of my my whole
- 42:55book, which I held up earlier as an example.
- 42:57But why brains need friends? I, you know, we need each other.
- 43:01And I think that the more we can understand the importance of
- 43:04that, truly, the healthier we will be.
- 43:07The research suggests that we will be healthier and we will be
- 43:09happier as well. Wow, I'll tell you something.
- 43:14Let's say like minds always find a way to connect.
- 43:19There's something I always see on the podcast and it's links
- 43:23back to the title of your book. It is hate when you can't
- 43:28collaborate. Why hate?
- 43:30You know, it's crazy how people always find something to act as
- 43:36a differentiator. We are all human, we all bleed
- 43:40red. And it takes a high level of
- 43:46when I say certain ease, right, I tell people you can never
- 43:52function at a high level capacity, right, if you don't
- 43:57have certain ease right at that high level.
- 44:01And what are the ES education, exposure, enlightenment and
- 44:07experience. So fees ease right from the
- 44:14level of capacity that a person can perform at intellectually.
- 44:20So a lot of times when I see people acting in a sub, you
- 44:26know, optimal way or an undesirable way, I, I, I feel, I
- 44:31feel sorry for them. I feel empathy for them because
- 44:34the joke is not on me. The joke is on you, right?
- 44:37You get into an elevator, you, you try to be polite, you try to
- 44:41be respectful. You see a greeting and you know,
- 44:46some people just ignore you as though you don't exist.
- 44:48And you look at yourself, Am I, am I invisible now?
- 44:52It's crazy. Like what you said, people, you
- 44:55know, lack empathy in this age and time.
- 44:59I'm a very, very big enthusiast of AI and I'll just make the
- 45:04joke that it's like my parents knew the assignment.
- 45:07My initials are AII team. All I see there, because, you
- 45:11know, I've used AIA lot, you know, in terms of enhancing
- 45:15efficiency for my company and of course green this podcast.
- 45:19In university, I studied economics and that is, you know,
- 45:23the social sciences faculty and I was, you know, opportunity to
- 45:27take courses in psychology and sociology.
- 45:30You know, psychology is the study of the human mind and
- 45:33sociology is the study of human social behaviour, social
- 45:37interactions. And it gave me that privilege to
- 45:40be able to, you know, stand back and be objective, you know, to
- 45:45observe and analyse, you know, absorb information like a
- 45:49sponge. And like I told you before we
- 45:51started the podcast, when I was in secondary school, I was just
- 45:56pure sciences, a student. So I understand that background
- 45:59from chemistry to biology to physics, and adopting the
- 46:04empirical method for reasoning. When you adopt the empirical
- 46:10method of reasoning, it makes you objective, right?
- 46:13And that's why I think in terms of basic education, people
- 46:17should I don't know what the policy makers are doing the
- 46:21people first to study the sciences, right, Because, you
- 46:25know, still part of the ease if your education is, you know,
- 46:30left wanting, it's difficult to have you operate at a high level
- 46:37of critical reasoning. You know, philosophy has a
- 46:42branch called logic for a reason, deep logic, arguments,
- 46:46critical reasoning. And when I think about the high
- 46:50quality of education that I am privileged to have, it has made
- 46:54me to be able to operate at a high level in in society.
- 47:01I've been privileged to, you know, speak with brilliant
- 47:03minds, you know, of my own time. And you know, you look at my
- 47:06body of work, having people from different works of life, from
- 47:10athletes to businessmen to scientists like yourself, to
- 47:14healthcare practitioners. And this is a guy from finance.
- 47:18I have this debate, right, about the nature versus nurture.
- 47:25And I want to put it on you right now because you are the
- 47:29science guy. What do you think?
- 47:32Or is there like a balance or hybrid or what's the bigger
- 47:37influence in terms of people's behaviours?
- 47:42Is it nature or is it nurture? It's, it's got to be both.
- 47:47It's always both, in fact. Well, actually, no, that's not
- 47:49true. It's not always both.
- 47:50So let me let me give you an example.
- 47:52Let's say, let's talk about empathy, right?
- 47:55Let's say you are born with a genetic change that
- 48:02fundamentally alters how parts of your brain work.
- 48:05And let's say those parts of your brain are related to
- 48:08empathy. You will probably be diagnosed
- 48:11at some point in your life with a condition called psychopathy,
- 48:15where you are, you lack empathy. That change was driven by a
- 48:22genetic mutation that happened to you when you were a cluster
- 48:25of cells, before you had a brain, you know, before you were
- 48:28anything, before you encountered the world.
- 48:31And it it required that you will develop with an absence of
- 48:35empathy. That's very much nature, right?
- 48:39And that genetic change could happen to anybody.
- 48:41It's just, you know, in that case it would be de Novo.
- 48:43It's new, it happens randomly, spontaneously, very much nature.
- 48:49But you could also not have that genetic change and be born with,
- 48:53you know, a brain that is like the average person's brain, but
- 48:57be born to parents that are super unresponsive to your
- 49:02emotions. They don't show you, hey, this
- 49:04is how you react, right? Like you.
- 49:07And then it starts with very young children emotional
- 49:09mirroring, right? You smile and you laugh in the
- 49:12baby's face and the baby starts laughing and smiling in your
- 49:15face, right? And then when you, when the baby
- 49:17smiles, oh, the parents start smiling and laughing too,
- 49:19because it's cute, right? This like emotional mirroring
- 49:22and the parents responsiveness to the child, to their emotions
- 49:27is a big part of shaping empathy.
- 49:29That's nurture, right? That's pure experience.
- 49:32And so you could be born with the exact same genes but have
- 49:36parents that are super responsive to your emotions or
- 49:39super unresponsive to your emotions, end up with completely
- 49:43different ways of perceiving the world and and experiencing
- 49:47empathy and experiencing other people's emotions.
- 49:50So it's gotta be both. It has.
- 49:51It's always both. I mean, and what, and basically
- 49:54the way I see the, the role of genes is that they're sort of
- 49:57like a funnel, right? So it's like you could be
- 50:00anything, right? You could be anywhere out here.
- 50:02I'm not sure how much my, my body.
- 50:04You can actually see my hands are wide or if anyone's
- 50:06listening, I have my hands wide out.
