Latest / Intellectual Medicine / Testosterone Uncovered: The Truth and Benefits Behind This Vital Hormone
Transcript
- 0:00Poor misunderstood testosterone. Why does conventional medicine
- 0:05hate you so much? Where's the source of all the
- 0:09fear and loathing? Maybe it emanates from our
- 0:12puritanical background. You know the idea of that.
- 0:16Testosterone is the devil. It gives men aggression and
- 0:20makes them horny. This is all the things that we
- 0:22hate about toxic masculinity. And it gives women beards.
- 0:26We all remember those East German swimmers back in the old
- 0:30Soviet Union days. Well, maybe we don't.
- 0:32But the point being that there's a lot of inbred cultural bias
- 0:37against testosterone, and it's been propagated through a lot of
- 0:41false thinking that has taken decades to break down.
- 0:46So let's look at it. Where is the risk?
- 0:51Testosterone is essential to life.
- 0:54Without it, we die. The species doesn't exist.
- 0:58There are testosterone receptors in every cell in the body.
- 1:02They're in the brain, muscle, the heart.
- 1:05Yes, they're critical for sex drive.
- 1:08They're critical for sexual function.
- 1:11But it's way more than a sexual hormone.
- 1:14Without adequate testosterone, your brain doesn't work as well
- 1:19as it should. The speed of conduction from 1
- 1:22neuron to the next slows down. You can end up with word finding
- 1:25difficulty, brain fog, irritability, short
- 1:30temperedness. You lose resilience toward
- 1:33friction. This is very common.
- 1:36Now you So we'll talk about the risk or the fear with regard to
- 1:41women. Testosterone is the most
- 1:43abundant female hormone. Yeah, that's right, ladies, you
- 1:47need your tea. Without it, you're going to get
- 1:50grumpy. Perimenopausal women.
- 1:53This is common. And you're like, I don't know,
- 1:5530s forties got kids are bugging you on one side, a career, a
- 2:00husband, maybe parents are getting sick and infirm.
- 2:03Life is stressful. You start to feel not so good.
- 2:07You start to feel a loss of sex drive.
- 2:10You gain a little weight in the midsection.
- 2:11You're not so happy. You get short tempered and
- 2:14irritable. I've heard the story
- 2:16generational from women that tell me about their mothers who
- 2:20morphed into something different.
- 2:22In many cases it's testosterone deficiency, and a little
- 2:28testosterone can change everything critical for women.
- 2:32What about cancer? What about breast breast cancer?
- 2:37It seems to me that people who are anti hormone love to tie
- 2:42these things together. Well, guess what?
- 2:44It doesn't work for testosterone at all.
- 2:48Doesn't work for estrogen much either.
- 2:49But the focus today is on testosterone for men and women
- 2:53and why there's such fear and loathing.
- 2:57Historically. That's the concern.
- 2:59It's going to give me cancer. Doesn't do it, folks.
- 3:02In fact, testosterone is anti proliferative.
- 3:06There are studies supporting that it can suppress breast
- 3:09cancer. Women on testosterone therapy
- 3:13had lower incidences of breast cancer.
- 3:16Women with breast cancer are now being treated with testosterone.
- 3:22In fact, there's a drug in its final stages of research,
- 3:28Enobosam. Enobosam is the name of the
- 3:30drug. It sounds like a tribe in
- 3:32Africa. Enobosam is the name of the
- 3:35drug. It's going through the FDA
- 3:36approval process right now and it is a testosterone analog.
- 3:41It stimulates testosterone receptors.
- 3:44And what they're finding is that women with stage 4 breast cancer
- 3:48do better with this drug. Even those who have estrogen and
- 3:52progesterone receptor positive cancers.
- 3:55They live longer, they live better.
- 3:57Fascinating. Begs the question why you
- 4:01produce a good drug when we have testosterone that in fact hits
- 4:06testosterone receptors and is a much more natural way to do it.
