Latest / Fork U with Dr. Terry Simpson / FORK U #100 — The Hall of Fame and Shame
Transcript
- 0:04>> Dr. Terry Simpson: This is it, episode 100 of 4Q. Over the past 99
- 0:11episodes, we have gone from the blue zones to the
- 0:14bird flu, from Kellogg's enemas to cholesterol
- 0:17chemistry, and from goat gland hucksters to the
- 0:20microbiome. Today, we are celebrating the best and
- 0:23the worst. The scientists who changed medicine and
- 0:27the scammers who tried to sell it back to us in a
- 0:29bottle. Welcome to Fork, you Hall of Fame and
- 0:32shame. I am your Chief Medical Explanationist, Dr.
- 0:38Terry Simpson, and this is Fork U Fork University,
- 0:43where we bust myths, make sense of the madness,
- 0:46and teach you a little bit about food and
- 0:48medicine. I'm going to start with Ancel Keys, the
- 0:54most misunderstood scientist of today, but not of
- 0:58his time. Ancel Keys gave us the Mediterranean
- 1:01diet long before influencers turned olive oil into
- 1:05content. Ancel Keys didn't guess. He measured. He
- 1:09didn't speculate. He studied. Keys built one of
- 1:13the most careful and longest running cohort
- 1:16studies in all of medical history. He and his team
- 1:19went village by village across seven countries,
- 1:22collecting everything people ate, sending those
- 1:25foods back to laboratories for precise nutrient
- 1:27analysis. Every year, they perform blood work,
- 1:30EKGs, physical examinations. They comb through the
- 1:34hospital charts of the patients, death
- 1:36certificates and medical records, not for months,
- 1:39but for decades. That is science the hard way.
- 1:42Observation, precision, patience. For critics like
- 1:47Gary Taubes, who claim Keys left out countries,
- 1:50that accusation only proves he never read Keyes
- 1:54actual papers. Keyes didn't study nations. He
- 1:58studied cohorts of men in villages within those
- 2:01nations, following them year after year to see how
- 2:04the diet and diseases progressed. Keyes wasn't
- 2:08chasing fame. He was following evidence. Even
- 2:12without today's molecular tools, his data pointed
- 2:15straight to what modern lipid science later
- 2:18confirmed. Apolipoprotein B, the protein that
- 2:21escorts LDL cholesterol, is actively transported
- 2:25into arterial walls and starts atherosclerosis,
- 2:29the root of heart disease. So when modern
- 2:32influencers dismiss Keys with a tweet or a podcast
- 2:35rant, remember, they've got microphones, Keys has
- 2:39data, they have followers. Keys left us with the
- 2:43foundation of, ah, preventive cardiology. And if
- 2:45you want to honor him, drizzle olive oil instead
- 2:49of conspiracy. And I owe a Special thanks to Dr.
- 2:52Harry Blackburn, who worked with Keys at Minnesota
- 2:55and still shares stories from those early days of
- 2:58the seven country study, a labor of love that
- 3:01defined modern nutritional science. I'm going to
- 3:05go back in time now to Dr. Frederick Banting and
- 3:08Charles Brest and the children who woke up. I want
- 3:12you to picture this. 1922, the University of
- 3:17Toronto, Dr. Banting and a medical student named
- 3:20Charles best discovered how to collect insulin out
- 3:24of pancreases of lots of animals. They purified
- 3:28that insulin. And then Dr. Frederick Banting, in
- 3:31one of the most amazing moments in modern
- 3:34medicine, went to a children's hospital. Here,
- 3:37children had slipped into a coma, and families
- 3:40were simply waiting for them to die from what we
- 3:43now know as type 1 diabetes. Instead, he went by
- 3:48those children one at a time and injected insulin.
- 3:52And the children woke up, and the children were
- 3:55able to live normal lives because of this
- 3:58remarkable discovery of insulin. Their parents
- 4:01were able to hug them again, talk to them again.
- 4:04And many of these children lived in their 70s and
- 4:0680s, when they were expected to die as teenagers.
- 4:10I want you to think back to the 1920s, when people
- 4:12said, oh, they could feed, and their, uh, food was
- 4:15much better then, and those parents fed them. But
- 4:17diet alone didn't stop death. Good science did,
- 4:21and it still does a century later. Banting sold
- 4:25that patent for a dollar because he thought it
- 4:27should belong to everybody. Too bad modern
- 4:29pharmaceuticals don't do the same.