- 50:08You could be everybody could be anything, but your genes narrow
- 50:12that range to you. You could be something like
- 50:14this. And and it's for every trade,
- 50:16right? Your height, you might be
- 50:17anywhere between 5-6 and five eight, because that's the height
- 50:21of your genetics, right? Or your empathy.
- 50:24You might be really empathic or you might be sort of empathic,
- 50:26but you're probably not gonna be not empathic or you're how how
- 50:29sociable you are. You're probably gonna be not
- 50:32very extroverted. You'll probably be more
- 50:33introverted because that's what your genes, how they have shaped
- 50:36your brain. That's all nature.
- 50:39But then you're born and you encounter the world and any of
- 50:43those things can change. I mean, maybe not height.
- 50:44I don't know about height, if that can change, but you know,
- 50:47like your your introversion, extroversion, right?
- 50:50When you're young, you might your it might just so happen
- 50:54that your parents best friends had kids the same age as you.
- 50:59And so when from when you were a little kid, you always hung
- 51:01around others. And so your nurture, your
- 51:03experience caused you to start favouring social interaction.
- 51:07Even though your parents might be introverts, suddenly you had
- 51:10experiences that shaped you. And, and I think that we are all
- 51:14this just beautiful, unique concoction of our experiences
- 51:21and where we come from, our lineage, our parents, their
- 51:25parents, their parents, their parents, this all is just
- 51:29uncontrollable. And, and As for the argument of
- 51:33like free will versus determinism, you know, I think
- 51:36by the time our genes narrow us to that range and then our
- 51:41experiences narrow us even further, there's a very small
- 51:45area of wiggle room that we are basically able to operate
- 51:49within. And so that's kind of the Robert
- 51:52Sapolsky determinism perspective.
- 51:55And, you know, I, I believe in that.
- 51:58I, I believe that we have free will, but I believe that our,
- 52:00our ability to exercise that free will is very much
- 52:04restrained by who we are and who we are comes from what we've
- 52:07been through and what we, where we come from.
- 52:09And you know, it's interesting because I'll have, I'll have
- 52:12this happen to me all the time where like, you know, I'll, I'll
- 52:15film a video for Instagram 'cause I post like short form
- 52:18videos on, on social media about neuroscience.
- 52:21I'll, I'll press play and I'll start talking and I'll record
- 52:24myself. And then I, you know, couple
- 52:27days pass by and I look back at the video or I maybe I don't
- 52:30even look back at the video. And I'm like, yeah, you know
- 52:32what? I, I don't, I don't think I like
- 52:33that take. Let me redo this video.
- 52:35And so I'll, I won't have a script.
- 52:37I'll refilm the exact same video and then a couple days later
- 52:40I'll come back and I'll compare the 2 and it'll be like the
- 52:42exact same video. Like I did not watch the video
- 52:45before. I was not at all influenced, but
- 52:48the wording, the way I presented it, the way I move my arms, it's
- 52:51like I only have so much wiggle room to act within.
- 52:55And when I'm talking about it, you give me the the prompt of
- 52:58talk about this topic. I'm probably gonna say almost
- 53:02the exact same thing most of the time because it's who I am.
- 53:06And I might feel like I have free will when I'm exercising
- 53:09that, but it's, it's like determined by who I am.
- 53:12And so it's got to be both. It's always both.
- 53:15You know when you have an identical twin, and of course
- 53:19the this has happened in real life.
- 53:21You have identical twins who maybe by way of life
- 53:25circumstances grew up in different environments.
- 53:29They typically have different attitudes, but tend to have like
- 53:33similar talents. Interesting.
- 53:38And you know, for me, I feel like the talent is the nature
- 53:43and the attitude is the nurture. Interesting.
- 53:47And there's something I always say on this podcast, hard work
- 53:52beats talent when talent does not work hard.
- 53:57But when you're talented and you work hard at the same time, you
- 54:03become unstoppable, unbeatable. You know, I tell people about
- 54:07how growing up I felt like I was talented at music and talented
- 54:13at speaking. The very first two books I ever
- 54:17bought with my own money were books by Bill Kanecki, How to
- 54:25Win Friends and Influence People and The Art of Public Speaking.
- 54:29So people because of the nature of the education that I have in
- 54:36finance, you should think oh why are you going into the media?
- 54:41They you don't know Jack about me.
- 54:46I grew up in a place in Nigeria called Lagos and just right at
- 54:50the back of my parents house was Dark Communications, that is the
- 54:57company that owns the very first independent radio and TV station
- 55:04in Nigeria. Think about it right that just
- 55:09where the whole dream of broadcasting came about.
- 55:14So I was exposed very early to, you know, the media and that was
- 55:21a very big influence. You now go to university, become
- 55:25a finance guy. Even in university I used to,
- 55:29you know, MC events. I did MC an event for a when I
- 55:36say a concert very in this this guy that's really famous right
- 55:42now in Afrobeat. His name is Shake.
- 55:45He went to my university and you know, it's it's crazy how people
- 55:48have potentials. And I never knew he was going to
- 55:51be that that famous going into the future.
- 55:53And I used to MC seminars, conferences and, you know, left
- 56:00university. But there's something we do in
- 56:03Nigeria called the NYSE, the National Youth Service Corps.
- 56:06It's like a one year service to your government, a paramilitary
- 56:10training. When I was on the camp for that
- 56:13service, I was on something called the Orientation
- 56:17Broadcasting Service. Now you see the storyline.
- 56:22I've always taken communication very seriously and I got into
- 56:25PwC, second largest accounting firm in the world.
- 56:29I was always involved in, you know, the trainings, teaching to
- 56:35clients, right, Anything involved in communication.
- 56:39I got into KPMG here in the UK, find a way to always be involved
- 56:44in presentations and you know, people not think, oh, you're a
- 56:51finance guy, you shouldn't be in the media.
- 56:53But they don't realise that I had made that conscious effort
- 56:57over time. Oh, I, I think I left something
- 56:59out. I was also involved in teaching.
- 57:01I was a lecturer for professional accounting
- 57:05students, right. That actually helped to refine
- 57:08my approach. And of course you are a teacher
- 57:10as well. You'd agree with me that the
- 57:13highest level of communication is teaching something.
- 57:18Of course, you need to understand it better than the
- 57:22average person before you can teach it.
- 57:25If you if you think you want to communicate something, teach it.
- 57:30And then you know that, OK, that's the highest level.
- 57:34Yeah, or if you want to think you want to, if you want to
- 57:36learn something, right, that'll happen to me.