- 4:11Why not just go women testosterone?
- 4:14The answer to the question is you cannot patent testosterone.
- 4:18It's generic. For a drug company to turn
- 4:21testosterone receptor stimulation into a profitable
- 4:26product requires a patent, requires a drug that is unique
- 4:32and separate from testosterone, even though it does the same
- 4:36thing. Now, in order to sell this to
- 4:39women and to the medical community at large, they're
- 4:42going to have to make you fear testosterone even further.
- 4:45They're going to say this drug can do what testosterone does
- 4:50without all the negative stuff, you know, acne and hair growth
- 4:54and all the folks that doesn't occur unless you're getting
- 5:00you're getting treated by a provider who's not sensitive,
- 5:03thoughtful and knowledgeable. Properly dose testosterone in
- 5:07women is a gift to mankind. You will be stronger, smarter,
- 5:12faster, better. And no, you're not going to grow
- 5:15a beard. And no, the breast cancer rates
- 5:17is no evidence that it's going to increase none.
- 5:20So I'm seeing a lot of positives here.
- 5:22I'm not seeing a lot of negatives.
- 5:24I don't, by the way, I've been doing this in my practice for 15
- 5:27years. Very grateful women, very
- 5:29grateful families, very enriched.
- 5:32It does not hyper sexualize, it restores normal baseline.
- 5:37It does not 'cause aggression. You know, the the aggressive,
- 5:40grumpy, miserable old man or grumpy old lady, their
- 5:44testosterone deficient more likely testosterone has a
- 5:47calming effect in the vast majority of people.
- 5:51So fear of for of cancer not there for breast cancer?
- 5:56How about prostate cancer? Isn't testosterone going to
- 6:00explode my risk? Well, that was the thinking for
- 6:04many, many years. It's remarkable how in medicine
- 6:08dogma becomes petrified. We've been talking about this a
- 6:11lot with regard to the PSA and prostate cancer treatment.
- 6:16It's very hard to get doctors in medicine to move from an
- 6:21established belief system, even if the belief system is built on
- 6:27weak ground and thus it is with testosterone and prostate
- 6:31cancer. Have to credit doctor Abraham
- 6:34Morgan Taylor and his fine book Testosterone for Life as being a
- 6:38real thought leader in this space.
- 6:40It turns out that the Doctor Who originally associated
- 6:44testosterone with amplified cancer risk, or with stimulating
- 6:49cancer that's already there, based his findings on a single
- 6:54case, one case. It became dogma.
- 6:57It became part of the accepted fund of knowledge that was
- 7:04unequivocal. And now it's being challenged.
- 7:07And it should. It turns out that men with low
- 7:11testosterone have higher cancer rates.
- 7:14It also turns out that there is not a direct dissociation
- 7:18between the blood level of testosterone and the level
- 7:21inside the prostate gland. In other words, the prostate
- 7:25gland reaches a saturation point of testosterone beyond which has
- 7:32no effect. So a man can receive therapeutic
- 7:35testosterone therapy, enhancing his vitality, libido, strength,
- 7:40energy, decreasing muscle aching, stabilizing arthritic
- 7:44joints, improving cognitive function, all fabulous without
- 7:49worrying about is it going to give me prostate cancer.
- 7:52Evidence does not support that. That's not just me saying it,
- 7:57that's consensus opinion amongst andrology specialist like me,
- 8:01people that do this all the time and look at the research as
- 8:05well. Look, if you're on testosterone
- 8:08therapy and you're a woman, you can still get breast cancer but
- 8:12the testosterone didn't contribute.
- 8:14Same thing for men. If you're on testosterone
- 8:16therapy, you can get prostate cancer, but the T unlikely to
- 8:21have any factor in that event. What about the PSA levels?
- 8:28Testosterone therapy does not by and large increase PSA levels.
- 8:33They have evidence of this over many years, hundreds and
- 8:36hundreds of patients. If your PSA goes up, it's not
- 8:39usually associated with the testosterone therapy.
