
MitoQ, SS-31, Mitophagy, and Mito-Transplants: The Future of SCI Repair
Spinal cord injury is usually framed as a permanent structural problem — axons torn, connections lost, paralysis inevitable. This Deep Dive flips that assumption: the real long-term roadblock may be a secondary mitochondrial energy crisis that turns a helpful early scar into a toxic, permanent barrier. Using a 2026 Frontiers in Neurology review, Dr. Mike and Don unpack how ATP collapse, ROS signaling, failed mitophagy, and mtDNA “false infection” alarmsdrive chronic sterile inflammation, fibrotic hardening, and growth cone collapse. Then they explore the new therapeutic frontier…
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