- 57:38I used to do that in my PhD all the time.
- 57:39I would read a paper and the way I would test myself, do I
- 57:44actually, did I learn it? Did I actually figure out what
- 57:47they were doing is I would, I would ask myself, all right, how
- 57:50would I teach this to someone? And you start telling, you know,
- 57:53you start imagining. OK, so this is what you know,
- 57:55this is what the the study found.
- 57:56And and you imagine, oh, well, they're probably gonna ask me
- 57:59that question. And it's like, oh, shit, I don't
- 58:01know the answer to that. You know, let me go back and and
- 58:03study some more and see if I can figure that.
- 58:05Out. Absolutely.
- 58:07Absolutely. When they ask you questions, it
- 58:08makes you think about the concept from another
- 58:11perspective, and thinking about it from another perspective
- 58:16helps you to understand it better.
- 58:18Yeah. And by the way, on this, I meant
- 58:20to say this in the beginning. We're talking about like young
- 58:23people and, and learning and stuff.
- 58:25Never be afraid to ask questions.
- 58:27That is like the best thing you could possibly do.
- 58:30I used to always be afraid, oh, if I'm gonna ask this question,
- 58:34I'm gonna look stupid. They're gonna, they're gonna
- 58:35know. Obviously, I don't know the
- 58:37answer to this and I'm gonna look so stupid.
- 58:40You don't look stupid. What looks stupid is if you
- 58:42don't ask the question and then five years later, you definitely
- 58:45should know that information, but you don't know it because
- 58:47you never asked. And now you do look stupid
- 58:50because you're in a position where you should know it for
- 58:51sure when you're learning and you're just getting started.
- 58:53Or honestly, it doesn't even matter if you're just getting
- 58:55started, if you ask people to help you, it shows humility and
- 59:01it also shows respect and it just shows vulnerability and
- 59:04trainability. And these are all great traits
- 59:06that you want. Never be so worried about
- 59:08looking smart or looking a certain way that you that you
- 59:10don't ask for help. Super, super important.
- 59:13But there's also another point that I wanted to comment on
- 59:17earlier. You talked about the importance
- 59:19of learning the, the nature of empirical study, scientific
- 59:22study, right? And this is how I live my life.
- 59:26I don't know if it's because I'm a scientist or not, or if it's
- 59:29just the way I think. But like this is how I think
- 59:32about everything. It's like I want to know the
- 59:34answer to something. Show me the data.
- 59:36Let me what what are the data say?
- 59:37And so like, here's an example of this.
- 59:39Evidence based. Yeah, like you, it just, it will
- 59:43take your life like you want to live like a genius.
- 59:45Like I always like to motivate people with this.
- 59:47It's like, OK, if you want to live like a genius, use science
- 59:50in your daily life because it will.
- 59:52It'll help you just understand the world.
- 59:53Here's an example. So the other day I went to make
- 59:57a cup of water from my refrigerator, and I have a part
- 1:00:02that dispenses water, and I have a part that makes ice.
- 1:00:06And so I make this cup of ice water and it's cloudy.
- 1:00:08And I think, oh man, OK, something's wrong.
- 1:00:11It's either the water or it's the ice.
- 1:00:14How can I get to the bottom of this?
- 1:00:15Well I can fill 1 cup with just water and I can fill 1 cup with
- 1:00:19just ice and wait for the ice to melt and see which of these cups
- 1:00:23is cloudy. Like yeah, this may be seem
- 1:00:25obvious but what's the reason I bring this up and explain this
- 1:00:28is because what empirical study and following the data does is
- 1:00:33it unlocks the ability to take your emotions out of it.
- 1:00:36Because I, I may not want my ice dispenser to be making cloudy
- 1:00:42water, cloudy ice, because I want a pain in the ass.
- 1:00:45Now I have to fix my ice dispenser.
- 1:00:47I just call it a handyman. I have to come pay all this
- 1:00:49money to get it fixed. It would be much easier if if
- 1:00:51maybe you know, I accidentally the cup was dirty, it wasn't
- 1:00:54properly cleaned by the dishwasher or something that
- 1:00:56doesn't cost me money. It would be so much more
- 1:00:58convenient. But if I do this experiment and
- 1:01:00I get the answer, my emotions are out of it.
- 1:01:03I'm not thinking about, oh, I really, I don't want it to be
- 1:01:05this. It's like, that's what it is and
- 1:01:06I just deal with it. And I think trying to just
- 1:01:09follow the evidence makes life so much easier because you're
- 1:01:14not like you're never, you're never living at a knowledge
- 1:01:17deficit. You're never trying to operate
- 1:01:19in circumstances where you don't know everything.
- 1:01:21If you have a grip of what's going on, it just makes it much
- 1:01:25easier to make decisions and to, I don't know, move forward in
- 1:01:28whatever direction you're going, whether that's solving a problem
- 1:01:30or just trying to figure out which, you know, should I go to
- 1:01:33this school or should I go to this school?
- 1:01:34It's like, well, look at the data.
- 1:01:36You know what, what's the percentage of people from that
- 1:01:39school who land the job that you're interested in?
- 1:01:41You know, like that kind of stuff is so important.
- 1:01:43And another thing that's happening in America is we're
- 1:01:46suffering from this truth decay. That's what people call it,
- 1:01:48where we're basically losing sight of what's true, right?
- 1:01:51What is fact, What is information, what is reliable?
- 1:01:54What's fake news, right? We're, we're getting, it's
- 1:01:56really hard to know what's real. And that's real scary because
- 1:02:00how do you live a life and steer yourself and take care of your
- 1:02:04family if you can't trust information and we can't
- 1:02:07fundamentally agree on what is fact.
- 1:02:09So search for fact wherever you can and and use it to your
- 1:02:12advantage because you'll be better.
- 1:02:14You'll be more advantage than a lot of people who who don't rely
- 1:02:17on fact these days. I very much appreciate what
- 1:02:22you've just said of a curse. Spent about 8 years of my life
- 1:02:27in accountancy practise and what was I doing?
- 1:02:30I was an auditor and what the auditors do you know, verify
- 1:02:34information, you know, make professional decisions and
- 1:02:42opinions based on what and verified facts and you know,
- 1:02:46this has actually like followed me in my life and everything
- 1:02:50that I do. I followed the data and you know
- 1:02:53when the data you know, in order we say something.