- 8:43Well, what if you, what if you have a high PSA, an abnormal
- 8:49MRI, and you're fearful that if you put testosterone in your
- 8:53system, you're going to pour gas on a fire?
- 8:56Turns out not to be the case. We're looking at the research
- 9:00regarding men who have abnormal Psas, abnormal Mris, and we're
- 9:05just not seeing it happen. This idea of prostatic
- 9:09saturation is real. The concept that testosterone
- 9:14therapy is going to explode prostate cancer is a widely held
- 9:20fear that deserves to be put aside.
- 9:23You should not stop your testosterone therapy because PSA
- 9:27went up. You should not abandon its
- 9:30benefits because of the lab test.
- 9:34It's worthy of reflection, and we all have to make our own
- 9:37decisions, guys and gals, right? What do we want to see happen
- 9:41for our health? I'm an advocate of taking
- 9:45advantage of a known benefit, especially when weighed up
- 9:49against a theoretical concern that research does not support.
- 9:54So men, if you're feeling symptoms of low testosterone,
- 9:57you needn't fear your prostate being at risk because you're now
- 10:01on testosterone. Now we are gathering growing
- 10:06experience with men who have prostate cancer and have chosen
- 10:14to go on testosterone therapy. Now, that is not standard of
- 10:18care. Standard of care is to castrate
- 10:21them. But there's a growing cluster of
- 10:24men that just don't want to live that way.
- 10:26And they say to me and to God, doctors like me, you know, Doc,
- 10:30I understand the prevailing dogma.
- 10:33I understand the theory that giving testosterone will
- 10:37accelerate to prostate cancer growth.
- 10:40I understand all that. I'm also cognizant of the fact
- 10:44that that theory may not be valid and that there's growing
- 10:49evidence that it doesn't hold. Therefore, in the contest
- 10:54between a theoretical adverse effect and a tangible benefit, I
- 10:58choose the benefit. Men should have their
- 11:01prerogative honored. So I have some gentlemen in my
- 11:04practice who were on testosterone therapy, developed
- 11:09prostate cancer. The testosterone therapy was
- 11:11stopped, and their quality of life collapsed.
- 11:15Their executives, their leaders, their brain didn't work right.
- 11:19They couldn't keep up at work. Their relationship with their
- 11:23wife started to decline as they became physically disconnected.
- 11:28Libido faded, erections faded. Strength, confidence, the big
- 11:32variable. And upon reflection, they opted
- 11:36to go back on testosterone therapy and thus far, thriving.
- 11:40Will they someday die of prostate cancer?
- 11:43They may, but that may have occurred anyhow.
- 11:47So you have to think about the risks based on the best research
- 11:52and not an emotional reaction based upon previously held
- 11:58beliefs that have been since repudiated to a large extent.
- 12:04So testosterone is safe for prostates?
- 12:06It is safe for breast. What about the heart?
- 12:10You know, I've heard that it's going to cause hardening of the
- 12:12arteries. Once again, the information does
- 12:15not support that consequence. A study looking at men on
- 12:20testosterone therapy found no increased incidence of heart
- 12:24attack, stroke, none. They found that the men had
- 12:27better strength, better libido, lean body mass improved.
- 12:32This was a published study in New England Journal of Medicine.
- 12:34They looked at these parameters. What I found interesting.
- 12:37OK, so those findings are very affirmative.
- 12:40The conclusion of the article reflected the mainstream
- 12:45medicines bias against testosterone despite absence of
- 12:50harm and despite evidence of benefit.
- 12:53The conclusion was, yeah, but we still don't recommend
- 12:57testosterone therapy. But why wouldn't you?
- 13:00Why would you say that it can help these things?
- 13:03They didn't consider improving muscle, improving the libido
- 13:09function, improving vitality. They didn't consider that
- 13:13valuable enough to justify testosterone therapy.
