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Interorgan Insights: Preclinical insights into the pathophysiology of hepatopulmonary syndrome
In this podcast, author Maïté Verstraeten discusses the recently published review, ‘Preclinical Insights Into the Pathophysiology of Hepatopulmonary Syndrome’. The article examines the current preclinical understanding of hepatopulmonary syndrome (HPS), a serious pulmonary complication of liver disease characterized by abnormal pulmonary vascular remodeling, impaired gas exchange, and hypoxemia for which liver transplantation remains the only effective treatment. Drawing largely from findings in the common bile duct ligation rodent model, it highlights how complex liver–lung–gut interactions…
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