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Midnight Drop: How a $16M Alzheimer's Miracle Vanished
Midnight Drop: How a $16M Alzheimer's Miracle Vanished
Hope turned to doubt overnight: a $16 million NIH grant, hundreds of patients in trials, and a drug called simufilam that rested on a disputed protein called filamin A - then every criminal charge was dropped at midnight. What happened to the biomarker data, the images that triggered retractions, and the independent verification that never arrived?
In this episode, we lay out the timeline from the 2012 Journal of Neuroscience paper that introduced PTI-125 to the 2025 courtroom where charges were dismissed, tracing the grant, the clinical…
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