- 13:17How absurd. Falling and breaking a hip is a
- 13:21consequence that leads to early death, and it can be prevented
- 13:27by virtue of strength, power, muscle integrity and bone
- 13:31integrity, all of which are improved by testosterone.
- 13:35I like to say my patients don't break when they fall, they
- 13:38bounce. They bounce.
- 13:41So testosterone and heart disease is no strong
- 13:43correlation. The evidence does not support
- 13:47hardening of the arteries. You think about it practically,
- 13:50right? Who has the most testosterone in
- 13:52the world? Young men?
- 13:54Do they get heart disease or cancer of the prostate?
- 13:56No and no. All right, I get it.
- 13:59That's kind of intuitive. The research, however, supports
- 14:02the same conclusions. Who's afraid of testosterone?
- 14:06You should not be. Is your family doc afraid of it?
- 14:10Is urologist afraid of it? It's an uncomfortable space for
- 14:15them. Why?
- 14:16Because it's not been accepted as a legitimate medical need
- 14:23just because you're weak and feeble, just because ladies,
- 14:28you've lost your libido, just because you're can't lose that
- 14:31mid abdominal fat. It's not really a medical thing
- 14:34now, is it? Because you're not getting a
- 14:35heart attack, you're not dying. The concept of that which is
- 14:39medical and justifiable versus that which enhances vitality and
- 14:44Wellness are two separate spheres.
- 14:48And your insurance reimbursed conventional Dr. has to stay
- 14:52within that lane if they're going to ever give you
- 14:55testosterone. Not only how are they inhibited
- 15:00from the freedom to do so because of the prevailing dogma,
- 15:04but the dose levels. That's worth mentioning.
- 15:07How much testosterone should a man or women receive?
- 15:11How do you know when the dose is correct?
- 15:13You can't go blood. Blood levels.
- 15:15The blood levels are misleading. And here's part of the reason.
- 15:19Because they are adjusted for age.
- 15:21Well, that's just stupid. I don't want the testosterone
- 15:25level of a, you know, 60 something year old man.
- 15:28I want the 35 level. That's what we're aiming at.
- 15:31What's wrong with that? Better vitality, better
- 15:34strength, better energy, all good.
- 15:37When testosterone therapy is rendered to men or women, I
- 15:41don't remember. There are two broad types of
- 15:43testosterone that we measure in the blood, total and free.
- 15:49The total testosterone includes that which is kept in storage
- 15:52form, not biologically active, cannot connect to those
- 15:57testosterone receptors. Only the free testosterone can
- 16:01do that. It turns out as we get older, we
- 16:04have a larger capacity to store testosterone, thereby skewing
- 16:08the lab test. So if the top level for the lab
- 16:12is, let's call it 700 and you test at 8 or 900, doctors going
- 16:17to get nervous. Oh, your level's too high.
- 16:20What about the free testosterone?
- 16:22And more importantly, how are you feeling?
- 16:25The way to adjust testosterone is based on the symptom
- 16:28objective being achieved. I feel great, doc.
- 16:32My energy's good, libido's good, Brain is clear.
- 16:35This is a good space. That's the right dose.
- 16:38If you haven't achieved, if a person, a patient hasn't
- 16:41achieved the objectives, the dose should be adjusted upward.
- 16:46As long as there are no negative consequences.
- 16:50Estrogen levels can go up. They need to be monitored.
- 16:53The hemoglobin, hematocrit, the amount of red blood cells can go
- 16:56up. If it goes up too high, the
- 16:59blood can get too thick, present an increased risk of clotting
- 17:03that needs to be monitored but easily managed.
- 17:06How about like acne? If that happens, it's a sign
- 17:09that maybe you're at the upper threshold.
- 17:12But in the absence of any negative side effect, patients
- 17:15should be honored in their quest to get to the best level.
- 17:19Sometimes you don't know it until you're there.
- 17:22Same thing holds true for women. Same thing.