- 1:02:56The most compelling form of audit evidence is reliable third
- 1:03:05party evidence. It's not about me saying it when
- 1:03:10I reached out to you and you know was giving you updates,
- 1:03:14right? I give you the updates from
- 1:03:17where leasing Notes and Leasing Notes is the Google of podcasts,
- 1:03:22right? Listen, Notes is the world's
- 1:03:24number one podcasting database with a public verification and
- 1:03:29Leasing Notes says I am global to top 2.5%, right?
- 1:03:34I did not state that claim. You could go verify it, right,
- 1:03:37Right. It was easy for you to believe,
- 1:03:40right? But if I came up and said I am
- 1:03:43global so and so you asked me, who gave you that certification?
- 1:03:49Yeah, based on what, right. So it's it's it's, you know,
- 1:03:54very important that, you know, we actually verify information.
- 1:03:58People say, OK, somebody came and told me the other day and
- 1:04:02said Nigeria has so and so and so numbers.
- 1:04:05And I'm like, oh, where did you get that info from?
- 1:04:07Then they were like, I saw it on TikTok, like, OK, it, it's, it
- 1:04:13speaks to what I have said on this podcast before.
- 1:04:17We are in an age of the height of artificial intelligence, but
- 1:04:22unfortunately, we are also in the age of the height of human
- 1:04:27foolishness. So I am not the neuroscientist.
- 1:04:30You're the neuroscientist. Why?
- 1:04:32Why is this happening? What?
- 1:04:35What's responsible for this? For for you mean for the lack of
- 1:04:42trust in data. No, no.
- 1:04:45So The thing is this, right, I'm 3033 years old, so I'm a
- 1:04:49millennial and I remember growing up, you know, back home
- 1:04:53in Nigeria, if wanted to get like important information, a
- 1:04:58lot of times you need to go to the library, dig into, you know,
- 1:05:01that rabbit hole of books and over time came Google, you
- 1:05:08search and search and search different, you know, databases,
- 1:05:11check for the ones that are reliable.
- 1:05:13Now you have the likes of chat, cheapity, cloudy eye,
- 1:05:16perplexity, you know, on and on and on, right?
- 1:05:19And information is easily and widely available right now in
- 1:05:27this agent time. Yet people still easily spread
- 1:05:31false information, and people are easily misinformed.
- 1:05:34And people find it very easy right to spread information that
- 1:05:40is false. But why?
- 1:05:43I mean, you got to look at the incentive structure, right?
- 1:05:46So back in, I don't know, let's say 2000, the year 2000, right?
- 1:05:54If a website comes out on the middle of whatever, you know,
- 1:05:58they can buy a URL and they post a website and it contains fake
- 1:06:02information, what's the point of doing that?
- 1:06:04You know, no one's going to read your website, no one's going to
- 1:06:06trust your website, right? There's no incentive to do that.
- 1:06:11But now there's so many incentives built into misleading
- 1:06:15people. And one of those it starts with
- 1:06:18social media that the development of these
- 1:06:21recommendation algorithms where now if you post juicy enough
- 1:06:26content that gets people to feel some sort of emotion, that is
- 1:06:30probably going to be shown to people who don't follow you,
- 1:06:33right? We have this like TikTok start
- 1:06:35of this and now it's on Instagram and now it's on
- 1:06:37YouTube and all sorts of places where you just sit back, swipe
- 1:06:41and it just feeds you content that it thinks you're going to
- 1:06:43like. You don't have to follow them,
- 1:06:44right? And so for everybody on the
- 1:06:46other side of that equation, the person cooking up the meals that
- 1:06:49you're the, you know, the content that you're eating and,
- 1:06:51and consuming, you have so much incentive to do whatever it
- 1:06:56takes to get in front of that person.
- 1:06:58Because if you get more followers and you get more
- 1:07:00likes, then you get brand deals and you get sponsorships and you
- 1:07:03get fame and you have all these incentives built into simply
- 1:07:07getting attention. And what's the best way to get
- 1:07:09people's attention to make them feel some sort of strong
- 1:07:12emotion? And oftentimes what we see
- 1:07:14nowadays is that strong emotion is shock or disbelief or rage,
- 1:07:19negative emotions and things that either fear exactly things
- 1:07:23that make you step back and say, whoa, wait a minute, you know,
- 1:07:26that person's doing something horrible.
- 1:07:28I despise that person. Or you know, or what?
- 1:07:31Whatever it is, social media creators have every reason to
- 1:07:38say anything whatever, like where you can make up is always
- 1:07:42going to be more interesting than the truth.
- 1:07:44Because I could tell you, oh, you know, what's the prefrontal
- 1:07:48cortex? Well, as neurons, and they
- 1:07:49signal with glutamate and GABA, whatever, that's no one cares.
- 1:07:53Or I can tell you in the prefrontal cortex, you know,
- 1:07:55your neurons send around sour cream.
- 1:07:58And so the more sour cream you eat, the more effective your
- 1:08:01brain works. Like you can say whatever.
- 1:08:03And if people believe it, then you will start getting
- 1:08:05attention. And that's really dangerous
- 1:08:07because there's also no fact checking online.
- 1:08:10There's no sort of regulations around misinformation.
- 1:08:13And so, yeah, a big part of what I do is I actually try to go out
- 1:08:16and find videos that are spreading misinformation.
- 1:08:19And usually it's not very hard to find them because they have
- 1:08:21millions of views. And I can just, you know, people
- 1:08:23will often send them to me as well.
- 1:08:25And if it's getting a lot of views, then I'll go out and I'll
- 1:08:27make a video where I or I debunk it where I explain, you know,
- 1:08:30here's what's wrong about this. And I, I always try and do it in
- 1:08:32a, a very polite and not condescending way.
- 1:08:36Nobody wants to hear a scientist in a white coat talk down to
- 1:08:40them and say you're wrong. And here's why.
- 1:08:43And you know, neither do I I didn't want that when I was
- 1:08:45studying, you know, I wanted to be understood.
- 1:08:47And So what I try and do is just basically lay out the facts and
- 1:08:51I take my emotions out of it just like I do in my daily life
- 1:08:53and just explain, oh, here, this is not right in basically the
- 1:08:57heroes of studies and, you know, believe whatever you want to
- 1:08:59believe. But here's the real evidence on
- 1:09:01it. Here's what this what the
- 1:09:02evidence in the data say. And, you know, I've been really
- 1:09:04fortunate to see that catch on and people seem to really
- 1:09:07respect that and appreciate it. And it just speaks to how
- 1:09:12inaccessible good information is.
