Latest / Wits & Weights | Strength & Fat Loss Over 40
The Latest GLP-1 Science on Muscle Loss, Fat Loss, and Weight Regain | Ep 461
What REALLY happens when you take a GLP-1 drug?
Your fat loss, your muscle, your heart, your inflammation, what happens to your weight when you stop, and long-term safety.
This episode covers body composition data from the 2026 semaglutide and tirzepatide trials, cardiovascular outcomes from SELECT and SURPASS-CVOT, inflammation findings beyond weight loss, weight regain patterns after stopping, and a 5-part framework to keep muscle on or off the drug after 40.
Plus the 2026 safety update and recent Alzheimer's and Parkinson's research for adults considering, taking, or tapering off a GLP-1…
The skinny
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