- 17:25If you're feeling great and all the symptoms are addressed,
- 17:30that's your level. Can the blood test tell you what
- 17:33to do? Doctors who use blood tests to
- 17:35adjust labs, and they use that exclusively by manifesting a
- 17:40limitation in their appreciation of the functional aspect of the
- 17:45hormone. Look, I get labs, We all should
- 17:49monitor it. Yes, it's reasonable, it gives
- 17:53guidance. But a lab should never
- 17:56neutralize or trump your experience symptomatically.
- 18:01So to fear testosterone? Absolutely not.
- 18:04What else is good about it? Well, studies have shown that
- 18:07women have has who have had hysterectomies or men who've
- 18:10been castrated have a higher incidence of dementia.
- 18:14It appears that testosterone is neuroprotective.
- 18:18So once again I ask, why is the world so afraid of testosterone
- 18:24and why are doctors so scared of it?
- 18:28Look, I understand ignorance breeds fear, and unless a doctor
- 18:34or a nurse practitioner provider spends a lot of time researching
- 18:40the nuances of testosterone therapy, all they have time for
- 18:44is enough time to absorb the dogma, and that can often be a
- 18:49knee jerk reflex. And just like that paper
- 18:52highlighted, even in the presence of abundant positive
- 18:56findings, the bias against it is still not always defeated.
- 19:01Every decision you make in life, whether it's to walk or drive to
- 19:04the store, whether it's to use testosterone or not, has a risk
- 19:09benefit equation to be contemplated.
- 19:13It's not reasonable to require of anything, including
- 19:18testosterone, for it to be 100% risk free.
- 19:22That defies practical possibilities, and it eliminates
- 19:26a lot of really positive things from happening in your life.
- 19:30Think about that. What can you do that's fun?
- 19:34What can you do that's good for you?
- 19:35That carries like 0 risk. Not many things.
- 19:39Not many things at all. So let's put testosterone in
- 19:42that category. Do you have to use it?
- 19:45Well, if you want to live your best life, I'd say yes, but it's
- 19:49your prerogative. And defining best life is
- 19:52subjective, right? For some people, they don't mind
- 19:55shrinking. They don't mind, you know, the
- 19:57oh I'm old, I can't do it thing. I get that too.
- 20:01You know, sometimes it's comfortable to just say, well, I
- 20:05can't because after all, I'm ex age and I'm old, you know, kind
- 20:09of get a free pass. Society will expect less out of
- 20:13you if you give them that mantra.
- 20:16I advise you not to do it folks. Stay alive, stay vital.
- 20:20It's a better way to live life. Death will come.
- 20:24And when it does, your rest will be bestowed upon you.
- 20:27Until then, let's not be dogmatically fearful.
- 20:31Let's look at ways we can maintain our vitality, And let's
- 20:35give testosterone a new view. Man, woman, prostate cancer or
- 20:42not, breast cancer or not, the evidence is growing regarding
- 20:46its broad value and these fear factors.
- 20:49Who's afraid of testosterone? I dare say the ill informed, the
- 20:55ignorant, the dogmatic. That's kind of not nice too, is
- 20:58it? Shouldn't call him ignorant.
- 20:59Well, ignorant is not really a criticism, it just means a lack
- 21:01of knowledge. And sometimes knowledge changes
- 21:05behavior. Although it has been said that
- 21:09the way a doctor convinces his colleagues that he's right and
- 21:13they're wrong is to wait for them to die.
- 21:17It's hard. It's hard for an expert to
- 21:19change an opinion that has defined their identity.
- 21:22Well, folks, I hope you gained something today.
- 21:25A little bit of insight. The evidence is there.
- 21:28The evidence is growing. Look into it yourself.
- 21:31That's a beautiful thing, right? You can AI everything I said and
- 21:35read what's happening. Well, until next time, gang.
- 21:38It's been a pleasure. I'll talk to you then.