- 1:09:14You know, the, the, the quality of the information that you get
- 1:09:17online about neuroscience and psychology.
- 1:09:19Speaking as a neuroscientist, it's horrible.
- 1:09:22It's garbage. There are some creators who you
- 1:09:25can trust that are real neuroscientists and, and
- 1:09:27researchers and they actually spread good information.
- 1:09:30For every one person like that, there's, I don't know, 10,000
- 1:09:34people who just start talking about neuroscience in the brain.
- 1:09:37And basically what they're saying is just not, it's not
- 1:09:39based on real science. It's based on something they
- 1:09:41read on a website or, you know, something that they
- 1:09:43misunderstood or whatever. And some of those people are
- 1:09:46just genuinely speaking from their heart and trying to help
- 1:09:50others and don't realise that they're wrong.
- 1:09:52And some of those people are intentionally misleading you
- 1:09:54because it benefits them financially.
- 1:09:56And that's the that's the scary part.
- 1:09:59So fast. It's like the case of the blind
- 1:10:01leading the blind. But I'll just say one thing.
- 1:10:04I think it's the responsibility of anybody consuming information
- 1:10:10to verify the source of the information.
- 1:10:13And it's really easy to know or to ascertain if the source is
- 1:10:19reliable or not reliable. So I think for the viewers, for
- 1:10:24the audience, it's something we should try consciously try to
- 1:10:29activate in terms of our attitude or our behaviour
- 1:10:32towards consuming information. And you talked about a prefront
- 1:10:37the, the, the cortex, right? I do have a friend, Maya.
- 1:10:41It can go in Abu Dhabi. Very, very obsessed with the
- 1:10:45prefrontal context. But before I ask the questions
- 1:10:49that she has sent to you, I am going to ask you a question that
- 1:10:52was sent to you by my partner. And she says this.
- 1:10:55She says. From your perspective, what's
- 1:10:57the most exciting or surprising discovery about the brain in
- 1:11:01recent years? We think for a minute, Oh my
- 1:11:03gosh, there's so many. Let me give you 1 from my book
- 1:11:06that So you know, when I wrote this book, so I I've been
- 1:11:09studying social behaviour as a neuroscientist for a decade now.
- 1:11:12But when I wrote Why Brains Need Friends, I was doing a bunch of
- 1:11:17research on, you know, what studies are out there and I
- 1:11:20learned a bunch of things. And this is one of the things
- 1:11:22that I learned that completely blew my mind.
- 1:11:25So when a mother is getting close to giving birth, she will
- 1:11:30produce pulses of oxytocin. And oxytocin is, maybe you've
- 1:11:34heard of it, the love hormone, right?
- 1:11:36People think of oxytocin. They think of bonding and
- 1:11:38partnership. And so when you hear that this
- 1:11:41oxytocin is being produced by the mother, you probably think,
- 1:11:44oh, that's her body and her brain getting ready to meet the
- 1:11:47baby and form a connection with the baby.
- 1:11:48But it turns out that's actually not the purpose.
- 1:11:51What's really happening is this oxytocin produced by the mother
- 1:11:55goes, flows into the baby and into the baby's brain and
- 1:11:59influences those brain cells and lowers their activity.
- 1:12:03And the reason that that's meaningful and that's that's
- 1:12:06happening is because when the baby is coming out of, you know,
- 1:12:11being born and it's passing through this tight canal, it's
- 1:12:14very likely that the baby is going to have to deal with some
- 1:12:18restricted blood flow and restricted oxygen.
- 1:12:21And so when when you have oxygen not being delivered to brain
- 1:12:26cells, brain cells can die. That's what a stroke is.
- 1:12:29And so how do you protect the baby's brain to make sure that
- 1:12:32brain cells start don't start dying when there's little oxygen
- 1:12:36flowing? Well, you reduce the activity of
- 1:12:38the brain cells. You reduce their demand to how
- 1:12:40hungry they are. It's like if imagine if you're
- 1:12:43you're swimming, you're treading water or you're drowning and you
- 1:12:46could hold your breath for longer, right?
- 1:12:48That's basically what it's doing.
- 1:12:49It's allowing these brain cells to stay alive for longer.
- 1:12:51And it's basically a neuroprotective system built
- 1:12:58into the mother, built into the bodies of human mothers and
- 1:13:02other animals too, to protect the baby and its brain on the
- 1:13:06way out. And I found that to be
- 1:13:07completely amazing because studying in this field, I had
- 1:13:09never heard about that fact before.
- 1:13:11That's not actually that recent. You did ask me recent, but to me
- 1:13:14that one's just like every time I I think about it, it's like
- 1:13:16it's mind blowing. Like when we are born, we are
- 1:13:19already protected by the ancient wisdom of biology that's built
- 1:13:24into us. Just incredible.
- 1:13:27Wow, that is, it's not just mind blowing, that's brain blowing
- 1:13:30like this. And it's yeah and yeah, I am
- 1:13:32going to go into the prefrontal cortex.
- 1:13:34Our questions shout out to Maya Ikango from Abu Dhabi.
- 1:13:40So number one is does the prefrontal cortex develop
- 1:13:46differently depending on gender? Oh man, that's a good question.
- 1:13:51You know, honestly, I can't say for sure.
- 1:13:53I remember seeing some studies on this like a couple of years
- 1:13:57ago and I don't think I ever really got to the bottom of it.
- 1:14:01I'm sorry, I can't give a definitive answer, but you know,
- 1:14:04hey, this is also one of those things where you don't want to
- 1:14:07look stupid asking and questions.
- 1:14:10What kind of neuroscientist wants to come on a podcast and
- 1:14:12say, I don't know the answer? The answer is an honest one, one
- 1:14:16that will actually say, look, I don't you know, this is the you
- 1:14:18have reached the limits of my knowledge.
- 1:14:20And I think that's also, by the way, a good sign of who you
- 1:14:23should trust. If you ask someone a question
- 1:14:25and they always have the answer like this.
- 1:14:27Absolutely. I only see something you know.
- 1:14:29I'm a professional, right? But I don't know all the
- 1:14:33answers. Yeah, I've had myself and that's
- 1:14:35OK. In knowing we had to get the
- 1:14:37answers if I need to. Exactly.