- 4:32In one of my favorite episodes about Dr. Kinehara
- 4:35Takaki and the first vitamin. So decades before
- 4:39anybody knew the word vitamin, There was a
- 4:41Japanese surgeon, Dr. Kinohara, and he had noticed
- 4:45that sailors were dying of what we now know as
- 4:47beriberi on long voyages. Dr. Kinohara was a very
- 4:51careful surgeon. He had been initially trained in
- 4:53eastern surgery, but he became retrained in
- 4:56western surgery, actually going to london and
- 4:59learning at St Mark's Hospital. He even studied
- 5:02with people like Charles mayo, who was actually a
- 5:04fellow student of his. When he went back, he used
- 5:08epidemiology, and he learned epidemiology from
- 5:11John snow himself, the guy who discovered that the
- 5:14broad street water pump Was the source of cholera
- 5:18in london. Those principles of epidemiology
- 5:21brought kitahara back, and he noticed that the
- 5:24sailors who had a more vigorous diet, balanced
- 5:28diet, didn't suffer from symptoms of beriberi, and
- 5:32he attributed to what became later known as
- 5:34thiamine. Had Dr. Kinohara lived longer, he would
- 5:37have shared the nobel prize for the discovery of
- 5:40thiamine. But unfortunately, he died. But his
- 5:43careful discovery, his careful research, his
- 5:45careful epidemiology saved more people in the
- 5:48japanese navy than anything else, because more
- 5:52people died in the Japanese imperial navy from
- 5:54beriberi than any died from bullets. And he's also
- 5:59known for bringing Japan into modern medicine.
- 6:04Next, I want to come back to someone who's a
- 6:06contemporary of mine, Dr. Leonard Hayflick. He
- 6:09unfortunately died a few years ago, but he was the
- 6:11original longevity doctor. In 1961, Leonard
- 6:16Hayflick, a PhD, wasn't studying nutrition. He was
- 6:19studying life itself. He was looking at cell
- 6:22cultures. And he discovered that human cell
- 6:25cultures divided about 50 times, stopped, went
- 6:27into senescence and then ultimately died. That
- 6:31became the Hayflick limit. And that simple
- 6:34observation has rewritten biology. It proved that
- 6:37aging isn't mystical or mental. It occurs at a
- 6:40cellular level. Each division of a cell uses a bit
- 6:44of our genetic clock until the cell retires from
- 6:47service. He wasn't finding out about food or
- 6:50supplements. It was truth. It became the
- 6:53foundation of regenerative medicine and cell
- 6:55biology, showing us why cells repair slow and
- 6:58rest. Learning the first bit about telomeres, if
- 7:01there was ever a real longevity doctor. That whole
- 7:05science started with Leonard Hainfla. No ring
- 7:07light, no powders, just a microscope and the
- 7:10courage to question dogma.
- 7:13Speaking of modern nutrition, two decades after
- 7:16Keys came the DASH diet and the Portfolio Diet
- 7:19teams. Um, DASH stands for the Dietary Approach to
- 7:23Stop Hypertension. And that came from a dream team
- 7:26of scientists. At Johns Hopkins, it was Dr. Lauren
- 7:29Sepel who led the NIH. At Pennington Biomedical,
- 7:32Dr. George Bray, Donna Ryan, Catherine Champagne
- 7:35built the menus. And at Harvard, Dr. Frank Sachs
- 7:37crunched the numbers. Their 1997 study proved that
- 7:41a diet rich in fruits, vegetables, whole grains,
- 7:44low fat dairy and low salt could lower blood
- 7:47pressure without weight loss. Then there was the
- 7:50portfolio diet. Dr. David Jenkins and his team
- 7:53from the University of Toronto, again, like Dr.
- 7:56Banting and Best, they discovered about fiber and
- 8:00how it was the first drug tools used against high
- 8:03cholesterol. Their combination of soy nut soluble
- 8:05fiber and plant sterols cut LDL by up to 17%.
- 8:09Culinary medicine at its finest. And yet some will
- 8:12say, we need more salt. The DASH team proved
- 8:14otherwise. Unless, of course, you're selling a
- 8:16mango flavored electrolytes on TikTok.
- 8:19And now let's talk about a place where surgery
- 8:23became science. If you ever find yourself in
- 8:26Edinburgh, skip the kilt shops and go to the
- 8:29Surgeons Hall Museum. There you will find where
- 8:32Lister showed how antisepsis improved surgical
- 8:35outcomes. There you will find where Sime, who was
- 8:39actually not only Lister's chairman, but father in
- 8:42law, careful anatomy left dissections on
- 8:45operations that we still use and I have used to
- 8:48this day. There you will find where James Young
- 8:51Simpson discovered how chloroform couldn't be used
- 8:54as an anesthetic in surgery. And you will find a
- 8:57Young medical student named Arthur Conan Doyle
- 9:00studied under Dr. Jose, that sharp eyed
- 9:03diagnostician who inspired Sherlock Holmes. That's
- 9:07where medicine learned to observe, deduce and
- 9:09prove. And from those halls the art of observation
- 9:12became the science of evidence. It was the
- 9:15birthplace of modern diagnosis and the foundation
- 9:17of modern American education. We'll be touring
- 9:21that museum on my TikTok channel this November
- 9:24because understanding where science began and
- 9:26where medicine and surgery begin as it's important
- 9:29to know where it's going. But hall of Fame we also
- 9:33have the hall of Shame.
