Twelve Hundred Patients, One Weekly Shot: The Mega-Trial Testing Semaglutide for Addiction

Recovery News | Mental Health & Addiction Recovery · Oct 23, 2026 · 4m

Twelve Hundred Patients, One Weekly Shot: The Mega-Trial Testing Semaglutide for Addiction

Funded by a $13.3 million Arnold Ventures grant, researchers at the University of Pittsburgh and Allegheny County will test once-weekly semaglutide, added to standard care for 52 weeks, in up to 1,200 adults with alcohol use disorder, opioid use disorder, or both — tracking employment, housing and criminal-justice outcomes alongside substance use.

Source

Major trial seeks to test semaglutide on adults with alcohol and opioid use disorder — News-Medical (Oct 13, 2026), reporting on the trial led by the…