- 1:14:39Exactly. Yeah, I could find that answer.
- 1:14:41Maybe I'll I'll check it out and I'll I'll.
- 1:14:42Send it. Yeah, of course.
- 1:14:44So that means that automatically we should book a Part 2 for
- 1:14:48this. We can.
- 1:14:50So now you're gonna come back. You can come back with an
- 1:14:52advanced. Cortex Edition.
- 1:14:55Yeah, Prefrontal cortex edition. You said you're ready.
- 1:14:58So #2 is does a stress or trauma inhibit its function,
- 1:15:05particularly before it's fully developed?
- 1:15:09Interesting, yes, so I do know the answer to this one.
- 1:15:13Stress does influence the function of the prefrontal
- 1:15:16cortex. It's quite interesting, also
- 1:15:19based on some research done in my PhD lab.
- 1:15:22So when in in short term stress, couple days, couple hours,
- 1:15:27whatever, the the prefrontal cortex actually gets more
- 1:15:30effective. It becomes better, like the
- 1:15:32cells are are interacting more efficiently, which makes sense
- 1:15:35because you have to deal with some challenge.
- 1:15:36You need to be locked in right? You got to be capable of
- 1:15:39processing the challenge. But with chronic stress over
- 1:15:43time goes for weeks or months, the prefrontal cortex, the
- 1:15:46function goes way down and the brain cells actually become less
- 1:15:49effective at interacting. What, what's really happening
- 1:15:51amazingly, is that the, the receptors on the neurons where,
- 1:15:56you know, brain cells are sending messages to each other,
- 1:15:59the receptors start going away. And so the brain cells actually
- 1:16:03have trouble communicating with each other.
- 1:16:06And, and basically what that amounts to is that you're
- 1:16:07processing power and your computing power goes down South.
- 1:16:11Chronic stress is bad. As for the timing, I don't think
- 1:16:15it can, you know, impair, you know, I would say in the context
- 1:16:21of like normal ranges of stress will not necessarily change the
- 1:16:26function of your prefrontal cortex long term, but like
- 1:16:29traumatic stress, like PTSD, you know, really traumatic
- 1:16:33experiences. It could I've been.
- 1:16:34I believe there is evidence that that it does alter the the
- 1:16:37function of the prefrontal cortex.
- 1:16:39Interesting. So there's a third question, and
- 1:16:43that is how is the prefrontal cortex different from other
- 1:16:48parts of the frontal lobe? I mean, the prefrontal cortex is
- 1:16:53the most like evolved. It's like the, it's the, it's
- 1:16:56the reason you have the frontal cortex and then you have the
- 1:16:59prefrontal cortex. The prefrontal cortex is even
- 1:17:01more towards the front. And there's this general idea
- 1:17:04that like the further away from the brain stem you get and like
- 1:17:08this base level, the more evolved and, and fancy the brain
- 1:17:13area is. And so the prefrontal cortex, it
- 1:17:16just, it has a lot of amazing functions that aren't
- 1:17:18necessarily seen in the the frontal cortex, like much more
- 1:17:20higher level cognition and be able to understand people and do
- 1:17:24things that make us human really.
- 1:17:26But, but The thing is the, the prefrontal cortex is also like
- 1:17:30every brain area. It's like very distributed.
- 1:17:32There's all these different nuclei and brain and sections,
- 1:17:35you know, within the prefrontal cortex there's the dorsolateral
- 1:17:38prefrontal cortex and all these different subsets of areas that
- 1:17:41are all involved in different things.
- 1:17:43And you know, the brain is just immensely complicated.
- 1:17:47But without a prefrontal cortex, you know we would not be as high
- 1:17:50functioning animals. I like that.
- 1:17:54I always say that human beings, we are animals, it's just that
- 1:17:59we are higher animals, right? And of course, we have the
- 1:18:01animals with the highest level of IQ.
- 1:18:03That is why we are able to dominate.
- 1:18:05So #4 is the prefrontal cortex is sometimes called the CEO of
- 1:18:11the brain. Why is that and do you agree
- 1:18:14with that? Interesting You could say that
- 1:18:21you, I guess, I mean there's a couple different CEOs of the
- 1:18:23brain and actually the nucleus accumbens that I mentioned
- 1:18:26earlier in the context of MDMA is also one of those.
- 1:18:29But I would say, yeah, I guess the way I kind of think about
- 1:18:31the prefrontal cortex is it's like the babysitter of the
- 1:18:33brain. You have all these brain areas
- 1:18:35that are just like impulsive and they're doing their job.
- 1:18:37And your prefrontal cortex is, is often like shutting off those
- 1:18:40impulses and being like, wait a minute.
- 1:18:42But, you know, before we slap this person in the face, let's
- 1:18:45think about this for a minute, you know, and it's kind of
- 1:18:48babysitting and keeping those brain areas in check.
- 1:18:51So yeah. And many, many, it is the CEO,
- 1:18:53but I like to think of the the CEO of the brain sort of as the
- 1:18:56nucleus accumbens, because the nucleus accumbens is really in
- 1:18:59charge of like decision making or not in charge of it.
- 1:19:01But it has a major role in like deciding what things we pursue
- 1:19:05and what actions we do based on how much they benefit us.
- 1:19:09And you know, I think that's kind of like the role of the CEO
- 1:19:11really. So is it the CEO or the CEO?
- 1:19:16I feel like the, the, the, the nucleus to Cummins is the CEO
- 1:19:20and the prefrontal cortex is like the executive board, like
- 1:19:23the, you know, you have a board of direct or a board that's like
- 1:19:25steering the company in the right direction.
- 1:19:28I feel like that's sort of those two are combining to to make
- 1:19:31things work properly. OK, interested stuff.
- 1:19:36So this particular friend of mine, Maya, she she's very
- 1:19:40obsessed with the prefrontal cortex.
- 1:19:42And anytime she sees a person acting, you know, in an abnormal
- 1:19:48way, she just says, oh, that person's prefrontal cortex is
- 1:19:51not properly developed. And she's told me before that
- 1:19:55the prefrontal cortex actually fully develops at the age of 25.
- 1:20:01Is is is that true? Yeah.
- 1:20:04The prefrontal cortex, whether it's there's definitely not like
- 1:20:06a you, you're 25, it's done. It's not really like that.