- 9:38We're going to start with Gary Brecke, the
- 9:40biohacking Hypebend Every generation has a snake
- 9:43oil salesman. Ours just streams in high
- 9:46definition. Gary Brecke calls himself a biologist
- 9:49who can predict your date of death and move it for
- 9:51a fee. No medical degree, no doctorate. He has a
- 9:54bachelor's degree and some borrowed scrubs. He
- 9:56went to chiropractic school but apparently never
- 9:59finished. He sells hydrogen water bottles,
- 10:01claiming that There are over 1400 studies proving
- 10:03it's the best in the world. There aren't that many
- 10:05studies. He says that cold plunges melt flat. They
- 10:08don't. And if they did, every Alaskan fisherman
- 10:11would look like Thor. He and his buddies yuck it
- 10:14up online on his podcast, calling it science, but
- 10:17it's show business with a pulse oximeter. Then
- 10:21there's Dr. No, she's not a doctor. It's actually
- 10:24just Barbara O', Neill, the preacher, not the
- 10:27professor. She's more Seventh Day Adventist than
- 10:31scientists. She claims that cayenne pepper can
- 10:33stop a heart attack and cholesterol is a
- 10:35pharmaceutical plot. She charges thousands of
- 10:38dollars for her seminars while ignoring decades of
- 10:40research. The Crestro that I use costs $0.70 a
- 10:44month. I'm pretty sure she's the only one making
- 10:46money off of that.
- 10:50Now to the shirtless salesman of supplements and
- 10:53scams. Compare the scientists between the
- 10:55Mediterranean dash and portfolio diets to today's
- 10:58influencers and you'll see two different species.
- 11:01The researchers spent decades on data. The
- 11:04salesmen spend minutes on marketing. There's Paul
- 11:09Saladino, the carnivore who discovered fruit when
- 11:11steak stopped selling. The salt slingers hawking
- 11:14electrolyte powder for $39.99 a bag. And Dr. Uh,
- 11:17Gundry, the never shirtless but always pedantic ex
- 11:21surgeon selling bean guard for 60 bucks a month.
- 11:23And of course, who can forget the liver king whose
- 11:26muscles came from a needle, not cow liver.
- 11:31Scientists understand the chemistry and biology
- 11:34and scammers understand lightning and marketing.
- 11:37And so keys with the Hitchens of his day and able
- 11:39to slay nonsense with a sentence. But most
- 11:42scientists aren't showmen. They're too busy doing
- 11:44their work. The scammers pretend their wealth came
- 11:47from helping people, but it comes from powders and
- 11:49placebos. So next time someone with a six pack on
- 11:52a Shopify account say they reinvented nutrition,
- 11:55remember, science doesn't need an affiliate link.
- 12:02And that brings us to the Rio Heroes. The heroes
- 12:05that you may know in your community today. They
- 12:07were the doctors, the nurse, the therapists, the
- 12:09healthcare workers who showed up every day during
- 12:12the pandemic before we had a vaccine. While the
- 12:15supplement salesmen surfed and sold powders, these
- 12:17people suited up and saved lives. Give your fellow
- 12:22nurse and doctor who were present at that time a
- 12:24handshake at the end of 100 episodes. Here's what
- 12:29I Science doesn't need to be sexy to save lives.
- 12:33Our job, our mission, is to build the bridge
- 12:37between real scientists and you, the public. My
- 12:41background's in science and medicine, but my
- 12:42mission is to bring you the quiet truth from labs
- 12:45and hospitals, but not under a ring light. And
- 12:47it's my joy to share the work of people whose idea
- 12:50of glory is a pat on the back from a colleague,
- 12:52not a link on Amazon. Because around every life
- 12:56saving discovery is a scientist who will Never
- 12:58trend on TikTok, but they're the ones who actually
- 13:01change the world. That's what Forku has always
- 13:04been about. Separating noise from nutrition, hype
- 13:08from health, and reminding you that evidence
- 13:10always outlasts the algorithm. This has been Fork
- 13:17U Fork University, researched and written by me,
- 13:20Dr. Terry Simpson, all things Audios and
- 13:23production by Simpler media and the pod God
- 13:25himself, Mr. Eboterra. For references and more
- 13:28episodes, visit forku.com and
- 13:30yourdoctorsorders.com and remember this. I am a
- 13:34board certified physician, but I am not your
- 13:36physician. This podcast is for education, not
- 13:39personal medical advice. After a hundred episodes,
- 13:43thank you for listening, for thinking and being a
- 13:46part of this journey. Here's to the next hundred
- 13:49and to science over salesmanship. Hey Evo, you've
- 13:57been here for all 100 episodes of Fork you and a
- 14:00few of the episodes and our trials before that.
- 14:03Who are the heroes and quacks in this enterprise?
- 14:05And thanks for making me sound better than I am.
- 14:11It has been truly my pleasure, my friend. Oh, and
- 14:15if I'm the hero, can I wear a cape? It.