- 1:20:11It's more of that, you know, as you're getting older, your
- 1:20:15prefrontal cortex is continuing to be shaped by your
- 1:20:17experiences. That's really what that whole
- 1:20:21like your prefrontal cortex isn't done until 25 means.
- 1:20:24It means that unlike other brain areas, your Pfc remains flexible
- 1:20:29as you get older. And so, you know, it may not, it
- 1:20:33may be 25 that you kind of get to that point or maybe a little
- 1:20:37bit later, you know, it doesn't really, it's not like a firm
- 1:20:41thing that it's like boom, 25, you're done.
- 1:20:47So great news, we actually recently got the brand deal, the
- 1:20:53sponsorship and of course our partnership with Betterhelp,
- 1:20:57which is the world's leading online therapy brand.
- 1:21:01So I'd like to real quick, when I say your brain, pick the brain
- 1:21:06of a neurosurgeon on the importance of therapy and what
- 1:21:10do you think about online therapy?
- 1:21:13Oh, I mean, I think like therapy is huge, you know, I, I see a
- 1:21:17therapist proudly. I think more people should be
- 1:21:20proud about the fact that they do see a therapist.
- 1:21:22You know, it's like people are really eager to share that they
- 1:21:25go to the gym, right, 'cause it's like going to the gym is
- 1:21:28seen as this good thing. It's like, oh, you're working on
- 1:21:30your body. Like good for you.
- 1:21:31You know, therapy is working on your brain.
- 1:21:33It's like you're, you're going to the gym for your brain,
- 1:21:35right? You're working on your mood,
- 1:21:37you're trying to improve your well-being, you're trying to
- 1:21:38grow. And so, you know, I have no
- 1:21:40shame in sharing that I go to see a therapist and, you know,
- 1:21:44and some days I go and I'm like, honestly, I got nothing to talk
- 1:21:46about right now. Like everything's good.
- 1:21:48I'm, I feel good and that's fine.
- 1:21:49You know, sometimes you go to the doctor and you're like,
- 1:21:51everything's cool. But other days I'm like, Oh my
- 1:21:53gosh, thank goodness I have this session because it's really
- 1:21:55important. So I, you know, I think, I think
- 1:21:57therapy is obviously important and there's obviously tonnes of
- 1:22:00research showing that it's effective and helpful.
- 1:22:03Having a good therapist matters. And and also, you know, As for
- 1:22:07the online component, you know, I prefer generally, you know,
- 1:22:11when possible in person. But but for a lot of people in
- 1:22:16person has a bunch of problems. One, it's less accessible.
- 1:22:20Yeah, sometimes it's it's not easy to get to a place like, you
- 1:22:23know, you might not, you might be in the little in the middle
- 1:22:24of a therapy desert where you don't have access to a
- 1:22:27therapist. You know, if that if that's true
- 1:22:29or you have access to therapists, but you don't really
- 1:22:32enjoy any of the therapists nearby.
- 1:22:33So that's another benefit. And the other thing too, is also
- 1:22:36when you have a therapist and you have to go into the office,
- 1:22:38you may not feel comfortable going into the office if you're
- 1:22:41if you're not a person who's proud to be in therapy and
- 1:22:44you're worried that you might see others.
- 1:22:45So I think, you know, what was it like?
- 1:22:46Betterhelp are great. I mean, the fact that you can
- 1:22:48see a therapist online is like, that's a new thing for humanity.
- 1:22:51I think it's a good thing. I absolutely would.
- 1:22:56I say I appreciate the kind of work that better help out does.
- 1:22:59It's, it's interesting, you know, when I look at my body of
- 1:23:01work, I've seen a lot of videos wherein I have, you know, spoken
- 1:23:06very heavily and assessively about the importance of therapy
- 1:23:11and having better help reach out to me to, to be a brand
- 1:23:15ambassador or to be a partner feels like a validation for what
- 1:23:19I stand for. And you know, it's really great
- 1:23:22as a creator to, to represent a brand that aligns with your
- 1:23:26philosophy. I think that's the best form of
- 1:23:29partnership. Let's talk about your book.
- 1:23:32It's, it's coming out very soon, right?
- 1:23:33And of course, again, I once assigned, you know, a copy of
- 1:23:37your book. It's interesting.
- 1:23:39You got a book that's similar to yours, right, Right here by
- 1:23:41Professor Bruno Signaco. He gave me this book and of
- 1:23:45course, he was on the podcast earlier this year and did sign
- 1:23:49the book. So I would appreciate your your
- 1:23:52autograph, you know, your celebrities of.
- 1:23:53Course, I would love to. OK, yeah, your book, what is it
- 1:23:59about? And of course, what are you
- 1:24:01trying to achieve with it and why should the audience buy the
- 1:24:05book? Yeah, well, the book's called
- 1:24:07Why Brains Need Friends, and it's, as the title suggests,
- 1:24:10it's about the neuroscience of social interaction and basically
- 1:24:13what we get from social behaviour, social connection.
- 1:24:17And you know, I think the reason I wrote the book is because
- 1:24:19there are all these stats out there that we're becoming more
- 1:24:22isolated. We're not spending time with
- 1:24:24others as much, and that's often framed as a very negative thing.
- 1:24:28And it is. But I don't think people fully
- 1:24:31appreciate the significance of what we actually stand to lose
- 1:24:34from being isolated and what we actually stand to gain from
- 1:24:38being socially connected. And so my goal with this book is
- 1:24:42to basically take all of this massive mounds of neuroscience
- 1:24:46research that has accumulated over decades and decades,
- 1:24:49including, I've been fortunate to contribute some of it myself
- 1:24:52and put it all in one place that the average person can read and
- 1:24:55understand and walk away and say, OK, I actually need to
- 1:24:59consider socialising as a fundamental component of my
- 1:25:03well-being. And I, I think people don't
- 1:25:05really do that enough, but it's important.
- 1:25:07It really makes a difference. And it's, it's just like going
- 1:25:09to the gym or having a clean diet or getting enough sleep.
- 1:25:12You know, it's one of those things that we really need to
- 1:25:13do. And, you know, I'm my goal with
- 1:25:16this book is, is that after reading this, people will
- 1:25:19appreciate that they will live healthier lives and they will
- 1:25:21live more connected lives. Because I am worried also about
- 1:25:25not just what the distance between us is doing for our
- 1:25:27health, but what it's doing for our societies.
- 1:25:30And I think that, you know, maybe by by helping people
- 1:25:33appreciate the biological significance for you, right?
- 1:25:38You are, as I've discovered through my life of falling in
- 1:25:41love with neuroscience, you are the person housed within this
- 1:25:45organ, right? And this organ loves interacting
- 1:25:48with others. It needs interacting with
- 1:25:49others. And so, you know, if I can get
- 1:25:52people to understand that the way I learned about it as a
- 1:25:55neuroscientist and came to appreciate it, I think we would
- 1:25:58have a much healthier, happier society.
- 1:26:00So I, I really, you know, and my, and my sort of secret quiet
- 1:26:03goal is I really, I want to sort of address this world that we
- 1:26:10find ourselves in where we do have less empathy.
- 1:26:13We're not really feeling disconnected with others.
- 1:26:15You know, I think if if people understood what it really means
- 1:26:18to be connected, then we wouldn't maybe be as quick to
- 1:26:21put our differences between us. Well, at this point, I feel like
- 1:26:26you should actually make me a brand ambassador for your book
- 1:26:29because it just completely aligns, You know, we are
- 1:26:33Nigeria. Big shout out to Nigeria.
- 1:26:35There's a flag of Nigeria. I'll just have my flag handy.
- 1:26:39The Yoruba people say carrying carp or yeni yeni.
- 1:26:42It means when we walk in groups, right?
- 1:26:45It brings honour to us as a people.
- 1:26:49If you want to go far, I walk alone.
- 1:26:51But if you want to go further, move with people, right?
- 1:26:54And, you know, there's a reason why the brain, you know, is in
- 1:26:57the head, Tell people because it's, you know, it's meant to be
- 1:27:01the leader of the body. If you know, the creator of the
- 1:27:05universe, you know, wanted the brain to be somewhere else, he
- 1:27:11would have put it somewhere else.
- 1:27:12So it's important that we ensure that we, you know, perform
- 1:27:17activities that would enhance that brain.
- 1:27:22Like you said, rightly said, we train our bodies, right?
- 1:27:25But a lot of times we don't do enough to train the brain.
- 1:27:28And I really appreciate your body of work.
- 1:27:31So the quick fire round are before we let you go, we, you
- 1:27:35don't get to see neurosciences every day.
- 1:27:36So let's milk out everything we can milk out of you.
- 1:27:39Quick fire round. 5 sharp questions, 5 sharp answers.
- 1:27:43Are you ready to rumble? Let's do it.
- 1:27:47I'm ready. OK, number one, what's the most
- 1:27:50misunderstood fact about the brain you wish everyone knew?
- 1:27:56Left brain, right brain. People have differences in how
- 1:27:59they behave and stuff, but studies show that there is not
- 1:28:02actually like the average person.
- 1:28:04You put them in a brain scanner, they don't have a dominant side
- 1:28:07of the brain. Yeah, I love that because I have
- 1:28:12personally been that person that has trained, you know, both
- 1:28:16sides, you know, and it's covered.
- 1:28:19It's it's kind of like a fallacy.
- 1:28:21It's basically how you train it. You can do anything you want to
- 1:28:25do and you can be anything you want to be.
- 1:28:27TikTok or Stanford lecture hall. Where do you feel you make the
- 1:28:32bigger impact? Gosh, TikTok, honestly.
- 1:28:37Welcome to the TikTok Generation One book or paper that changed
- 1:28:41the way you see neuroscience. For me to publish or to read.
- 1:28:47All right, that changed your perspective on on neuroscience.
- 1:28:52A book that I oh I see Behaved by Robert Sapolsky and also Live
- 1:28:58Wired by David Eagleman. Both both really good.
- 1:29:00Those are my top 2 favourite neuroscience books.
- 1:29:03Interests and stuff. I think we we should have that
- 1:29:05in the description section. Yeah.
- 1:29:07OK, so what's your go to practise for protecting your own
- 1:29:12mental health as a scientist creator?
- 1:29:16Exercise. Lifting weights.
- 1:29:19I love that. And of course, if you could
- 1:29:21collaborate with any scientist, past or present, who would it be
- 1:29:25and why? You know, I'm going to give a
- 1:29:28really kind of unexpected answer.
- 1:29:32There's a researcher named Doctor Ronald Duman.
- 1:29:35I applied to his lab to do a postdoc, and he is an amazing
- 1:29:39scientist, neuroscientist. And he passed away of a heart
- 1:29:43attack the year that I applied to be in his lab.
- 1:29:46And so I never got to work with him.
- 1:29:48And I think, you know, I have a lot of respect for him and his
- 1:29:51work and was sad to see and learn of his passing.
- 1:29:54And it would be awesome to collaborate with him.
- 1:29:58Rest his soul. Wow.
- 1:30:00And that is the end of today's session.
- 1:30:04There's something I always say, you know, gratitude is good
- 1:30:06attitude and when a person shares their life with you, the
- 1:30:09time with you, they share their life with you because the SI
- 1:30:12unit for measuring life is time. So for me, it's immense and
- 1:30:17intense gratitude, love and respect to you and of course to
- 1:30:21the audience. Guys, I have a neuroscientist
- 1:30:23here do the needful right? So go share like comments, you
- 1:30:30know, subscribe. If you don't do that, I think
- 1:30:33we'll we'll tell him to adjust your prefrontal cortex.
- 1:30:39Guys, you know, conceive belief, strive to thrive, and of course,
- 1:30:43go achieve. Before you run, do you want to
- 1:30:45leave a shout out to anybody before we say goodbye?
- 1:30:48I just want to shout out all the mentors that I've had that have,
- 1:30:51you know, trained me and, and showed me the way when I had
- 1:30:53questions. I think and you know, to the
- 1:30:55younger people, the people arising through their careers,
- 1:30:58find those mentors, you know, find those people who will
- 1:31:00answer your questions because those are your guides.
- 1:31:02Those are, you know, you will appreciate those people when you
- 1:31:06are in their seat helping the next generation.
- 1:31:08So I appreciate those who lend their hand to me.
- 1:31:11Wow, I love that curiosity. Curiosity to say it kill the
- 1:31:15cat. What satisfaction brought it
- 1:31:17back for me and Doctor Ben? It's goodbye and God bless you
- 1:31:21guys.